Availability of health facilities and untilization of maternal and newborn postnatal care in rural Malawi

Background: This study explored the role of health facility availability as it relates to maternal and newborn PNC use in rural Malawi. Methods: Malawi Demographic and Health Survey (MDHS) 2015–16 data, MDHS 2015–16 household cluster GPS data, Malawi Service Provision Assessment (MSPA) 2013–14 data and MSPA 2013–14 facility GPS data were used. Household clusters were spatially linked with facilities using buffers. Descriptive analyses were performed and generalized estimating equations (GEE) were used to determine the effects of having different types of facilities at varying distances from household clusters on receipt of maternal and newborn PNC in rural Malawi. Results: In rural Malawi, around 96% of women had facilities providing PNC within 10 km of where they live. Among women who have clinic-level facilities within 5 km of where they live, around 25% had clinic-level facilities that provide PNC. For rural women who gave birth in the past 5 years preceding the survey, only about 3% received maternal PNC within 24 h and about 16% received maternal PNC within the first week. As for newborn PNC, 3% of newborns had PNC within 24 h and about 26% had newborn PNC within the first week. PNC mostly took place at facilities (94% for women and 95% for newborns). For women who delivered at home, having a health center providing PNC within 5 km was positively associated with maternal and newborn PNC. For women who delivered at facilities, having a health center providing PNC within 5 km was positively associated with maternal PNC and having a health center providing PNC between 5 km and 10 km was positively associated with both maternal and newborn PNC. Regardless of the place of delivery and distance band, having a clinic-level facility providing PNC did not have significant positive effects on maternal and newborn PNC. Conclusions: Providers should be trained to perform quality PNC at all facilities. It would also be important to address concerns related to health workers. Lastly, it would be key to increase community awareness about the importance of seeking timely PNC and about the utility of lower-level facilities for receiving preventative PN

Measurement of Content of 226Ra in Drinking Water From Some States of Mexican Republic by Liquid Scintillation Method

To assess the quality of drinking water in respect to the content of radioactivity, usually is carried out an screening program in the locations of interest, that program consist in pick representative samples of drinking water from the wells in that locations, water samples are analyzed to measuring the gross alpha/beta radioactivity by a low background proportional counter or a liquid scintillation system. When some sample exceeds the normative limit then it must be known which radionuclides are in that sample. Expected radionuclides in water are the NORM (normal occurring radioactive material) from the natural radioactive chains. 226Ra is frequently present in drinking water and is one of most important radionuclide because its “radiotoxicity”, the WHO [World Health Organization, Guidelines for drinking-water Quality, (2016)] recommends a reference level for 226Ra of 1 Bq/L (the dose coefficient for 226Ra is 2.8 x 10-7 Sv/Bq). From a national program of drinking water screening in the Mexican Republic, the samples that exceeded the national normative limits were picked again in the same well and analyzed by LS (liquid Scintillation), using the method of two phases with a not water miscible scintillator cocktail. Results of concentrations of 226Ra from drinking water are presented. In general the content of 226Ra in drinking water samples was lower that the guide values recommended for the WHO

Superelastic damping at nanoscale in ternary and quaternary Cu-based shape memory alloys

