Variability monitoring of the hydroxyl maser emission in G12.889+0.489

Through a series of observations with the Australia Telescope Compact Array we have monitored the variability of ground-state hydroxyl maser emission from G12.889+0.489 in all four Stokes polarisation products. These observations were motivated by the known periodicity in the associated 6.7-GHz methanol maser emission. A total of 27 epochs of observations were made over 16 months. No emission was seen from either the 1612 or 1720 MHz satellite line transitions (to a typical five sigma upper limit of 0.2 Jy). The peak flux densities of the 1665 and 1667 MHz emission were observed to vary at a level of ~20% (with the exception of one epoch which dropped by <40%). There was no distinct flaring activity at any epoch, but there was a weak indication of periodic variability, with a period and phase of minimum emission similar to that of methanol. There is no significant variation in the polarised properties of the hydroxyl, with Stokes Q and U flux densities varying in accord with the Stokes I intensity (linear polarisation, P, varying by <20%) and the right and left circularly polarised components varying by <33% at 1665-MHz and <38% at 1667-MHz. These observations are the first monitoring observations of the hydroxyl maser emission from G12.889+0.489.Comment: 7 pages, 6 figures, accepted for publication in MNRA

Forensic investigation of microtraces on an item of Dutch eighteenth century clothing in the Rijksmuseum collection

Most garments in museum collections have belonged to people of high societal status. Clothing of the common people, however, has rarely been preserved. Because of this, the conservation of such rare items is of special importance. The current study focuses on such an object from the Rijksmuseum collection; a pair of eighteenth century breeches that were retrieved from an anonymous grave on Spitsbergen. As these breeches contain several unidentified materials, it is unclear how best to conduct the conservation of the object. The identification of trace material plays a key role within criminal law and therefore, it is hypothesized that a forensic approach could provide a suitable framework within this case of cultural heritage as well. After forensic examination, trace material was analyzed using a microscopy-based approach and was found to be mainly of biological origin. Energy-dispersive X-ray (EDX) and Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) spectroscopy indicated the presence of human skin remains. It was concluded that a modern forensic approach can successfully be applied to a historical object within cultural heritage and can assist decision-making regarding possible future conservation of the object. The systematic application of the forensic methodology was found to be appropriate with little to no modification to classify and identify trace materials, but further improvements could be made. The current work should be seen as a starting point that allows for more questions regarding museum objects to be answered in a forensic manner, including aspects such as authenticity, the chain of custody, the context, original use and object conservation

12.2-GHz methanol maser MMB follow-up catalogue - I. Longitude range 330 to 10 degrees

We present a catalogue of 12.2-GHz methanol masers detected towards 6.7-GHz methanol masers observed in the unbiased Methanol Multibeam (MMB) survey in the longitude range 330\circ (through 360\circ) to 10\circ. This is the first portion of the catalogue which, when complete, will encompass all of the MMB detections. We report the detection of 184 12.2-GHz sources towards 400 6.7-GHz methanol maser targets, equating to a detection rate of 46 per cent. Of the 184 12.2-GHz detections, 117 are reported here for the first time. We draw attention to a number of 'special' sources, particularly those with emission at 12.2-GHz stronger than their 6.7-GHz counterpart and conclude that these unusual sources are not associated with a specific evolutionary stage.Comment: accepted to MNRAS 21 Dec 201

A Strong Jet Signature in the Late-Time Lightcurve of GW170817

We present new 0.6-10 GHz observations of the binary neutron star merger GW170817 covering the period up to 300 days post-merger, taken with the Karl G. Jansky Very Large Array, the Australia Telescope Compact Array, the Giant Metrewave Radio Telescope and the MeerKAT telescope. We use these data to precisely characterize the decay phase of the late-time radio light curve. We find that the temporal decay is consistent with a power-law slope of t^-2.2, and that the transition between the power-law rise and decay is relatively sharp. Such a slope cannot be produced by a quasi-isotropic (cocoon-dominated) outflow, but is instead the classic signature of a relativistic jet. This provides strong observational evidence that GW170817 produced a successful jet, and directly demonstrates the link between binary neutron star mergers and short-hard GRBs. Using simple analytical arguments, we derive constraints on the geometry and the jet opening angle of GW170817. These results are consistent with those from our companion Very Long Baseline Interferometry (VLBI) paper, reporting superluminal motion in GW170817.Comment: 11 pages, 3 figures, 3 tables. Accepted for publication in ApJ Letter

Identification of guanine nucleotide exchange factors that increase Cdc42 activity in primary human endothelial cells

