Well-posedness and stability results for the Gardner equation

In this article we present local well-posedness results in the classical Sobolev space H^s(R) with s > 1/4 for the Cauchy problem of the Gardner equation, overcoming the problem of the loss of the scaling property of this equation. We also cover the energy space H^1(R) where global well-posedness follows from the conservation laws of the system. Moreover, we construct solitons of the Gardner equation explicitly and prove that, under certain conditions, this family is orbitally stable in the energy space.Comment: 1 figure. Accepted for publication in Nonlin.Diff Eq.and App

Lymphotoxins and cytomegalovirus cooperatively induce interferon-beta, establishing host-virus détente

Tumor necrosis factor (TNF)-related cytokines regulate cell death and survival and provide strong selective pressures for viruses, such as cytomegalovirus (CMV), to evolve counterstrategies in order to persist in immune-competent hosts. Signaling by the lymphotoxin (LT)-β receptor or TNF receptor-1, but not Fas or TRAIL receptors, inhibits the cytopathicity and replication of human CMV by a nonapoptotic, reversible process that requires nuclear factor κB (NF-κB)-dependent induction of interferon-β (IFN-β). Efficient induction of IFN-β requires virus infection and LT signaling, demonstrating the need for both host and viral factors in the curtailment of viral replication without cellular elimination. LTα-deficient mice and LTβR-Fc transgenic mice were profoundly susceptible to murine CMV infection. Together, these results reveal an essential and conserved role for LTs in establishing host defense to CMV

Dynamics of a structured slug population model in the absence of seasonal variation

We develop a novel, nonlinear structured population model for the slug Deroceras reticulatum, a highly significant agricultural pest of great economic impact, in both organic and non-organic settings. In the absence of seasonal variations, we numerically explore the effect of life history traits that are dependent on an individual's size and measures of population biomass. We conduct a systematic exploration of parameter space and highlight the main mechanisms and implications of model design. A major conclusion of this work is that strong size dependent predation significantly adjusts the competitive balance, leading to non-monotonic steady state solutions and slowly decaying transients consisting of distinct generational cycles. Furthermore, we demonstrate how a simple ratio of adult to juvenile biomass can act as a useful diagnostic to distinguish between predated and non-predated environments, and may be useful in agricultural settings

High Gain Amplifier with Enhanced Cascoded Compensation

A two-stage CMOS operational amplifier with both, gain-boosting and indirect current feedback frequency compensation performed by means of regulated cascode amplifiers, is presented. By using quasi-floating-gate transistors (QFGT) the supply requirements, the number of capacitors and the size of the compensation capacitors respect to other Miller schemes are reduced. A prototype was fabricated using a 0.5 μm technology, resulting, for a load of 45 pF and supply voltage of 1.65 V, in open-loop-gain of 129 dB, 23 MHz of gain-bandwidth product, 60o phase margin, 675 μW power consumption and 1% settling time of 28 ns

A simple model on the influence of the greenhouse effect on the efficiency of solar-to-wind energy conversion

In the present paper we study the Gordon and Zarmi model (Am. J. Phys., 57 (1989)995)for dealing with the earth’s wind energy as a solar-driven Carnot-like heat engine, incorporating the role of the greenhouse effect on the performance of this heat engine model, following the De Vos approach. We find that when the greenhouse effect is considered only at the low-temperature half part of the cycle, the efficiency of the conversion of solar energy into wind energy strongly depends on the greenhouse effect under both maximum-power and maximum-ecological-function conditions. We also analyze the De Vos-van der Wel model corresponding to the so-called two-reservoir case and find that the efficiency of conversion of solar energy into wind energy under maximum ecological function reaches a reasonable value within the interval of values reported in the literature

CO2 Kuznets Curve Revisited: From Cross-Sections to Panel Data Models

The Environmental Kuznets Curve (EKC) predicts that environmental degradation intensifies when per capita income increases and subsequently subsides after a certain income level is reached, resulting in an inverted U-shaped relationship. There is abundant literature on the topic that corroborates the existence of a positive income elasticity for environmental quality. However, results are controversial. We take the case of CO2, by comparing the results of the cross-sectional estimates with those derived from a panel approach. To this end, we use data from 182 countries during the period 1992-2011. We found that the EKC hypothesis is acceptable under both approaches, although the estimated turning points in cross-sections seem unreliable. Our application underlines the importance of adequately address central problems such as heterogeneity, structural breaks and spatial interaction. La curva de Kuznets (EKC) predice que la degradación medioambiental se intensifica inicialmente al aumentar la renta per cápita, para disminuir a continuación tras haber alcanzado cierto nivel de renta o turning point. Esta estructura se traduce en una relación en forma de U invertida entre ambas variables. Existe abundante literatura sobre el tema que corrobora la existencia de una elasticidad neta positiva para la calidad medioambiental. Sin embargo, los resultados son controvertidos. Analizamos el caso de CO2 comparando los resultados de las estimaciones transversales, con las derivadas de un enfoque panel. Para ello utilizamos datos de 182 países durante el periodo 1992-2011. Comprobamos que la hipótesis EKC resulta aceptable bajo ambos enfoques, aunque los turning point estimados en los cortes transversales son poco creíbles. Nuestra aplicación subraya la importancia de tratar adecuadamente problemas centrales como la heterogeneidad, las rupturas estructurales y la interacción espacial

