Mild cognitive impairment (MCI) gangguan kognitif ringan

The aging process of the brain could not be avoided. The changes in brain function related to aging is decline in the memory function e.g. anomia and speed of information retrieval from memory. These changes were the results of declines in learning or acquisition as a failure of consolidation process or decline in the ability to transfer information from primary to secondary memory. Memory impairment, forgetful, affected elderly people. The common complaints are anomia, recall, and retrieval, but could benefitted from cues. Memory complaint is not related on objective memory evaluation. This impairment is primarily due to delayed recall. These complaints are influenced by depression, anxiety, and personality trait and failure in dealing with memory strategy. Mild Cognitive impairment (MC1) is a transitional state between forgetfulness and Alzheimer disease. People with MCI are of high risk to Alzheimer dementia with a rate of 10-12 percent annually. Specific criteria of MCI are decline in recent memory, decline in memory performance on memory test, normal general cognitive function and not demented. Key words : normal aging - forgetfulness - mild cognitive impairment - Alzheimer\u27 diseas

Orthostatic intolerance predicts mild cognitive impairment: incidence of mild cognitive impairment and dementia from the Swedish general population cohort Good Aging in Skåne.

Contradictory results have been reported on the relationship between orthostatic hypotension (OH) and mild cognitive impairment (MCI)

Interventions for Persons with Mild Cognitive Impairment (MCI) An Evidence-Based Practice Project

This Evidence-Based Practice (EBP) project addressed the following question: What occupational therapy and multidisciplinary/interprofessional interventions are most effective for addressing mild cognitive impairment (MCI) to improve occupational performance, functional cognition, participation, well-being, quality of life, and caregiver burden

Process for Detection of Alzheimer\u27s Disease from a Serum Sample

Disclosed is a method of detecting a concentration of a biomarker in a human subject having or being at risk of developing Alzheimer\u27s disease or Mild Cognitive Impairment (MCI). Also disclosed is a process for detecting a concentration of a biomarker in a human subject having or being at risk of developing Alzheimer\u27s disease or Mild Cognitive Impairment (MCI) comprising (a) detecting a first concentration of lipocalin-PDS/TTR complex in a blood sample or urine sample from the subject, (b) determining a second concentration of PDS/TTR complex in a blood sample or urine sample from an unaffected individual, and ( c) comparing the first and second concentrations, wherein a lower first concentration as compared to the second concentration is indicative of the subject having or being at risk of developing Alzheimer\u27s disease

Occurrence of medical co-morbidity in mild cognitive impairment: implications for generalisation of MCI research

Background: diagnosis of mild cognitive impairment (MCI) typically excludes individuals with medical co-morbidity. Interest in MCI screening raises the questions of what are the best criteria to identify a representative sample and what factors are associated with MCI progression to dementia

Asymmetric Cerebral Blood Flow in Patients with Mild Cognitive Impairment: Possible Relationship to Further Cognitive Deterioration

To explore patterns of cerebral blood flow in patients with mild cognitive impairment (MCI), who (1) eventually deteriorate into overt dementia, with no particular focus on the type of dementia, or (2) do not appear to further deteriorate in their cognitive functions

Cholinesterase Inhibitors in Mild Cognitive Impairment: A Systematic Review of Randomised Trials

A systematic review of trials of cholinesterase inhibitors for preventing transition of mild cognitive impairment (MCI) to dementia, conducted by Roberto Raschetti and colleagues, found no difference between treatment and control groups and concluded that uncertainty regarding the definition of MCI casts doubts on the validity of such trials

Investigation of ICA algorithms for feature extraction of EEG signals in discrimination of Alzheimer disease

In this paper we present a quantitative comparisons of different independent component analysis (ICA) algorithms in order to investigate their potential use in preprocessing (such as noise reduction and feature extraction) the electroencephalogram (EEG) data for early detection of Alzhemier disease (AD) or discrimination between AD (or mild cognitive impairment, MCI) and age-match control subjects

Neuropsychiatric, neuropsychological, and neuroimaging features in isolated REM sleep behavior disorder: The importance of MCI

Mild cognitive impairment (MCI) is frequently diagnosed in patients with isolated rapid eye movement (REM) sleep behavior disorder (iRBD), although the extent of MCI-associated neuropathology has not yet been quantified. The present study compared the differences in neuropsychiatric, neuropsychological, and neuroimaging markers of neurodegeneration in MCI-iRBD and iRBD patients with normal cognition