Usage of hazelnut husk as growing media in Scarlet sage (Salvia splendens)

Bu çalışmada, Ateş çiçeğinin büyüme ve kalite parametreleri, fotosentetik pigmentleri ile besin maddesi içerikleri üzerine fındık zurufunun etkilerinin belirlenmesi amaçlanmıştır. Bu amaçla, Ateş çiçeği fideleri kontrol (%100 torf) ve farklı oranlarda fındık zurufu içeren altı yetiştirme ortamında beş yinelemeli olarak denenmiştir. Bitkilerde estetik görünümü, taç genişliği, çiçek sayısı ve ağırlığı, ana sürgün sayısı, bitki boyu, bitki yaş ve kuru ağırlıkları, kök yaş ve kuru ağırlıkları, klorofik a ve b, klorofil a+b, karotenoid, klorofil a+b/karotenoid ve besin içerikleri (N, P, K, Ca, Mg, Fe, Cu, Zn ve Mn) tespit edilmiştir. Ateş çiçeğinin kalsiyum, magnezyum ve demir dışındaki tüm özellikleri üzerine fındık zurufunun etkili olduğu ortaya çıkmıştır. Çalışmadaki özelliklerin en yüksek ortalama değerleri “%50 Torf/Perlit+%50 Fındık Zurufu” ortamından elde edilmiş olduğu için, ateş çiçeği için bu yetiştirme ortamı kullanılabilir. Ayrıca, deneme boyunca bitkilerde herhangi bir bitki besin maddesi noksanlığı gözlenmemiştir ancak bütün ortamlarda mangan değerinin düşük olması nedeni ile gübreleme programında mangan önerilebilir.In this study, it was aimed to determine the effects of hazelnut husk on the growth and quality parameters, photosynthetic pigments and nutrient content of Scarlet sage. For this purpose, the seedlings of Scarlet sage were tested in five replications on control (100% peat) and six growing media containing different proportions of hazelnut husk. In plants, aesthetic appearance, crown width, number and weight of flowers, number of main shoots, plant height, plant fresh and dry weights, root fresh and dry weights, chlorophyll a and b, chlorophyll a+b, carotenoid, chlorophyll a+b/carotenoid and nutrient contents (N, P, K, Ca, Mg, Fe, Cu, Zn and Mn) were determined. The study revealed that hazelnut husk was effective on all characteristics of Scarlet sage except calcium, magnesium and iron. Since the highest average values of the characteristics in the present study were obtained from growing media “50% Peat/Perlite+50% Hazelnut Husk”, this growing media can be used for Scarlet sage. In addition, no plant nutrient deficiencies were observed in the plants during the experiment, but manganese can be recommended in the fertilization program due to the its low value observed in all media

Sakarya akgöl organik toprağının domates bitkisinin kalite parametreleri üzerine etkisi

