Kurumsal sosyal sorumluluk faaliyetlerinin örgütsel güven üzerindeki etkisinin belirlenmesine yönelik bir araştırma

86 sayfa29 cm. 1 CDÖZETÇalışanların zamanlarının büyük bir bölümünü iş yerlerinde geçirmeleri sebebiyle güven duygusunun oluşumu, önemli bir husus olarak göze çarpmaktadır. Diğer bir deyişle, bireylerin yöneticilerine ve örgütlerine karşı duydukları güvenin yüksekliği, gerek çalışan gerekse örgüt sağlığı bakımıdan kritik bir unsurdur. Giderek önemi artan kurumsal sosyal sorumluluk (KSS) kavramı ise, örgütlerin toplumdan ve doğadan aldıklarını geri verme yükümlülüğünden doğmaktadır. Bu bağlamda örgütlerin kurum içi ve kurum dışı paydaşlara karşı sorumlulukları söz konusudur. Söz konusu iki kavramdan hareketle, bu çalışmanın temel amacı, kurumsal sosyal sorumluluk faaliyetlerinin bütün olarak ve ayrı ayrı örgütsel güven ve boyutları üzerinde anlamlı bir etkisi olup olmadığını tespit etmektir. Araştırma, ilçe belediyesinde çalışan 136 beyaz yaka çalışan ile gerçekleştirilmiştir. Anket tekniği ile toplanan verilere uygulanan regresyon analizi sonucunda kurumsal sosyal sorumluluk faaliyetlerinin örgütsel güven üzerinde anlamlı pozitif bir etkisinin olduğu saptanmıştır.ABSTRACTThe formation of a sense of trust is an important issue when employees spend a large part of their time at work. In other words, the security of the trustof individuals towards their managers and organizations is a critical element both in employees and in our organization. Inceasingly important corporate social responsibility (CRS) is the result of organizations' ability to give back what they have received from society and nature. In this rule, organizations have responsibilities to internal and external stakeholders. Based on these two cohcepts, the main objective of this study is to consider whether there is a significant factor in the holistic and separate organizational trust and focus of corporate social responsibility activities. The recearch was carried out with 136 white collar employees working in the district municipality. Regression analysis based on the data collected by questionnaire technique revealed that sovial reponsibility activities had no significant positive effect on organizational trust

The effect of jet-lag on serum concentrations of thyroid stimulating hormone and prolactin: A case report

Introduction: This case report is about the importance of sleeping status for analysis of thyroid hormone stimulating hormone (TSH) and prolactin (PRL) which arose from discordant results of a patient who was referred for serum TSH and PRL testing within 12-hour period after an intercontinental flight. Case description: An adult male patient was admitted to our laboratory for serum TSH and PRL tests and came back questioning the accuracy of his previous results. Further investigations: A new analysis with a new sample was offered. His new results were not consistent with his previous results. What happened: It was revealed that the night before the first sampling, he travelled back to Turkey from The United States of America and came to testing within 12 hours after the arrival. Discussion: Sleeping status is one of the factors that can affect laboratory results. Intercontinental flights causing jet-lag can alter the secretions of TSH and PRL which are predominantly modulated by thyrotropin-releasing hormone (TRH). Main lesson: Travel history and sleeping status are important factors to be evaluated prior sampling for hormone analysis. Patients must be informed about the importance of sampling timing

Evaluation of Initial Stress Distribution and Displacement Pattern of Craniofacial Structures with 3 Different Rapid Maxillary Expansion Appliance Models: A 3-dimensional Finite Element Analysis

