Octupole correlations near 110Te

The lifetime of the 2+ and 9-, 11-, 13-, 15- states in the neutron-deficient 110Te was measured for the first time using the recoil distance Doppler shift technique. The reported value of the reduced transition probability B(E2;0+g.s?2+)=4.3(8)×103e2fm4 supports the systematic for even-mass Te isotopes and was interpreted in the framework of the large-scale shell model and cranked shell model calculations. The measured reduced transition probabilities in the negative-parity yrast band revealed the upward trend towards the high spins. The enhanced collectivity is discussed in terms of the tilted axis cranking approach and the symmetry configuration mixing method with the Gogny D1S interaction.The authors would like to thank the technical staff of the LNL Legnaro facility for their assistance in providing excellent operation of the XTU-tandem accelerator. The authors wish to acknowledge the support of local engineers P. Cocconi and R. Isocrate. The work was partially supported by the DoE Grant No. DE-FG02-95ER4093 and Spanish MICINN Grant No. PGC2018-094583-B-I00

System Virtualization Tools for Software Development

The configuration complexity of preproduction sites coupled with access-control mechanisms often impede the software development life cycle. Virtualization is a cost-effective way to remove such barriers and provide a test environment similar to the production site, reducing the burden in IT administrators. An Eclipse-based virtualization tool framework can offer developers a personal runtime environment for launching and testing their applications. The authors have followed a model-driven architecture (MDA) approach that integrates best-of-breed virtualization technologies, such as Xen and VDE.ITECBAN is an IT innovation project partially funded by CENIT (a Spanish public R&D program). We're grateful to MITYC (Ministerio de Industria, Turismo y Comercio) and CDTI (Centro para el Desarrollo Tecnológico e Industrial) for supporting ITECBAN through CENIT

Observation and Spectroscopy of New Proton-Unbound Isotopes 30Ar and 29Cl: An Interplay of Prompt Two-Proton and Sequential Decay

Previously unknown isotopes Ar30 and Cl29 have been identified by measurement of the trajectories of their in-flight decay products S28+p+p and S28+p, respectively. The analysis of angular correlations of the fragments provided information on decay energies and the structure of the parent states. The ground states of Ar30 and Cl29 were found at 2.25+0.15−0.10 and 1.8±0.1  MeV above the two- and one-proton thresholds, respectively. The lowest states in Ar30 and Cl29 point to a violation of isobaric symmetry in the structure of these unbound nuclei. The two-proton decay has been identified in a transition region between simultaneous two-proton and sequential proton emissions from the Ar30 ground state, which is characterized by an interplay of three-body and two-body decay mechanisms. The first hint of a fine structure of the two-proton decay of Ar∗30(2+) has been obtained by detecting two decay branches into the ground and first-excited states of the S28 fragment.A. G., S. K., S. R., and P. S. were supported by the Helmholtz Association Grant No. IK-RU-002. L. V. G. was partly supported by the Ministry of Education and Science of the Russian Federation Grant No. NSh- 932.2014.2. A. F., A. G., L. V. G., S. K., P. S., and R. S. were partly supported by the Russian Foundation for Basic Research Grant No. 14-02-00090-a. This work was partly supported by the Polish National Science Center under Contract No. UMO-2011/01/B/ST2/01943. A. A. C. acknowledges support by the Polish Ministry of Science and Higher Education by Grant No. 0079/DIA/ 2014/43 (Grant Diamentowy). M. P. and X. X. are grateful for a support from the Helmholtz International Center for FAIR (HIC for FAIR). Y. L. was supported by the Helmholtz-CAS Joint Research Group Grant No. HCJRG- 108. J. M. E. acknowledges support from the FPA2009- 08848 contract (MICINN, Spain

Routine management of locally advanced cervical cancer with concurrent radiation and cisplatin. Five-year results

BACKGROUND: Globally, cervical cancer primarily affects socially disadvantaged women. Five randomized trials were the foundation for adopting cisplatin-based chemotherapy during radiation as the standard of care for high-risk patients after primary radical hysterectomy who require adjuvant radiation and for locally advanced patients treated with definitive radiation. These results were obtained in clinical trials performed in carefully prepared academic centers; hence, we sought to determine whether these results could be reproduced when patients were treated on an out-of-protocol basis. METHODS: We reviewed the files of 294 patients with locally advanced cervical cancer who received radiation plus weekly cisplatin as routine management between 1999 to 2003, and analyzed treatment compliance, response rate, toxicity, and survival. RESULTS: A total of 294 patients who received radiation and cisplatin were analyzed. Mean age was 43.8 years (range, 26–68 years). The majority of cases were squamous cell carcinoma (87.8%), and distribution according to International Federation of Gynecology and Obstetrics (FIGO) stage was as follows: IB2-IIA, 23%; IIB, 53.3%, and IIIB, 23%; there were only two IVA cases. Overall, 96% of patients completed external beam, and intracavitary therapy. The majority of patients (67%) received the planned six courses of weekly cisplatin. Complete responses were achieved in 243 (83%) patients, whereas 51 (17%) had either persistent (32 patients, 10.8%) or progressive (19 patients, 6.4%) disease. At median follow-up (28 months; range, 2–68 months), 36 patients (12.2%) have relapsed (locally 30.5, and systemically, 69.5%). The most common toxicities were hematologic and gastrointestinal, in the majority of cases considered mild-moderate. At median follow-up (28 months; range, 2–68 months), overall and progression-free survival are 76.5 and 67%, respectively. CONCLUSION: Our results support use of chemoradiation with six weekly applications of cisplatin at 40 mg/m(2 )during external radiation for routine management of locally advanced cervical cancer