Tomato is the first ranking plant in greenhouse production both in Turkey and throughout the worldand various media are used for its cultivation. Peat is one of the most preferred media especially for its physical properties. In this study, the potential of Akgöl peat for use as a media for tomato cultivation was analyzed. For this purpose, five different media, including imported moss based peat and Akgöl peat were prepared and they were tested in tomato (Lycopersicon esculentum) cultivation in greenhouse conditions. Testing was conducted as five replicates according to Randomized Block Design. The result showed that there was no significant difference between quality parameters of the fruits except their Vitamin C contents. Total fruit yield and marketable fruit yield pof tomato grown in different media were found to be similar to each other. Tomato plants were successfully grown in all media. Therefore, it was concluded that Akgöl peat can be used as a medium in greenhouse as an alternative to imported moss based peatSerada gerçekleştirilen üretimde Dünya da ve ülkemizde birinci sırada yer alan bitki domatestir ve yetiştiriciliğinde çe-şitli ortamlar kullanılmaktadır. Organik topraklar daha çok fiziksel özellikleri nedeniyle en çok tercih edilen ortamlardan bi-ridir. Bu çalışmada, yerli Akgöl organik toprağının domates yetiştirme ortamı olarak kullanım olanakları belirlenmiştir. Bu sebeple ithal yosun kökenli organik toprak ve Akgöl organik toprağından oluşan beş farklı yetiştirme ortamı hazırlanmış ve sera koşullarında domates (Lycopersicon esculentum) bitkisinin yetiştirilmesiyle test edilmiştir. Deneme tesadüf blokları de-neme düzenine göre 5 paralelli olarak yürütülmüştür. Deneme sonucunda; domates bitkisinin meyvelerinde vitamin C dışın-daki diğer kalite parametrelerinde dikkate değer ayrımlar tespit edilmemiştir. Değişik ortamlarda yetiştirilen domates bitkile-rinin toplam meyve miktarı ve pazarlanabilir meyve ağırlıklarına ilişkin değerler birbirine yakın bulunmuştur. Domates bitki-leri ortamlarının tümünde başarılı bir şekilde yetiştirilmiştir. Bu nedenle yerli Akgöl organik toprağının seralarda yetiştirme ortamı olarak ithal yosun kökenli organik toprağa alternatif olarak kullanılabileceği sonucuna varılmıştır

Role of serum cathelicidin in diagnosis of patient with prostatitis and prostate carcinoma

Background: This study investigated the diagnostic role of 75 levels measured in serum prostatitis and prostate carcinoma and in the differentiation of these two conditions. Methods: The study was conducted with 75 patients histopathologically diagnosed with prostate carcinoma or prostatitis and followed up at the Departments of Urology and Medical Oncology and 21 healthy male subjects. Serum cathelicidin levels were investigated using the ELISA method. Statistical analyses were performed using the SPSS for Windows 22.0 package software. Compliance of the variables to normal distribution was examined using visual and analytic methods. In the Kolmogorov–Smirnov test, cases with a p value of greater than 0.05 were accepted as normal distribution. Results: A total of 75 patients including 45 diagnosed with prostate carcinoma and 30 diagnosed with prostatitis, as well as 21 healthy control subjects were included in the study. Prostate-specific antigen (PSA) was detected as 23 (4–1200) ng/mL in the patients with prostate carcinoma and as 9.85 (3.9–405 ng/mL) in the patients with prostatitis. The cathelicidin levels were diagnostically significant when assessed by ROC analysis in the prostate cancer, prostatitis and control groups (p = 0.005). The cutoff values derived from the ROC curve analysis were 3.5151 ng/mL for distinguishing prostate cancer from prostatitis, 2.2620 ng/mL for prostate cancer versus control group and 1.2340 ng/mL for prostatitis versus control group. Conclusions: In this study we showed that the serum cathelicidin levels were significantly higher in the patients diagnosed with prostate carcinoma. Measurement of serum cathelicidin levels could be used as a diagnostic marker in prostate carcinoma as well as facilitating differential diagnosis to strengthen the diagnostic suspicion before prostate biopsy and distinguish the diagnosis from prostatitis cases. © 2022, The Author(s)

Comparative physiological and growth responses of tomato and pepper plants to fertilizer induced salinity and salt stress under greenhouse conditions

Fertilizer induced salinity adversely affects plant growth through its ionic and osmotic effects as in ordinary salinity caused by toxic ions (Na, Cl, etc.). In this study, to determine the ionic and osmotic effects of fertilizer induced salinity and NaCl salinity on growth, ascorbic acid, proline and hydrogen peroxide (H2O2) accumulation and stomatal resistance (SR), relative water content (RWC), malondialdehyde (MDA) contents of tomato and pepper plants subjected to different treatments (i.e. control, 40 mM NaCl salinity and excess fertilizer salinity) were investigated under greenhouse condition. The results of this study indicated that similar to NaCl salinity, fertilizer induced salinity significantly reduced the fresh and dry weights of tomato and pepper plants. Relative water content of the plants was decreased by NaCl salinity. Both NaCl and fertilizer induced salinity caused significant increases in proline, MDA, ascorbic acid and H2O2 accumulation, and stomatal resistance of the plants. Salinity achieved by NaCl and fertilizer altered plant growth and plant physiological processes ionically and osmotically in a similar manner