Objective: This study aimed to describe the displacement of anatomical structures and the stress distributions caused by the Hyrax, fan-type, and double-hinged expansion screws via the 3-dimensional (3D) finite element method (FEM).Methods: The 3D FEM was based on the computed tomography data of a 12-year-old patient with a constricted maxilla. The Hyrax model included 1,800,981 tetrahedral elements with 2,758,217 nodes. The fan-type model included 1,787,558 tetrahedral elements with 2,737,358 nodes. The double-hinged model included 1,777,080 tetrahedral elements with 2,722,771 nodes. The von Mises stress distributions after 0.2 mm of expansion and displacement patterns after 5 mm of expansion were evaluated.Results: The highest stress accumulation was observed in the sutura zygomatico maxillaris area with all 3 appliances. An increase in stress was noted at the pterygomaxillary fissure, the medial and lateral pterygoid process of the sphenoid bone, and the nasal areas. The wedge-shaped skeletal opening was observed with all 3 appliances. In the transverse plane, maximum posterior expansion was achieved with the Hyrax appliance, whereas the maximum anterior expansion was observed with the double-hinged appliance. The maxilla moved inferiorly and anteriorly with all the 3 appliances. The greatest inferior displacement of the maxilla was recorded with the Hyrax appliance, whereas anterior maxillary displacement was the greatest with the double-hinged appliance.Conclusion: All the appliances showed similar stress distributions. The use of double-hinged screw caused a slight anterior displacement of point A. The fan-type and double-hinged appliances were shown to be more effective on anterior maxillary constriction, whereas the Hyrax appliance might be chosen for resolving maxillary posterior constriction

Comparison of two different antibiotic regimens for the prophylaxisis of cases with preterm premature rupture of membranes: a randomized clinical trial

Objectives: The aim of the study was to assess the effect of 1 g ampicillin prophylactic dosage whether it is as effective as the dosage of 2 g to prevent maternal and neonatal morbidity in a randomized manner. Materials and methods: One hundred and fourty eight singleton pregnant women with preterm premature rupture of membranes between 21 and 33 weeks of gestation were followed-up during the study period in our institution. We com­pared the efficacy of two different different dosages of ampicillin. The study population was randomized into 2 groups. In the group 1, 1 g of intravenous ampicillin was given every 6 hours. In the group 2, 2 g of intravenous ampicillin was given every 6 hours. Results: There was no significant difference between groups interms of fetal complications (RDS, icterus, mortality, sepsis, transient tachypnea of newborn and the pneumonia), rate of intensive care unit admission, fetal gender, fever, rate of clinical chorioamnionitis, high white blood cell count and the CRP, rate of cases < 30 weeks (p > 0.05). There was a significant differ­ence between the groups for the rate of previous preterm premature rupture of membranes history, steroid administration and the need for tocolysis (p < 0.05). Conclusions: Although antibiotics seems to be innocent, several side effects have been introduced. It is reasonable to use the lowest dosages in shortest period in order to minimize these unwanted effects

Comparison of radon concentrations in soil gas and indoor environment of Afyonkarahisar province

It is well known that radon is the main source of natural radiation exposure to the population. Indoor radon concentrations in an area are affected by ascending radon migration following the convection of groundwater and soil gas along fractures and faults in the bedrock sediments. There are various studies showing that positive radon anomalies in the soil gas are found to coincide with the locations of houses showing the highest concentrations. Moreover, soil gas radon levels and soil permeability are important factors in determining the radon potential of an area, because high permeability enables the increased migration of radon from the soil into houses. Since radon in homes originates mainly from soil gas radon, it is of public interest to study the correlation between soil gas radon and indoor radon in different geographic locations. In the present work, a correlation study was carried in conjunction with radon concentrations in soil gas and indoor environment of Afyonkarahisar Province. The provincial center was assumed to be divided into four regions according to the rock types and tectonic structure to show also the geological structure effect on radon concentrations. The indoor radon concentrations were measured in 74 dwellings using CR-39 passive nuclear track detectors, and the radon concentrations in soil gas were determined in 243 drilled holes using AlphaGUARD detector. The correlation coefficient of 0.97 was obtained between radon concentrations in soil gas and indoor environment of Afyonkarahisar Province.Turkish Atomic Energy Authority Afyon Kocatepe University Science Research Projects Coordination Uni

Diagnosis of comorbid migraine without aura in patients with idiopathic/genetic epilepsy based on the gray zone approach to the International Classification of Headache Disorders 3 criteria

