835 research outputs found
Multilevel intellectual approach to HTTP-requests legitimacy validation
In the paper a multilevel intellectual approach to HTTP-requests legitimacy validation is proposed. The approach is devised for HTTP-flood DDoS-attacks detection and prevention in telecommunication networks with a web-server as the target attack object. The analysis of HTTP-requests attributes and their signatures is provided. On the basis of the analysis the attributes are separated into several levels that allow us to design a flow analyzer in a form of the multilevel block. Due to a multilevel structure of the flow analyzer a minimization of resources, spent for a request handling, is achieved
Stress-strain state of the mine massif around the chambers of the second stage of mining
A stress-strain state of the rock mass around the chambers of the second stage of mining was analyzed with the help of thermodynamic method. This study is the question of the day as the ore reserves in the chambers of the second stage of mining are, as a rule, extracted being surrounded by the filling mass, and due to this the highest rates of the ore losses and contamination with the filling mass are observed. In connection with this, the study of the stress-strained state of the filling mass and establishment of a method for improving the massif stability presents a great interest today. A calculation scheme for modeling thermodynamic processes in the rock mass around the chambers was developed with the purpose to study the stress field and determine principles of radial stress changing in the filling mass of the surrounding chamber. A chamber in the layer at the depth of 740-840 m was simulated with the following average geotechnical conditions: depth of the extraction chamber, angle of the deposit depression, horizontal thickness of deposit, rock strength in the hanging layer against uniaxial compression, rock strength in the bottom layer against uniaxial compression, and stowing strength against uniaxial compression. The study determined areas with tensile stress in the rocks of the bottom layer, ore mass and filling mass, and their parameters (size, maximum tension) and formulated empirical equations for the dependences between radial tensions and distance to the chambers L of the second stage of mining. The areas of destructive deformation and their dimensions in the stowing mass around the chambers of the second stage of mining at the level 740-840 m were established. Maximum values are defined for the stresses acting in the stowing mass which, exceeding the ultimate strength, cause the mass failure into the space of the chamber of the second stage. In order to prevent the stowing mass failure it is recommended to make a consolidating layer of the solid stowing at the 2/3 height of the chamber in order to resist the high tensile stresses and to ensure the mass stability
Complex application of certain micronatrients in men with androgen deficiency and pathosprimes
A complex approach was made for the deactivation of deuterine micronutrients, which include antioxidant and metabolic metabolism, in individuals with androgen deficiency and idiopathic pathospermia. It has been shown that is using the complex preparation Β«FEROLLΒ» for 60 days leads to increase the parameters of the spermogram to normal values on the background of normal androgen levels of blood in these patients
Numerical modelling of massif zonal structuring around underground working
Purpose. To identify indicators of massif zonal structuring around underground working using numerical modeling techniques.
Methods. Research into massif zonal structuring was performed using finite element method and thermodynamic method by which the size and number of zones formed around development workings and stopes have been simulated.
Findings. The ratio of zonesβ vertical and horizontal semiaxes in the massif has been established and reliability of the obtained results was determined. The prospects of new modeling techniques for the study of massif zonal structuring parameters around underground workings have been identified.
Originality. The opportunities for wide application of numerical simulation methods to study the phenomenon of zonal encapsulation by the massif of underground workings have been revealed.
Practical implications. The sizes and shapes of zones in the massif around workings were determined and requirements were formulated stating that synergetic research methods should allow to more accurately determine the number, size and shape of zones, as well as fading sinusoidal stress and massif strain domains.Π¦Π΅Π»Ρ. ΠΡΡΠ²ΠΈΡΡ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ Π·ΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΡΡΠΊΡΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΌΠ°ΡΡΠΈΠ²Π° Π²ΠΎΠΊΡΡΠ³ ΠΏΠΎΠ΄Π·Π΅ΠΌΠ½ΡΡ
Π²ΡΡΠ°Π±ΠΎΡΠΎΠΊ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΠΈΡΠ»Π΅Π½Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ.
ΠΠ΅ΡΠΎΠ΄ΠΈΠΊΠ°. ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π·ΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΡΡΠΊΡΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΌΠ°ΡΡΠΈΠ²Π° Π²ΡΠΏΠΎΠ»Π½ΡΠ»ΠΎΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΠΊΠΎΠ½Π΅ΡΠ½ΡΡ
ΡΠ»Π΅ΠΌΠ΅Π½ΡΠΎΠ² ΠΈ ΡΠ΅ΡΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ, Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΊΠΎΡΠΎΡΡΡ
ΡΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½Ρ ΡΠ°Π·ΠΌΠ΅ΡΡ ΠΈ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ Π·ΠΎΠ½, ΡΠΎΡΠΌΠΈΡΡΡΡΠΈΡ
ΡΡ Π²ΠΎΠΊΡΡΠ³ ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΠΈ ΠΎΡΠΈΡΡΠ½ΡΡ
Π²ΡΡΠ°Π±ΠΎΡΠΎΠΊ.
Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ ΠΎΡΠ½ΠΎΡΠ΅Π½ΠΈΠ΅ Π²Π΅ΡΡΠΈΠΊΠ°Π»ΡΠ½ΡΡ
ΠΈ Π³ΠΎΡΠΈΠ·ΠΎΠ½ΡΠ°Π»ΡΠ½ΡΡ
ΠΏΠΎΠ»ΡΠΎΡΠ΅ΠΉ Π·ΠΎΠ½ Π² ΠΌΠ°ΡΡΠΈΠ²Π΅ ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π° Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎΡΡΡ ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΡ
ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ². Π Π°ΡΠΊΡΡΡΡ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²Ρ ΡΠΎΠ·Π΄Π°Π½ΠΈΡ Π½ΠΎΠ²ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π΄Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΠΎΠ² Π·ΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΡΡΠΊΡΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΌΠ°ΡΡΠΈΠ²Π° Π²ΠΎΠΊΡΡΠ³ ΠΏΠΎΠ΄Π·Π΅ΠΌΠ½ΡΡ
Π²ΡΡΠ°Π±ΠΎΡΠΎΠΊ.
ΠΠ°ΡΡΠ½Π°Ρ Π½ΠΎΠ²ΠΈΠ·Π½Π°. Π Π°ΡΠΊΡΡΡΡ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΠΈ ΡΠΈΡΠΎΠΊΠΎ ΠΏΡΠΈΠΌΠ΅Π½ΡΠ΅ΠΌΡΡ
ΡΠΈΡΠ»Π΅Π½Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΌΠΎΠ΄Π΅Π»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π΄Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΡΠ΅Π½ΠΎΠΌΠ΅Π½Π° Π·ΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°ΠΏΡΡΠ»ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΠΌΠ°ΡΡΠΈΠ²ΠΎΠΌ ΠΏΠΎΠ΄Π·Π΅ΠΌΠ½ΡΡ
Π²ΡΡΠ°Π±ΠΎΡΠΎΠΊ.
ΠΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠ°Ρ Π·Π½Π°ΡΠΈΠΌΠΎΡΡΡ. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Ρ ΡΠ°Π·ΠΌΠ΅ΡΡ ΠΈ ΡΠΎΡΠΌΠ° Π·ΠΎΠ½ Π² ΠΌΠ°ΡΡΠΈΠ²Π΅ Π²ΠΎΠΊΡΡΠ³ Π²ΡΡΠ°Π±ΠΎΡΠΎΠΊ ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΡΡΠ΅Π±ΠΎΠ²Π°Π½ΠΈΡ ΠΊ ΡΠΈΠ½Π΅ΡΠ³Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΌΠ΅ΡΠΎΠ΄Π°ΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ, Π·Π°ΠΊΠ»ΡΡΠ°ΡΡΠΈΠ΅ΡΡ Π² Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎΡΡΡΡ
Π±ΠΎΠ»Π΅Π΅ ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π°, ΡΠ°Π·ΠΌΠ΅ΡΠΎΠ² ΠΈ ΡΠΎΡΠΌΡ Π·ΠΎΠ½, Π° ΡΠ°ΠΊΠΆΠ΅ ΡΠΈΠ½ΡΡΠΎΠΈΠ΄Π°Π»ΡΠ½ΠΎ-Π·Π°ΡΡΡ
Π°ΡΡΠΈΡ
Π½Π°ΠΏΡΡΠΆΠ΅Π½ΠΈΠΉ ΠΈ ΠΊΠΎΠ»ΡΡΠ΅Π²ΡΡ
ΠΎΠ±Π»Π°ΡΡΠ΅ΠΉ Π΄Π΅ΡΠΎΡΠΌΠ°ΡΠΈΠΉ ΠΌΠ°ΡΡΠΈΠ²Π°.ΠΠ΅ΡΠ°. ΠΠΈΡΠ²ΠΈΡΠΈ ΠΏΠΎΠΊΠ°Π·Π½ΠΈΠΊΠΈ Π·ΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΡΡΠΊΡΡΡΡΠ²Π°Π½Π½Ρ ΠΌΠ°ΡΠΈΠ²Ρ Π½Π°Π²ΠΊΠΎΠ»ΠΎ ΠΏΡΠ΄Π·Π΅ΠΌΠ½ΠΈΡ
Π²ΠΈΡΠΎΠ±ΠΎΠΊ Π·Π° Π΄ΠΎΠΏΠΎΠΌΠΎΠ³ΠΎΡ ΡΠΈΡΠ΅Π»ΡΠ½ΠΈΡ
ΠΌΠ΅ΡΠΎΠ΄ΡΠ² ΠΌΠΎΠ΄Π΅Π»ΡΠ²Π°Π½Π½Ρ.
ΠΠ΅ΡΠΎΠ΄ΠΈΠΊΠ°. ΠΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ Π·ΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΡΡΠΊΡΡΡΡΠ²Π°Π½Π½Ρ ΠΌΠ°ΡΠΈΠ²Ρ Π²ΠΈΠΊΠΎΠ½ΡΠ²Π°Π»ΠΎΡΡ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ ΠΊΡΠ½ΡΠ΅Π²ΠΈΡ
Π΅Π»Π΅ΠΌΠ΅Π½ΡΡΠ² Ρ ΡΠ΅ΡΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΡΡΠ½ΠΈΠΌ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠΌ, Π·Π° Π΄ΠΎΠΏΠΎΠΌΠΎΠ³ΠΎΡ ΡΠΊΠΈΡ
Π·ΠΌΠΎΠ΄Π΅Π»ΡΠΎΠ²Π°Π½Ρ ΡΠΎΠ·ΠΌΡΡΠΈ ΡΠ° ΠΊΡΠ»ΡΠΊΡΡΡΡ Π·ΠΎΠ½, ΡΠΊΡ ΡΠΎΡΠΌΡΡΡΡΡΡ Π½Π°Π²ΠΊΠΎΠ»ΠΎ ΠΏΡΠ΄Π³ΠΎΡΠΎΠ²ΡΠΈΡ
ΠΉ ΠΎΡΠΈΡΠ½ΠΈΡ
Π²ΠΈΡΠΎΠ±ΠΎΠΊ.
