267 research outputs found

    Efficient Eddy Current Models for Evaluation of Thin Conductive Coatings on Ferromagnetic Substrates

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    Eddy current testing is widely used to determine physical characteristics of materials and to detect flaws by measurements of the electrical impedance of an eddy current probe. In this paper two analytical models allowing to determine properties of non-magnetic conductive coatings on ferromagnetic conductive substrates, are reported. Operating at a single frequency, two following quantities can be determined: permeability-to-conductivity ratio of the substrate and thickness-conductivity product of the coating [1, 2]. The method was validated using both long solenoids and air core surface coils, and was applied to the evaluation of zinc coatings on steel wires and sheets. The theoretical solutions given for high arguments are compact, and allow fast inversion, respectively around 400 and 10 ms for a pancake surface coil and for a long encircling solenoid. Two series of samples: Ø2.2 mm low carbon steel electro galvanized wires and 0.75–20 mm thick hot dip galvanized sheets, were inspected. Steel sheet samples with artificial coatings, as aluminum foils glued from both sides, were also examined. Experimental data of the coil electrical impedance were compared to those predicted. Agreement between theory and experiment is excellent. The technique developed has an extremely low sensitivity to the substrate conductivity and permeability variations [2]. A DC magnetic field, significantly diminishing the permeability of the substrate, almost does not influence results of the coating thickness determination. The agreement between measured thickness and that obtained by other methods is excellent. The accuracy of the thickness determination typically about 1 ÎŒ is obtained

    Effect of a health education intervention on intestinal parasitic infections in Bolivian children

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    Abstract Backgrounds Intestinal parasitic infections (IPI) are a major health issue for children of low- and middle-income countries. Water, sanitation and hygiene (WASH) practices are crucial for preventing IPI. The aim of the study was to evaluate the effects of a school-based health education intervention on handwashing behavior and IPI prevalence in children Methods This is a randomized intervention trial in 8 primary schools in rural communities over the course of 3 school years; preliminary results from the first two years of the trial are here presented. Schools were randomly selected and assigned in a 1:1 ratio to intervention or control (no intervention) groups. For each school year, the intervention included 14 school-based educational sessions and 2 skit events, involving children aged 8-12 years. Knowledge, attitude and practice questionnaire and handwashing at key events was assessed at the beginning and end of each school year. IPI prevalence was assessed with repeated cross-sectional parasitology surveys 12 months apart, involving a minimum of 50 children for each school Results At baseline, no significant differences between intervention and control schools were present in the proportion of children who washed their hands at key events (7.2% vs 9.3%, p = 0.28), in IPI (79.4% vs 75.3%, p = 0.3) and multiple parasitic infections (MPI) prevalences (47.6 vs. 38.6; p = 0.051). At the end of the second year, the percentage of children who washed their hands at key events was significantly higher in the intervention schools (75.4% vs 12.1%, p < 0.001), and the prevalence of IPI and MPI in the intervention schools were respectively about 25% and 15% lower than in the control schools (respectively, 42.9% vs 67.8%, p < 0.001; 16.1% vs 31.6%, p < 0.001) Conclusions A school-based health education intervention could achieve significant changes in hand-washing behaviors and reduction in the prevalence of IPI in children. The third year survey results are needed to confirm these findings Key messages An health education intervention on water, sanitation and hygiene (WASH) practices can reduce the risk of IPI infection in children. An health education intervention on water, sanitation and hygiene (WASH) practices could be configured as a sustainable long-term approach to intestinal parasitic infections control in children

    Public Value Capture of Increasing Property Values across Europe

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    Public value capture is an essential phenomenon to improve the refinancing of public infrastructure and secure the necessary budget for other important duties like education, health and social care. For this reason, smart tools are needed for a successful implementation. This book provides an overview and discussion of instruments and practices in 29 European countries

    Death kinetics of Escherichia coli in goat milk and Bacillus licheniformis in cloudberry jam treated by ohmic heating

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    In recent years, the world’s food industry has focused increasing attention on electrical techniques of food processing. Ohmic heating is one of these techniques that can be considered as a high temperature short time and a purely bulk heating method, having potential applications in processes such as blanching, evaporation and pasteurization in the food industry. However such technology would have to assure the microbiological safety obtained by the conventional cooking methods. Concerning this, the influence of heat treatment by ohmic and conventional technology on death kinetic parameters (D and z values) of Escherichia coli ATCCÂź 25922 was studied in goat milk. In ohmic treatment lower D values were obtained (D60ÂșC = 4.2 min, D63ÂșC = 1.9 min, D65ÂșC = 0.86 min) as compared to conventional treatment (D63ÂșC = 3.9 min, D65ÂșC = 3.5, D67ÂșC = 2.8 min, D75ÂșC = 1.5 min). The increase of temperature required for a ten fold decrease in D value was also lower in the ohmic inactivation (z = 8.4 ÂșC) comparing with the conventional inactivation (z = 23.1 ÂșC). The death kinetics for Bacillus licheniformis ATCCÂź 14580 spores in cloudberry jam were also studied under both types of heat inactivation (ohmic and conventional) and similar conclusions were drawn for the D values; lower D values were also obtained for ohmic treatment (D70ÂșC = 57.1 min, D75ÂșC = 25.2 min, D80ÂșC = 7.2 min) as compared to conventional treatment (D70ÂșC = 85.3 min, D75ÂșC = 51.0, D80ÂșC = 18.1 min, D85ÂșC = 6.0 min, D90ÂșC = 1.6 min). However, between the z values obtained for those treatments (z ohmic = 11.1 ÂșC and z conventional = 11.4 ÂșC) the differences were not significant. In general the results of present work indicate that the ohmic heating provides quicker death kinetics. This opens the perspective for shorter, less aggressive treatments