BackgroundMigraine without aura (MwoA) is a very frequent and remarkable comorbidity in patients with idiopathic/genetic epilepsy (I/GE). Frequently in clinical practice, diagnosis of MwoA may be challenging despite the guidance of current diagnostic criteria of the International Classification of Headache Disorders 3 (ICHD-3). In this study, we aimed to disclose the diagnostic gaps in the diagnosis of comorbid MwoA, using a zone concept, in patients with I/GEs with headaches who were diagnosed by an experienced headache expert.MethodsIn this multicenter study including 809 consecutive patients with a diagnosis of I/GE with or without headache, 163 patients who were diagnosed by an experienced headache expert as having a comorbid MwoA were reevaluated. Eligible patients were divided into three subgroups, namely, full diagnosis, zone I, and zone II according to their status of fulfilling the ICHD-3 criteria. A Classification and Regression Tree (CART) analysis was performed to bring out the meaningful predictors when evaluating patients with I/GEs for MwoA comorbidity, using the variables that were significant in the univariate analysis.ResultsLonger headache duration (<4 h) followed by throbbing pain, higher visual analog scale (VAS) scores, increase of pain by physical activity, nausea/vomiting, and photophobia and/or phonophobia are the main distinguishing clinical characteristics of comorbid MwoA in patients with I/GE, for being classified in the full diagnosis group. Despite being not a part of the main ICHD-3 criteria, the presence of associated symptoms mainly osmophobia and also vertigo/dizziness had the distinguishing capability of being classified into zone subgroups. The most common epilepsy syndromes fulfilling full diagnosis criteria (n = 62) in the CART analysis were 48.39% Juvenile myoclonic epilepsy followed by 25.81% epilepsy with generalized tonic-clonic seizures alone.ConclusionLonger headache duration, throbbing pain, increase of pain by physical activity, photophobia and/or phonophobia, presence of vertigo/dizziness, osmophobia, and higher VAS scores are the main supportive associated factors when applying the ICHD-3 criteria for the comorbid MwoA diagnosis in patients with I/GEs. Evaluating these characteristics could be helpful to close the diagnostic gaps in everyday clinical practice and fasten the diagnostic process of comorbid MwoA in patients with I/GEs

Effects of probiotics on the human miRNAs

Yüksek Lisans TeziGiriş: Probiyotikler, "yeterli miktarda tüketildiklerinde konakçıyı olumlu yönde etkileyen canlı mikroorganizmalar" olarak tanımlanır. Probiotiklerin inflamatuvar bağırsak hastalığını önlediği, antimikrobiyal ve anti-kororektal kanser faaliyetler sergilediği gösterilmiştir. Mikro RNA'lar (miRNA'lar), çoğalma, apoptoz ve gelişme gibi temel hücresel süreçleri düzenleyen temel koordinatörler olarak görülen 17-25 nükleotid uzunluğunda, küçük, kodlayıcı olmayan RNA'lardır. İnsan Genom Projesinin tamamlanması, diğer bilimlerde olduğu gibi, beslenme biliminde de en önemli dönüm noktalarından biri olmuştur. Beslenme, gen ekspresyonunda önemlidir ve hastalık önleme üzerindeki genetik çeşitlilikleri etkiler. Dolayısıyla, bu çalışmada gıda takviyesi olarak alınan probiyotiklerin insan miRNA'ları üzerinde etkisi olup olmadığını araştırmak amaçlanmıştır. Gereç ve Yöntem: Çalışma, 18-65 yaş aralığındaki 20 (11 erkek, 9kadın) sağlıklı bireyle gerçekleştirilmiştir. Bireyler 10 gün gıda takviyesi probiyotik kullanmışlardır. Probiyotik kullanmadan önce ve sonraki alınan kan numunelerinden elde edilen plazma, RT-PZR ile analiz edilmiştir. MiR-15, miR-16, miR-29 ve miR-196'nın ekspresyon seviyeleri belirlenmiştir. Bulgular: Bu çalışmada aşağıdaki formül ile, seçilen miRNA'ların ekspresyonunu hesaplamak için bir internal kontrol olarak U6 housekeeping geni kullanılmıştır: ΔCthedef miRNA = Cthedef miRNA - CtU6. Düşük ΔCt değeri, yüksek miRNA seviyesini ve yüksek ΔCt, daha düşük miRNA seviyesini temsil eder. Gruplar arasındaki farkı karşılaştırmak için T-testi kullanılmıştır. 4 miRNA grubu, kat artış oranı ≥ 1.5 olarak tanımlanmıştır ancak t-testine göre miR-196 hariç p> 0.05; miR-15, miR-16 ve miR-29 için p 0.05) miR-15, miR-16 and miR-29 values of p<0.05. Conclusions: While expression levels of miR-15, miR-16, miR-29 and miR-196 are very low in various diseases, especially in cancer; the expression of miR-15, miR-16 miR-29 and miR-196 were found high after using probiotics. Consequently, probiyotics are impacted on miRNA expression levels but further studies are mandatory to a better understand and confirm probiotics effect mechanism on miRNAs