Measuring resilience to economic shocks: an application to Spain

In this paper, we evaluate Spanish regions’ resistance to the economic crisis under three main resilience notions: “adaptative, ” “engineering” and “ecological.” “Adaptative” resilience is measured through a traditional shift-share approach applied to employment, whereas “engineering” and “ecological” resilience pay attention to growth path and total employment level, in the pre- and post-crisis period. The paper presents an application of the different notion of resilience to the case of Spanish provinces in the last years. We find that provinces with sectoral structure and location advantages, or those with locational advantages in the post-crisis period (according to the “adaptative” resilience measure), exhibit a significantly lower “drop” in growth (according to the “engineering” and “ecological” resilience measure). Furthermore, we conclude that the probability of presenting a better behavior (lower “drop” in growth than the average) increases for those regions specialized in the service sector before the crisis. As expected, the worse behavior has correspond to those regions specialized in the pre-crisis period in the construction sector

Influence of Quaternary Benzophenantridine and Protopine Alkaloids on Growth Performance, Dietary Energy, Carcass Traits, Visceral Mass, and Rumen Health in Finishing Ewes under Conditions of Severe Temperature-humidity Index.

Twenty Pelibuey×Katahdin ewes (35±2.3 kg) were used to determine the effects of the consumption of standardized plant extract containing a mixture of quaternary benzophenanthridine alkaloids and protopine alkaloids (QBA+PA) on growth performance, dietary energetics, visceral mass, and ruminal epithelial health in heat-stressed ewes fed with a high-energy corn-based diet. The basal diet (13.9% crude protein and 2.09 Mcal of net energy [NE] of maintenance/kg of dry matter) contained 49.7% starch and 15.3% neutral detergent fiber. Source of QBA+PA was Sangrovit RS (SANG) which contains 3 g of quaternary benzophenathridine and protopine alkaloids per kg of product. Treatments consisted of a daily consumption of 0 or 0.5 g SANG/ewe. Ewes were grouped by weight and assigned to 10 pens (5 pens/treatment), with two ewes per pen. The experimental period lasted 70 days. The mean temperature humidity index during the course of this experiment was 81.7±1.0 (severe heat stress). There were no treatment effects on water intake. Dry matter intake was not affected (p = 0.70) by treatments, but the group fed SANG had a numerically (11.2%) higher gain in comparison to the control group, SANG improved gain efficiency (8.3%, p = 0.04), dietary NE (5.2%, p<0.01) and the observed-to-expected NE (5.9%, p<0.01). Supplemental SANG did not affect (p≥0.12) carcass characteristics, chemical composition of shoulder, and organ weights (g/kg empty body weight) of stomach complex, intestines, and heart/lung. Supplemental SANG decreased liver weight (10.3%, p = 0.02) and increased visceral fat (16.9%, p = 0.02). Rumen epithelium of ewes fed SANG had lower scores for cellular dropsical degeneration (2.08 vs 2.34, p = 0.02), parakeratosis (1.30 vs 1.82, p = 0.03) and neutrophil infiltration (2.08 vs 2.86, p = 0.05) than controls. It is concluded that SANG supplementation helped ameliorate the negative effects of severe heat on growth performance of feedlot ewes fed high-energy corn-based diets. Improvement in energetic efficiency may have been mediated, in part, by anti-inflammatory effects of supplemental SANG and corresponding enhancement of nutrient uptake

Ultra Low-Power Analog Median Filters

The design and implementation of three analog median filter topologies, whose transistors operate in the deep weak-inversion region, is described. The first topology is a differential pairs array, in which drain currents are driven into two nodes in a differential fashion, while the second topology is based on a wide range OTA, which is used to maximize the dynamic range. Finally, the third topology uses three range-extended OTAs. The proposed weak-inversion filters were designed and fabricated in ON Semiconductor 0.5 micrometer technology through MOSIS. Experimental results of three-input fabricated prototypes for all three topologies are show, where power consumptions of 90nW in the first case, and 270nW in the other two cases can be noticed. A dual power supply +/-1.5 Volts were used