Effect of the use of videos in the pre-class preparation of laboratory sessions taught by flip teaching

[EN] Nowadays, it is well stablished the effectiveness of flip teaching in different areas. Video is widely used as a pre-class learning material and it is progressively replacing text-document materials. The students, 70 in total, are enrolled in the laboratory practice of the subject of Physics (Bachelor¿s Degree: Industrial Electronics and Automation Engineering) at the Universitat Politècnica de València. Student¿s perception data were collected from the results of a survey. Students were asked about the usefulness of the videos and the in-class work, paying special attention to the roll of the instructor in relation to the flip teaching methodology and the pre-class material. The students were divided into two groups. In one of them, the videos were recorded by the same instructor present at the lab session, whereas the other group, the videos used were recorded by instructors different from the instructor present at the lab. The results indicate that students feel that the videos are very useful, rather than the written documents. They attribute a high value to the instructor in the lab session as they feel more confident with their work and they can ask for help when needed. They value positively the possibility of work autonomously. Small differences have been found in the opinion of both groups being the higher in the question that concerns the preference of the videos respect to the text.This work has been supported by the Universitat Politècnica de València through the Project of Innovation and Educational Improvement Program (Projects PIME/2018/B26 and PIME/2018/B25 Convocatoria de Proyectos de Innovación y Convergencia).Meseguer Dueñas, JM.; Quiles Casado, SDLS.; Sabater I Serra, R.; Serrano, M.; Gómez-Tejedor, J.; García-Sánchez, TM.; Tort-Ausina, I.... (2020). Effect of the use of videos in the pre-class preparation of laboratory sessions taught by flip teaching. Iated. 6107-6112. https://doi.org/10.21125/inted.2020.1654S6107611

Review of concepts in therapeutic decision-making in HER2-negative luminal metastatic breast cancer

Purpose: Hormone receptor (HR)-positive, Human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC) requires a therapeutic approach that takes into account multiple factors, with treatment being based on anti-estrogen hormone therapy (HT). As consensus documents are valuable tools that assist in the decision-making process for establishing clinical strategies and optimize the delivery of health services, this consensus document has been created with the aim of developing recommendations on cretiera for hormone sensitivity and resistance in HER2-negative luminal MBC and facilitating clinical decision-making. Methods: This consensus document was generated using a modification of the RAND/UCLA methodology, which included the definition of the project and identification of issues of interest, a non-exhaustive systematic review of the literature, an analysis and synthesis of the scientific evidence, preparation of recommendations, and external evaluation with a panel of 64 medical oncologists specializing in breast cancer. Results: A Spanish panel of experts reached consensus on 32 of the 32 recommendations/conclusions presented in the first round and were accepted with an approval rate of 100% about definition of metastatic disease not susceptible to local curative treatment, definition of hormone sensitivity and hormone resistance in metastatic luminal disease and therapeutic decision-making. Conclusion: We have developed a consensus document with recommendations on the treatment of patients with HER2-negative luminal MBC that will help to improve therapeutic benefits

Hacia una aplicación efectiva de Metodología Inversa en las asignaturas de Física de primeros cursos de Grado