Evaluation of Products Packages Intended The Province Identification at Turkey

Araştırmanın konusu Türkiye'de illerin tanıtımına yönelik ürün ambalajlarının değerlendirilmesidir. Bu araştırmanın amacı, Türkiye'deki illerin ürün ambalajlarının tasarım açısından (kullanım kolaylığı, renk, görsellerin ürün hakkında bilgi vermesi, ürünü koruması, farkedilir nitelikte olması, maliyet, ürün tanıtımı bakımından bölgeye katkısının) incelenmesidir. Araştırmanın modeli betimlemeyi amaçlayan tarama modelidir. Verilerin toplanması için kullanıcılara araştırmacı tarafından hazırlanan ve 10 sorudan oluşan 5'li likert anket uygulanmıştır. Anket soruları grafik tasarım alanında uzman 3 akademisyen ve sektörde çalışan 2 grafik tasarımcı olmak üzere toplamda 5 kişinin görüşü alınarak geliştirilmiştir. Çalışma grubunu T.C. İstanbul Yeni Yüzyıl Üniversite'si Topkapı Dr. Azmi Ofluoğlu Yerleşkesi bünyesinde çalışan akademik personel 70 kişi ve idari personel 50 kişi olmak üzere toplamda 120 kişi oluşturmaktadır. Sonuçların analizi için SPSS programında verilerin aritmetik ortalama ve standart sapma değerleri hesaplanmıştır. Alt amaçların sonucunu almaya yönelik olarak tasarımlarda kullanım kolaylığı, görsel renk ilişkisi, görsellerin ürün hakkında bilgi vermesi, koruma, farkedilir olma, maliyet ve ürün tanıtımı açısından bölgeye katkı sağlama boyutuna ilişkin 7 adet tablo elde edilmiştir. Alt amaçlara yönelik elde edilen 7 adet tablo bulgular ve yorum kısmında yorumlanmıştır. Araştırmanın sonucunda ürün ambalajlarının alt amaçlara uygunluğu saptanmıştır ve önerilerde bulunulmuştur. Kullanım kolaylığı, renk, koruma, görsellerin yeterince bilgi vermesi, tanıtıma katkı sağlaması ve farkedilirlik bakımından kullanılan ambalajlar yeterli bulunmuştur. Kullanıcı görüşleri arasında alt amaçlara yönelik bütün kriterlerin yeterli olması açısından anlamlı farklılık bulunmamakla birlikte sonuçların Konya, İzmir, Bursa, Rize ve Şanlıurfa illerine ait tanıtıcı ürün ambalajlarının lehine olduğu görülmüştür.The research subject involves the evaluation of product packages intended the provinces identification at Turkey. The aim of this research is to analyze, the package that provides the presentation of the product, color, provide information about the products visually, product protection, noticeable quality, package costs, criteria of the province of product packaging at Turkey. In addition, this research aimed to describe the model is a screening model. During this research, there is also applied 10-items 5-options Likert Questionnaire for the users of this data collection. The survey questions graphic design is based on the expert opinion of 3 academicians and a total of 5 people, including 2 graphics designers working in this sector. This study group comprises T.C. Istanbul Yeni Yuzyıl University Topkapı Dr. Azmi Ofluoglu Campus, academic staff has reached 70 participants and administrative staff has reached 50, total 120 participants. For analysis of results, SPSS software program's arithmetical average and standard deviation value calculation feature was used. 7 tables were obtained about ease of use, visual-color relation, giving information about the product, conservation, awareness, cost and contribution to the region in terms of product promotion for the sub purposes. 7 tables obtained for sub-purposes were interpreted in findings and interpretations part. As a result of this research, the suitability of the product packaging determines, and has made suggestions. Ease of use, color, conservation, provide enough visual information, it was determined that likes to contribute to the promotion and packaging of selected terms discoverable. Although there is no significant difference between participants opinion in terms of satisfying all the criteria for sub purposes, It has seen that the results are in favor of introductory products packaging of Konya, Izmir, Bursa, Rize and Sanliurfa provinces

