Age and Huddling as Determinants of Metabolic Rate in Grasshopper Mice (Onychomys leucogaster)

The metabolic rates of grasshopper mice (Onychomys leucogaster) were determined every third day from birth to adulthood. Metabolic rates were quantitated by measuring oxygen consumption in an open circuit system. There was a rapid fall in oxygen consumption from the third day after birth until the ninth day. Mice which were housed separately assumed a constant metabolic rate at an earlier age than mice which were kept with litter-mates. The greatest increases in metabolism occurred when immature mice were separated from litter-mates for oxygen consumption determinations. It is concluded that huddling plays an important role in reducing the metabolic rate of young grasshopper mice

Bottom mixed layer oxygen dynamics in the Celtic Sea

The seasonally stratified continental shelf seas are highly productive, economically important environments which are under considerable pressure from human activity. Global dissolved oxygen concentrations have shown rapid reductions in response to anthropogenic forcing since at least the middle of the twentieth century. Oxygen consumption is at the same time linked to the cycling of atmospheric carbon, with oxygen being a proxy for carbon remineralisation and the release of CO2. In the seasonally stratified seas the bottom mixed layer (BML) is partially isolated from the atmosphere and is thus controlled by interplay between oxygen consumption processes, vertical and horizontal advection. Oxygen consumption rates can be both spatially and temporally dynamic, but these dynamics are often missed with incubation based techniques. Here we adopt a Bayesian approach to determining total BML oxygen consumption rates from a high resolution oxygen time-series. This incorporates both our knowledge and our uncertainty of the various processes which control the oxygen inventory. Total BML rates integrate both processes in the water column and at the sediment interface. These observations span the stratified period of the Celtic Sea and across both sandy and muddy sediment types. We show how horizontal advection, tidal forcing and vertical mixing together control the bottom mixed layer oxygen concentrations at various times over the stratified period. Our muddy-sand site shows cyclic spring-neap mediated changes in oxygen consumption driven by the frequent resuspension or ventilation of the seabed. We see evidence for prolonged periods of increased vertical mixing which provide the ventilation necessary to support the high rates of consumption observed

Metabolically exaggerated cardiac reactions to acute psychological stress revisited

The reactivity hypothesis postulates that large magnitude cardiovascular reactions to psychological stress contribute to the development of pathology. A key but little tested assumption is that such reactions are metabolically exaggerated. Cardiac activity, using Doppler echocardiography, and oxygen consumption, using mass spectrometry, were measured at rest and during and after a mental stress task and during graded submaximal cycling exercise. Cardiac activity and oxygen consumption showed the expected orderly association during exercise. However, during stress, large increases in cardiac activity were observed in the context of modest rises in energy expenditure; observed cardiac activity during stress substantially exceeded that predicted on the basis of contemporary levels of oxygen consumption. Thus, psychological stress can provoke increases in cardiac activity difficult to account for in terms of the metabolic demands of the stress tas

Investigations on the respiration of the Neotropical fish, Colossoma macropomum (Serrasalmidae). The influence of weight and temperature on the routine oxygen consumption

The influence of weight and temperature on the routine oxygen consumption of Colossoma macropomum, a Neotropical fish species of the family Serrasalmidae, was investigated using a constant flow respirometer. Plotted on a double logarithmic grid, oxygen consumption increases linearly with weight. Slopes of 0.64 at 25 and 30 °C, and 0.78 at 35 °C were obtained. Because of the significant difference in the slopes, a general value could not be provided. The metabolic rate of a 100 g fish increases from 103.7 to 191.5 and 289.7 mg O2/kg/h at 20, 25, and 30 °C, respectively. At 35 °C, the oxygen consumption rate decreased to 212.4 mg O2/kg/h. The metabolic rate is comparable to those of other tropical fish species. Obviously, Colossoma macropomum is well adapted to the constant temperature conditions of its Neotropical habitats

Method and system for respiration analysis Patent

Respiration analyzing method and apparatus for determining subjects oxygen consumption in aerospace environment

