Colitis linfoplasmocitaria canina : un hallazgo frecuente en la exploración colonoscópica

En este trabajo se describen los hallazgos clínicos, laboratoriales y colonoscópicos de la colitis linfoplasmocitaria canina, aparte de tratar los aspectos más relevantes sobre su etiopatogenia y diagnóstico, para describir finalmente las pautas de tratamiento del proceso

Anticuerpos antiespermatozoide en la infertilidad

52 infertil couples were studied by means of the Kibrick macro-aggutination test for circulating anti-spermatozoa antibodies. 33 of them consulted for primary infertility (63.6%) and 19 (36.5%) for secundary infertility, 46.1% of the females had antibodies against spermatozoa with titers ranging from 1:16 to 1:128; only 3.8% from de control group had such antibodies. The frecuency of circulating antibodies was higher for the group of primary infertility (51.5%) than for the group of secundary intertility (36.8%). Only 12 men from the 52 couples studied had circulating antiespermatozoa antibodies with titers equal or less than 1:16; no relation was found between these antibodies and the spermatogram. No significant relation was found between gynecological and obstetric antecedents and circulating anti-spermatozoa antibodies.Utilizando la técnica de macro-aglutinación en gelatina propuesta por Kibrick, se estudio la presencia de anticuerpos antiespermatozoide en parejas infértiles. De 52 parejas, 33 consultaron por infertilidad primaria (63.6%) y 19 por secundaria (36.5%). El 46.1% de todas estas mujeres presentaron anticuerpos circulantes a títulos de 136 a 1:128, contra solo 3.8% en el grupo control. La frecuencia de anticuerpos circulantes fue mayor (51.5%) en el grupo de mujeres consultantes por infertilidad primaria que en aquellas que lo hicieron por infertilidad secundaria (36.8.). Solo 12 hombres dentro del grupo estudiado, presentaron anticuerpos a títulos menores o iguales a 1:16; no hubo en ellos correlación ninguna con la calidad de los espermatozoides. No se encontró ninguna relación entre la patología gineco-obstétrica y la presencia de los anticuerpos circulantes

Factors affecting nectar sugar composition in chiropterophilic plants

AbstractMost pollinators prefer the sugars present in the nectar they consume, so it has been hypothesized that they have molded nectar trait evolution. However, nectar-feeding bats do not exhibit preferences for the sugars present in their diet. We analyzed the role that biochemical and ecological factors could play in shaping the nectar traits of chiropterophilic plants. We studied nectar traits and flower production in 49 plant species. We evaluated the relationship between nectar concentration and sugar composition using phylogenetically independent contrasts and if nectar traits were related to flower production using a Manova. We found that 42 species produced high hexoses nectars, and 7 species produced sucrose rich nectars. Phylogenetically independent contrasts showed that nectar concentration was negatively related to glucose content, positively related to fructose content, and was not related to sucrose content. A negative relationship was found from glucose and fructose contents to sucrose content, and glucose content was negatively related to fructose content. Finally, we did not found any relationship between nectar traits and the plants’ flowering strategies. We conclude that bat physiology and the relative low evolutionary time of the interaction between plants and bats may determine the lack of pattern in the nectar characteristics of chiropterophilic plants

SEOM clinical guidelines in early stage breast cancer (2018)

Breast cancer is the most common cancer in women in our country and it is usually diagnosed in the early and potentially curable stages. Nevertheless, around 20–30% of patients will relapse despite appropriate locoregional and systemic therapies. A better knowledge of this disease is improving our ability to select the most appropriate therapy for each patient with a recent diagnosis of an early stage breast cancer, minimizing unnecessary toxicities and improving long-term efficacy

Surgical Intervention for Phlegmasia Cerulea Dolens in a 61-Year-Old Cancer Patient

