Magnetic Resonance Imaging of the Brain in Moving Subjects. Application of Fetal, Neonatal and Adult Brain Studies

Imaging in the presence of subject motion has been an ongoing challenge for magnetic resonance imaging (MRI). Motion makes MRI data inconsistent, causing artifacts in conventional anatomical imaging as well as invalidating diffusion tensor imaging (DTI) reconstruction. In this thesis some of the important issues regarding the acquisition and reconstruction of anatomical and DTI imaging of moving subjects are addressed; methods to achieve high resolution and high signalto- noise ratio (SNR) volume data are proposed. An approach has been developed that uses multiple overlapped dynamic single shot slice by slice imaging combined with retrospective alignment and data fusion to produce self consistent 3D volume images under subject motion. We term this method as snapshot MRI with volume reconstruction or SVR. The SVR method has been performed successfully for brain studies on subjects that cannot stay still, and in some cases were moving substantially during scanning. For example, awake neonates, deliberately moved adults and, especially, on fetuses, for which no conventional high resolution 3D method is currently available. Fine structure of the in-utero fetal brain is clearly revealed for the first time with substantially improved SNR. The SVR method has been extended to correct motion artifacts from conventional multi-slice sequences when the subject drifts in position during data acquisition. Besides anatomical imaging, the SVR method has also been further extended to DTI reconstruction when there is subject motion. This has been validated successfully from an adult who was deliberately moving and then applied to inutero fetal brain imaging, which no conventional high resolution 3D method is currently available. Excellent fetal brain 3D apparent diffusion coefficient (ADC) maps in high resolution have been achieved for the first time as well as promising fractional Anisotropy (FA) maps. Pilot clinical studies using SVR reconstructed data to study fetal brain development in-utero have been performed. Growth curves for the normally developing fetal brain have been devised by the quantification of cerebral and cerebellar volumes as well as some one dimensional measurements. A Verhulst model is proposed to describe these growth curves, and this approach has achieved a correlation over 0.99 between the fitted model and actual data

Global Nonlinear Kernel Prediction for Large Dataset with a Particle Swarm Optimized Interval Support Vector Regression

A new global nonlinear predictor with a particle swarm-optimized interval support vector regression (PSO-ISVR) is proposed to address three issues (viz., kernel selection, model optimization, kernel method speed) encountered when applying SVR in the presence of large data sets. The novel prediction model can reduce the SVR computing overhead by dividing input space and adaptively selecting the optimized kernel functions to obtain optimal SVR parameter by PSO. To quantify the quality of the predictor, its generalization performance and execution speed are investigated based on statistical learning theory. In addition, experiments using synthetic data as well as the stock volume weighted average price are reported to demonstrate the effectiveness of the developed models. The experimental results show that the proposed PSO-ISVR predictor can improve the computational efficiency and the overall prediction accuracy compared with the results produced by the SVR and other regression methods. The proposed PSO-ISVR provides an important tool for nonlinear regression analysis of big data

Storage Capacity Estimation of Commercial Scale Injection and Storage of CO2 in the Jacksonburg-Stringtown Oil Field, West Virginia