Π Π΅Π·ΡΠ»ΡΡΠ°ΡΠΈ. ΠΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ Π²ΡΠ΄Π½ΠΎΡΠ΅Π½Π½Ρ Π²Π΅ΡΡΠΈΠΊΠ°Π»ΡΠ½ΠΈΡ
Ρ Π³ΠΎΡΠΈΠ·ΠΎΠ½ΡΠ°Π»ΡΠ½ΠΈΡ
Π½Π°ΠΏΡΠ²Π²ΡΡΠ΅ΠΉ Π·ΠΎΠ½ Ρ ΠΌΠ°ΡΠΈΠ²Ρ ΡΠ° Π²ΠΈΠ·Π½Π°ΡΠ΅Π½Π° Π΄ΠΎΡΡΠΎΠ²ΡΡΠ½ΡΡΡΡ ΠΎΡΡΠΈΠΌΠ°Π½ΠΈΡ
ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡΠ². Π ΠΎΠ·ΠΊΡΠΈΡΠΎ ΠΏΠ΅ΡΡΠΏΠ΅ΠΊΡΠΈΠ²ΠΈ ΡΡΠ²ΠΎΡΠ΅Π½Π½Ρ Π½ΠΎΠ²ΠΈΡ
ΠΌΠ΅ΡΠΎΠ΄ΡΠ² ΠΌΠΎΠ΄Π΅Π»ΡΠ²Π°Π½Π½Ρ Π΄Π»Ρ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ ΠΏΠ°ΡΠ°ΠΌΠ΅ΡΡΡΠ² Π·ΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΡΡΠΊΡΡΡΡΠ²Π°Π½Π½Ρ ΠΌΠ°ΡΠΈΠ²Ρ Π½Π°Π²ΠΊΠΎΠ»ΠΎ ΠΏΡΠ΄Π·Π΅ΠΌΠ½ΠΈΡ
Π²ΠΈΡΠΎΠ±ΠΎΠΊ.
ΠΠ°ΡΠΊΠΎΠ²Π° Π½ΠΎΠ²ΠΈΠ·Π½Π°. Π ΠΎΠ·ΠΊΡΠΈΡΠΎ ΠΌΠΎΠΆΠ»ΠΈΠ²ΠΎΡΡΡ ΡΠΈΡΠΎΠΊΠΎ Π·Π°ΡΡΠΎΡΠΎΠ²Π°Π½ΠΈΡ
ΡΠΈΡΠ΅Π»ΡΠ½ΠΈΡ
ΠΌΠ΅ΡΠΎΠ΄ΡΠ² ΠΌΠΎΠ΄Π΅Π»ΡΠ²Π°Π½Π½Ρ Π΄Π»Ρ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ ΡΠ΅Π½ΠΎΠΌΠ΅Π½Π° Π·ΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΠ°ΠΏΡΡΠ»ΡΠ²Π°Π½Π½Ρ ΠΌΠ°ΡΠΈΠ²ΠΎΠΌ ΠΏΡΠ΄Π·Π΅ΠΌΠ½ΠΈΡ
Π²ΠΈΡΠΎΠ±ΠΎΠΊ.
ΠΡΠ°ΠΊΡΠΈΡΠ½Π° Π·Π½Π°ΡΠΈΠΌΡΡΡΡ. ΠΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ ΡΠΎΠ·ΠΌΡΡΠΈ Ρ ΡΠΎΡΠΌΡ Π·ΠΎΠ½ Ρ ΠΌΠ°ΡΠΈΠ²Ρ Π½Π°Π²ΠΊΠΎΠ»ΠΎ Π²ΠΈΡΠΎΠ±ΠΎΠΊ ΡΠ° Π²ΠΈΠ·Π½Π°ΡΠ΅Π½ΠΎ Π²ΠΈΠΌΠΎΠ³ΠΈ Π΄ΠΎ ΡΠΈΠ½Π΅ΡΠ³Π΅ΡΠΈΡΠ½ΠΈΡ
ΠΌΠ΅ΡΠΎΠ΄ΡΠ² Π΄ΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ, ΡΠΎ ΠΏΠΎΠ»ΡΠ³Π°ΡΡΡ Ρ ΠΌΠΎΠΆΠ»ΠΈΠ²ΠΎΡΡΡ Π±ΡΠ»ΡΡ ΡΠΎΡΠ½ΠΎΠ³ΠΎ Π²ΠΈΠ·Π½Π°ΡΠ΅Π½Π½Ρ ΠΊΡΠ»ΡΠΊΠΎΡΡΡ, ΡΠΎΠ·ΠΌΡΡΡΠ² Ρ ΡΠΎΡΠΌΠΈ Π·ΠΎΠ½, Π° ΡΠ°ΠΊΠΎΠΆ ΡΠΈΠ½ΡΡΠΎΡΠ΄Π°Π»ΡΠ½ΠΎ-Π·Π³Π°ΡΠ°ΡΡΠΈΡ
Π½Π°ΠΏΡΡΠΆΠ΅Π½Ρ ΡΠ° ΠΊΡΠ»ΡΡΠ΅Π²ΠΈΡ
ΠΎΠ±Π»Π°ΡΡΠ΅ΠΉ Π΄Π΅ΡΠΎΡΠΌΠ°ΡΡΠΉ ΠΌΠ°ΡΠΈΠ²Ρ.ΠΠ° ΠΏΡΠ΅Π΄ΠΎΡΡΠ°Π²Π»Π΅Π½Π½ΡΠ΅ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΎΠΊΠ°Π·Π°Π½Π½ΡΡ ΠΏΠΎΠ΄Π΄Π΅ΡΠΆΠΊΡ ΠΏΡΠΈ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠΈ ΡΠ΅ΠΎΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΡΠ΅ΡΠΌΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° Π°Π²ΡΠΎΡΡ Π²ΡΡΠ°ΠΆΠ°ΡΡ Π±Π»Π°Π³ΠΎΠ΄Π°ΡΠ½ΠΎΡΡΡ Π·Π°Π²Π΅Π΄ΡΡΡΠ΅ΠΌΡ ΠΊΠ°ΡΠ΅Π΄ΡΡ ΠΏΠΎΠ΄Π·Π΅ΠΌΠ½ΠΎΠΉ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠΈ ΠΌΠ΅ΡΡΠΎΡΠΎΠΆΠ΄Π΅Π½ΠΈΠΉ ΠΏΠΎΠ»Π΅Π·Π½ΡΡ
ΠΈΡΠΊΠΎΠΏΠ°Π΅ΠΌΡΡ
ΠΠΎΡΡΠ΄Π°ΡΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΠ£Π βΠΡΠΈΠ²ΠΎΡΠΎΠΆΡΠΊΠΈΠΉ Π½Π°ΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΠΉ ΡΠ½ΠΈΠ²Π΅ΡΡΠΈΡΠ΅Ρβ Π.Π. ΠΠ°Π»ΠΈΠ½ΠΈΡΠ΅Π½ΠΊΡ
