Herramienta para obtención de datos del sistema de publicidad online de LinkedIn

La publicidad online es un gran negocio sustentado en la compraventa de datos, donde empresas de redes sociales como Facebook o LinkedIn ofrecen anuncios personalizados en función de las características de sus usuarios. En este trabajo se diseña una herramienta software capaz de obtener información de manera automatizada y masiva de la plataforma de anuncios de LinkedIn que, dado un conjunto de características que definen a un público determinado dentro del conjunto de sus usuarios, informa del tamaño de este, el coste y rendimiento estimados de la campaña publicitaria y una segmentación adicional del público en función de una característica elegida, por ejemplo, los años de experiencia profesional. Toda esta información es relevante obtenida de forma masiva porque permite conocer el valor de cada conjunto de datos, obteniendo el coste de dirigirse a diferentes públicos específicos en tiempo real. El módulo implementado se integrará en una herramienta multiplataforma para cuantificar el valor de mercado de los datos. Además, estos datos permiten estudiar fenómenos sociales, en el caso de LinkedIn relacionados con el mercado laboral; por ello, para completar el trabajo se aborda un caso de uso de la herramienta implementada en el que se analiza la brecha de género por áreas laborales y países en todo el mundo. Los resultados demuestran la usabilidad de la herramienta para este tipo de estudios y revelan que los países menos desarrollados tienden a mostrar una mayor brecha de género, al menos dentro del conjunto de profesionales que utilizan LinkedIn.Ingeniería en Tecnologías de Telecomunicació

Estudio de factibilidad de una planta procesadora de productos derivados del fruto de coco para el Centro de Investigación, Experimentación y Transferencia de Tecnología Agroecológica en el municipio de San Pedro Masahuat, La Paz

El estudio presenta una propuesta de aprovechamiento integral del fruto de cocotero a través de la creación de una planta procesadora de productos derivados del fruto de cocotero, con el fin de generar sostenibilidad económica al Centro de Investigación, Experimentación y Transferencia de Tecnología Agroecológica (CIETTA). El estudio de factibilidad incluye una etapa de diagnóstico donde se realizó un estudio de mercado, una segunda etapa de diseño técnico donde se elaboraron subsistemas como: marketing, producción, calidad, etc. Y una tercera etapa de evaluaciones y administración del proyecto donde se presentan evaluaciones económicas, financieras, sociales, ambientales y de género. Con la realización de este trabajo se pretende mejorar la situación económica del CIETTA y de las cooperativas cocoteras afiliadas a CONFRAS, generando nuevas fuentes de empleo y otros beneficios en el municipio de San Pedro, Masahua

Fosfomycin versus meropenem in bacteraemic urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli (FOREST): study protocol for an investigator-driven randomised controlled trial

Introduction Finding therapeutic alternatives to carbapenems in infections caused by extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) is imperative. Although fosfomycin was discovered more than 40 years ago, it was not investigated in accordance with current standards and so is not used in clinical practice except in desperate situations. It is one of the so-called neglected antibiotics of high potential interest for the future. Methods and analysis The main objective of this project is to demonstrate the clinical non-inferiority of intravenous fosfomycin with regard to meropenem for treating bacteraemic urinary tract infections (UTI) caused by ESBL-EC. This is a ‘real practice’ multicentre, open-label, phase III randomised controlled trial, designed to compare the clinical and microbiological efficacy, and safety of intravenous fosfomycin (4 g/6 h) and meropenem (1 g/8 h) as targeted therapy for this infection; a change to oral therapy is permitted after 5 days in both arms, in accordance with predetermined options. The study design follows the latest recommendations for designing trials investigating new options for multidrug-resistant bacteria. Secondary objectives include the study of fosfomycin concentrations in plasma and the impact of both drugs on intestinal colonisation by multidrug-resistant Gram-negative bacilli. Ethics and dissemination Ethical approval was obtained from the Andalusian Coordinating Institutional Review Board (IRB) for Biomedical Research (Referral Ethics Committee), which obtained approval from the local ethics committees at all participating sites in Spain (22 sites). Data will be presented at international conferences and published in peer-reviewed journals. Discussion This project is proposed as an initial step in the investigation of an orphan antimicrobial of low cost with high potential as a therapeutic alternative in common infections such as UTI in selected patients. These results may have a major impact on the use of antibiotics and the development of new projects with this drug, whether as monotherapy or combination therapy