Geological capture, utilization and storage (CCUS) of carbon dioxide (CO2) in depleted oil and gas reservoirs is one method to reduce greenhouse gas emissions with enhanced oil recovery (EOR) and extending the life of the field. Therefore CCUS coupled with EOR is considered to be an economic approach to demonstration of commercial-scale injection and storage of anthropogenic CO2. Several critical issues should be taken into account prior to injecting large volumes of CO2, such as storage capacity, project duration and long-term containment. Reservoir characterization and 3D geological modeling are the best way to estimate the theoretical CO 2 storage capacity in mature oil fields. The Jacksonburg-Stringtown field, located in northwestern West Virginia, has produced over 22 million barrels of oil (MMBO) since 1895. The sandstone of the Late Devonian Gordon Stray is the primary reservoir.;The Upper Devonian fluvial sandstone reservoirs in Jacksonburg-Stringtown oil field, which has produced over 22 million barrels of oil since 1895, are an ideal candidate for CO2 sequestration coupled with EOR. Supercritical depth (\u3e2500 ft.), minimum miscible pressure (941 psi), favorable API gravity (46.5°) and good water flood response are indicators that facilitate CO 2-EOR operations. Moreover, Jacksonburg-Stringtown oil field is adjacent to a large concentration of CO2 sources located along the Ohio River that could potentially supply enough CO2 for sequestration and EOR without constructing new pipeline facilities.;Permeability evaluation is a critical parameter to understand the subsurface fluid flow and reservoir management for primary and enhanced hydrocarbon recovery and efficient carbon storage. In this study, a rapid, robust and cost-effective artificial neural network (ANN) model is constructed to predict permeability using the model\u27s strong ability to recognize the possible interrelationships between input and output variables. Two commonly available conventional well logs, gamma ray and bulk density, and three logs derived variables, the slope of GR, the slope of bulk density and Vsh were selected as input parameters and permeability was selected as desired output parameter to train and test an artificial neural network. The results indicate that the ANN model can be applied effectively in permeability prediction.;Porosity is another fundamental property that characterizes the storage capability of fluid and gas bearing formations in a reservoir. In this study, a support vector machine (SVM) with mixed kernels function (MKF) is utilized to construct the relationship between limited conventional well log suites and sparse core data. The input parameters for SVM model consist of core porosity values and the same log suite as ANN\u27s input parameters, and porosity is the desired output. Compared with results from the SVM model with a single kernel function, mixed kernel function based SVM model provide more accurate porosity prediction values.;Base on the well log analysis, four reservoir subunits within a marine-dominated estuarine depositional system are defined: barrier sand, central bay shale, tidal channels and fluvial channel subunits. A 3-D geological model, which is used to estimate theoretical CO2 sequestration capacity, is constructed with the integration of core data, wireline log data and geological background knowledge. Depending on the proposed 3-D geological model, the best regions for coupled CCUS-EOR are located in southern portions of the field, and the estimated CO2 theoretical storage capacity for Jacksonburg-Stringtown oil field vary between 24 to 383 million metric tons. The estimation results of CO2 sequestration and EOR potential indicate that the Jacksonburg-Stringtown oilfield has significant potential for CO2 storage and value-added EOR

Modeling and simulating of reservoir operation using the artificial neural network, support vector regression, deep learning algorithm

Reservoirs and dams are vital human-built infrastructures that play essential roles in flood control, hydroelectric power generation, water supply, navigation, and other functions. The realization of those functions requires efficient reservoir operation, and the effective controls on the outflow from a reservoir or dam. Over the last decade, artificial intelligence (AI) techniques have become increasingly popular in the field of streamflow forecasts, reservoir operation planning and scheduling approaches. In this study, three AI models, namely, the backpropagation (BP) neural network, support vector regression (SVR) technique, and long short-term memory (LSTM) model, are employed to simulate reservoir operation at monthly, daily, and hourly time scales, using approximately 30 years of historical reservoir operation records. This study aims to summarize the influence of the parameter settings on model performance and to explore the applicability of the LSTM model to reservoir operation simulation. The results show the following: (1) for the BP neural network and LSTM model, the effects of the number of maximum iterations on model performance should be prioritized; for the SVR model, the simulation performance is directly related to the selection of the kernel function, and sigmoid and RBF kernel functions should be prioritized; (2) the BP neural network and SVR are suitable for the model to learn the operation rules of a reservoir from a small amount of data; and (3) the LSTM model is able to effectively reduce the time consumption and memory storage required by other AI models, and demonstrate good capability in simulating low-flow conditions and the outflow curve for the peak operation period

Stacking-based uncertainty modelling of statistical and machine learning methods for residential property valuation

Estimating real estate prices helps to adapt informed policies to regulate the real estate market and assist sellers and buyers to have a fair business. This study aims to estimate the price of residential properties in District 5 of Tehran, Capital of Iran, and model its associated uncertainty. The study implements the Stacking technique to model uncertainties by integrating the outputs of basic models. Basic models must have a good performance for their combinations to have acceptable results. This study employs four statistical and machine learning models as basic models: Random Forest (RF), Ordinary Least Squares (OLS), Weighted K-Nearest Neighbour (WKNN), and Support Vector Regression (SVR) to estimate the price of residential properties. The results show that the integrated output is more accurate for the quadruple combination mode than for any of the binary and triple combinations of the basic models. Comparing the Stacking technique with the Voting technique, it is shown that the Mean Absolute Percentage Error (MAPE) reduces from 10.18% to 9.81%. Hence we conclude that our method performs better than the Voting technique.</p