Phlegmasia cerulea dolens, a rare and potentially fatal complication of acute deep vein thrombosis, is characterized by substantial edema, intense pain, and cyanosis. Phlegmasia cerulea dolens may compromise limb perfusion and lead to acute ischemia, gangrene, amputation, and death. We present the case of a 61-year-old woman with a history of breast cancer who had signs and symptoms of phlegmasia cerulea dolens in her left leg. She was treated promptly with open surgical thrombectomy and sequential distal compression with use of an Esmarch bandage to ensure complete thrombus extraction. These techniques restored venous flow and saved her leg. Open surgical thrombectomy should be considered in the presence of limb-threatening acute deep vein thrombosis presenting as phlegmasia cerulea dolens

Semiconductor thin films by chemical bath deposition for solar energy related applications.

In this paper we present the basic concepts underlying the chemical bath deposition technique and the recipes developed in our laboratory during the past ten years for the deposition of good-quality thin films of CdS, CdSe, ZnS, ZnSe, PbS, SnS, Bi2 S 3 , Bi2 Se3 , Sb2 S 3 , CuS, CuSe, etc. Typical growth curves, and optical and electrical properties of these films are presented. The effect of annealing the films in air on their structure and composition and on the electrical properties is notable: CdS and ZnS films become conductive through a partial conversion to oxide phase; CdSe becomes photosensitive, SnS converts to SnO2 , etc. The use of precipitates formed during deposition for screen printing and sintering, in polymer composites and as a source for vapor-phase deposition is presented. Some examples of the application of the films in solar energy related work are presented

Hacia el manejo de una herramienta por un robot NAO usando programación por demostración

Programming by demonstration is a technique where, contrary to detailed programming, the robot learns from one or several demonstrations of the execution of the task by a human or another robot. A technique which allows a humanoid robot, take a tool to the head of a screw, following a similar trajectory than demonstrated trajectory by a human being, is presented. The technique also allows variations in location and orientation in the screw head. This is achieved thanks to the use of machine vision techniques and probabilistic models estimated from the demonstrated trajectories. Image processing consists of color space segmentation, and interest point’s selection in the screw head to calculate its position and orientation. The required trajectory in the presence of variations is generated using parameterized Gaussian mixture models in the task. With the above, the new required trajectories are generated in accordance to the variations. The system operation is presented through the illustration of the new trajectories, and pictures of the robot following these trajectories. Despite some limitations of the robotic platform used, acceptable results were achieved. La programación por demostración es una técnica, donde, al contrario de la programación detallada que convencionalmente se hace al robot, éste aprende a partir de una o varias demostraciones por parte de un humano u otro robot. Se presenta una técnica que permite a un robot humanoide, llevar una herramienta hasta la cabeza de un tornillo, siguiendo una trayectoria similar a las trayectorias demostradas por un ser humano. Además, permite variaciones en la ubicación y orientación de la cabeza del tornillo. Esto se logra gracias al uso de técnicas de visión de máquina y de modelos probabilísticos estimados a partir de las trayectorias de las demostraciones. El procesamiento de la imagen consistió en la segmentación en el espacio de color, la selección de puntos de interés de la cabeza del tornillo y a partir de estos el cálculo de su posición y orientación. La trayectoria que se requiere ante las variaciones, se genera usando la técnica de modelo de mezclas de Gaussianas parametrizado en la tarea. A través de gráficas de las nuevas trayectorias e imágenes de la secuencia del robot ejecutando estas trayectorias, se muestra el funcionamiento de la técnica. Pese a algunas limitaciones de la plataforma robótica utilizada, se lograron resultados aceptables