Otizm Spektrum Bozukluğu Olan Çocukların Anne-Babalarında Psikolojik Dayanıklılık ve Kardeşlerinde Duygu Düzenleme Becerilerinin İncelenmesi

MUSTAFAOĞLU ÇİÇEK, Nuray. Investigation of Psychological Resilience in Parents of Children with Autism Spectrum Disorder and Emotion Regulation Skills in Siblings, PhD Dissertation, Ankara, 2019. The purpose of the present study was to investigate the experiences of parents of children with ASD in Turkey within the concept of resilience and to find out the factors that affect the level of resilience of parents. Moreover, emotion regulation abilities and experiences of healthy siblings of children with ASD aimed to be examined. For this purpose, a quantitative study was conducted to examine parents’ psychological resiliency and related factors in a total sample of 398 mothers and fathers; and a qualitative study was conducted to examine the experiences of nine mother-father dyads who were selected from parents with high psychological resilience. In the quantitative study, the association among socio-economic levels, emotional state (stress, anxiety, depression levels), cognitive emotion regulation strategies and psychological resilience of the mothers (N=251) and fathers (N=147) of children diagnosed with ASD were examined via correlational and hierarchical multiple regression analyses. The results pointed out that parents experienced less depression, anxiety and stress as their psychological resilience increased. Also, parents who had high resiliency were more likely tend to use the cognitive emotion regulation strategies such as positive reappraisal and positive refocusing. Furthermore, the findings indicated that the psychological resilience level decreased as the tendency to catastrophizing and blaming towards others increased. In addition, there was a positive relationship between psychological resilience of the parents and their education levels, and family income. In this study, the relationship between children’s ASD related behavioral problems and psychological resilience of parents showed a significant negative relationship. The relationship between the psychological resilience of mother-father dyads (N=139), their cognitive emotion regulation skills and their emotional states was examined by the Actor-Partner Interdepended Model (APIM). The findings of the analysis showed that maternal acceptance of the diagnosis was not related to the emotional state of fathers, but that paternal acceptance of the diagnosis reduced the impact of depression on mothers. Furthermore, based on the mothers’ reports, the association between behavioral, and social problems and emotion regulation skills of healthy siblings (N=108) and the relationship among emotion regulation levels of siblings with maternal psychological resilience, cognitive emotion regulation and emotional states were examined via hierarchical multiple regression analyses. As predicted, the emotion regulation skills of the siblings were negatively correlated with their behavioral and social problems. Emotion regulation of children was predicted by the tendency of mothers’ using positive refocusing strategy in a positive direction, and putting into perspective in a negative direction. There was a significant correlation between anxiety levels of mothers and emotion regulation skills of healthy siblings. In the qualitative study, semi-structured interviews were conducted with the parents with high psychological resilience (N=9 couples) in order to understand the dynamics that facilitated psychological resilience. The contents of the interviews were analyzed by interpretive phenomenological analysis method. The main themes, which are related to being parents of children diagnosed with ASD, the sources of resiliency in this process and parental experiences with healthy child, were comprised as a result of the qualitative study. The findings of the regression analyses and the themes based on the findings of qualitative study were discussed in the light of the related literature. In addition, the findings of quantitative and qualitative studies were comparatively interpreted, and recommendations for future research and practice were provided. Keywords Parents of children with ASD, healthy siblings of children with ASD, psychological