Standardizing catch per unit effort by machine learning techniques in longline fisheries: a case study of bigeye tuna in the Atlantic Ocean

Support vector machine (SVM) is shown to have better performance in catch per unit of effort (CPUE) standardization than other methods. The SVM performance highly relates to its parameters selection and has not been discussed in CPUE standardization. Analyzing the influence of parameter selection on SVM performance for CPUE standardization could improve model construction and performance, and thus provide useful information to stock assessment and management. We applied SVM to standardize longline catch per unit fishing effort of fishery data for bigeye tuna (Thunnus obesus) in the tropical fishing area of Atlantic Ocean and evaluated three parameters optimization methods: a Grid Search method, and two improved hybrid algorithms, namely SVMs in combination with the particle swarm optimization (PSO-SVM), and genetic algorithms (GA-SVM), in order to increase the strength of SVM. The mean absolute error (MAE), mean square error (MSE), three types of correlation coefficients and the normalized mean square error (NMSE) were computed to compare the algorithm performances. The PSO-SVM and GA-SVM algorithms had particularly high performances of indicative values in the training data and dataset, and the performances of PSO-SVM were marginally better than GA-SVM. The Grid search algorithm had best performances of indicative values in testing data. In general, PSO was appropriate to optimize the SVM parameters in CPUE standardization. The standardized CPUE was unstable and low from 2007 to 2011, increased during 2011- 2013, then decreased from 2015 to 2017. The abundance index was lower compared with before 2000 and showed a decreasing trend in recent years

Kernel Methods for Surrogate Modeling

This chapter deals with kernel methods as a special class of techniques for surrogate modeling. Kernel methods have proven to be efficient in machine learning, pattern recognition and signal analysis due to their flexibility, excellent experimental performance and elegant functional analytic background. These data-based techniques provide so called kernel expansions, i.e., linear combinations of kernel functions which are generated from given input-output point samples that may be arbitrarily scattered. In particular, these techniques are meshless, do not require or depend on a grid, hence are less prone to the curse of dimensionality, even for high-dimensional problems. In contrast to projection-based model reduction, we do not necessarily assume a high-dimensional model, but a general function that models input-output behavior within some simulation context. This could be some micro-model in a multiscale-simulation, some submodel in a coupled system, some initialization function for solvers, coefficient function in PDEs, etc. First, kernel surrogates can be useful if the input-output function is expensive to evaluate, e.g. is a result of a finite element simulation. Here, acceleration can be obtained by sparse kernel expansions. Second, if a function is available only via measurements or a few function evaluation samples, kernel approximation techniques can provide function surrogates that allow global evaluation. We present some important kernel approximation techniques, which are kernel interpolation, greedy kernel approximation and support vector regression. Pseudo-code is provided for ease of reproducibility. In order to illustrate the main features, commonalities and differences, we compare these techniques on a real-world application. The experiments clearly indicate the enormous acceleration potentia

Learning to Find Eye Region Landmarks for Remote Gaze Estimation in Unconstrained Settings

Conventional feature-based and model-based gaze estimation methods have proven to perform well in settings with controlled illumination and specialized cameras. In unconstrained real-world settings, however, such methods are surpassed by recent appearance-based methods due to difficulties in modeling factors such as illumination changes and other visual artifacts. We present a novel learning-based method for eye region landmark localization that enables conventional methods to be competitive to latest appearance-based methods. Despite having been trained exclusively on synthetic data, our method exceeds the state of the art for iris localization and eye shape registration on real-world imagery. We then use the detected landmarks as input to iterative model-fitting and lightweight learning-based gaze estimation methods. Our approach outperforms existing model-fitting and appearance-based methods in the context of person-independent and personalized gaze estimation