Engineering model transformations with transML

The final publication is available at Springer via http://dx.doi.org/10.1007%2Fs10270-011-0211-2Model transformation is one of the pillars of model-driven engineering (MDE). The increasing complexity of systems and modelling languages has dramatically raised the complexity and size of model transformations as well. Even though many transformation languages and tools have been proposed in the last few years, most of them are directed to the implementation phase of transformation development. In this way, even though transformations should be built using sound engineering principles—just like any other kind of software—there is currently a lack of cohesive support for the other phases of the transformation development, like requirements, analysis, design and testing. In this paper, we propose a unified family of languages to cover the life cycle of transformation development enabling the engineering of transformations. Moreover, following an MDE approach, we provide tools to partially automate the progressive refinement of models between the different phases and the generation of code for several transformation implementation languages.This work has been sponsored by the Spanish Ministry of Science and Innovation with project METEORIC (TIN2008-02081), and by the R&D program of the Community of Madrid with projects “e-Madrid" (S2009/TIC-1650). Parts of this work were done during the research stays of Esther and Juan at the University of York, with financial support from the Spanish Ministry of Science and Innovation (grant refs. JC2009-00015, PR2009-0019 and PR2008-0185)

Big Data in Laboratory Medicine—FAIR Quality for AI?

Laboratory medicine is a digital science. Every large hospital produces a wealth of data each day—from simple numerical results from, e.g., sodium measurements to highly complex output of “-omics” analyses, as well as quality control results and metadata. Processing, connecting, storing, and ordering extensive parts of these individual data requires Big Data techniques. Whereas novel technologies such as artificial intelligence and machine learning have exciting application for the augmentation of laboratory medicine, the Big Data concept remains fundamental for any sophisticated data analysis in large databases. To make laboratory medicine data optimally usable for clinical and research purposes, they need to be FAIR: findable, accessible, interoperable, and reusable. This can be achieved, for example, by automated recording, connection of devices, efficient ETL (Extract, Transform, Load) processes, careful data governance, and modern data security solutions. Enriched with clinical data, laboratory medicine data allow a gain in pathophysiological insights, can improve patient care, or can be used to develop reference intervals for diagnostic purposes. Nevertheless, Big Data in laboratory medicine do not come without challenges: the growing number of analyses and data derived from them is a demanding task to be taken care of. Laboratory medicine experts are and will be needed to drive this development, take an active role in the ongoing digitalization, and provide guidance for their clinical colleagues engaging with the laboratory data in research

Big Data Computing for Geospatial Applications

The convergence of big data and geospatial computing has brought forth challenges and opportunities to Geographic Information Science with regard to geospatial data management, processing, analysis, modeling, and visualization. This book highlights recent advancements in integrating new computing approaches, spatial methods, and data management strategies to tackle geospatial big data challenges and meanwhile demonstrates opportunities for using big data for geospatial applications. Crucial to the advancements highlighted in this book is the integration of computational thinking and spatial thinking and the transformation of abstract ideas and models to concrete data structures and algorithms

Ontology-based data integration between clinical and research systems

Data from the electronic medical record comprise numerous structured but uncoded elements, which are not linked to standard terminologies. Reuse of such data for secondary research purposes has gained in importance recently. However, the identification of relevant data elements and the creation of database jobs for extraction, transformation and loading (ETL) are challenging: With current methods such as data warehousing, it is not feasible to efficiently maintain and reuse semantically complex data extraction and trans-formation routines. We present an ontology-supported approach to overcome this challenge by making use of abstraction: Instead of defining ETL procedures at the database level, we use ontologies to organize and describe the medical concepts of both the source system and the target system. Instead of using unique, specifically developed SQL statements or ETL jobs, we define declarative transformation rules within ontologies and illustrate how these constructs can then be used to automatically generate SQL code to perform the desired ETL procedures. This demonstrates how a suitable level of abstraction may not only aid the interpretation of clinical data, but can also foster the reutilization of methods for un-locking it

Supporting the grow-and-prune model for evolving software product lines

207 p.Software Product Lines (SPLs) aim at supporting the development of a whole family of software products through a systematic reuse of shared assets. To this end, SPL development is separated into two interrelated processes: (1) domain engineering (DE), where the scope and variability of the system is defined and reusable core-assets are developed; and (2) application engineering (AE), where products are derived by selecting core assets and resolving variability. Evolution in SPLs is considered to be more challenging than in traditional systems, as both core-assets and products need to co-evolve. The so-called grow-and-prune model has proven great flexibility to incrementally evolve an SPL by letting the products grow, and later prune the product functionalities deemed useful by refactoring and merging them back to the reusable SPL core-asset base. This Thesis aims at supporting the grow-and-prune model as for initiating and enacting the pruning. Initiating the pruning requires SPL engineers to conduct customization analysis, i.e. analyzing how products have changed the core-assets. Customization analysis aims at identifying interesting product customizations to be ported to the core-asset base. However, existing tools do not fulfill engineers needs to conduct this practice. To address this issue, this Thesis elaborates on the SPL engineers' needs when conducting customization analysis, and proposes a data-warehouse approach to help SPL engineers on the analysis. Once the interesting customizations have been identified, the pruning needs to be enacted. This means that product code needs to be ported to the core-asset realm, while products are upgraded with newer functionalities and bug-fixes available in newer core-asset releases. Herein, synchronizing both parties through sync paths is required. However, the state of-the-art tools are not tailored to SPL sync paths, and this hinders synchronizing core-assets and products. To address this issue, this Thesis proposes to leverage existing Version Control Systems (i.e. git/Github) to provide sync operations as first-class construct

Whitepaper on Reusable Hybrid and Multi-Cloud Analytics Service Framework

Over the last several years, the computation landscape for conducting data analytics has completely changed. While in the past, a lot of the activities have been undertaken in isolation by companies, and research institutions, today's infrastructure constitutes a wealth of services offered by a variety of providers that offer opportunities for reuse, and interactions while leveraging service collaboration, and service cooperation. This document focuses on expanding analytics services to develop a framework for reusable hybrid multi-service data analytics. It includes (a) a short technology review that explicitly targets the intersection of hybrid multi-provider analytics services, (b) a small motivation based on use cases we looked at, (c) enhancing the concepts of services to showcase how hybrid, as well as multi-provider services can be integrated and reused via the proposed framework, (d) address analytics service composition, and (e) integrate container technologies to achieve state-of-the-art analytics service deploymen