Superelasticity is a characteristic thermomechanical property in shape memory alloys (SMA), which is due to a reversible stress-induced martensitic transformation. Nano-compression experiments made possible the study of this property in Cu–Al–Ni SMA micropillars, showing an outstanding ultra-high mechanical damping capacity reproducible for thousands of cycles and reliable over the years. This scenario motivated the present work, where a comparative study of the damping capacity on four copper-based SMA: Cu–Al–Ni, Cu–Al–Be, Cu–Al–Ni–Be and Cu–Al–Ni–Ga is approached. For this purpose, [001] oriented single-crystal micropillars of comparable dimensions (around 1 µm in diameter) were milled by focused ion beam technique. All micropillars were cycled up to two hundred superelastic cycles, exhibiting a remarkable reproducibility. The damping capacity was evaluated through the dimensionless loss factor η, calculated for each superelastic cycle, representing the dissipated energy per cycle and unit of volume. The calculated loss factor was averaged between three micro-pillars of each alloy, obtaining the following results: Cu–Al–Ni η = 0.20 ± 0.01; Cu–Al–Be η = 0.100 ± 0.006; Cu–Al–Ni–Be η = 0.072 ± 0.004 and Cu–Al–Ni–Ga η = 0.042 ± 0.002. These four alloys exhibit an intrinsic superelastic damping capacity and offer a wide loss factor band, which constitutes a reference for engineering, since this kind of micro/nano structures can potentially be integrated not only as sensors and actuators but also as dampers in the design of MEMS to improve their reliability. In addition, the study of the dependence of the superelastic loss factor on the diameter of the pillar was approached in the Cu–Al–Ni–Ga alloy, and here we demonstrate that there is a size effect on damping at the nanoscale.Fil: Gómez Cortés, J.F.. Universidad del País Vasco; EspañaFil: Fuster, Valeria de Los Angeles. Universidad del País Vasco; España. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario. Instituto de Física de Rosario. Universidad Nacional de Rosario. Instituto de Física de Rosario; ArgentinaFil: Pérez Cerrato, M.. Universidad del País Vasco; EspañaFil: Lorenzo, P.. Universidad del País Vasco; EspañaFil: Ruiz Larrea, I.. Universidad del País Vasco; EspañaFil: Breczewski, T.. Universidad del País Vasco; EspañaFil: Nó, M. L.. Universidad del País Vasco; EspañaFil: San Juan, J. M.. Universidad del País Vasco; Españ

Pre-sleep feeding, sleep quality, and markers of recovery in division I NCAA female soccer players

Pre-sleep nutrition habits in elite female athletes have yet to be evaluated. A retrospective analysis was performed with 14 NCAA Division I female soccer players who wore a WHOOP, Inc. band – a wearable device that quantifies recovery by measuring sleep, activity, and heart rate metrics through actigraphy and photoplethysmography, respectively – 24 h a day for an entire competitive season to measure sleep and recovery. Pre-sleep food consumption data were collected via surveys every 3 days. Average pre-sleep nutritional intake (mean ± sd: kcals 330 ± 284; cho 46.2 ± 40.5 g; pro 7.6 ± 7.3 g; fat 12 ± 10.5 g) was recorded. Macronutrients and kcals were grouped into high and low categories based upon the 50th percentile of the mean to compare the impact of a high versus low pre-sleep intake on sleep and recovery variables. Sleep duration (p = 0.10, 0.69, 0.16, 0.17) and sleep disturbances (p = 0.42, 0.65, 0.81, 0.81) were not affected by high versus low kcal, PRO, fat, CHO intake, respectively. Recovery (p = 0.81, 0.06, 0.81, 0.92), RHR (p = 0.84, 0.64, 0.26, 0.66), or HRV (p = 0.84, 0.70, 0.76, 0.93) were also not affected by high versus low kcal, PRO, fat, or CHO consumption, respectively. Consuming a small meal before bed may have no impact on sleep or recovery

QoS Analysis for a Non-Preemptive Continuous Monitoring and Event Driven WSN Protocol in Mobile Environments

