337 research outputs found
Halogen free 1,2,3- and 1,2,4-triazolide based ionic liquids : synthesis and properties
Triazoles have been successfully used as building blocks to create "fully organic" ILs featuring on both sides organic ions, i.e., 1,2,3- or 1,2,4-triazolide anions and 1,2,4-triazolium or imidazolium cations. Glass transition temperatures, densities and viscosities of these ILs were determined. Their electrochemical and thermal stability, and also conductivity, are higher than those for known ILs
Renewable pyridinium ionic liquids from the continuous hydrothermal decarboxylation of furfural-amino acid derived pyridinium zwitterions
Fully renewable pyridinium ionic liquids were synthesised via the hydrothermal decarboxylation of pyridinium zwitterions derived from furfural and amino acids in flow. The functionality of the resulting ionic liquid (IL) can be tuned by choice of different amino acids as well as different natural carboxylic acids as the counterions. A representative member of this new class of ionic liquids was successfully used for the synthesis of ionogels and as a solvent for the Heck coupling
Technology experience café - enabling technology - driven social innovation for an ageing society
Effective technology innovation process management in the context of active healthy ageing has the potential to improve older adults’ quality of life, allowing them to maintain their independence and age in their own homes for longer. But as older adults significantly differ from the general population in technology use and its impact on their quality of life, tools are needed that (1) involve this target group into the innovation process, as well as (2) capture the diverse needs of technology for various stakeholders involved in this process. This paper presents the framework called Technology Experience Café (TEC), developed within the European project SIforAGE, answering exactly this need. Detailed information on the methodology and its implementation in five sites, in four different countries across Europe, focusing on participating stakeholders, general design of the TEC, and used evaluation tools, is provided. Preliminary results show, that (1) the target group’s perception of the TEC as a framework was thoroughly positive and TECs had a positive impact on older adults’ technology related attitudes and (2) that stakeholders’ benefits affiliated with their involvement in the TECs are manifold. Implications and limitations are discussed
Evidence for short range orbital order in paramagnetic insulating (Al,V)_2O_3
The local structure of (Al_0.06V_0.94)_2O_3 in the paramagnetic insulating
(PI) and antiferromagnetically ordered insulating (AFI) phase has been
investigated using hard and soft x-ray absorption techniques. It is shown that:
1) on a local scale, the symmetry of the vanadium sites in both the PI and the
AFI phase is the same; and 2) the vanadium 3d - oxygen 2p hybridization, as
gauged by the oxygen 1s absorption edge, is the same for both phases, but
distinctly different from the paramagnetic metallic phase of pure V_2O_3. These
findings can be understood in the context of a recently proposed model which
relates the long range monoclinic distortion of the antiferromagnetically
ordered state to orbital ordering, if orbital short range order in the PI phase
is assumed. The measured anisotropy of the x-ray absorption spectra is
discussed in relation to spin-polarized density functional calculations.Comment: 8 pages, 5 figure
The surface science of quasicrystals
The surfaces of quasicrystals have been extensively studied since about 1990. In this paper we review work on the structure and morphology of clean surfaces, and their electronic and phonon structure. We also describe progress in adsorption and epitaxy studies. The paper is illustrated throughout with examples from the literature. We offer some reflections on the wider impact of this body of work and anticipate areas for future development.
(Some figures in this article are in colour only in the electronic version
Identifying Appropriate Nursing Home Resources to Reduce Fall-Related Emergency Department Transfers.
OBJECTIVES
To describe potentially avoidable fall-related transfers to the emergency department (ED), and to identify infrastructure, training needs, and resources deemed appropriate for implementation in nursing homes (NHs) to decrease fall-related transfers to EDs.
DESIGN
A multi-method design, including (1) in-depth case review by an expert panel, (2) structured discussion with NH stakeholders, and (3) appropriateness rating.
SETTING AND PARTICIPANTS
Fall-related transfers were identified from the prospective reporting of every unplanned hospital transfer occurring within 21Â months, collected during the INTERCARE study in 11 Swiss NHs.
METHODS
Eighty-one fall-related transfers were rated for avoidability by a 2-round expert panel. NH stakeholders were consulted to discuss key implementable resources for NHs to mitigate potentially avoidable fall-related transfers. A questionnaire composed of 21 contextually adapted resources was sent to a larger group of stakeholders, to rate the appropriateness for implementation in NHs. χ2 tests were used to assess whether avoidability was associated with an ED visit and to describe transfers. The RAND/UCLA method for appropriateness was used to determine appropriate resources.
RESULTS
One of 4 fall-related transfers were rated as potentially avoidable. A positive association was found between an ED visit and a rating of avoidability (χ2 (1, N = 81) = 18.0, P < .001). Fourteen resources, including developing partnerships with outpatient clinics to access imaging services and strengthening geriatric expertise in nursing homes through clinical training and advanced nurse practitioners, were rated as appropriate by NH stakeholders for NH implementation to reduce potentially avoidable fall-related ED transfers.
CONCLUSIONS AND IMPLICATIONS
Access to diagnostic equipment, geriatric expertise, and clinical training is essential to reduce fall-related potentially avoidable transfers from NHs. Implementing and supporting advanced practice nurses or nurses in extended roles provides NH directors, policymakers, and health care institutions with the possibility of re-engineering resources to limit unnecessary transfers, which are detrimental for resident quality of care and costly for the health system
Crossing borders of material science – a new approach of aerogel preparation for electron microscopy
A new method for the embedding and preparation of organic aerogels for electron mciroscopic Analysis like Crosssectioning, Lamella preparation, FIB-Tomography and Transmissio Electron Microscop
Suicide nanoplasmids coding for ribosome-inactivating proteins
Conventional eukaryotic expression plasmids contain a DNA backbone that is dispensable for the cellular expression of the transgene. In order to reduce the vector size, minicircle DNA technology was introduced. A drawback of the minicircle technology are considerable production costs. Nanoplasmids are a relatively new class of mini-DNA constructs that are of tremendous potential for pharmaceutical applications. In this study we have designed novel suicide nanoplasmid constructs coding for plant derived ribosome-inactivating proteins. The suicide-nanoplasmids were formulated with a targeted K(16)-lysine domain, analyzed for size, and characterized by electron microscopy. The anti-proliferative activity of the suicide-nanoplasmids was investigated in vitro by real time microscopy and the expression kinetic was determined using an enhanced green fluorescent protein nanoplasmid variant. In an aggressive in vivo neuroblastoma tumor model, treated mice showed a reduced tumor growth whereby the therapy was well tolerated
Efficient Transparency in Meat Supply Chains with IT-Standards: EPCIS based Tracking & Tracing for Business Partners, Consumers and Authorities
How can the future agri-food business be made more efficient, transparent and safe? This article on a new MIP meat transparency system describes a future system aiming for an efficient transparency in meat supply chains with ITstandards. The shape of the new system will be highlighted on the background of preliminary ICT solutions and the recent developments in the FIspace project. The core of the supply chain wide transparency is built upon the EPCIS standard from GS1 which enables transparency in the cloud for all stakeholders. Not only the prerequisites but also the benefits from using such a standardized solution are explained for the different user groups. The article closes with an outlook to the further improvements and the expanded usage with new funding by the EU
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