681 research outputs found

    Karbon emisyon politikalarının tersine tedarik zincir ağı tasarımı üzerindeki etkileri

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    Reverse Supply Chain is described as an initiative that plays an important role in the global supply chain for those who seek environmentally responsible solutions for their end-of-life products. The relative economic and environmental benefits of reverse supply chain are influenced by costs and emissions during collection, transportation, recovery facilities, disassembly, recycling, remanufacturing, and disposal of unrecoverable components. The design of reverse supply chain network takes into account social, economic and environmental objectives. This paper addresses the design of reverse supply chain under the three common regulatory policies, strict carbon caps, carbon tax, and carbon cap-and-trade.Küresel tedarik zincirinde önemli bir rol oynayan tersine tedarik zinciri, ömrünü tamamlamış ürünler için çevreye karşı sorumlu çözümler arayanların bir girişimi olarak tanımlanmaktadır. Tersine tedarik zincirinin nispi ekonomik ve çevresel faydaları, toplama, nakliye, geri kazanım tesisleri, demontaj, geri dönüşüm, yeniden imalat ve geri dönüşü olmayan bileşenlerin imha edilmesi sırasında oluşan maliyetler ve emisyonlardan etkilenmektedir. Tersine tedarik zinciri ağ tasarımı sosyal, ekonomik ve çevresel hedefleri dikkate almaktadır. Bu makale, sıkı karbon kapsülleri, karbon vergisi, karbon emisyon üst sınırı ve ticareti olmak üzere üç ortak düzenleyici politikada ters tedarik zincirinin tasarımını ele almaktadır

    The Impact of Carbon Emissions Policies on Reverse Supply Chain Network Design

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    Reverse Supply Chain is described as an initiative that plays an important role in the global supply chain for those who seek environmentally responsible solutions for their end-of-life products. The relative economic and environmental benefits of reverse supply chain are influenced by costs and emissions during collection, transportation, recovery facilities, disassembly, recycling, remanufacturing, and disposal of unrecoverable components. The design of reverse supply chain network takes into account social, economic and environmental objectives. This paper addresses the design of reverse supply chain under the three common regulatory policies, strict carbon caps, carbon tax, and carbon cap-and-trade

    The Impact of Carbon Emissions Policies on Reverse Supply Chain Network Design

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    Reverse Supply Chain is described as an initiative that plays an important role in the global supply chain for those who seek environmentally responsible solutions for their end-of-life products. The relative economic and environmental benefits of reverse supply chain are influenced by costs and emissions during collection, transportation, recovery facilities, disassembly, recycling, remanufacturing, and disposal of unrecoverable components. The design of reverse supply chain network takes into account social, economic and environmental objectives. This paper addresses the design of reverse supply chain under the three common regulatory policies, strict carbon caps, carbon tax, and carbon cap-and-trade

    Sufficiency and Efficiency of Field Training for Radiology Students During Internship Experience in Najran University, Saudi Arabia

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    Purpose: The study was design to evaluate the effectiveness and adequacy of the internship period employing quantitative study descriptive survey approach.   Theoretical framework: Internship is requirement of every student of radiology program of Radiological Sciences patch for the award of bachelor's degree at Najran University, Saudi Arabia. The competency level would demonstrate influence the sufficiency and efficiency of clinical training during internship period which represent six months after completing nine levels of radiology program.   Design\Methodology\Approach: The survey was distributed to the tow levels of the last year of radiological sciences which composed of 81 male and female students which gathered seventy-seven (77) participants. Data collected through a questionnaire and summarized as percentages, frequencies, means and standard deviations using SPSS version 20.0.   Findings: The study revealed un adequacy of the internship period and showed low efficiency due to its short duration.   Research, Practical, Social Implication:The research construct and variables are identified the effectiveness and adequacy of the internship period.this  study will be the modele of internship with a new qualitative change related to a period of time acceptable to students, similar to other universities.   Originality/Value: The originality and value in this study are the framework conceptance and questionnaire that prepared and proved for evaluating the effectiveness and adequacy of the internship period for student of radiology program.   Conclusion: In general internship period must be efficient and adequate to enhance sufficiency and efficiency experience by intern trainees

    Caffeinated Gum Does Not Influence RPE-Regulated Cadence in Recreationally-Active, College Females Regardless of Habitual Caffeine Consumption

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    International Journal of Exercise Science 14(2): 1375-1387, 2021. Caffeine (CAF) has been extensively studied for its ergogenic and analgesic effects during exercise. However, the majority of these studies have been conducted in male populations. This study investigated the effects of acute CAF chewing gum on self-selected exercise intensity during a rating of perceived exertion (RPE) production trial in active females (n = 16, 21.0 ± 2.8 y). Data were also analyzed based on habitual CAF consumption level. Participants completed a V̇O2peak trial, followed by a familiarization and two randomized, triple-blinded experimental RPE production trials on an arm ergometer [clamped resistance, blinded to self-selected cadence (CAD)] with either CAF gum (300 mg; 4.8 ± 0.7 mg/kg-1 body mass) or placebo (PLA), at a prescribed RPE of 4 and 7 (10 min each). Self-selected CAD did not statistically differ (p \u3e 0.05) between CAF or PLA for an RPE4 (37.7 ± 1.6 vs. 37.6 ± 1.6 rev·min-1) or RPE7 (42.9 ± 1.6 vs. 41.2 ± 1.7 rev·min-1), respectively. There were no statistical differences between treatment groups for any other variables, except restlessness rating which was significantly higher (3.5 vs. 2.2; p = 0.03, d = 0.64) for the CAF group compared to PLA. Secondary analysis revealed no statistical differences for any variables between habitual consumers of low (23 ± 20 mg/day) or mod/high (195 ± 93 mg/day) CAF. Our data support previous studies examining CAF in women across different testing modalities and suggest that regardless of habitual CAF consumption, females might require higher doses of CAF to replicate subjective and physiological responses commonly observed using similar RPE production protocols in male participants. These findings support the need for additional investigations into female physiological and perceptual responses following CAF ingestion