resilience, emotional state, emotion regulation skills, interpretive phenomenological analysis.MUSTAFAOĞLU ÇİÇEK, Nuray. Otizm Spektrum Bozukluğu Olan Çocukların AnneBabalarında Psikolojik Dayanıklılık ve Kardeşlerinde Duygu Düzenleme Becerilerinin İncelenmesi, Doktora Tezi, Ankara, 2019. Bu araştırmanın amacı, Türkiye’deki çocuğu OSB tanılanmış ebeveynlerin deneyimlerini psikolojik dayanıklılık kavramı çerçevesinde ve sağlıklı gelişim gösteren kardeşlerin deneyimlerini duygu düzenleme becerileri çerçevesinde incelemektir. Bu amaç doğrultusunda, toplamda 398 anne ve babanın verilerine dayanan nicel çalışma ve psikolojik dayanıklılığı yüksek bulunan ebeveynlerden seçilen 9 anne-baba çiftinin deneyimlerini derinlemesine inceleyen nitel çalışma yürütülmüştür. Nicel çalışmada, OSB tanılanmış çocukların anne (N=251) ve babalarının (N=147) psikolojik dayanıklılıkları ile duygu durumu (stres, kaygı, depresyon düzeyleri), bilişsel duygu düzenleme yöntemleri ve sosyo-ekonomik düzeyleriyle ilişkisi korelasyon ve hiyerarşik çoklu regresyon analizleriyle incelenmiştir. Bulgular, anne ve babaların psikolojik dayanıklılığı arttıkça daha az depresyon, kaygı ve stres deneyimlediklerini göstermektedir. Ebeveynlerin kullandığı bilişsel duygu düzenleme yöntemlerinden durumu yeniden planlama ve olumlu gözden geçirme eğilimleri artıkça psikolojik dayanıklılıklarının da arttığı; durumu felaketleştirme (yıkım) ve diğerlerini suçlama eğilimleri arttıkça psikolojik dayanıklılık düzeyinin azaldığı görülmüştür. Ayrıca, anne-babaların eğitim düzeyleri ve aile gelir düzeyleri artıkça psikolojik dayanaklıklarının da arttığı bulunmuştur. Ek olarak mevcut çalışmada, çocukların OSB’yle ilişkili davranış sorunları ile ebeveynlerin psikolojik dayanıklılık düzeyi arasındaki ilişki incelenmiş ve çocukların davranış sorunları arttıkça ebeveynlerin psikolojik dayanıklılıklarının azaldığı bulunmuştur. Çalışmaya anne-baba çifti olarak katılan katılımcıların (N=139) psikolojik dayanıklılıklarının, bilişsel duygu düzenleme becerilerinin ve duygu durumlarının ilişkisi Aktör-Partner Karşılıklı Bağımlı Modelle (The Actor-Partner Interdepence Model, APIM) incelenmiştir. Analiz bulguları, annelerin durumu kabul etmelerinin babaların depresif durumlarıyla ilişkisi olmadığını, ancak babaların durumu kabul etmesinin annelerin depresif duygulanımlarını azalttığını göstermiştir. Ayrıca, anne bildirimlerine dayalı olarak, OSB tanılı çocukların sağlıklı gelişim gösteren kardeşlerinin (N=108) duygu düzenleme becerilerinin davranış sorunları ve sosyal etkileşimleriyle ve annelerin psikolojik dayanıklılık, bilişsel duygu düzenleme ve duygu durum düzeyleriyle etkileşimi hiyerarşik çoklu regresyon analizleriyle incelenmiştir. Çalışmanın hipotezlerinde öngörüldüğü gibi OSB tanılanmış çocuğun kardeşinin duygu düzenleme becerilerinin, çocuğun sosyal uyumu ile aynı doğrultuda, duygusal ve davranışsal problemleriyle ters yönde ilişkili olduğu bulunmuştur. Çocukların duygu düzenlemesini, annelerin durumu olumlu tekrar gözden geçirme stratejisini kullanma eğiliminin olumlu yönde, bakış açısına yerleştirme eğiliminin ters yönde yordadığı bulunmuştur. Annelerin kaygı düzeyleri ile çocukların duygu düzenleme becerileri arasında ters yönde anlamlı ilişki olduğu görülmüştür. Araştırmanın nitel çalışmasında, psikolojik dayanıklılıkları yüksek olan ailelerle (N=9 anne, 9 baba) psikolojik dayanıklılığı sağlayan etmenleri daha detaylı inceleyebilmek amacıyla yarı yapılandırılmış görüşmeler yapılmış ve bu görüşme içerikleri yorumlayıcı fenomenolojik analiz yöntemiyle analiz edilmiştir. Bunun sonucunda, OSB tanılanmış çocuğu olan ebeveyn olmak, bu süreçteki dayanıklılık kaynakları ve ebeveynlerin sağlıklı gelişim gösteren çocuklarıyla deneyimleri üzerine örneklemden çıkan temalar belirlenmiştir. Regresyon analizlerinden elde edilen bulgular ve nitel çalışma bulgularında ortaya çıkan temalar ilgili alanyazın ışığında tartışılmıştır. Ayrıca nicel ve nitel çalışmaların bulguları karşılaştırılarak yorumlanmış ve gelecek araştırmalara ve uygulamalara yönelik öneriler geliştirilmiştir. Anahtar Sözcükler Çocuğu OSB tanılanmış ebeveynler, OSB tanılanmış çocukların sağlıklı gelişim gösteren kardeşleri, psikolojik dayanıklılık, duygu durum, duygu düzenleme becerileri, yorumlayıcı fenomenolojik analiz