TO THE QUESTION OF THE VOLTAGE STABILITY ENSURING FOR COMPLEX MONITORING SYSTEMS OF METALβS STATUS
The paper considers one of the tasks that need to be solved when developing complex monitoring systems of metalβs status, which is to ensure the stability of the supply voltage, and the results of compensatory voltage stabilizer development are given. The analysis results of the adopted circuit solutions correctness are shown and the conformity of the stabilized power supply parameters to the given conditions is proved.The paper considers one of the tasks that need to be solved when developing complex monitoring systems of metalβs status, which is to ensure the stability of the supply voltage, and the results of compensatory voltage stabilizer development are given. The analysis results of the adopted circuit solutions correctness are shown and the conformity of the stabilized power supply parameters to the given conditions is proved
ΠΠΎΡΠ»ΡΠ΄ΠΆΠ΅Π½Π½Ρ Π²ΠΏΠ»ΠΈΠ²Ρ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠ±ΡΠ½ΠΎΠ²Π°Π½ΠΎΠ³ΠΎ ΠΊΡΠ΅ΠΌΡ ΠΠ΅ΡΠΌΠ°Π»ΡΠΏΠΎΡΠ½ Π½Π° ΠΏΡΠΎΠ½ΠΈΠΊΠ½ΡΡΡΡ ΡΡΠ΄ΠΈΠ½Π½ΠΎΡ ΡΡΡΠ½ΠΊΠΈ
Topicality. The problem of treating wounds, including burns, remains relevant in modern medicine. For today in the arsenal of doctors there is a wide choice of medicines for treatment of wound process, however none of them is universal, and their effects are far from optimal. This makes it necessary to search for and develop new drugs for pharmacotherapy of the wound process.Aim. To study the capillary-firming activity of new cream on the model of increased permeability of the vessels of the abdominal wall in rats caused by various phlogogens.Materials and methods. With the purpose of in-depth study of the effect of the cream on the exudative component of the inflammatory reaction, experiments were conducted to determine its effect on the permeability of the vessels of the abdominal wall, which was caused by the administration of solutions of histamine, formalin, carrageenan, egg protein. By the difference in time of staining of the papules, after