5,440 research outputs found
Homology and Cohomology of E-infinity Ring Spectra
Every homology or cohomology theory on a category of E-infinity ring spectra
is Topological Andre-Quillen homology or cohomology with appropriate
coefficients. Analogous results hold for the category of A-infinity ring
spectra and for categories of algebras over many other operads
Football Game Program 3 1965
Football Game Program 3 196
Spatial effects on species persistence and implications for biodiversity
Natural ecosystems are characterized by striking diversity of form and
functions and yet exhibit deep symmetries emerging across scales of space, time
and organizational complexity. Species-area relationships and species-abundance
distributions are examples of emerging patterns irrespective of the details of
the underlying ecosystem functions. Here we present empirical and theoretical
evidence for a new macroecological pattern related to the distributions of
local species persistence times, defined as the timespans between local
colonizations and extinctions in a given geographic region. Empirical
distributions pertaining to two different taxa, breeding birds and herbaceous
plants, analyzed in a new framework that accounts for the finiteness of the
observational period, exhibit power-law scaling limited by a cut-off determined
by the rate of emergence of new species. In spite of the differences between
taxa and spatial scales of analysis, the scaling exponents are statistically
indistinguishable from each other and significantly different from those
predicted by existing models. We theoretically investigate how the scaling
features depend on the structure of the spatial interaction network and show
that the empirical scaling exponents are reproduced once a two-dimensional
isotropic texture is used, regardless of the details of the ecological
interactions. The framework developed here also allows to link the cut-off
timescale with the spatial scale of analysis, and the persistence-time
distribution to the species-area relationship. We conclude that the inherent
coherence obtained between spatial and temporal macroecological patterns points
at a seemingly general feature of the dynamical evolution of ecosystems.Comment: 5 pages, 5 figures. Supplementary materials avaliable on
http://www.pnas.org/content/108/11/434
Retrospective survey for sialidase activity in Mycoplasma pneumoniae isolates from cases of community-acquired pneumonia
<p>Abstract</p> <p>Background</p> <p>Sialidase is a well-known virulence factor of other respiratory pathogens, but was only recently documented to occur in some species of <it>Mycoplasma</it>. The sialidase activity expressed can vary quantitatively among strains within a species of mycoplasma, from undetectable to amounts that correlate positively with strain virulence. Very few isolates of <it>Mycoplasma pneumoniae </it>had ever been examined for sialidase activity, so it was unknown whether sialidase may contribute to diseases involving this species.</p> <p>Findings</p> <p>No sialidase activity was detected by spectrofluorometric assay of 15 laboratory strains and 91 clinical isolates of <it>M. pneumoniae </it>banked over many years from patients having radiologically-confirmed, uncomplicated community-acquired pneumonia.</p> <p>Conclusions</p> <p>The annotated genome of strain M129 (GenBank <ext-link ext-link-id="NC_000912" ext-link-type="gen">NC_000912</ext-link>, <ext-link ext-link-id="ATCC29342" ext-link-type="gen">ATCC 29342</ext-link>), also isolated from a patient with pneumonia, accurately represents the absence of sialidase genes from strains of <it>M. pneumoniae </it>typically associated with uncomplicated community-acquired pneumonia. A possible involvement of sialidase in neurologic or other extra-respiratory manifestations of <it>M. pneumoniae </it>mycoplasmosis remains to be investigated.</p
Arduous implementation: Does the Normalisation Process Model explain why it's so difficult to embed decision support technologies for patients in routine clinical practice
Background: decision support technologies (DSTs, also known as decision aids) help patients and professionals take part in collaborative decision-making processes. Trials have shown favorable impacts on patient knowledge, satisfaction, decisional conflict and confidence. However, they have not become routinely embedded in health care settings. Few studies have approached this issue using a theoretical framework. We explained problems of implementing DSTs using the Normalization Process Model, a conceptual model that focuses attention on how complex interventions become routinely embedded in practice.Methods: the Normalization Process Model was used as the basis of conceptual analysis of the outcomes of previous primary research and reviews. Using a virtual working environment we applied the model and its main concepts to examine: the 'workability' of DSTs in professional-patient interactions; how DSTs affect knowledge relations between their users; how DSTs impact on users' skills and performance; and the impact of DSTs on the allocation of organizational resources.Results: conceptual analysis using the Normalization Process Model provided insight on implementation problems for DSTs in routine settings. Current research focuses mainly on the interactional workability of these technologies, but factors related to divisions of labor and health care, and the organizational contexts in which DSTs are used, are poorly described and understood.Conclusion: the model successfully provided a framework for helping to identify factors that promote and inhibit the implementation of DSTs in healthcare and gave us insights into factors influencing the introduction of new technologies into contexts where negotiations are characterized by asymmetries of power and knowledge. Future research and development on the deployment of DSTs needs to take a more holistic approach and give emphasis to the structural conditions and social norms in which these technologies are enacte