Ayçiçeği (Helianthus annuus L.) Bitkisinde Kadmiyum Toksisitesinin ÖnlenmesindePotasyumun Rolü

Tarım topraklarında ticari gübrelerin fazlaca kullanılması bitki organlarında ağır metal birikimi ile sonuçlanır ve bu da bitkide zehirlenme ile ürün ve kalite kaybına sebep olur. Bu çalışmada, kadmiyum (Cd) ve potasyumun (K) birlikte etkisine karşı ayçiçeği (Helianthus annuus L.) bitkisinin tepkisi araştırılmıştır. Bu amaçla, potasyumun üç (0200 ve 400 mg kg-1) ve kadmiyumun beş (0- 0,1- 0,3- 0,6 ve 1,2 mM) düzeyi toprağa uygulanmıştır. Sonuçlara göre artan Cd düzeyleri, ayçiçeği bitkisinde kök ve sürgünlerin kuru ağırlığı ve kök uzunluğu ile toplam klorofil (Chl) ve karotenoid (Car) içeriklerini azaltmış, ancak bu düzeyler yaprakların membran geçirgenliğini (MP) ve kadmiyumun toplam birikme oranını (TAR) artırmıştır. Potasyumun varlığında veya yokluğunda, sürgün ve kök Cd konsantrasyonu ve sürgün Cd alımı, Cd uygulamaları ile dikkate değer biçimde artmıştır. Ayrıca, uygulanan K dozları ile sürgün ve kökün her ikisinde de K alımını ve K konsantrasyonu önemli derecede artırmıştır.Using excessive commercial fertilizers in agricultural lands is resulted in accumulation of toxic heavy metals in soils and this causes toxicity in plant organs and losses of crop yield and quality in plants. In this study, response of sunflower (Helianthus annuus L.) plant to the mutual effects of cadmium (Cd) and potassium (K) were investigated. For this reason, five levels of Cd (0, 0.1, 0.3, 0.6, and 1.2 mM) and three levels of K (0, 200, and 400 mg kg-1) were applied to the soil. According to the results, increasing Cd levels decreased the shoot dry weight (DW), root DW, root length, total chlorophyll (Chl) and carotenoid (Car) contents, the shoot bio-concentration factor (BCF), and translocation factor (TF), whereas they increased the membrane permeability (MP) of the leaves and total accumulation rate (TAR) of Cd in sunflower. In the absence or presence of K, the shoot and root Cd concentration and shoot Cd uptake increased remarkably with Cd applications. Also, applied K levels increased significantly the K concentration and K uptake by both shoot and root

