275,802 research outputs found

    The Role of Education in Determining Labor Market Outcomes in Urban China's Transitional Labor Markets.

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    Chinese urban workers are no longer shielded from market forces. They are bearing the brunt of the adjustment costs as enterprises shed redundant workers. This paper focuses on the role of education in determining labor market outcomes in China's rapidly changing urban labor environment. The empirical work, based on enterprise and worker survey data gathered in the fall of 1999 and spring of 2000, demonstrates that education is a key determinant of labor market outcomes. Educational attainment is an important and significant factor in the lay-off decision-the more education a worker has the better his/ her protection from lay off. Similarly, the more education a worker has the better his/her chances of finding new employment once laid off. The human capital accumulation of re-employed workers is rewarded more, as measured in terms of incremental earnings for each additional year of schooling, than that of continuously employed workers.http://deepblue.lib.umich.edu/bitstream/2027.42/39843/3/wp459.pd

    Evaluation of ASTER GDEM ver2 using GPS measurements and SRTM ver4.1 in China

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    The freely available ASTER GDEM ver2 was released by NASA and METI on October 17, 2011. As one of the most complete high resolution digital topographic data sets of the world to date, the ASTER GDEM covers land surfaces between 83°N and 83°S at a spatial resolution of 1 arc-second and will be a useful product for many applications, such as relief analysis, hydrological studies and radar interferometry. The stated improvements in the second version of ASTER GDEM benefit from finer horizontal resolution, offset adjustment and water body detection in addition to new observed ASTER scenes. This study investigates the absolute vertical accuracy of the ASTER GDEM ver2 at five study sites in China using ground control points (GCPs) from high accuracy GPS benchmarks, and also using a DEM-to-DEM comparison with the Consultative Group for International Agriculture Research Consortium for Spatial Information (CGIAR-CSI) SRTM DEM (Version 4.1). And then, the results are separated into GlobCover land cover classes to derive the spatial pattern of error. It is demonstrated that the RMSE (19m) and mean (-13m) values of ASTER GDEM ver2 against GPS-GCPs in the five study areas is lower than its first version ASTER GDEM ver1 (26m and -21m) as a result of the adjustment of the elevation offsets in the new version. It should be noted that the five study areas in this study are representative in terms of terrain types and land covers in China, and even for most of mid-latitude zones. It is believed that the ASTER GDEM offers a major alternative in accessibility to high quality elevation data

    Aerobic stability of heat and orchardgrass round-bale silage

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    In Arkansas, silage is typically stored as balage in long rows of round bales wrapped in plastic film. It is important to evaluate the aerobic stability of this fermented forage when it is exposed to air, especially during the winter months when most of it is fed to livestock or sold as a cash crop. Two types of forage, orchardgrass (Dactylis glomerata) and wheat (Triticum aestivum), were harvested in May 2002 and stored as balage. Twenty-one bales of each balage type were unwrapped and exposed to air on 10 Dec. 2002 for 0, 2, 4, 8, 16, 24, or 32 d to evaluate aerobic stability. For both orchardgrass and wheat balage, final bale weight, dry matter (DM) content, and pH were not affected (P \u3e 0.05) by exposure time. Across both balage types, DM recoveries were ≥97% for all bales, indicating that both types of balage were very stable when exposed to air. Concentrations of neutral detergent fiber (NDF) and 48-h ruminal in situ digestibility were not affected (P \u3e 0.05) by exposure time for either balage type. Concentrations of N were greater (P = 0.045) for orchardgrass balage exposed to air for 16 d or longer compared to balage sampled at exposure (d 0), but this response was not observed (P \u3e 0.05) for wheat balage. These results suggest that the balage evaluated in this trial was very stable after exposure to air for up to 32 d. This should allow for considerable flexibility with respect to feeding, transport, and marketing of balage during winter months without significant aerobic deterioration

    Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors.