The Rho GTPase family is involved in actin dynamics and regulates the barrier function of the endothelium. One of the main barrier-promoting Rho GTPases is Cdc42, also known as cell division control protein 42 homolog. Currently, regulation of Cdc42-based signalling networks in endothelial cells (ECs) lack molecular details. To examine these, we focused on a subset of 15 Rho guanine nucleotide exchange factors (GEFs), which are expressed in the endothelium. By performing single cell FRET measurements with Rho GTPase biosensors in primary human ECs, we monitored GEF efficiency towards Cdc42 and Rac1. A new, single cell-based analysis was developed and used to enable the quantitative comparison of cellular activities of the overexpressed full-length GEFs. Our data reveal GEF dependent activation of Cdc42, with the most efficient Cdc42 activation induced by PLEKHG2, FGD1, PLEKHG1 and PREX1 and the highest selectivity for FGD1. Additionally, we generated truncated GEF constructs that comprise only the catalytic dbl homology (DH) domain or together with the adjacent pleckstrin homology domain (DHPH). The DH domain by itself did not activate Cdc42, whereas the DHPH domain of ITSN1, ITSN2 and PLEKHG1 showed activity towards Cdc42. Together, our study characterized endothelial GEFs that may directly or indirectly activate Cdc42, which will be of great value for the field of vascular biology

How do methanol masers manage to appear in the youngest star vicinities and isolated molecular clumps?

General characteristics of methanol (CH3OH) maser emission are summarized. It is shown that methanol maser sources are concentrated in the spiral arms. Most of the methanol maser sources from the Perseus arm are associated with embedded stellar clusters and a considerable portion is situated close to compact HII regions. Almost 1/3 of the Perseus Arm sources lie at the edges of optically identified HII regions which means that massive star formation in the Perseus Arm is to a great extent triggered by local phenomena. A multiline analysis of the methanol masers allows us to determine the physical parameters in the regions of maser formation. Maser modelling shows that class II methanol masers can be pumped by the radiation of the warm dust as well as by free-free emission of a hypercompact region hcHII with a turnover frequency exceeding 100 GHz. Methanol masers of both classes can reside in the vicinity of hcHIIs. Modelling shows that periodic changes of maser fluxes can be reproduced by variations of the dust temperature by a few percent which may be caused by variations in the brightness of the central young stellar object reflecting the character of the accretion process. Sensitive observations have shown that the masers with low flux densities can still have considerable amplification factors. The analysis of class I maser surveys allows us to identify four distinct regimes that differ by the series of their brightest lines.Comment: 8 pages, 4 figures, invited presentation at IAU242 "Astrophysical Masers and their environments

Athletes treated for inguinal-related groin pain by endoscopic totally extraperitoneal (TEP) repair:long-term benefits of a prospective cohort

Purpose: Inguinal-related groin pain (IRGP) in athletes is a multifactorial condition, posing a therapeutic challenge. If conservative treatment fails, totally extraperitoneal (TEP) repair is effective in pain relief. Because there are only few long-term follow-up results available, this study was designed to evaluate effectiveness of TEP repair in IRGP-patients years after the initial procedure. Methods: Patients enrolled in the original, prospective cohort study (TEP-ID-study) were subjected to two telephone questionnaires. The TEP-ID-study demonstrated favorable outcomes after TEP repair for IRGP-patients after a median follow-up of 19 months. The questionnaires in the current study assessed different aspects, including, but not limited to pain, recurrence, new groin-related symptoms and physical functioning measured by the Copenhagen Hip and Groin Outcome Score (HAGOS). The primary outcome was pain during exercise on the numeric rating scale (NRS) at very long-term follow-up.Results: Out of 32 male participants in the TEP-ID-study, 28 patients (88%) were available with a median follow-up of 83 months (range: 69–95). Seventy-five percent of athletes were pain free during exercise (p &lt; 0.001). At 83 months follow-up, a median NRS of 0 was observed during exercise (IQR 0–2), which was significantly lower compared to earlier scores (p &lt;0.01). Ten patients (36%) mentioned subjective recurrence of complaints, however, physical functioning improved on all HAGOS subscales (p &lt;0.05).Conclusion:This study demonstrates the safety and effectivity of TEP repair in a prospective cohort of IRGP-athletes, for whom conservative treatment had failed, with a follow-up period of over 80 months.</p

