Axion-like-particle decay in strong electromagnetic backgrounds

The decay of a massive pseudoscalar, scalar and U(1) boson into an electron-positron pair in the presence of strong electromagnetic backgrounds is calculated. Of particular interest is the constant-crossed-field limit, relevant for experiments that aim to measure high-energy axion-like-particle conversion into electron-positron pairs in a magnetic field. The total probability depends on the quantum nonlinearity parameter - a product of field and lightfront momentum invariants. Depending on the seed particle mass, different decay regimes are identified. In the below-threshold case, we find the probability depends on a non-perturbative tunnelling exponent depending on the quantum parameter and the particle mass. In the above-threshold case, we find that when the quantum parameter is varied linearly, the probability oscillates nonlinearly around the spontaneous decay probability. A strong-field limit is identified in which the threshold is found to disappear. In modelling the fall-off of a quasi-constant-crossed magnetic field, we calculate probabilities beyond the constant limit and investigate when the decay probability can be regarded as locally constant.Comment: 22 pages, 7 figure

The effect of low volume sprint interval training in patients with non-alcoholic fatty liver disease

Objectives: Exercise is an important part of disease management in patients with non-alcoholic fatty liver disease (NAFLD), but adherence to current exercise recommendations is poor. Novel low-volume sprint interval training (SIT) protocols with total training time commitments of ≤30 min per week have been shown to improve cardiometabolic risk and functional capacity in healthy sedentary participants, but the efficacy of such protocols in the management of NAFLD remains unknown. The aim of the present study was to examine whether a low-volume SIT protocol can be used to improve liver function, insulin resistance, body composition, physical fitness, cognitive function and general well-being in patients with NAFLD.Methods: In the present study, 7 men and 2 women with NAFLD (age: 45±8 y, BMI: 28.7±4.1 kg·m−2) completed a 6-week control period followed by 6 weeks of twice-weekly SIT sessions (5-10×6-s ‘all-out’ cycle sprints). Body composition, blood pressure, liver function, metabolic function, functional capacity, cognitive function and quality of life were assessed at baseline, following the control period, and following the SIT intervention.Results: Walking speed during the walk test (+12%), estimated V̇O2max (+8%), verbal fluency (+44%), and blood platelet count (+12%; all p<0.05) significantly increased during the control period. These measures remained significantly raised compared to baseline following the SIT intervention, but did not significantly change any further compared to the post-control time-point. Diastolic blood pressure decreased from 87±10 to 77±8 mm Hg from the end of the control period to the end of the SIT intervention (p<0.05).Conclusion: This study does not support the use of 6 weeks of a low volume SIT protocol involving twice-weekly sessions with 5-10×6-s ‘all-out’ cycle sprints as an intervention for NAFLD disease management

Shape-dependent Depinning of a Domain Wall by a Magnetic Field and a Spin-Polarized Current

The effect of sample shape on the depinning of the domain wall (DW) driven by an applied magnetic field or a spin-polarized current is studied theoretically. The shape effect resulting from the modulation of the sample width (geometric pinning) can essentially affect the DW depinning. We found a good agreement between the ratios of the critical values of the magnetic field and the spin-polarized current predicted by the theory and measured in the experiment.Comment: 9 pages, 5 figure

The impact of broadband in schools

The report reviews evidence for the impact of broadband in English schools, exploring; Variations in provision in level of broadband connectivity; Links between the level of broadband activity and nationally accessible performance data; Aspects of broadband connectivity and the school environment that contribute to better outcomes for pupils and teachers; Academic and motivational benefits associated with educational uses of this technology

Aerodynamic characteristics of a hypersonic research airplane concept having a 70 deg swept double-delta wing at Mach numbers from 0.80 to 1.20, with summary of data from 0.20 to 6.0

The static longitudinal, lateral, and directional stability characteristics of a hypersonic research airplane concept having a 70 deg swept double-delta wing were investigated. Force tests were conducted in the Langley 8 foot transonic pressure tunnel for a Reynolds number (based on fuselage length) range of 6.30 x 10 to the 6th power to 7.03 x 10 to the 6th power, at angles of attack from about -4 deg to 23 deg, and at angles of sideslip of 0 deg and 5 deg. The configuration variables included the wing planform, tip fins, the center vertical tail, and scramjet engine modules. Variations of the more important aerodynamic parameters with Mach number for Mach numbers from 0.20 to 6.0 are summarized. A state-of-the-art example of theoretically predicting performance parameters and static longitudinal and directional stability over the Mach number range is included