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    The polo-like kinase 1 (Plk1) is a critical regulator of cell division that is overexpressed in many types of tumors. Thus, a strategy in the treatment of cancer has been to target the kinase activity (ATPase domain) or substrate-binding domain (Polo-box Domain, PBD) of Plk1. However, only few synthetic small molecules have been identified that target the Plk1-PBD. Here, we have applied an integrative approach that combines pharmacophore modeling, molecular docking, virtual screening, and in vitro testing to discover novel Plk1-PBD inhibitors. Nine Plk1-PBD crystal structures were used to generate structure-based hypotheses. A common pharmacophore model (Hypo1) composed of five chemical features was selected from the 9 structure-based hypotheses and used for virtual screening of a drug-like database consisting of 159,757 compounds to identify novel Plk1-PBD inhibitors. The virtual screening technique revealed 9,327 compounds with a maximum fit value of 3 or greater, which were selected and subjected to molecular docking analyses. This approach yielded 93 compounds that made good interactions with critical residues within the Plk1-PBD active site. The testing of these 93 compounds in vitro for their ability to inhibit the Plk1-PBD, showed that many of these compounds had Plk1-PBD inhibitory activity and that compound Chemistry_28272 was the most potent Plk1-PBD inhibitor. Thus Chemistry_28272 and the other top compounds are novel Plk1-PBD inhibitors and could be used for the development of cancer therapeutics

    The comparative study of nursing pads by electrospun cellulose acetate, polyethylene oxide and thermoplastic polyurethane nanofibers

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    This study summarizes the general information about nursing pads and novel electrospun nanofiber mats as potential component for nursing pads. It also compares electrospun thermoplastic polyurethane (TPU), cellulose acetate (CA) and polyethylene oxide (PEO) nanofibers with a polypropylene conventional disposable nursing pad (NP) in terms of hydrophilicity, breathability, air permeability and swelling properties. Nanofiber mats prepared by the electrospinning method have unique properties such as smooth surface, high specific surface area and high porosity with fine pores which will lead to improved wicking properties. These properties make nanofibers potential component for disposable nursing pads. Mean diameters of produced nanofibers were 284.39, 609.70 and 219.30 nm for CA, TPU and PEO, respectively. Water contact angle measurement revealed that these nanofibers show good wettability properties better than commercial nonwoven nursing mat and air permeability results revealed that these nanofibrous mats have considerably adequate permeability. Besides, water vapor permeability results showed these nanofibers still show good breathability despite their compact structure. © Published under licence by IOP Publishing Ltd

    Species-specific forest variable estimation using non-parametric modeling of multi-spectral photogrammetric point cloud data

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    The recent development in software for automatic photogrammetric processing of multispectral aerial imagery, and the growing nation-wide availability of Digital Elevation Model (DEM) data, are about to revolutionize data capture for forest management planning in Scandinavia. Using only already available aerial imagery and ALS-assessed DEM data, raster estimates of the forest variables mean tree height, basal area, total stem volume, and species-specific stem volumes were produced and evaluated. The study was conducted at a coniferous hemi-boreal test site in southern Sweden (lat. 58° N, long. 13° E). Digital aerial images from the Zeiss/Intergraph Digital Mapping Camera system were used to produce 3D point-cloud data with spectral information. Metrics were calculated for 696 field plots (10 m radius) from point-cloud data and used in k-MSN to estimate forest variables. For these stands, the tree height ranged from 1.4 to 33.0 m (18.1 m mean), stem volume from 0 to 829 m3 ha-1 (249 m3 ha-1 mean) and basal area from 0 to 62.2 m2 ha-1 (26.1 m2 ha-1 mean), with mean stand size of 2.8 ha. Estimates made using digital aerial images corresponding to the standard acquisition of the Swedish National Land Survey (Lantmäteriet) showed RMSEs (in percent of the surveyed stand mean) of 7.5% for tree height, 11.4% for basal area, 13.2% for total stem volume, 90.6% for pine stem volume, 26.4 for spruce stem volume, and 72.6% for deciduous stem volume. The results imply that photogrammetric matching of digital aerial images has significant potential for operational use in forestry