Effect of various citrus rootstocks on plant nutrition elements of Clementine nules mandarin varieties.

TEZ13115Tez (Yüksek Lisans) -- Çukurova Üniversitesi, Adana, 2020.Kaynakça (s. 43-50) var.XV, 51 s. :_res. (bzs. rnk.), tablo ;_29 cm.Bu çalışmada, 10 farklı turunçgil anaçlarının Klemantin nules mandarin çeşidinin bitki besin elementi düzeyleri üzerine etkileri 2017, 2018 ve 2019 yıllarında üç yıl süreyle incelenmiştir. Anaçlarbitki besin elementi üzerine önemli etkilerde bulunmuşlardır. Azot içeriği en yüksek FAO-SRA, C-35 ve FA 5 anaçlarından elde edilmiştir. Carrizo ve Fhlorag 1 anaçları en yüksek Fosfor içeriğine sahip anaçlar olarak tespit edilmiştir. Fhlorag 1 anacı en yüksek potasyum ve demir içeriğine sahip anaç olmuştur. Tuzcu 891 anacı ise kalsiyum ve magnezyum içerikleri bakımından en yüksek değerleri vermiştir. Çinko içeriği en yüksek Volkameriana anacından, mangan en yüksek FA 5 anacından, bakır ise en yüksek FA 517 ve Carrizo sitranjından elde edilmiştir.In this study, the effects of 10 citrus rootstocks on the nutrient levels of the Clemenules clementine mandarin variety were investigated for three consecutive years in 2017,2018 and 2019. Rootstocks significantly effected plant nutrition elements concentrations. The highest nitrogen concentrations were determined in the leaves of Nules clementine grafted on FAO-SRA, C-35 citrange and FA5 rootstocks. The highest phosphorus concentrations were obtained from leaves on Carrizo citrange and Fhlorag 1 rootstocks. Leaves grafted on Fhlorag 1 had the highest potassium and iron concentrations. Calcium and magnesium concentrations were the highest in leaves grafted on Tuzcu 891 sour orange. The highest zinc concentration was determined in the leaves grafted on Volkameriana, the highest manganase on FA5 and the highest cupper concentrations were determined in the leaves of trees grafted on FA517 and Carrizo rootstocks

Nonalkolik Yağlı Karaciğer Hastalığında Fiziksel Aktivite ve Beslenmenin Fibroblast Büyüme Faktörü 21 ve İrisin Üzerine Etkileri