Learning the latent structure of collider events

We describe a technique to learn the underlying structure of collider events directly from the data, without having a particular theoretical model in mind. It allows to infer aspects of the theoretical model that may have given rise to this structure, and can be used to cluster or classify the events for analysis purposes. The unsupervised machine-learning technique is based on the probabilistic (Bayesian) generative model of Latent Dirichlet Allocation. We pair the model with an approximate inference algorithm called Variational Inference, which we then use to extract the latent probability distributions describing the learned underlying structure of collider events. We provide a detailed systematic study of the technique using two example scenarios to learn the latent structure of di-jet event samples made up of QCD background events and either tt¯.Fil: Dillon, B. M.. Institute Jo?ef Stefan; EsloveniaFil: Faroughy, D. A.. Universitat Zurich; SuizaFil: Kamenik, J. F.. Institute Jo?ef Stefan; Eslovenia. University of Ljubljana; EsloveniaFil: Szewc, Manuel. Universidad Nacional de San Martín; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

The evolution of reproductive isolation in a simultaneous hermaphrodite, the freshwater snail Physa

<p>Abstract</p> <p>Background</p> <p>The cosmopolitan freshwater snail <it>Physa acuta </it>has recently found widespread use as a model organism for the study of mating systems and reproductive allocation. Mitochondrial DNA phylogenies suggest that <it>Physa carolinae</it>, recently described from the American southeast, is a sister species of <it>P. acuta</it>. The divergence of the <it>acuta/carolinae </it>ancestor from the more widespread <it>P. pomilia </it>appears to be somewhat older, and the split between a hypothetical <it>acuta/carolinae/pomilia </it>ancestor and <it>P. gyrina </it>appears older still.</p> <p>Results</p> <p>Here we report the results of no-choice mating experiments yielding no evidence of hybridization between <it>gyrina </it>and any of four other populations (<it>pomilia, carolinae</it>, Philadelphia <it>acuta</it>, or Charleston <it>acuta</it>), nor between <it>pomilia </it>and <it>carolinae</it>. Crosses between <it>pomilia </it>and both <it>acuta </it>populations yielded sterile F1 progeny with reduced viability, while crosses between <it>carolinae </it>and both <it>acuta </it>populations yielded sterile F1 hybrids of normal viability. A set of mate-choice tests also revealed significant sexual isolation between <it>gyrina </it>and all four of our other <it>Physa </it>populations, between <it>pomilia </it>and <it>carolinae</it>, and between <it>pomilia </it>and Charleston <it>acuta</it>, but not between <it>pomilia </it>and the <it>acuta </it>population from Philadelphia, nor between <it>carolinae </it>and either <it>acuta </it>population. These observations are consistent with the origin of hybrid sterility prior to hybrid inviability, and a hypothesis that speciation between <it>pomilia </it>and <it>acuta </it>may have been reinforced by selection for prezygotic reproductive isolation in sympatry.</p> <p>Conclusions</p> <p>We propose a two-factor model for the evolution of postzygotic reproductive incompatibility in this set of five <it>Physa </it>populations consistent with the Dobzhansky-Muller model of speciation, and a second two-factor model for the evolution of sexual incompatibility. Under these models, species trees may be said to correspond with gene trees in American populations of the freshwater snail, <it>Physa</it>.</p

Fv antibodies to aflatoxin B1 derived from a pre-immunized antibody phage display library system

The production and characterization of recombinant antibodies to aflatoxin B[SUB1] (AFB[SUB1]), a potent mycotoxin and carcinogen is described. The antibody fragments produced were then applied for use in a surface plasmon resonance-based biosensor (BIAcore), which measures biomolecular interactions in 'real-time'. Single chain Fv (scFv) antibodies were generated to aflatoxin B1 from an established phage display system, which incorporated a range of different plasmids for efficient scFv expression. The scFv's were used in the development of a competitive ELISA, and also for the development of surface plasmon resonance (SPR)-based inhibition immunoassays. They were found to be suitable for the detection of AFB[SUB1], in this format, with the assays being sensitive and reproducible