    On global-local artificial neural networks for function approximation

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    We present a hybrid radial basis function (RBF) sigmoid neural network with a three-step training algorithm that utilizes both global search and gradient descent training. The algorithm used is intended to identify global features of an input-output relationship before adding local detail to the approximating function. It aims to achieve efficient function approximation through the separate identification of aspects of a relationship that are expressed universally from those that vary only within particular regions of the input space. We test the effectiveness of our method using five regression tasks; four use synthetic datasets while the last problem uses real-world data on the wave overtopping of seawalls. It is shown that the hybrid architecture is often superior to architectures containing neurons of a single type in several ways: lower mean square errors are often achievable using fewer hidden neurons and with less need for regularization. Our global-local artificial neural network (GL-ANN) is also seen to compare favorably with both perceptron radial basis net and regression tree derived RBFs. A number of issues concerning the training of GL-ANNs are discussed: the use of regularization, the inclusion of a gradient descent optimization step, the choice of RBF spreads, model selection, and the development of appropriate stopping criteria

    The potential anticancer activities of platinum(II) complexes with tridentate N'N'N' pincer ligands

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    519-530Treatment of cis/trans-[PtCl2(N≡CR)2] 1 (R = CH3 (1a), C2H5 (1b), C6H5 (1c), CH2C6H4(p-CH3) (1d)) with 1,3-diiminoisoindoline 2 gives access to the corresponding symmetrical (1,3,5,7,9-pentaazanona-1,3,6,8-tetraenato) platinum(II) complexes [PtCl{NH=C(R)N=C(C6H4)NC=NC(R)=NH}] 3a-d, in good yields (65–77%). The compounds 3a-d have been characterized by IR, 1H, 13C and DEPT-135 NMR spectroscopies, ESI-MS and elemental analyses. GIAO/DFT studies have been performed to confirm the molecular structure of the platinum(II)-pincer 3d by comparing the experimental and theoretical 1H and 13C NMR chemical shifts, and it has shown good correlations between experimental and calculated chemical shifts for proton and carbon with correlation coefficients of 0.9947 and 0.9968, respectively. Molecular electrostatic potential is used to investigate the nucleophilic or electrophilic regions in the molecule 3d. The antimicrobial activities of compounds 3a-d are determined against different bacterial pathogens and yeasts. No toxicity is recorded against Artemia saline as a test organism for 3a-c, while moderate toxicity is found for 3d at 0.62 µM. Comparable antitumor activities are found for 3a-d against human colon HCT116 and human breast (MCF-7) cancer cell lines. The complexes 3a-d have shown good binding affinities to ct-DNA in the range of 6.00´105 to 8.33´105 and the conducted molecular docking studies suggest an intercalation mode of binding with DNA by the isoindole fragment of the ligands. Overall, this class of tridentate ligands have shown good potential in designing platinum(II) complexes with promising biological and anticancer activities. Moreover, the presence of the side chains on the ligands provides great design flexibility by introducing some chemical and/or physical characteristics

    Effect of Luting Cements On the Bond Strength to Turkom-Cera All-Ceramic Material

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    BACKGROUND: The selection of the appropriate luting cement is a key factor for achieving a strong bond between prepared teeth and dental restorations.AIM: To evaluate the shear bond strength of Zinc phosphate cement Elite, glass ionomer cement Fuji I, resin-modified glass ionomer cement Fuji Plus and resin luting cement Panavia-F to Turkom-Cera all-ceramic material.MATERIALS AND METHODS: Turkom-Cera was used to form discs 10mm in diameter and 3 mm in thickness (n = 40). The ceramic discs were wet ground, air - particle abraded with 50 - μm aluminium oxide particles and randomly divided into four groups (n = 10). The luting cement was bonded to Turkom-Cera discs as per manufacturer instructions. The shear bond strengths were determined using the universal testing machine at a crosshead speed of 0.5 mm/min. The data were analysed using the tests One Way ANOVA, the nonparametric Kruskal - Wallis test and Mann - Whitney Post hoc test.RESULTS: The shear bond strength of the Elite, Fuji I, Fuji Plus and Panavia F groups were: 0.92 ± 0.42, 2.04 ± 0.78, 4.37 ± 1.18, and 16.42 ± 3.38 MPa, respectively. There was the statistically significant difference between the four luting cement tested (p < 0.05).CONCLUSION: the phosphate-containing resin cement Panavia-F exhibited shear bond strength value significantly higher than all materials tested
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