Evolution in wireless sensor networks (WSNs) has allowed the introduction of new applications with increased complexity regarding communication protocols, which have to ensure that certain QoS parameters are met. Specifically, mobile applications require the system to respond in a certain manner in order to adequately track the target object. Hybrid algorithms that perform Continuous Monitoring (CntM) and Event-Driven (ED) duties have proven their ability to enhance performance in different environments, where emergency alarms are required. In this paper, several types of environments are studied using mathematical models and simulations, for evaluating the performance of WALTER, a priority-based nonpreemptive hybrid WSN protocol that aims to reduce delay and packet loss probability in time-critical packets. First, randomly distributed events are considered. This environment can be used to model a wide variety of physical phenomena, for which report delay and energy consumption are analyzed by means of Markov models. Then, mobile-only environments are studied for object tracking purposes. Here, some of the parameters that determine the performance of the system are identified. Finally, an environment containing mobile objects and randomly distributed events is considered. It is shown that by assigning high priority to time-critical packets, report delay is reduced and network performance is enhanced.This work was partially supported by CONACyT under Project 183370. The research of Vicent Pla has been supported in part by the Ministry of Economy and Competitiveness of Spain under Grant TIN2013-47272-C2-1-R.Leyva Mayorga, I.; Rivero-Angeles, ME.; Carreto-Arellano, C.; Pla, V. (2015). QoS Analysis for a Non-Preemptive Continuous Monitoring and Event Driven WSN Protocol in Mobile Environments. International Journal of Distributed Sensor Networks. 2015:1-16. https://doi.org/10.1155/2015/471307S1162015Arampatzis, T., Lygeros, J., & Manesis, S. (s. f.). A Survey of Applications of Wireless Sensors and Wireless Sensor Networks. Proceedings of the 2005 IEEE International Symposium on, Mediterrean Conference on Control and Automation Intelligent Control, 2005. doi:10.1109/.2005.1467103Ramachandran, C., Misra, S., & Obaidat, M. S. (2008). A probabilistic zonal approach for swarm-inspired wildfire detection using sensor networks. International Journal of Communication Systems, 21(10), 1047-1073. doi:10.1002/dac.937Misra, S., Singh, S., Khatua, M., & Obaidat, M. S. (2013). Extracting mobility pattern from target trajectory in wireless sensor networks. International Journal of Communication Systems, 28(2), 213-230. doi:10.1002/dac.2649Heinzelman, W. B., Chandrakasan, A. P., & Balakrishnan, H. (2002). An application-specific protocol architecture for wireless microsensor networks. IEEE Transactions on Wireless Communications, 1(4), 660-670. doi:10.1109/twc.2002.804190Younis, O., & Fahmy, S. (s. f.). Distributed clustering in ad-hoc sensor networks: a hybrid, energy-efficient approach. IEEE INFOCOM 2004. doi:10.1109/infcom.2004.1354534Manjeshwar, A., & Agrawal, D. P. (s. f.). TEEN: a routing protocol for enhanced efficiency in wireless sensor networks. Proceedings 15th International Parallel and Distributed Processing Symposium. IPDPS 2001. doi:10.1109/ipdps.2001.925197Manjeshwar, A., & Agrawal, D. P. (2002). APTEEN: a hybrid protocol for efficient routing and comprehensive information retrieval in wireless. Proceedings 16th International Parallel and Distributed Processing Symposium. doi:10.1109/ipdps.2002.1016600Sharif, A., Potdar, V., & Rathnayaka, A. J. D. (2010). Prioritizing Information for Achieving QoS Control in WSN. 2010 24th IEEE International Conference on Advanced Information Networking and Applications. doi:10.1109/aina.2010.166Alappat, V. J., Khanna, N., & Krishna, A. K. (2011). Advanced Sensor MAC protocol to support applications having different priority levels in Wireless Sensor Networks. 2011 6th International ICST Conference on Communications and Networking in China (CHINACOM). doi:10.1109/chinacom.2011.6158175Alam, K. M., Kamruzzaman, J., Karmakar, G., & Murshed, M. (2012). Priority Sensitive Event Detection in Hybrid Wireless Sensor Networks. 2012 21st International Conference on Computer Communications and Networks (ICCCN). doi:10.1109/icccn.2012.6289220Raja, A., & Su, X. (2008). A Mobility Adaptive Hybrid Protocol for Wireless Sensor Networks. 2008 5th IEEE Consumer Communications and Networking Conference. doi:10.1109/ccnc08.2007.159Srikanth, B., Harish, M., & Bhattacharjee, R. (2011). An energy efficient hybrid MAC protocol for WSN containing mobile nodes. 2011 8th International Conference on Information, Communications & Signal Processing. doi:10.1109/icics.2011.6173629Lee, Y.-D., Jeong, D.-U., & Lee, H.-J. (2011). Empirical analysis of the reliability of low-rate wireless u-healthcare monitoring applications. International Journal of Communication Systems, 26(4), 505-514. doi:10.1002/dac.1360Deepak, K. S., & Babu, A. V. (2013). Improving energy efficiency of incremental relay based cooperative communications in wireless body area networks. International Journal of Communication Systems, 28(1), 91-111. doi:10.1002/dac.2641Yuan Li, Wei Ye, & Heidemann, J. (s. f.). Energy and latency control in low duty cycle MAC protocols. IEEE Wireless Communications and Networking Conference, 2005. doi:10.1109/wcnc.2005.1424589Bianchi, G. (2000). Performance analysis of the IEEE 802.11 distributed coordination function. IEEE Journal on Selected Areas in Communications, 18(3), 535-547. doi:10.1109/49.840210Wei Ye, Heidemann, J., & Estrin, D. (s. f.). An energy-efficient MAC protocol for wireless sensor networks. Proceedings.Twenty-First Annual Joint Conference of the IEEE Computer and Communications Societies. doi:10.1109/infcom.2002.101940