the introduction of the dye, the conclusion was made about the effect of the cream on vascular permeability.Results and discussion. The presence of new vascular stabilizing action in the new combined cream has been established due to the stabilization of the cell membranes and suppression of the activity of the inflammatory mediators that are formed as a result of cyclo- and lipoxygenase metabolism of arachidonic acid and, thereby, reduce the permeability of the vascular wall, which is an important component of the pharmacodynamics of the investigational pharmacological preparation, which is proposed for inflammatory-destructive processes.Conclusions. The ability of the test cream to reduce vascular permeability when introducing various phlogogenic substances indicates a multicomponent anti-inflammatory effect, which is associated with the antioxidant and membrane-stabilizing properties of the active substances of the cream.ΠΠΊΡΡΠ°Π»ΡΠ½ΠΎΡΡΡ. ΠΡΠΎΠ±Π»Π΅ΠΌΠ° Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΠ°Π½, Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ ΠΎΠΆΠΎΠ³ΠΎΠ²ΡΡ
, ΠΎΡΡΠ°Π΅ΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΠΉ Π² ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Π΅. ΠΠ° ΡΠ΅Π³ΠΎΠ΄Π½ΡΡΠ½ΠΈΠΉ Π΄Π΅Π½Ρ Π² Π°ΡΡΠ΅Π½Π°Π»Π΅ Π²ΡΠ°ΡΠ΅ΠΉ Π΅ΡΡΡ Π±ΠΎΠ»ΡΡΠΎΠΉ Π²ΡΠ±ΠΎΡ Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ² Π΄Π»Ρ Π»Π΅ΡΠ΅Π½ΠΈΡ ΡΠ°Π½Π΅Π²ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ°, ΠΎΠ΄Π½Π°ΠΊΠΎ Π½ΠΈ ΠΎΠ΄ΠΈΠ½ ΠΈΠ· Π½ΠΈΡ
Π½Π΅ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠ½ΠΈΠ²Π΅ΡΡΠ°Π»ΡΠ½ΡΠΌ, Π° ΠΈΡ
ΡΡΡΠ΅ΠΊΡΡ Π΄Π°Π»Π΅ΠΊΠΈ ΠΎΡ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΡΡ
. ΠΡΠΎ ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»ΠΈΠ²Π°Π΅Ρ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΡ ΠΏΠΎΠΈΡΠΊΠ° ΠΈ ΡΠ°Π·ΡΠ°Π±ΠΎΡΠΊΠΈ Π½ΠΎΠ²ΡΡ
Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΡΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ² Π΄Π»Ρ ΡΠ°ΡΠΌΠ°ΠΊΠΎΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΡΠ°Π½Π΅Π²ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ°.Π¦Π΅Π»Ρ ΡΠ°Π±ΠΎΡΡ Π·Π°ΠΊΠ»ΡΡΠ°Π»Π°ΡΡ Π² ΠΈΠ·ΡΡΠ΅Π½ΠΈΠΈ ΠΊΠ°ΠΏΠΈΠ»Π»ΡΡΠΎΡΠΊΡΠ΅ΠΏΠ»ΡΡΡΠ΅ΠΉ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΡΠ΅ΠΌΠ° Π½Π° ΠΌΠΎΠ΄Π΅Π»ΠΈ ΠΏΠΎΠ²ΡΡΠ΅Π½Π½ΠΎΠΉ ΠΏΡΠΎΠ½ΠΈΡΠ°Π΅ΠΌΠΎΡΡΠΈ ΡΠΎΡΡΠ΄ΠΎΠ² Π±ΡΡΡΠ½ΠΎΠΉ ΡΡΠ΅Π½ΠΊΠΈ Ρ ΠΊΡΡΡ, Π²ΡΠ·Π²Π°Π½Π½ΠΎΠΉ ΡΠ°Π·Π»ΠΈΡΠ½ΡΠΌΠΈ ΡΠ»ΠΎΠ³ΠΎΠ³Π΅Π½Π°ΠΌΠΈ.ΠΠ°ΡΠ΅ΡΠΈΠ°Π»Ρ ΠΈ ΠΌΠ΅ΡΠΎΠ΄Ρ. Π‘ ΡΠ΅Π»ΡΡ ΡΠ³Π»ΡΠ±Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ Π²Π»ΠΈΡΠ½ΠΈΡ ΠΊΡΠ΅ΠΌΠ° Π½Π° ΡΠΊΡΡΡΠ΄Π°ΡΠΈΠ²Π½ΡΠΉ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½Ρ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π°ΠΊΡΠΈΠΈ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ ΡΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΡ ΠΏΠΎ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ Π΅Π³ΠΎ Π²Π»ΠΈΡΠ½ΠΈΡ Π½Π° ΠΏΡΠΎΠ½ΠΈΡΠ°Π΅ΠΌΠΎΡΡΡ ΡΠΎΡΡΠ΄ΠΎΠ² Π±ΡΡΡΠ½ΠΎΠΉ ΡΡΠ΅Π½ΠΊΠΈ, ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ ΠΊΠΎΡΠΎΡΠΎΠΉ Π²ΡΠ·ΡΠ²Π°Π»ΠΈ Π²Π²Π΅Π΄Π΅Π½ΠΈΠ΅ΠΌ ΡΠ°ΡΡΠ²ΠΎΡΠΎΠ² Π³ΠΈΡΡΠ°ΠΌΠΈΠ½Π°, ΡΠΎΡΠΌΠ°Π»ΠΈΠ½Π°, ΠΊΠ°ΡΠ°Π³Π΅Π½ΠΈΠ½Π°, ΡΠΈΡΠ½ΠΎΠ³ΠΎ Π±Π΅Π»ΠΊΠ°. ΠΠΎ ΡΠ°Π·Π½ΠΈΡΠ΅ Π²ΠΎ Π²ΡΠ΅ΠΌΠ΅Π½ΠΈ ΠΎΠΊΡΠ°ΡΠΈΠ²Π°Π½ΠΈΡ ΠΏΠ°ΠΏΡΠ» ΠΏΠΎΡΠ»Π΅ Π²Π²Π΅Π΄Π΅Π½ΠΈΡ ΠΊΡΠ°ΡΠΈΡΠ΅Π»Ρ Π΄Π΅Π»Π°Π»ΠΈ Π²ΡΠ²ΠΎΠ΄ ΠΎ Π²Π»ΠΈΡΠ½ΠΈΠΈ ΠΊΡΠ΅ΠΌΠ° Π½Π° ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ ΠΏΡΠΎΠ½ΠΈΡΠ°Π΅ΠΌΠΎΡΡΡ.Π Π΅Π·ΡΠ»ΡΡΠ°ΡΡ ΠΈ ΠΈΡ
ΠΎΠ±ΡΡΠΆΠ΄Π΅Π½ΠΈΠ΅. Π£ΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ΠΎ Π½Π°Π»ΠΈΡΠΈΠ΅ Ρ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ ΠΊΡΠ΅ΠΌΠ° ΡΠΎΡΡΠ΄ΠΈΡΡΠΎΡΡΠ°Π±ΠΈΠ»ΠΈΠ·ΠΈΡΡΡΡΠ΅Π³ΠΎ Π΄Π΅ΠΉΡΡΠ²ΠΈΡ Π·Π° ΡΡΠ΅Ρ ΡΡΠ°Π±ΠΈΠ»ΠΈΠ·Π°ΡΠΈΠΈ ΠΌΠ΅ΠΌΠ±ΡΠ°Π½Ρ ΠΊΠ»Π΅ΡΠΎΠΊ ΠΈ ΠΏΠΎΠ΄Π°Π²Π»Π΅Π½ΠΈΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΠΈ ΠΌΠ΅Π΄ΠΈΠ°ΡΠΎΡΠΎΠ² Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΡ, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΎΠ±ΡΠ°Π·ΡΡΡΡΡ Π² ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΠΈΠΊΠ»ΠΎ- ΠΈ Π»ΠΈΠΏΠΎΠΎΠΊΡΠΈΠ³Π΅Π½Π°Π·Π½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΠΈΠ·ΠΌΠ° Π°ΡΠ°Ρ
ΠΈΠ΄ΠΎΠ½ΠΎΠ²ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΡ ΠΈ Π±Π»Π°Π³ΠΎΠ΄Π°ΡΡ ΡΡΠΎΠΌΡ ΡΠ½ΠΈΠΆΠ°ΡΡ ΠΏΡΠΎΠ½ΠΈΡΠ°Π΅ΠΌΠΎΡΡΡ ΡΠΎΡΡΠ΄ΠΈΡΡΠΎΠΉ ΡΡΠ΅Π½ΠΊΠΈ, ΡΡΠΎ ΡΠ²Π»ΡΠ΅ΡΡΡ Π²Π°ΠΆΠ½ΠΎΠΉ ΡΠΎΡΡΠ°Π²Π»ΡΡΡΠ΅ΠΉ ΡΠ°ΡΠΌΠ°ΠΊΠΎΠ΄ΠΈΠ½Π°ΠΌΠΈΠΊΠΈ ΠΈΡΡΠ»Π΅Π΄ΡΠ΅ΠΌΠΎΠ³ΠΎ ΡΠ°ΡΠΌΠ°ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠ° ΠΊΠ°ΠΊ ΡΡΠ΅Π΄ΡΡΠ²Π°, ΠΊΠΎΡΠΎΡΡΠΉ ΠΏΡΠ΅Π΄Π»Π°Π³Π°Π΅ΡΡΡ ΠΏΡΠΈ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎ-Π΄Π΅ΡΡΡΡΠΊΡΠΈΠ²Π½ΡΡ