[ES] En el presente trabajo se presenta la experiencia de la implantación de la docencia inversa en asig-naturas de la materia de física en primeros cursos de las titulaciones de Ingeniería Aeroespacial, Ingeniería Informática e Ingeniería Biomédica. Para obtener la opinión del alumnado se han lle-vado a cabo una serie de encuestas con respuestas abiertas y de opción multiple. Los resultados obtenidos muestran una gran variabilidad de opiniones, incluso dentro del alumnado perteneciente a un mismo grupo. En general los alumnos valoran positivamente el esfuerzo realizado por el pro-fesorado, pero es necesario que los profesores lleven a cabo una serie de medidas para que la implantación de la metodología sea exitosa. Entre ellas, resulta necesario que los contenidos dis-ponibles estén perfectamente estructurados y accesibles, que los contenidos sean interactivos y per-mitan dar información sobre cómo se desarrolla el proceso de aprendizaje, que el nivel de carga de trabajo del alumnado sea sostenible y que el profesorado sea consciente de que la transición en el modelo de aprendizaje requiere de cierta empatía. La implantación de la docencia inversa es por tanto un proceso complejo que requiere una adaptación específica al contexto docente donde se aplica.[EN] En el presente trabajo se presenta la experiencia de la implantación de la docencia inversa en asig-naturas de la materia de física en primeros cursos de las titulaciones de Ingeniería Aeroespacial, Ingeniería Informática e Ingeniería Biomédica. Para obtener la opinión del alumnado se han lle-vado a cabo una serie de encuestas con respuestas abiertas y de opción multiple. Los resultados obtenidos muestran una gran variabilidad de opiniones, incluso dentro del alumnado perteneciente a un mismo grupo. En general los alumnos valoran positivamente el esfuerzo realizado por el pro-fesorado, pero es necesario que los profesores lleven a cabo una serie de medidas para que la implantación de la metodología sea exitosa. Entre ellas, resulta necesario que los contenidos dis-ponibles estén perfectamente estructurados y accesibles, que los contenidos sean interactivos y per-mitan dar información sobre cómo se desarrolla el proceso de aprendizaje, que el nivel de carga de trabajo del alumnado sea sostenible y que el profesorado sea consciente de que la transición en el modelo de aprendizaje requiere de cierta empatía. La implantación de la docencia inversa es por tanto un proceso complejo que requiere una adaptación específica al contexto docente donde se aplica.Gómez Tejedor, JA.; Tort-Ausina, I.; Vidaurre, A.; Meseguer Dueñas, JM.; Molina-Mateo, J.; Riera, J. (2021). Hacia una aplicación efectiva de Metodología Inversa en las asignaturas de Física de primeros cursos de Grado. En IN-RED 2020: VI Congreso de Innovación Educativa y Docencia en Red. Editorial Universitat Politècnica de València. 83-94. https://doi.org/10.4995/INRED2020.2020.11934OCS839

Fusion of 8He with 206Pb around Coulomb barrier energies

The experimental study of the fusion of light neutron-rich nucleus 8He with 206Pb is reported in this work. A fusion stack of 206Pb targets has been used for this study. The most prominent evaporation residue (210Po), which has half-life of 138 days and decays by alpha emission, is populated in the reaction. Radiochemical analysis technique is used to extract the yield of this evaporation residue.Ministerio de Ciencia e Innovavión FPA2007-63074European Union 21269

Cohesion in crumb rubber modified bitumen

El objetivo de este artículo es estudiar la influencia del polvo de neumático en la mejora de la cohesión proporcionada por la adición del polvo de neumático al betún mediante el método UCL. El método UCL es un procedimiento desarrollado para caracterizar ligantes bituminosos, basado en la evaluación de la cohesión dada por una cantidad determinada de un betún o un mástico bituminoso a unos áridos de granulometría establecida (mezcla patrón). Se ha empleado este método porque permite valorar al mismo tiempo los dos procedimientos de incorporación del polvo de neumático al betún: vía seca y vía húmeda. El procedimiento seco se lleva a cabo añadiendo el polvo de neumático a la mezcla como si fuera un filler, de modo que el polvo de neumático y el ligante se mezclan durante la fabricación, extendido y compactación de la mezcla. En el procedimiento húmedo, hay una mezcla previa del ligante con el polvo de neumático, por lo que aquél se añade a la mezcla cuando ya ha sido modificado. También se ha estudiado la influencia de los tiempos de digestión. Se comparan los dos procedimientos, seco con y sin digestión, y húmedo. El segundo presenta una clara ventaja, especialmente cuando los ligantes son fabricados con dispersión microscópica

Interaction of 8He with 208Pb at near-barrier energies: 4He and 6He production

Angular distributions for the inclusive 4He and 6He production cross sections in the 8He+208Pb system at incident energies of 16 and 22 MeV measured at the SPIRAL facility of the GANIL laboratory are presented. Using a combination of kinematical arguments and distorted wave Born approximation (DWBA) calculations, neutron transfer reactions were inferred to be the dominant contributors to both inclusive cross sections. Model-dependent values for the ratios of two- to one-neutron stripping, s2n/s1n, were derived and compared with previous results for 8He and 6He projectiles incident on other heavy targets. Three- and four-neutron stripping were inferred to be the main processes leading to 4He production, although the exact mechanism remains to be elucidated.The authors would like to thank the staff of the GANIL accelerator facility for providing the high-quality 8He beam. This work was supported in part by Grants No. FPA-2010-22131-CO2-01 (FINURA) and No. FPA2013-47327-C2-1-R from the Spanish Ministry of Economy and Competitiveness, UNAM-PAPIIT IA103218 (Mexico); Grant No. N202 033637 from the Ministry of Science and Higher Education of Poland; the National Science Centre of Poland under Contracts No. 2013/08/M/ST2/00257 (LEA-COPIGAL) and No. 2014/14/M/ST2/00738 (COPIN-INFN Collaboration); and Grant No. EUI2009-04163432 (EUROGENESIS) from the European Science Foundation