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The impact of extreme events on freshwater ecosystems: executive summary and policy brief
Cancer data and Aboriginal disparities (CanDAD)-developing an Advanced Cancer Data System for Aboriginal people in South Australia: a mixed methods research protocol
Introduction: In Australia, Aboriginal and Torres Strait Islander People carry a greater burden of cancerrelated mortality than non-Aboriginal Australians. The Cancer Data and Aboriginal Disparities Project aims to develop and test an integrated, comprehensive cancer monitoring and surveillance system capable of incorporating epidemiological and narrative data to address disparities and advocate for clinical system change. Methods and analysis: The Advanced Cancer Data System will integrate routinely collected unit record data from the South Australian Population Cancer Registry and a range of other data sources for a retrospective cohort of indigenous people with cancers diagnosed from 1990 to 2010. A randomly drawn non- Aboriginal cohort will be matched by primary cancer site, sex, age and year at diagnosis. Cross-tabulations and regression analyses will examine the extent to which demographic attributes, cancer stage and survival vary between the cohorts. Narratives from Aboriginal people with cancer, their families, carers and service providers will be collected and analysed using patient pathway mapping and thematic analysis. Statements from the narratives will structure both a concept mapping process of rating, sorting and prioritising issues, focusing on issues of importance and feasibility, and the development of a real-time Aboriginal Cancer Measure of Experience for ongoing linkage with epidemiological data in the Advanced Cancer Data System. Aboriginal Community engagement underpins this Project. Ethics and dissemination: The research has been approved by relevant local and national ethics committees. Findings will be disseminated in local and international peer-reviewed journals and conference presentations. In addition, the research will provide data for knowledge translation activities across the partner organisations and feed directly into the Statewide Cancer Control Plan. It will provide a mechanism for monitoring and evaluating the implementation of the recommendations in these documents.Paul Henry Yerrell, David Roder, Margaret Cargo, Rachel Reilly, David Banham, Jasmine May Micklem, Kim Morey, Harold Bundamurra Stewart, Janet Stajic, Michael Norris, Alex Brown, On behalf of the CanDAD Aboriginal Community Reference Group and CanDAD Investigator
The Lantern Vol. 2, No. 2, March 1934
• Fulfillment Through Expression • Ole Man Ennis • Nos Illusions by Philippe Vallee • A Celtic May Day Festival • Dew Drops • Baker Street Fiction • March Winds • Winter Sunset • Book Review: No Second Spring • A Thought • The Cask of Amontillado • Illustrationhttps://digitalcommons.ursinus.edu/lantern/1002/thumbnail.jp
From Davydov solitons to decoherence-free subspaces: self-consistent propagation of coherent-product states
The self-consistent propagation of generalized [coherent-product]
states and of a class of gaussian density matrix generalizations is examined,
at both zero and finite-temperature, for arbitrary interactions between the
localized lattice (electronic or vibronic) excitations and the phonon modes. It
is shown that in all legitimate cases, the evolution of states reduces
to the disentangled evolution of the component states. The
self-consistency conditions for the latter amount to conditions for
decoherence-free propagation, which complement the Davydov soliton
equations in such a way as to lift the nonlinearity of the evolution for the
on-site degrees of freedom. Although it cannot support Davydov solitons, the
coherent-product ansatz does provide a wide class of exact density-matrix
solutions for the joint evolution of the lattice and phonon bath in compatible
systems. Included are solutions for initial states given as a product of a
[largely arbitrary] lattice state and a thermal equilibrium state of the
phonons. It is also shown that external pumping can produce self-consistent
Frohlich-like effects. A few sample cases of coherent, albeit not solitonic,
propagation are briefly discussed.Comment: revtex3, latex2e; 22 pages, no figs.; to appear in Phys.Rev.E
(Nov.2001
All-sky Galactic radiation at 45 MHz and spectral index between 45 and 408 MHz
Aims: We study the Galactic large-scale synchrotron emission by generating a
reliable all-sky spectral index map and temperature map at 45 MHz. Methods: We
use our observations, the published all-sky map at 408 MHz, and a
bibliographical compilation to produce a map corrected for zero-level offset
and extragalactic contribution. Results: We present full sky maps of the
Galactic emission at 45 MHz and the Galactic spectral index between 45 and 408
MHz with an angular resolution of 5\degs. The spectral index varies between 2.1
and 2.7, reaching values below 2.5 at low latitude because of thermal free-free
absorption and its maximum in the zone next to the Northern Spur.Comment: A&A accepte
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