ΠΏΡΠΎΡΠ΅ΡΡΠ°Ρ
.ΠΡΠ²ΠΎΠ΄Ρ. Π‘ΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΡ ΠΈΡΡΠ»Π΅Π΄ΡΠ΅ΠΌΠΎΠ³ΠΎ ΠΊΡΠ΅ΠΌΠ° ΡΠΌΠ΅Π½ΡΡΠ°ΡΡ ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ ΠΏΡΠΎΠ½ΠΈΡΠ°Π΅ΠΌΠΎΡΡΡ ΠΏΡΠΈ Π²Π²Π΅Π΄Π΅Π½ΠΈΠΈ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
ΡΠ»ΠΎΠ³ΠΎΠ³Π΅Π½Π½ΡΡ
Π²Π΅ΡΠ΅ΡΡΠ² ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΡΠ΅Ρ ΠΎ ΠΌΠ½ΠΎΠ³ΠΎΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠ½ΠΎΠΌ ΠΏΡΠΎΡΠΈΠ²ΠΎΠ²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΌ Π΄Π΅ΠΉΡΡΠ²ΠΈΠΈ, ΠΊΠΎΡΠΎΡΠΎΠ΅ ΡΠ²ΡΠ·Π°Π½ΠΎ Ρ Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΡΠΌΠΈ ΠΈ ΠΌΠ΅ΠΌΠ±ΡΠ°Π½ΠΎΡΡΠ°Π±ΠΈΠ»ΠΈΠ·ΠΈΡΡΡΡΠΈΠΌΠΈ ΡΠ²ΠΎΠΉΡΡΠ²Π°ΠΌΠΈ Π΄Π΅ΠΉΡΡΠ²ΡΡΡΠΈΡ
Π²Π΅ΡΠ΅ΡΡΠ² ΠΊΡΠ΅ΠΌΠ°.ΠΠΊΡΡΠ°Π»ΡΠ½ΡΡΡΡ. ΠΡΠΎΠ±Π»Π΅ΠΌΠ° Π»ΡΠΊΡΠ²Π°Π½Π½Ρ ΡΠ°Π½, Π·ΠΎΠΊΡΠ΅ΠΌΠ° ΠΎΠΏΡΠΊΠΎΠ²ΠΈΡ
, Π·Π°Π»ΠΈΡΠ°ΡΡΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΡ Π² ΡΡΡΠ°ΡΠ½ΡΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Ρ. ΠΠ° ΡΠ΅ΠΏΠ΅ΡΡΡΠ½ΡΠΉ ΡΠ°Ρ Π² Π°ΡΡΠ΅Π½Π°Π»Ρ Π»ΡΠΊΠ°ΡΡΠ² Ρ Π²Π΅Π»ΠΈΠΊΠΈΠΉ Π²ΠΈΠ±ΡΡ Π»ΡΠΊΠ°ΡΡΡΠΊΠΈΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΡΠ² Π΄Π»Ρ Π»ΡΠΊΡΠ²Π°Π½Π½Ρ ΡΠ°Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡ, ΠΎΠ΄Π½Π°ΠΊ ΠΆΠΎΠ΄Π΅Π½ Π· Π½ΠΈΡ
Π½Π΅ Ρ ΡΠ½ΡΠ²Π΅ΡΡΠ°Π»ΡΠ½ΠΈΠΌ, Π° ΡΡ
Π΅ΡΠ΅ΠΊΡΠΈ Π΄Π°Π»Π΅ΠΊΡ Π²ΡΠ΄ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΈΡ
. Π¦Π΅ Π·ΡΠΌΠΎΠ²Π»ΡΡ Π½Π΅ΠΎΠ±Ρ
ΡΠ΄Π½ΡΡΡΡ ΠΏΠΎΡΡΠΊΡ Ρ ΡΠΎΠ·ΡΠΎΠ±ΠΊΠΈ Π½ΠΎΠ²ΠΈΡ
Π»ΡΠΊΠ°ΡΡΡΠΊΠΈΡ
ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΡΠ² Π΄Π»Ρ ΡΠ°ΡΠΌΠ°ΠΊΠΎΡΠ΅ΡΠ°ΠΏΡΡ ΡΠ°Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡ.ΠΠ΅ΡΠ° ΡΠΎΠ±ΠΎΡΠΈ ΠΏΠΎΠ»ΡΠ³Π°Π»Π° Ρ Π²ΠΈΠ²ΡΠ΅Π½Π½Ρ ΠΊΠ°ΠΏΡΠ»ΡΡΠΎΠ·ΠΌΡΡΠ½ΡΠ²Π°Π»ΡΠ½ΠΎΡ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΡΠ΅ΠΌΡ Π½Π° ΠΌΠΎΠ΄Π΅Π»Ρ ΠΏΡΠ΄Π²ΠΈΡΠ΅Π½ΠΎΡ ΠΏΡΠΎΠ½ΠΈΠΊΠ½ΠΎΡΡΡ ΡΡΠ΄ΠΈΠ½ ΡΠ΅ΡΠ΅Π²Π½ΠΎΡ ΡΡΡΠ½ΠΊΠΈ Ρ ΡΡΡΡΠ², Π²ΠΈΠΊΠ»ΠΈΠΊΠ°Π½ΠΎΡ ΡΡΠ·Π½ΠΈΠΌΠΈ ΡΠ»ΠΎΠ³ΠΎΠ³Π΅Π½Π°ΠΌΠΈ.