Axillary node metastasis from differentiated thyroid carcinoma with hürthle and signet ring cell differentiation. A case of disseminated thyroid cancer with peculiar histologic findings

<p>Abstract</p> <p>Background</p> <p>Differentiated thyroid cancer is usually associated with an excellent prognosis and indolent course. Distant metastases are rare events at the onset of thyroid cancer. Among these presentations, metastasis to the axillary lymph nodes is even more unusual: only few cases were previously reported in the literature; there has been no report of axillary lymph node metastasis from follicular thyroid carcinoma. Axillary lymph node metastasis generally arises in the context of disseminated disease and carries an ominous prognosis.</p> <p>Case presentation</p> <p>Here we present a case of axillary lymph node metastasis in the context of disseminated differentiated thyroid cancer. The patient underwent near total thyroidectomy and neck and axillary lymph node dissection. A histopathological diagnosis of poorly differentiated follicular carcinoma with "signet ring cells" and Hürthle cell features was established. The patient received radioactive iodine therapy and TSH suppression therapy. Subsequently his serum thyroglobulin level decreased to 44.000 ng/ml from over 100.000 ng/ml.</p> <p>Discussion and Conclusion</p> <p>Currently there are only few reported cases of axillary node metastases from thyroid cancer, and to our knowledge, this is the first report on axillary lymph node metastasis from follicular thyroid carcinoma. "Signet ring cell" is a morphologic feature shared by both benign and, more rarely, malignant follicular thyroid neoplasm, and it generally correlates with an arrest in folliculogenesis. Our case is one of the rare "signet ring cells" carcinomas so far described.</p

Aligned nanofibres made of poly(3-hydroxybutyrate) grafted to hyaluronan for potential healthcare applications

In this work, a hybrid copolymer consisting of poly(3-hydroxybutyrate) grafted to hyaluronic acid (HA) was synthesised and characterised. Once formed, the P(3HB)-g-HA copolymer was soluble in water allowing a green electrospinning process. The diameters of nanofibres can be tailored by simply varying the Mw of polymer. The optimization of the process allowed to produce fibres of average diameter in the range of 100-150 nm and low polydispersity. The hydrophobic modification has not only increased the fibre diameter, but also the obtained layers were homogenous. At the nanoscale, the hybrid copolymer exhibited an unusual hairy topography. Moreover, the hardness and tensile properties of the hybrid were found to be superior compared to fibres made of unmodified HA. Particularly, this reinforcement was achieved at the longitudinal direction. Additionally, this work reports the use in the composition of a water-soluble copolymer containing photo cross-linkable moieties to produce insoluble materials post-electrospinning. The derivatives as well as their nanofibrous mats retain the biocompatibility of the natural polymers used for the fabrication