Bibliografía [Cuadernos del Instituto Antonio de Nebrija de estudios sobre la Universidad. 1999, nº 2]

Antonio Castillo. Escritura y escribientes (Enrique Villalba).-- Juan Carlos Domínguez Nafría. El jurisconsulto Benito Gutiérrez (M. Martínez Neira).-- Estado de la Universidad de Alcalá [1805], estudio preliminar de José Luis Peset (Pascual Marzal).-- Ramón González Navarro. Universidad y economía: el colegio mayor de San Ildefonso (A. Álvarez de Morales).-- Nathalie Gorochov. Le Collége de Navarre (Pascual Tamburri).-- J.L. Guereña y otros. L'Université en Espagne et en Amérique Latine, vol. I y II (Carolina Rodríguez).-- Luis Miguel Gutiérrez Torrecilla, Pedro Ballesteros Torres. Cátedras y catedráticos de la Universidad de Alcalá (Olga López).-- Luis Lorente. La real y pontificia Universidad de Toledo (M. Martínez Neira).-- M.G. Núñez Muñoz (coord.). Historia de la Universidad de la Laguna (Carolina Rodríguez).-- Laura Pasquino. Adolfo Levi. 1878-1948 (E. Hernández Sandoica).-- Antonio Pérez Martín. Españoles en el Alma Mater Studiorum (Pascual Tamburri).-- Juan Luis Polo Rodríguez. La universidad salmantina del antiguo régimen (J. Alejo Montes).-- Jaume Porta y Manuel Lladonosa (coords.). La universidad en el cambio de siglo (Carmen Merino).-- Renán Silva. Universidad y sociedad en el Nuevo Reino de Granada (Enrique Villalba).-- Sociedad Española de Historioa de la Educación (ed.). La universidad en el siglo XX (España e Iberoamérica) (CArmen Merino).-- Pascual Tamburri Bariain. Juristas y estudiantes españoles en Bolonia antes de la fundación del Colegio de España (M.A. Bermejo Castrillo).-- Luis Reis Torgal. A Universidade e o Estado Novo: 1926-1961 (E. Hernández Sandoica).-- C.Singer. Vichy, l'Université et les juifs. Id., L'Université libérée. L'Université épurée (Carolina Rodríguez).-- André Tuilier. Histoire de l'Université de Paris (A. Álvarez de Morales).-- Carlos Vattier Fuenzalida. Gumersindo de Azcárate (M. Martínez Neira).-- Olga Weijers. Le manieinent du savoir: XIII-XIV siècles. Id., La disputatio (A. Álvarez de Morales)Publicad

Mountain waves analysis in the vicinity of the Madrid-Barajas Airport using the WRF model

Turbulence and aircraft icing associated with mountain waves are weather phenomena potentially affecting aviation safety. In this paper, these weather phenomena are analysed in the vicinity of the Adolfo Su´arez Madrid-Barajas Airport (Spain). Mountain waves are formed in this area due to the proximity of the Guadarrama mountain range. Twenty different weather research and forecasting (WRF) model configurations are evaluated in an initial analysis. .is shows the incompetence of some experiments to capture the phenomenon. .e two experiments showing the best results are used to simulate thirteen episodes with observed mountain waves. Simulated pseudosatellite images are validated using satellite observations, and an analysis is performed through several skill scores applied to brightness temperature. Few differences are found among the different skill scores. Nevertheless, the .ompson microphysics scheme combined with the Yonsei university PBL scheme shows the best results. .e simulations produced by this scheme are used to evaluate the characteristic variables of the mountain wave episodes at windward and leeward and over the mountain. .e results show that north-northwest wind directions, moderate wind velocities, and neutral or slightly stable conditions are the main features for the episodes evaluated. In addition, a case study is analysed to evidence the WRF ability to properly detect turbulence and icing associated with mountain waves, even when there is no visual evidence available..is work was partially supported by the following research projects: PID2019-105306RB-I00, PCIN-2014-013-C07-04, and PCIN2016-080 (UE ERA-NET Plus NEWA Project), CGL2016-78702-C2-1-R and CGL2016-78702-C2-2-R (SAFEFLIGHT Project), FEI-EU-17-16 and SPESMARTand SPESVALE (ECMWF Special Projects)