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver diseases. At the present time, the most important treatment of NAFLD is the lifestyle changes, which include diet and physical activity. The purpose of this study is to determine the effects of diet compatible with NAFLD and physical activity on serum irisin and FGF21 levels and some biochemical and anthropometric parameters in non-alcoholic fatty liver disease. A total of 33 subjects (16 males and 17 females) participated in the present study, which were diagnosed with NAFLD. General information, nutrition habits, physical activity status and 24-hour dietary recall were collected through questionnaire and a diet compatible with NAFLD was presciribed individually. A total of 17 subjects (9 males and 8 females) completed the 4 weeks medical nutrition therapy (MNT). At the beginning and at the end of 4 weeks, anthropometric measurements and blood samples were taken from the individuals. In the collected blood samples, serum irisin and FGF21 levels were quantified with commercial ELISA kits. Physical activity records and 2-day food records were collected for 4 weeks. As a result of 4 weeks MNT, body weight, body mass index, waist circumference, neck circumference, body fat ratio, body fat mass, ALT, AST and GGT of males and body weight, body mass index, body fat mass, ALT and AST of females were significantly decreased. At the beginning, FGF21 level was 166,6±91,95 pg/mL in males and 328,6±226,72 pg/mL in females, while serum irisin level was 6,3±2,10 ng/mL in males and 4,3±0,77ng/mL in females. At the end of 4 weeks, serum FGF21 level was 214,7±107,33 pg/mL in males and 244,1±131,21 pg/mL in females, while serum irisin level was 5,2±0,57 ng/mL in males and 4,3±0,77 ng/mL in females. Irisin and FGF21 levels of subjects did not change according to MNT or physical activity status. Further studies are needed to understand the association of irisin and FGF21 with NAFLD.Nonalkolik yağlı karaciğer hastalığı (NAYKH) kronik karaciğer hastalıklarının en yaygın nedenidir ve günümüzde NAYKH’nin en önemli tedavisi diyet ve fiziksel aktiviteyi içeren yaşam tarzı değişikliğidir. Bu çalışmanın amacı non-alkolik yağlı karaciğer hastalığında fiziksel aktivite düzeyinin ve NAYKH ile uyumlu diyetin kanda hastalıkla ilişkili olan bazı biyokimyasal parametrelere, antropometrik ölçümlere ve serum irisin ve fibroblast büyüme faktörü (FGF21) düzeylerine etkisini incelemektir. Çalışmaya NAYKH tanısı almış, 17 kadın ve 16 erkek olmak üzere toplam 33 birey dahil edilmiştir. Bireylerin genel bilgileri, beslenme alışkanlıkları, fiziksel aktivite durumları ve 24 saatlik geriye dönük besin tüketim kayıtları anket yardımıyla alınmış ve sonrasında bireysel olarak NAYKH ile uyumlu diyet planlanmıştır. 4 haftalık tıbbi beslenme tedavisini (TBT) 9 erkek ve 8 kadın olmak üzere toplam 17 kişi tamamlamıştır. Başlangıçta ve 4 hafta sonunda bireylerden antropometrik ölçümleri ve kan örnekleri alınmıştır. Toplanan kan örneklerinde uygun ELISA kitleri yardımıyla irisin ve FGF21 serum proteinleri çalışılmıştır. Bireylerden 4 hafta boyunca, haftada 2 gün besin tüketim kaydı ve fiziksel aktivite kaydı alınmıştır. 4 haftalık TBT sonucunda erkeklerin vücut ağırlığı, beden kütle indeksi, bel çevresi, boyun çevresi, vücut yağ oranı, vücut yağ miktarı, ALT, AST ve GGT değerleri, kadınların ise, vücut ağırlığı, beden kütle indeksi, vücut yağ miktarı, ALT ve AST değerleri anlamlı olarak azalmıştır. Başlangıçta serum irisin düzeyi erkeklerde 6,3±2,10 ng/mL, kadınlarda 4,3±0,77 ng/mL iken, FGF21 düzeyi erkeklerde 166,6±91,95 pg/mL kadınlarda 328,6±226,72 pg/mL’dir. 4 hafta sonunda ise, serum irisin düzeyi erkeklerde 5,2±0,57 ng/mL, kadınlarda 4,3±0,77 ng/mL, FGF21 düzeyi erkeklerde 214,7±107,33 pg/mL kadınlarda 244,1±131,21 pg/mL olarak bulunmuştur. Bireylerin irisin ve FGF21 düzeyleri tıbbi beslenme tedavisine veya fiziksel aktivite durumuna göre değişiklik göstermemiştir. İrisin ve FGF21 gibi son yıllarda çalışılmaya başlanan moleküllerin NAYKH ile ilişkisinin anlaşılması için daha fazla çalışma gerekmektedir