The Role of Children’s Emotion Regulation and Parental Emotion Socialization in Preschoolers’ Behavioral Difficulties during the COVID-19 Lockdown

Turkey, like many countries, implemented protective measures to combat the COVID-19 pandemic. One such measure involved isolating young children to reduce virus transmission. However, this regulation presented parents with the challenging task of juggling work responsibilities while caring for their young children without the usual support from external resources. Given these difficult circumstances, young children may struggle with emotion regulation, while isolation can impede parents from effectively addressing their children’s negative emotions. Therefore, this study aims to explore how children’s capacity for emotion regulation and maternal emotion socialization practices interact to predict children’s behavioral difficulties. The study revealed a positive correlation between maternal punitive and minimizing emotion socialization reactions and children’s behavioral difficulties. However, this association was primarily observed in children with high negative emotionality and low effortful control. Notably, when children had low negative emotionality scores, maternal minimizing emotion socialization behaviors were negatively associated with their behavior problems. These findings support the idea that during stressful periods, such as a pandemic, the diathesis-stress model may become more applicable. It emphasizes the interaction between individuals’ vulnerabilities (e.g., lower emotion regulation abilities) and environmental triggers (e.g., less supportive emotion socialization practices) leading to unfavorable outcomes, such as higher levels of children’s externalizing problems. These results underscore the importance of tailored intervention programs for parent-child dyads experiencing limited psychological resources during stressful events like a pandemic

Şanlıurfa ilinde doğurganlık çağındaki kadınlarda ELISA ile Toxoplasma gondii antikorlarının araştırılması: Üç yıllık değerlendirme

Amaç: Toxoplasma gondii’nin sebep olduğu Toksoplazmozis prevalansı coğrafik konuma, yaşa, beslenme ve hijyen alışkanlıklarına bağlı olarak prevalansı farklılıklar gösteren parazitik bir hastalıktır. Bu çalışmada, 01.01.2007-31.12.2009 tarihleri arasındaki üç yıllık dönemde Şanlıurfa Kadın Hastalıkları ve Doğum Hastanesi’ne başvuran risk grubunu oluşturan doğurganlık çağındaki kadınlarda konjenital enfeksiyonlara neden olabilen Toxoplasma gondii parazitine karşı oluşan antikorların seroprevalansının araştırılması ve daha önce yapılmış olan çalışmalarla karşılaştırılması amaçlanmıştır. Gereç ve yöntem: Yaşları 15-49 yıl arasında, yaş ortalaması 28.35±7.48 yıl olan doğurganlık çağındaki kadınlardan alınan serum örneklerinden kemilüminesans immüno assay ve ElectroChemiLuminescence yöntemi ile çalışılan toksoplazma antikor sonuçları retrospektif olarak değerlendirildi. Bulgular: Çalışılan serum örneklerinde gebe ve gebe olmayanlarda anti-Toksoplazma Ig G antikorlarının seropozitiflik yüzdesi sırasıyla %68.9 ve %63.0 olarak saptandı. Yine gebe ve gebe olmayan kadınlarda anti-Toksoplazma IgM seropozitiflik yüzdesi ise sırasıyla %2.8 ve %3.0 olarak bulundu. Anti-Toksoplazma IgG pozitifliği hem gebe hem gebe olmayan kadınlarda en çok 35-44 yaş grubunda görülmüş olup, bu durum istatistiksel olarak anlamlı bulundu (p<0.05). Sonuç: Bölgemizdeki gebe ve gebe olmayan kadınlarda yüksek oranda toksoplazma seropozitifliği saptadığımız için tarama gerekli olmayabilir kanısına varılmıştır. Duyarlı anne adaylarının toksoplazma infeksiyonlarından korunma ve kontrol konusunda eğitilmeleri ve takiplerinin doğumsal anomali riskini azaltacağı düşünülmüştür