Logros y retos en analítica del aprendizaje en España: La perspectiva de SNOLA

As in other research fields, the development of learning analytics is influenced by the networks of researchers that contribute to it. This paper describes one of such networks: the Spanish Network of Learning Analytics (SNOLA). The paper presents the research lines of the members of SNOLA, as well as the main challenges that learning analytics has to address in the next few years as perceived by these researchers. This analysis is based on SNOLA’s archival data and on a survey carried out to the current members of the network. Although this approach does not cover all the activity related to learning analytics in Spain, the results provide a representative overview of the current state of research related to learning analytics in this context. The paper describes these trends and the main challenges, among which we can point out the need to adopt an ethical commitment with data, to develop systems that respond to the requirements of the end users, and to reach a wider institutional impact.Tal y como ocurre en otros campos de investigación, el desarrollo de la analítica del aprendizaje está influido por las redes de investigadores que contribuyen al mismo. Este artículo describe una de estas redes: la Red Española de Analítica de Aprendizaje (SNOLA). El artículo presenta las líneas de investigación de los miembros de SNOLA, así como los principales retos que la analítica del aprendizaje tiene que afrontar en los próximos años desde la visión de estos investigadores. Este análisis está basado en datos de archivo de SNOLA y en una encuesta realizada a los actuales miembros de la red. Aunque esta aproximación no cubre toda la actividad relacionada con analítica del aprendizaje en España, los resultados proporcionan una visión general representativa del estado de la investigación relacionada con analítica del aprendizaje en dicho contexto. El artículo muestra cuáles son estas tendencias y los principales retos, entre los que se encuentran la necesidad de adoptar un compromiso ético con los datos, desarrollar sistemas que respondan a las necesidades de los usuarios y alcanzar mayor impacto institucional

Achievements and challenges in learning analytics in Spain: The view of SNOLA

[EN] As in other research fields, the development of learning analytics is influenced by the networks of researchers that contribute to it. This paper describes one of such networks: the Spanish Network of Learning Analytics (SNOLA). The paper presents the research lines of the members of SNOLA, as well as the main challenges that learning analytics has to address in the next few years as perceived by these researchers. This analysis is based on SNOLA’s archival data and on a survey carried out to the current members of the network. Although this approach does not cover all the activity related to learning analytics in Spain, the results provide a representative overview of the current state of research related to learning analytics in this context. The paper describes these trends and the main challenges, among which we can point out the need to adopt an ethical commitment with data, to develop systems that respond to the requirements of the end users, and to reach a wider institutional impact.[ES] Tal y como ocurre en otros campos de investigación, el desarrollo de la analítica del aprendizaje está influido por las redes de investigadores que contribuyen al mismo. Este artículo describe una de estas redes: la Red Española de Analítica de Aprendizaje (SNOLA). El artículo presenta las líneas de investigación de los miembros de SNOLA, así como los principales retos que la analítica del aprendizaje tiene que afrontar en los próximos años desde la visión de estos investigadores. Este análisis está basado en datos de archivo de SNOLA y en una encuesta realizada a los actuales miembros de la red. Aunque esta aproximación no cubre toda la actividad relacionada con analítica del aprendizaje en España, los resultados proporcionan una visión general representativa del estado de la investigación relacionada con analítica del aprendizaje en dicho contexto. El artículo muestra cuáles son estas tendencias y los principales retos, entre los que se encuentran la necesidad de adoptar un compromiso ético con los datos, desarrollar sistemas que respondan a las necesidades de los usuarios y alcanzar mayor impacto institucional.SIMinisterio de Ciencia, Innovación y Universidades ( RED2018-102725-T)Ministerio de Ciencia, Innovación y Universidades (TIN2016-80172-R)Junta de Castilla y León (VA257P18)Gobierno Vasco (IT980-16)Generalitat de Catalunya (2017SGR1619)Gobierno de la Comunidad de Madrid (S2018/TCS-4307

Calendario de vacunaciones de la Asociación Española de Pediatría: recomendaciones 2021