Effect of music-movement synchrony on exercise oxygen consumption

The published full-text article can be accessed at the link below.AIM: Past research indicates that endurance is improved when exercise movements are synchronised with a musical beat, however it is unclear whether such benefits are associated with reduced metabolic cost. We compared oxygen consumption (VO2) and related physiological effects of exercise conducted synchronously and asynchronously with music. METHODS: Three music tracks, each recorded at three different tempi (123, 130, and 137 beats.min-1), accompanied cycle ergometry at 65 pedal revolutions.min-1. Thus three randomly-assigned experimental conditions were administered: slow tempo asynchronous, synchronous, and fast tempo asynchronous. Exercise response of VO2, HR, and ratings of perceived exertion (RPE), to each condition was monitored in 10 untrained male participants aged 21.7±0.8 years (mean±SD) who cycled for 12 min at 70% maximal heart rate (HR). RESULTS: Mean VO2 differed among conditions (P=0.008), being lower in the synchronous (1.80±0.22 L.min-1) compared to the slow tempo asynchronous condition (1.94±0.21 L.min-1; P<0.05). There was no difference in HR or RPE among conditions, although HR showed a similar trend to VO2. CONCLUSION: The present results indicate that exercise is more efficient when performed synchronously with music than when musical tempo is slightly slower than the rate of cyclical movement

Plant respirometer enables high resolution of oxygen consumption rates

Plant respirometer permits high resolution of relatively small changes in the rate of oxygen consumed by plant organisms undergoing oxidative metabolism in a nonphotosynthetic state. The two stage supply and monitoring system operates by a differential pressure transducer and provides a calibrated output by digital or analog signals

PO2 dependence of oxygen consumption in skeletal muscle of hypertensive and normotensive rats

Human essential hypertension affects over 75 million people in the United States, and can lead to death due to its several serious health complications such as hypertension-related cardiovascular disease. The purpose of this research was to understand how hypertension could cause physiological changes to the microcirculation, specifically the PO2 dependence of oxygen consumption (VO2) in skeletal muscle of normotensive and hypertensive rats. The Spontaneously Hypertensive Rat (SHR) strain was used as the diseased model, and Wistar-Kyoto (WKY) rats were used as controls to conduct this study. The SHR strain develops hypertension between 5-6 weeks after birth with an average systolic blood pressure of 150 mmHg. By arresting blood flow using an objective-mounted inflatable airbag, PO2 measurements were obtained along with an oxygen disappearance curve (ODC), which was used to calculate VO2 over various ranges of physiological PO2 values. PO2 and VO2 curves were analyzed based on Hill’s equation to fit the data and describe the PO2 dependence of VO2. When compared to the healthy Wistar-Kyoto rats, the SHRs exhibited a higher Vmax, or maximum rate of oxygen consumption. The average maximal rate of consumption by the hypertensive animal models could be a consequence of a “mitochondrial uncoupling” or some disconnect in the mitochondrial oxygen consumption and the normal corresponding ATP production. In conclusion, this project demonstrated that in situ muscle tissue from hypertensive and normotensive rats had a PO2 dependence of oxygen consumption over a wide range of physiological PO2 values and the hypertensive rats consumed oxygen at a higher maximal rate

Increased Metabolic Rate in X-linked Hypophosphatemic Mice

Hyp mice are a model for human X-linked hypophosphatemia, the most common form of vitamin D-resistant rickets. It has previously been observed that Hyp mice have a greater food consumption per gram body weight than do normal mice. This led to the search for some alteration in metabolism in Hyp mice. We found that oxygen consumption was significantly higher in Hyp mice than in normal C57BL/6J mice and this was accompanied by an increased percentage of cardiac output being delivered to organs of heat production (liver and skeletal muscle), to the skin, and to bone and a decreased percentage to the gastrointestinal tract of Hyp mice. The increased oxygen consumption in Hyp mice was not associated with increased plasma free T4 levels and was not affected by alterations in plasma phosphate produced by a low phosphate diet. The cause of the increased oxygen consumption is not known, and the role that this change and reported changes in distribution of cardiac output may play in the development of X-linked hypophosphatemia is also unknown. Study of the cardiovascular and thermoregulatory systems in Hyp mice should help increase understanding of the underlying mechanisms of this disease

State of gas exchange in recumbent and orthostatic positions and under physical load in healthy persons of varying age, sex and body build

Age effect on gas exchange was studied in the recumbent and orthostatic positions and under physical load. In the case of the older age group and for normal as compared with hypersthenic persons, oxygen consumption during rest and during moderate physical overload diminishes. When the vertical position is assumed oxygen consumption in persons of various age groups is distinctly increased, particularly in the elderly group. There is a reduction in the amount of oxygen consumption, oxygen pulse, recovery coefficient, and work efficiency under moderate overload. In persons over 50, physical labor induces a large oxygen requirement and a sharp rise in the level of lactic acid and the blood's lactate/pyruvate ratio. No distinct difference was noted in the amount of oxygen consumed during rest and during physical overload in men and women of the same physical development and age