Effects of different growth media to the nutrient content of primula (primula obconica) plant

Imported moss peat (IMP) and native peat (NAP) that is taken from Akgöl/Turkey were used in the growth medium of primula (Primula obconica) plants. Five different growth media were prepared using IMP and NAP, and some of their basic chemical and physical properties were determined. Then, the effects of media characteristics on nutrient contents of primula plant were evaluated. All growth media was found inadequate in concentration for water soluble nutrients NO3-N, P, K, Fe and Zn but other nutrients were acceptable levels. Bulk density (BD) of growing media was found between 0.071-0.139 g cm-3. When the ratio of NAP was increased in mixtures, BD also increased. Moreover, the growth media was prepared with IMP and NAP had enough aeration capacity (AC), low available water content (AWC), and very low water buffering capacity (WBC). Cation exchange capacity (CEC) values were determined as 83.32-105.70 me 100 g-1. pH and EC of the media varied between 4.56-5.88 and 0.39-1.00 dS m-1, respectively. On the other hand, when the NAP ratio was more than 75% in the mixtures, pH level was a little out of the desired limits. Organic C level was the highest in 100% IMP media. The quality parameters and the classical growth characteristics of primula plants were not significantly different across growing media. K, Mg, S and Na contents of the plants were generally at normal levels. However, significant differences were found in total Fe, Mn and Cu contents of plants. Fe amount was enough but Mn and Cu were lower than the acceptable levels in all media. All in all, primula plants were grown successfully in all media and reached saleable quality levels despite of the differences in some nutrient contents. It was suggested that NAP can be used as an alternative to IMP for horticultural purposes, such as a production of ornamentals in a greenhouse

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: A multicenter study

Introduction: Neuropsychiatric (NP) involvement is a restricted area in juvenile-onset systemic lupus erythematosus (jSLE). Aim: To investigate the prevalence, demographic and clinical features, and outcomes of the neurological involvement in the Turkish jSLE population. Methods: This study was based upon 24 referral centers’ SLE cohorts, multicenter and multidisciplinary network in Turkey. Patient data were collected by a case report form which was standardized for NP definitions according to American Collage of Rheumatology (ACR). Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) neuropsychiatric part was used to determine NP damage. Variables were evaluated Ward's hierarchical clustering analyses, univariate, and multivariate logistic regression analyses. Results: A hundred forty-nine of 1107 jSLE patients had NP involvement (13.5%). The most common NPSLE findings were headache (50.3%), seizure (38.3%), and acute confusional state (33.6%). Five clusters were identified with all clinical and laboratory findings. The first two clusters involved neuropathies, demyelinating diseases, aseptic meningitis, and movement disorder. Cluster 3 involved headache, activity markers and other SLE involvements. Idiopathic intracranial hypertension, cerebrovascular disease, cognitive dysfunction, psychiatric disorders and SLE antibodies were in the fourth, and acute confusional state was in the fifth cluster. In multivariate analysis, APA positivity; OR: 2.820, (%95CI: 1.002–7.939), P: 0,050, plasmapheresis; OR: 13.804 (%95CI: 2.785–68.432), P: 0,001, SLEDAI scores; OR: 1.115 (%95CI: (1.049–1.186), P: 0,001 were associated with increased risk for neurologic sequelae. Conclusion: We detected the prevalence of juvenile NPSLE manifestations in Turkey. We have identified five clusters that may shed light pathogenesis, treatment and prognosis of NP involvements. We also determined risk factors of neurological sequelae. Our study showed that new definitions NP involvements and sequelae for childhood period are needed