The CAV-AEP annually publishes the immunisation schedule considered optimal for all children and adolescent resident in Spain, taking into account the available evidence. The 2+1 schedule is recommended (2, 4, and 11 months) with hexavalent vaccines (DTPa-VPI-Hib-HB) and with 13-valent pneumococcal conjugate.A 6-year booster is recommended, preferably with DTPa (if available), with a dose of polio for those who received 2+1 schemes, as well as vaccination with Tdpa in adolescents and in each pregnancy, preferably between 27 and 32 weeks. Rotavirus vaccine should be systematic for all infants. Meningococcal B vaccine, with a 2+1 schedule, should be included in routine calendar. In addition to the inclusion of the conjugated tetravalent meningococcal vaccine (MenACWY) at 12 years of age with catch up to 18 years, inclusive, the CAV recommends this vaccine to be also included at 12 months of age, replacing MenC. Likewise, it is recommended in those over 6 weeks of age with risk factors or who travel to countries with a high incidence of these serogroups. Two-dose schedules for triple viral (12 months and 3-4 years) and varicella (15 months and 3-4 years) will be used. The second dose could be applied as a tetraviral vaccine. Universal systematic vaccination against HPV is recommended, regardless of gender, preferably at 12 years, and greater effort should be made to improve coverage. The 9 genotype extends coverage for both genders

Characteristics of patients with type 2 diabetes mellitus newly treated with GLP-1 receptor agonists (CHADIG Study): a cross-sectional multicentre study in Spain

Objective: Several glucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1Ra) have been made recently available in Spain for type 2 diabetes mellitus (DM2) treatment. There are no published data on the clinical and sociodemographic profile of patients initiating treatment with GLP-1Ra in Spain. Our objective was to understand these patients' characteristics in a real-world clinical practice setting. Design: Cross-sectional observational study. Setting: Spanish specialist outpatient clinics. Participants: 403 adults with DM2 initiating GLP-1Ra treatment were included. Primary and secondary outcome measures: Sociodemographic and DM2-related clinical data, including treatment at and after GLP-1Ra initiation and comorbidities, were collected. Results: Evaluable patients (n=403; 50.9% female) were included ( July 2013 to March 2014) at 24 centres by 53 specialists (47 endocrinology, 6 internal medicine), with the following profile (value±SD): age (58.3±10.4 years), diabetes duration (9.9±7 years), body mass index (BMI; 36.2±5.5) and glycated haemoglobin (HbA1c; 8.4±1.4%); 14% had HbA1c≤7%. Previous antidiabetic treatment: 53.8% only oral antidiabetic drugs (OADs), 5.2% insulin and 40% insulin and OAD; of those receiving OAD, 35% single drug, 38.2% 2 drugs and 24% 3 drugs. Concomitant to GLP-1Ra, 55.3% were only on OAD, 36.2% on insulin and OAD, and 7.2% only on insulin. Of those receiving OAD, the GLP-1Ra was mainly associated with 1 drug (65%) or 2 drugs (31.8%). GLP-1Ra are frequently added to existing antidiabetic drugs, with dipeptidyl peptidase-4 inhibitors being the OAD most frequently switched (45% receiving 1 before starting GLP-1Ra, only 2.7% receiving it concomitantly). Conclusions: In Spain, GLP-1Ra therapy is usually started in combination with OADs or OADs and insulin. These drugs are used in relatively young patients often not reaching therapeutic goals with other treatment combinations, roughly a decade after diagnosis and with a relatively high BMI. The latter could be explaine

CURRENT TRENDS IN RESEARCH METHODS FOR ENGINEERING: A CONTEMPORARY STUDY

This study is devoted to reviewing and analyzing current trends in engineering research methods, concentrating on modeling and simulation, machine learning, artificial intelligence, and complex systems engineering. Selected and analyzed academic articles published within the last five years were used to create a critical analysis. Despite the associated challenges, such as the need for new competencies and resources, the results indicated that these emergent methods significantly impact the engineering field. However, significant voids were also identified, including the inability to solve engineering problems innovatively and efficiently. This study concludes by emphasizing the need for additional in-depth research into these trends and their effects on various engineering disciplines