    Incremental residential densification and urban spatial justice: The case of England between 2001 and 2011

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    Study of the relation between urban density and social equity has been based mostly upon comparative analysis at the city level. It therefore fails to address variations in intra-urban experience and sheds no light on the process of urban densification. Incremental residential development is particularly poorly recorded and under-researched, yet cumulatively it makes a substantial contribution to the supply of dwellings. The article presents a detailed examination of this form of development in England between 2001 and 2011, and considers its impact on urban spatial justice. We find that the incidence of soft residential densification was very uneven. It had disproportionately large effects on neighbourhoods that were already densely developed and that were characterised by lower income households with access to relatively little residential space. It thus contributed to an increase in the level of inequality in the distribution of residential space, increasing socio-spatial injustice

    Global birth defects app: An innovative tool for describing and coding congenital anomalies at birth in low resource settings

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    BACKGROUND: Surveillance programs in low- and middle-income countries (LMICs) have difficulty in obtaining accurate information about congenital anomalies. METHODS: As part of the ZikaPLAN project, an International Committee developed an app for the description and coding of congenital anomalies that are externally visible at birth, for use in low resource settings. The “basic” version of the app was designed for a basic clinical setting and to overcome language and terminology barriers by providing diagrams and photos, sourced mainly from international Birth Defects Atlases. The “surveillance” version additionally allows recording of limited pseudonymized data relevant to diagnosis, which can be uploaded to a secure server, and downloaded by the surveillance program data center. RESULTS: The app contains 98 (88 major and 10 minor) externally visible anomalies and 12 syndromes (including congenital Zika syndrome), with definitions and International Classification of Disease v10 -based code. It also contains newborn examination videos and links to further resources. The user taps a region of the body, then selects among a range of images to choose the congenital anomaly that best resembles what they observe, with guidance regarding similar congenital anomalies. The “basic” version of the app has been reviewed by experts and made available on the Apple and Google Play stores. Since its launch in November 2019, it has been downloaded in 39 countries. The "surveillance” version is currently being field-tested. CONCLUSION: The global birth defects app is a mHealth tool that can help in developing congenital anomaly surveillance in low resource settings to support prevention and care

    Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians

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    Copyright: Copyright 2008 Elsevier B.V., All rights reserved.The associations of the adiponectin (APM1) gene with parameters of the metabolic syndrome are inconsistent. We performed a systematic investigation based on fine-mapped single nucleotide polymorphisms (SNPs) highlighting the genetic architecture and their role in modulating adiponectin plasma concentrations in a particularly healthy population of 1,727 Caucasians avoiding secondary effects from disease processes. Genotyping 53 SNPs (average spacing of 0.7 kb) in the APM1 gene region in 81 Caucasians revealed a two-block linkage disequilibrium (LD) structure and enabled comprehensive tag SNP selection. We found particularly strong associations with adiponectin concentrations for 11 of the 15 tag SNPs in the 1,727 subjects (five P values <0.0001). Haplotype analysis provided a thorough differentiation of adiponectin concentrations with 9 of 17 haplotypes showing significant associations (three P values <0.0001). No significant association was found for any SNP with the parameters of the metabolic syndrome. We observed a two-block LD structure of APM1 pointing toward at least two independent association signals, one including the promoter SNPs and a second spanning the relevant exons. Our data on a large number of healthy subjects suggest a clear modulation of adiponectin concentrations by variants of APM1, which are not merely a concomitant effect in the course of type 2 diabetes or coronary artery disease.publishersversionPeer reviewe

    Air–liquid interface cultures enhance the oxygen supply and trigger the structural and functional differentiation of intestinal porcine epithelial cells (IPEC)

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    The specific function of the epithelium as critical barrier between the intestinal lumen and the organism’s internal microenvironment is reflected by permanent maintenance of intercellular junctions and cellular polarity. The intestinal epithelial cells are responsible for absorption of nutritional components, facing mechanical stress and a changing oxygen supplementation via blood stream. Oxygen itself can regulate the barrier and the absorptive function of the epithelium. Therefore, we compared the dish cell culture, the transwell-like membrane culture and the oxygen enriched air–liquid interface (ALI) culture. We demonstrated strong influence of the different culture conditions on morphology and function of intestinal porcine epithelial cell lines in vitro. ALI culture resulted in a significant increase in cell number, epithelial cell layer thickness and expression as well as apical localisation of the microvilli-associated protein villin. Remarkable similarities regarding the morphological parameters were observed between ALI cultures and intestinal epithelial cells in vivo. Furthermore, the functional analysis of protein uptake and degradation by the epithelial cells demonstrated the necessity of sufficient oxygen supply as achieved in ALI cultures. Our study is the first report providing marked evidence that optimised oxygen supply using ALI cultures directly affects the morphological differentiation and functional properties of intestinal epithelial cells in vitro
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