    Beyond Gibbs-Boltzmann-Shannon: General Entropies -- The Gibbs-Lorentzian Example

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    We propose a generalisation of Gibbs' statistical mechanics into the domain of non-negligible phase space correlations. Derived are the probability distribution and entropy as a generalised ensemble average, replacing Gibbs-Boltzmann-Shannon's entropy definition enabling construction of new forms of statistical mechanics. The general entropy may also be of importance in information theory and data analysis. Application to generalised Lorentzian phase space elements yields the Gibbs-Lorentzian power law probability distribution and statistical mechanics. Details can be found in arXiv:1406.6639Comment: 6 pages, no figures, paper appeared in slightly different form in. For details on application see arXiv:1406.663

    Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries

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    IMPORTANCE: Limited information exists about the epidemiology, recognition, management, and outcomes of patients with the acute respiratory distress syndrome (ARDS). OBJECTIVES: To evaluate intensive care unit (ICU) incidence and outcome of ARDS and to assess clinician recognition, ventilation management, and use of adjuncts-for example prone positioning-in routine clinical practice for patients fulfilling the ARDS Berlin Definition. DESIGN, SETTING, AND PARTICIPANTS:The Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) was an international, multicenter, prospective cohort study of patients undergoing invasive or noninvasive ventilation, conducted during 4 consecutive weeks in the winter of 2014 in a convenience sample of 459 ICUs from 50 countries across 5 continents. EXPOSURES:Acute respiratory distress syndrome. MAIN OUTCOMES AND MEASURES: The primary outcome was ICU incidence of ARDS. Secondary outcomes included assessment of clinician recognition of ARDS, the application of ventilatory management, the use of adjunctive interventions in routine clinical practice, and clinical outcomes from ARDS. RESULTS: Of 29,144 patients admitted to participating ICUs, 3022 (10.4%) fulfilled ARDS criteria. Of these, 2377 patients developed ARDS in the first 48 hours and whose respiratory failure was managed with invasive mechanical ventilation. The period prevalence of mild ARDS was 30.0% (95% CI, 28.2%-31.9%); of moderate ARDS, 46.6% (95% CI, 44.5%-48.6%); and of severe ARDS, 23.4% (95% CI, 21.7%-25.2%). ARDS represented 0.42 cases per ICU bed over 4 weeks and represented 10.4% (95% CI, 10.0%-10.7%) of ICU admissions and 23.4% of patients requiring mechanical ventilation. Clinical recognition of ARDS ranged from 51.3% (95% CI, 47.5%-55.0%) in mild to 78.5% (95% CI, 74.8%-81.8%) in severe ARDS. Less than two-thirds of patients with ARDS received a tidal volume 8 of mL/kg or less of predicted body weight. Plateau pressure was measured in 40.1% (95% CI, 38.2-42.1), whereas 82.6% (95% CI, 81.0%-84.1%) received a positive end-expository pressure (PEEP) of less than 12 cm H2O. Prone positioning was used in 16.3% (95% CI, 13.7%-19.2%) of patients with severe ARDS. Clinician recognition of ARDS was associated with higher PEEP, greater use of neuromuscular blockade, and prone positioning. Hospital mortality was 34.9% (95% CI, 31.4%-38.5%) for those with mild, 40.3% (95% CI, 37.4%-43.3%) for those with moderate, and 46.1% (95% CI, 41.9%-50.4%) for those with severe ARDS. CONCLUSIONS AND RELEVANCE: Among ICUs in 50 countries, the period prevalence of ARDS was 10.4% of ICU admissions. This syndrome appeared to be underrecognized and undertreated and associated with a high mortality rate. These findings indicate the potential for improvement in the management of patients with ARDS
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