ΠΠ°ΡΠ΅ΡΡΠ°Π»ΠΈ ΡΠ° ΠΌΠ΅ΡΠΎΠ΄ΠΈ. Π ΠΌΠ΅ΡΠΎΡ ΠΏΠΎΠ³Π»ΠΈΠ±Π»Π΅Π½ΠΎΠ³ΠΎ Π²ΠΈΠ²ΡΠ΅Π½Π½Ρ Π²ΠΏΠ»ΠΈΠ²Ρ ΠΊΡΠ΅ΠΌΡ Π½Π° Π΅ΠΊΡΡΠ΄Π°ΡΠΈΠ²Π½ΠΈΠΉ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½Ρ Π·Π°ΠΏΠ°Π»ΡΠ½ΠΎΡ ΡΠ΅Π°ΠΊΡΡΡ ΠΏΡΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ Π΅ΠΊΡΠΏΠ΅ΡΠΈΠΌΠ΅Π½ΡΠΈ Π· Π²ΠΈΠ·Π½Π°ΡΠ΅Π½Π½Ρ ΠΉΠΎΠ³ΠΎ Π²ΠΏΠ»ΠΈΠ²Ρ Π½Π° ΠΏΡΠΎΠ½ΠΈΠΊΠ½ΡΡΡΡ ΡΡΠ΄ΠΈΠ½ ΡΠ΅ΡΠ΅Π²Π½ΠΎΡ ΡΡΡΠ½ΠΊΠΈ, ΠΏΡΠ΄Π²ΠΈΡΠ΅Π½Π½Ρ ΡΠΊΠΎΡ Π²ΠΈΠΊΠ»ΠΈΠΊΠ°Π»ΠΈ Π²Π²Π΅Π΄Π΅Π½Π½ΡΠΌ ΡΠΎΠ·ΡΠΈΠ½ΡΠ² Π³ΡΡΡΠ°ΠΌΡΠ½Ρ, ΡΠΎΡΠΌΠ°Π»ΡΠ½Ρ, ΠΊΠ°ΡΠ°Π³Π΅Π½ΡΠ½Ρ, ΡΡΡΠ½ΠΎΠ³ΠΎ Π±ΡΠ»ΠΊΠ°. ΠΠ° ΡΡΠ·Π½ΠΈΡΠ΅Ρ Π² ΡΠ°ΡΡ ΠΏΡΠΎΡΠ°ΡΠ±ΠΎΠ²ΡΠ²Π°Π½Π½Ρ ΠΏΠ°ΠΏΡΠ» ΠΏΡΡΠ»Ρ Π²Π²Π΅Π΄Π΅Π½Π½Ρ Π±Π°ΡΠ²Π½ΠΈΠΊΠ° ΡΠΎΠ±ΠΈΠ»ΠΈ Π²ΠΈΡΠ½ΠΎΠ²ΠΎΠΊ ΠΏΡΠΎ Π²ΠΏΠ»ΠΈΠ² ΠΊΡΠ΅ΠΌΡ Π½Π° ΡΡΠ΄ΠΈΠ½Π½Ρ ΠΏΡΠΎΠ½ΠΈΠΊΠ½ΡΡΡΡ. Π Π΅Π·ΡΠ»ΡΡΠ°ΡΠΈ ΡΠ° ΡΡ
ΠΎΠ±Π³ΠΎΠ²ΠΎΡΠ΅Π½Π½Ρ. ΠΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Π° Π½Π°ΡΠ²Π½ΡΡΡΡ Ρ Π½ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΠΎΠΌΠ±ΡΠ½ΠΎΠ²Π°Π½ΠΎΠ³ΠΎ ΠΊΡΠ΅ΠΌΡ ΡΡΠ΄ΠΈΠ½ΠΎΡΡΠ°Π±ΡΠ»ΡΠ·ΡΠ²Π°Π»ΡΠ½ΠΎΡ Π΄ΡΡ Π·Π° ΡΠ°Ρ
ΡΠ½ΠΎΠΊ ΡΡΠ°Π±ΡΠ»ΡΠ·Π°ΡΡΡ ΠΌΠ΅ΠΌΠ±ΡΠ°Π½ΠΈ ΠΊΠ»ΡΡΠΈΠ½ ΡΠ° ΠΏΡΠΈΠ³Π½ΡΡΠ΅Π½Π½Ρ Π°ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΠΌΠ΅Π΄ΡΠ°ΡΠΎΡΡΠ² Π·Π°ΠΏΠ°Π»Π΅Π½Π½Ρ, ΡΠΎ ΡΡΠ²ΠΎΡΡΡΡΡΡΡ Π²Π½Π°ΡΠ»ΡΠ΄ΠΎΠΊ ΡΠΈΠΊΠ»ΠΎ- ΡΠ° Π»ΡΠΏΠΎΠΎΠΊΡΠΈΠ³Π΅Π½Π°Π·Π½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠ°Π±ΠΎΠ»ΡΠ·ΠΌΡ Π°ΡΠ°Ρ
ΡΠ΄ΠΎΠ½ΠΎΠ²ΠΎΡ ΠΊΠΈΡΠ»ΠΎΡΠΈ ΡΠ° Π·Π°Π²Π΄ΡΠΊΠΈ ΡΡΠΎΠΌΡ Π·Π½ΠΈΠΆΡΠ²Π°ΡΠΈ ΠΏΡΠΎΠ½ΠΈΠΊΠ½ΡΡΡΡ ΡΡΠ΄ΠΈΠ½Π½ΠΎΡ ΡΡΡΠ½ΠΊΠΈ, ΡΠΎ Ρ Π²Π°ΠΆΠ»ΠΈΠ²ΠΎΡ ΡΠΊΠ»Π°Π΄ΠΎΠ²ΠΎΡ ΡΠ°ΡΠΌΠ°ΠΊΠΎΠ΄ΠΈΠ½Π°ΠΌΡΠΊΠΈ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΡΠ²Π°Π½ΠΎΠ³ΠΎ ΡΠ°ΡΠΌΠ°ΠΊΠΎΠ»ΠΎΠ³ΡΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΡ ΡΠΊ Π·Π°ΡΠΎΠ±Π°, ΡΠΊΠΈΠΉ ΠΏΡΠΎΠΏΠΎΠ½ΡΡΡΡΡΡ ΠΏΡΠΈ Π·Π°ΠΏΠ°Π»ΡΠ½ΠΎ-Π΄Π΅ΡΡΡΡΠΊΡΠΈΠ²Π½ΠΈΡ
ΠΏΡΠΎΡΠ΅ΡΠ°Ρ
.ΠΠΈΡΠ½ΠΎΠ²ΠΊΠΈ. ΠΠ΄Π°ΡΠ½ΡΡΡΡ Π΄ΠΎΡΠ»ΡΠ΄ΠΆΡΠ²Π°Π½ΠΎΠ³ΠΎ ΠΊΡΠ΅ΠΌΡ Π·ΠΌΠ΅Π½ΡΡΠ²Π°ΡΠΈ ΡΡΠ΄ΠΈΠ½Π½Ρ ΠΏΡΠΎΠ½ΠΈΠΊΠ½ΡΡΡΡ ΠΏΡΠΈ Π²Π²Π΅Π΄Π΅Π½Π½Ρ ΡΡΠ·Π½ΠΎΠΌΠ°Π½ΡΡΠ½ΠΈΡ
ΡΠ»ΠΎΠ³ΠΎΠ³Π΅Π½Π½ΠΈΡ
ΡΠ΅ΡΠΎΠ²ΠΈΠ½ ΡΠ²ΡΠ΄ΡΠΈΡΡ ΠΏΡΠΎ Π±Π°Π³Π°ΡΠΎΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΡ ΠΏΡΠΎΡΠΈΠ·Π°ΠΏΠ°Π»ΡΠ½Ρ Π΄ΡΡ, ΠΏΠΎΠ²βΡΠ·Π°Π½Ρ Π· Π°Π½ΡΠΈΠΎΠΊΡΠΈΠ΄Π°Π½ΡΠ½ΠΈΠΌΠΈ Ρ ΠΌΠ΅ΠΌΠ±ΡΠ°Π½ΠΎΡΡΠ°Π±ΡΠ»ΡΠ·ΡΠ²Π°Π»ΡΠ½ΠΈΠΌΠΈ Π²Π»Π°ΡΡΠΈΠ²ΠΎΡΡΡΠΌΠΈ Π΄ΡΡΡΠΈΡ
ΡΠ΅ΡΠΎΠ²ΠΈΠ½ ΠΊΡΠ΅ΠΌΡ
- β¦