Shape of the oxygen abundance profiles in CALIFA face-on spiral galaxies

Astronomy & Astrophysics 587 (2016): A70 reproduced with permission from Astronomy & AstrophysicsWe measured the gas abundance profiles in a sample of 122 face-on spiral galaxies observed by the CALIFA survey and included all spaxels whose line emission was consistent with star formation. This type of analysis allowed us to improve the statistics with respect to previous studies, and to properly estimate the oxygen distribution across the entire disc to a distance of up to 3-4 disc effective radii (re). We confirm the results obtained from classical H ii region analysis. In addition to the general negative gradient, an outer flattening can be observed in the oxygen abundance radial profile. An inner drop is also found in some cases. There is a common abundance gradient between 0.5 and 2.0 re of αO/H =-0.075 dex/re with a scatter of σ = 0.016 dex/re when normalising the distances to the disc effective radius. By performing a set of Kolmogorov-Smirnov tests, we determined that this slope is independent of other galaxy properties, such as morphology, absolute magnitude, and the presence or absence of bars. In particular, barred galaxies do not seem to display shallower gradients, as predicted by numerical simulations. Interestingly, we find that most of thegalaxies in the sample with reliable oxygen abundance values beyond ~2 effective radii (57 galaxies) present a flattening of the abundance gradient in these outer regions. This flattening is not associated with any morphological feature, which suggests that it is a common property of disc galaxies. Finally, we detect a drop or truncation of the abundance in the inner regions of 27 galaxies in the sample; this is only visible for the most massive galaxiesWe acknowledge financial support from the Spanish Ministerio de Economía y Competitividad (MINECO) via grant AYA2012-31935, and from the “Junta de Andalucía” local government through the FQM-108 project. We also acknowledge support to the ConaCyt funding program 180125. Y.A. acknowledges fi- nantial support from the Ramón y Cajal programme (RyC-2011-09461). Y.A. and A.I.D. acknowledge support from the project AYA2013-47742-C4-3-P from the Spanish MINECO, as well as the “Study of Emission-Line Galaxies with Integral-Field Spectroscopy” (SELGIFS) programme, funded by the EU (FP7- PEOPLE-2013-IRSES-612701). Support for L.G. is provided by the Ministry of Economy, Development, and Tourism’s Millennium Science Initiative through grant IC120009, awarded to The Millennium Institute of Astrophysics, MAS. LG acknowledges support by CONICYT through FONDECYT grant 3140566. R.M.G.D. acknowledges support from the Spanish grant AYA2014-57490-P, and from the “Junta de Andalucía” P12-FQM2828 project. RAM thanks the Spanish program of International Campus of Excellence Moncloa (CEI). IM and A.d.O. acknowledge support from the Spanish MINECO grant AYA2013-42227P. JMA acknowledges support from the European Research Council Starting Grant (SEDmorph, P.I. V. Wild). Support for MM has been provided by DGICYT grant AYA2013-47742-C4-4-P. PSB acknowledges support from the Ramón y Cajal programme, grant ATA2010-21322-C03-02 from the Spanish MINECO. CJW acknowledges support through the Marie Curie Career Grant Integration 30391

A free weekly iron-folic acid supplementation and regular deworming program is associated with improved hemoglobin and iron status indicators in Vietnamese women

Background Anemia due to iron deficiency is recognized as one of the major nutritional deficiencies in women and children in developing countries. Daily iron supplementation for pregnant women is recommended in many countries although there are few reports of these programs working efficiently or effectively. Weekly iron-folic acid supplementation (WIFS) and regular deworming treatment is recommended for non-pregnant women living in areas with high rates of anemia. Following a baseline survey to assess the prevalence of anemia, iron deficiency and soil transmitted helminth infections, we implemented a program to make WIFS and regular deworming treatment freely and universally available for all women of reproductive age in two districts of a province in northern Vietnam over a 12 month period. The impact of the program at the population level was assessed in terms of: i) change in mean hemoglobin and iron status indicators, and ii) change in the prevalence of anemia, iron deficiency and hookworm infections. Method Distribution of WIFS and deworming were integrated with routine health services and made available to 52,000 women. Demographic data and blood and stool samples were collected in baseline, and three and 12-month post-implementation surveys using a population-based, stratified multi-stage cluster sampling design. Results The mean Hb increased by 9.6 g/L (95% CI, 5.7, 13.5, p < 0.001) during the study period. Anemia (Hb<120 g/L) was present in 131/349 (37.5%, 95% CI 31.3, 44.8) subjects at baseline, and in 70/363 (19.3%, 95% CI 14.0, 24.6) after twelve months. Iron deficiency reduced from 75/329 (22.8%, 95% CI 16.9, 28.6) to 33/353 (9.3%, 95% CI 5.7, 13.0) by the 12-mnth survey, and hookworm infection from 279/366 (76.2%,, 95% CI 68.6, 83.8) to 66/287 (23.0%, 95% CI 17.5, 28.5) over the same period. Conclusion A free, universal WIFS program with regular deworming was associated with reduced prevalence and severity of anemia, iron deficiency and h