Towards tool handling by a NAO robot using programming by demonstration

La programación por demostración es una técnica, donde, al contrario de la programación detallada que convencionalmente se hace al robot, éste aprende a partir de una o varias demostraciones por parte de un humano u otro robot. Se presenta una técnica que permite a un robot humanoide, llevar una herramienta hasta la cabeza de un tornillo, siguiendo una trayectoria similar a las trayectorias demostradas por un ser humano. Además, permite variaciones en la ubicación y orientación de la cabeza del tornillo. Esto se logra gracias al uso de técnicas de visión de máquina y de modelos probabilísticos estimados a partir de las trayectorias de las demostraciones. El procesamiento de la imagen consistió en la segmentación en el espacio de color, la selección de puntos de interés de la cabeza del tornillo y a partir de estos el cálculo de su posición y orientación. La trayectoria que se requiere ante las variaciones, se genera usando la técnica de modelo de mezclas de Gaussianas parametrizado en la tarea. A través de gráficas de las nuevas trayectorias e imágenes de la secuencia del robot ejecutando estas trayectorias, se muestra el funcionamiento de la técnica. Pese a algunas limitaciones de la plataforma robótica utilizada, se lograron resultados aceptables.Programming by demonstration is a technique where, contrary to detailed programming, the robot learns from one or several demonstrations of the execution of the task by a human or another robot. A technique which allows a humanoid robot, take a tool to the head of a screw, following a similar trajectory than demonstrated trajectory by a human being, is presented. The technique also allows variations in location and orientation in the screw head. This is achieved thanks to the use of machine vision techniques and probabilistic models estimated from the demonstrated trajectories. Image processing consists of color space segmentation, and interest point’s selection in the screw head to calculate its position and orientation. The required trajectory in the presence of variations is generated using parameterized Gaussian mixture models in the task. With the above, the new required trajectories are generated in accordance to the variations. The system operation is presented through the illustration of the new trajectories, and pictures of the robot following these trajectories. Despite some limitations of the robotic platform used, acceptable results were achieved.

Recommendations by the Spanish Society of Hospital Pharmacy, the Spanish Society of Oncology Nursing and the Spanish Society of Medical Oncology for the safe management of antineoplastic medication in cancer patients

Aim: To define recommendations that permit safe management of antineoplastic medication, minimise medication errors and improve the safety of cancer patients undergoing treatment. Methods: By reviewing the literature and consulting the websites of various health organisations and agencies, an expert committee from the Spanish Society of Hospital Pharmacy and the Spanish Society of Medical Oncology defined a set of safe practices covering all stages of providing cancer therapy to patients. The Spanish Society of Oncology Nursing revised and endorsed the final list. Results: In total, 68 recommendations arranged in five sections were defined. They include issues concerning the training of health professionals, the technological resources needed, treatment planning, informing the patient and his/her family, the processes of prescribing, preparing, dispensing and administering cancer therapy (orally, parenterally or intrathecally), assessing patient adherence and treatment toxicity. Conclusions: It is essential for healthcare establishments to implement specific measures designed to prevent medication errors, in order to ensure the safety of cancer patients treated with antineoplastic medication

Congenital leptin deficiency and leptin gene missense mutation found in two colombian sisters with severe obesity

Background: Congenital leptin deficiency is a recessive genetic disorder associated with severe early-onset obesity. It is caused by mutations in the leptin (LEP) gene, which encodes the protein product leptin. These mutations may cause nonsense-mediated mRNA decay, defective secretion or the phenomenon of biologically inactive leptin, but typically lead to an absence of circulating leptin, resulting in a rare type of monogenic extreme obesity with intense hyperphagia, and serious metabolic abnormalities. Methods: We present two severely obese sisters from Colombia, members of the same lineal consanguinity. Their serum leptin was measured by MicroELISA. DNA sequencing was performed on MiSeq equipment (Illumina) of a next-generation sequencing (NGS) panel involving genes related to severe obesity, including LEP. Results: Direct sequencing of the coding region of LEP gene in the sisters revealed a novel homozygous missense mutation in exon 3 [NM_002303.3], C350G>T [p.C117F]. Detailed information and clinical measurements of these sisters were also collected. Their serum leptin levels were undetectable despite their markedly elevated fat mass. Conclusions: The mutation of LEP, absence of detectable leptin, and the severe obesity found in these sisters provide the first evidence of monogenic leptin deficiency reported in the continents of North and South America. © 2019 by the authors. Licensee MDPI, Basel, Switzerland