VLBI study of maser kinematics in high-mass SFRs. II. G23.01-0.41

The present paper focuses on the high-mass star-forming region G23.01-0.41. Methods: Using the VLBA and the EVN arrays, we conducted phase-referenced observations of the three most powerful maser species in G23.01-0.41: H2O at 22.2 GHz (4 epochs), CH3OH at 6.7 GHz (3 epochs), and OH at 1.665 GHz (1 epoch). In addition, we performed high-resolution (> 0".1), high-sensitivity (< 0.1 mJy) VLA observations of the radio continuum emission from the HMC at 1.3 and 3.6 cm. Results: We have detected H2O, CH3OH, and OH maser emission clustered within 2000 AU from the center of a flattened HMC, oriented SE-NW, from which emerges a massive 12CO outflow, elongated NE-SW, extended up to the pc-scale. Although the three maser species show a clearly different spatial and velocity distribution and sample distinct environments around the massive YSO, the spatial symmetry and velocity field of each maser specie can be explained in terms of expansion from a common center, which possibly denotes the position of the YSO driving the maser motion. Water masers trace both a fast shock (up to 50 km/s) closer to the YSO, powered by a wide-angle wind, and a slower (20 km/s) bipolar jet, at the base of the large-scale outflow. Since the compact free-free emission is found offset from the putative location of the YSO along a direction consistent with that of the maser jet axis, we interpret the radio continuum in terms of a thermal jet. The velocity field of methanol masers can be explained in terms of a composition of slow (4 km/s in amplitude) motions of radial expansion and rotation about an axis approximately parallel to the maser jet. Finally, the distribution of line of sight velocities of the hydroxyl masers suggests that they can trace gas less dense (n(H2) < 10^6 cm^-3) and more distant from the YSO than that traced by the water and methanol masers, which is expanding toward the observer. (Abridged)Comment: 23 pages, 8 figures, 4 tables, accepted by Astronomy and Astrophysic

12.2-GHz methanol maser MMB follow-up catalogue - II. Longitude range 186 to 330 degrees

We present the second portion of a catalogue of 12.2-GHz methanol masers detected towards 6.7-GHz methanol masers observed in the unbiased Methanol Multibeam (MMB) Survey. Using the Parkes radio telescope we have targeted all 207 6.7-GHz methanol masers in the longitude range 186 to 330 degrees for 12.2-GHz counterparts. We report the detection of 83 12.2-GHz methanol masers, and one additional source which we suspect is thermal emission, equating to a detection rate of 40 per cent. Of the 83 maser detections, 39 are reported here for the first time. We discuss source properties, including variability and highlight a number of unusual sources. We present a list of 45 candidates that are likely to harbor methanol masers in the 107.0-GHz transition.Comment: Accepted MNRAS 19 July 201

De effecten van mechanische kokkelvisserij op de benthische macrofauna en hun habitat; eindverslag EVA II (evaluatie schelpdiervisserij tweede fase); deelproject C1/3

Dit rapport beschrijft de resultaten van onderzoek aan de effecten van mechanische kokkelvisserij op kokkelbanken in de Nederlandse Waddenzee. Veldwerk werd verricht in het voorjaar van 1999 en het voorjaar van 2000, op 139 verschillende kokkelbanken, verspreid over de hele Nederlandse Waddenzee. Een deel van deze banken lag in de zogenaamde gesloten gebieden (voor schelpdiervisserij), waardoor er een vergelijking kon worden gemaakt tussen deze gebieden en de rest van de Waddenzee, waar schelpdiervisserij was toegestaan, waarbij steeds gecorrigeerd werd voor verschillen in sediment en droogligtijd van de banken. De kokkels zelf bleken een invloed te hebben op andere wadorganismen. Hiermee rekening houdend met behulp van speciaal voor dit probleem ontwikkelde statistische toetsmethoden, bleek de mechanische kokkelvisserij van op allerlei wadorganismen. Dichtheden aan kokkels, mosselen en nonnetjes waren vaak verlaagd op beviste kokkelbanken en die van sommige wormen verhoogd. De mate van effect verschilde echter aanzienlijk tussen jaren en er kon geen effect van kokkelvisserij op het sediment worden aangetoond. Een nulmeting, die de vergelijking tussen open en gesloten gebieden veel scherper had kunnen toetsen, kon niet worden uitgevoerd omdat dit onderzoek pas plaatsvond nadat er al een jaar gevist was na de relevante broedval, en er sowieso een hele historie van visserij was in de Waddenzee. Een strict experimentele aanpak was wetenschappelijk verkiesbaar geweest, maar was in praktijk niet mogelijk op de schaal van de hele Waddenzee