Tinjauan Bangkitan Dan Tarikan Perjalanan Kelurahan Kecamatan Rambah, Pasir Pengaraian

Kecamatan Rambah merupakan daerah yang per kembangan pembangunannya cukup pesat. Hal ini ditandai dengan adanya pembangunan disegala bidang, seperti pembangunan pasar modern, pembangunan gedung daerah, pembangunanMesjid agung islamic center dan peningkatan sarana lainnya. Kecamatan Rambah juga merupakan kawasan daerah perkantoran, pertokoan, sekolahan, tempat ibadah. Dengan adanya pembangunan dan peningkatan sarana maupun prasarana tersebut, hal ini menjadikan Kecamatan Rambah s ebagai public center bagi masyarakat Kabupaten RokanHulu. Kondisi ini tentunya akan menimbulkan pengaruh terhadap bangkitan dan tarikan perjalanan di Kecamatan Rambah, sehingga perlu adanya analisa terhadap bangkitan dan tarikan perjalanan di kecamatan tertsebut

Improving the lipid profile in hypercholesterolemia-induced rabbit by supplementation of germinated brown rice.

It is imperative that there be a diet designed specifically to improve lipid profile in order to impede the progress of atherosclerosis. Because rice is a staple food in Asia, it will be chosen as the diet of interest. This study sets out to discover whether consumption of different processed rice diets may result in a change of the lipid profile. The experiment was done on male New Zealand white rabbits after 10 weeks of treatment with diet containing 0.5% cholesterol. The experimental diets include white rice (WR), brown rice (BR), and germinated brown rice (GBR). Among them, rabbits fed a GBR diet demonstrated significantly lower levels of total cholesterol (TC), low-density lipoprotein (LDL), LDL/HDL, and atherogenic index (AI) and a higher level of high-density lipoprotein (HDL). Results from atherosclerotic plaque assessment further support the findings. The level of malondialdehyde (MDA), which acts as an indicator for oxidative stress, was also reduced by GBR diet. The positive change in lipid profile in the rabbits fed GBR appeared to correspond with the higher amounts of γ-oryzanol, tocopherol, and monounsaturated fatty acid (MUFA) content

Dose-response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study in Bangladesh

<p>Abstract</p> <p>Background</p> <p>Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh.</p> <p>Methods</p> <p>A total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects' hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) and alanine transaminase (ALT) were then assayed.</p> <p>Results</p> <p>Arsenic concentrations in the subjects' hair and nails were positively correlated with arsenic levels in the drinking water. As regards the exposure-response relationship with arsenic in the drinking water, the respective activities of ALP, AST and ALT were found to be significantly increased in the high-exposure groups compared to the lowest-exposure groups before and after adjustments were made for different covariates. With internal exposure markers (arsenic in hair and nails), the ALP, AST and ALT activity profiles assumed a similar shape of dose-response relationship, with very few differences seen in the higher groups compared to the lowest group, most likely due to the temporalities of exposure metrics.</p> <p>Conclusions</p> <p>The present study demonstrated that arsenic concentrations in the drinking water were strongly correlated with arsenic concentrations in the subjects' hair and nails. Further, this study revealed a novel exposure- and dose- response relationship between arsenic exposure metrics and serum hepatic enzyme activity. Elevated serum hepatic enzyme activities in the higher exposure gradients provided new insights into arsenic-induced liver toxicity that might be helpful for the early prognosis of arsenic-induced liver diseases.</p

Personality profiles of cultures: aggregate personality traits

Personality profiles of cultures can be operationalized as the mean trait levels of culture members. College students from 51 cultures rated an individual from their country whom they knew well (N = 12, 156). Aggregate scores on Revised NEO Personality Inventory scales generalized across age and gender groups, approximated the individual-level Five-Factor Model, and correlated with aggregate self-report personality scores and other culture-level variables. Results were not attributable to national differences in economic development or to acquiescence. Geographical differences in scale variances and mean levels were replicated, with Europeans and Americans generally scoring higher in Extraversion than Asians and Africans. Findings support the rough scalar equivalence of NEO-PI-R factors and facets across cultures, and suggest that aggregate personality profiles provide insight into cultural differences

A virtual screening approach for identifying plants with anti H5N1 neuraminidase activity

Recent outbreaks of highly pathogenic and occasional drug-resistant influenza strains have highlighted the need to develop novel anti-influenza therapeutics. Here, we report computational and experimental efforts to identify influenza neuraminidase inhibitors from among the 3000 natural compounds in the Malaysian-Plants Natural-Product (NADI) database. These 3000 compounds were first docked into the neuraminidase active site. The five plants with the largest number of top predicted ligands were selected for experimental evaluation. Twelve specific compounds isolated from these five plants were shown to inhibit neuraminidase, including two compounds with IC50 values less than 92 μM. Furthermore, four of the 12 isolated compounds had also been identified in the top 100 compounds from the virtual screen. Together, these results suggest an effective new approach for identifying bioactive plant species that will further the identification of new pharmacologically active compounds from diverse natural-product resources

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

The isomorphic model, designing as knowledge creation

Designing is a fundamental activity that supports the introduction, development and implementation of products, services, practices and systems. In the Architectural domain, design facilitates the process of developing a solution to reallife problems through a collaborative process of refinement, analysis, synthesis, assessment and evaluation between expert and novice designers or students and tutors. The potentials of this collaborative process lie above architectural practice and education but it is also a process of knowledge interaction, development and integration. However, the concept of design as knowledge creation is under-researched. Greater understanding of the methods, strategies and tactics employed by designers in facilitating design activities will be the focus of this study in uncovering certain unique characteristics of knowledge creation adopted from Nonaka (1994) in design. Design and knowledge creation processes are collaborative facets that facilitate the creation, sharing and conversion of knowledge, artefacts and product. Some literature has mentioned a link between design and knowledge creation but, to date, there is no provision of substantial properties that prove the isomorphism between them. This research conducted a retrospective analysis of fifteen weeks of design activities between seven design students and their design tutor working together to solve a given design task. The research used observation and subject interviews to validate the observed data. Findings in the studies have explained there exists a link between the two domains. The Socialization, Externalization, Combination and Internalization (SECI) model of knowledge creation and the Analysis-Synthesis Bridge Model are used as a benchmark for the study. Four collaborative features of the design process describe the link between the two domains. Experience and Imagining (E.I), Imagining and Sketching (I.S), Sketching and Modelling (S.M) and Models and Experience (M.E) comprise the four identified features. Using these features, the study has been able to adopt the SECI model to uncover the Isomorphic position of design and knowledge creation

Pelatihan Instalasi Windows Komputer/laptop pada Masyarakat Desa Panggung, Kecamatan Pelaihari

Community service entitled “COMPUTER/LAPTOP WINDOWS INSTALLATION TRAINING IN DESA PANGGUNG COMMUNITIES, KECAMATAN PELAIHARI” has the aim of providing knowledge and skills for The Apparatuses of Desa Panggung in performing simple windows installations on their computers/laptops independently. The method used in carrying out this community service is to provide material directly and practice how to install Windows 10 on a laptop using virtual box tools. In addition, there was also a discussion method regarding the installation of windows with the participants. &nbsp; Community service in analyzing the level of understanding of the apparatus in the material that has been submitted by being given simple questions related to the material. The result of the activity based on the question and answer conducted between the participants and the presenters was an increase in knowledge about Windows Installation. The expected result of community service activities is that the participants can have knowledge in repairing their computers/laptops which includes the installation of the Windows operating system, installation of supporting software, and overcoming trouble if simple problems arise at any time