A quick guide for student-driven community genome annotation

High quality gene models are necessary to expand the molecular and genetic tools available for a target organism, but these are available for only a handful of model organisms that have undergone extensive curation and experimental validation over the course of many years. The majority of gene models present in biological databases today have been identified in draft genome assemblies using automated annotation pipelines that are frequently based on orthologs from distantly related model organisms. Manual curation is time consuming and often requires substantial expertise, but is instrumental in improving gene model structure and identification. Manual annotation may seem to be a daunting and cost-prohibitive task for small research communities but involving undergraduates in community genome annotation consortiums can be mutually beneficial for both education and improved genomic resources. We outline a workflow for efficient manual annotation driven by a team of primarily undergraduate annotators. This model can be scaled to large teams and includes quality control processes through incremental evaluation. Moreover, it gives students an opportunity to increase their understanding of genome biology and to participate in scientific research in collaboration with peers and senior researchers at multiple institutions

Pattern Identification - A Foundation for Research in the Emphasis of Design Patterns in Systems Engineering and Knowledge Capture

Pattern Language describes the morphology and functionality of a system in the absence of design particulars. Harnessing this capability will provide the Systems Engineering discipline a means of managing the development of increasingly complex systems with increasingly distributed design teams while capturing and retaining knowledge for future generations. Pattern Language is a syntax for describing, and structurally relating, design patterns. Design patterns contextually describe the application of domain knowledge in the engineered solution to the force balance problem. The parallels between pattern recognition and application, as a fundamental stage of human learning, and pattern observation within a complex system, suggests pattern language may be a valuable tool in the capture and dissemination of knowledge. Pattern application has enjoyed considerable study over the last several decades, however much of this work has focused on the replication of design particulars. This work returns to the roots of Pattern Language and explores the utility of patterns as an architectural description and guide, and knowledge capture method, for complex system development beginning with the identification of a time proven design pattern

Launching the Grand Challenges for Ocean Conservation

The ten most pressing Grand Challenges in Oceans Conservation were identified at the Oceans Big Think and described in a detailed working document:A Blue Revolution for Oceans: Reengineering Aquaculture for SustainabilityEnding and Recovering from Marine DebrisTransparency and Traceability from Sea to Shore:  Ending OverfishingProtecting Critical Ocean Habitats: New Tools for Marine ProtectionEngineering Ecological Resilience in Near Shore and Coastal AreasReducing the Ecological Footprint of Fishing through Smarter GearArresting the Alien Invasion: Combating Invasive SpeciesCombatting the Effects of Ocean AcidificationEnding Marine Wildlife TraffickingReviving Dead Zones: Combating Ocean Deoxygenation and Nutrient Runof

Transforming Learning Through Online Storytelling: : 'Making the News' Evaluation Report

This report presents the findings from an independent evaluation undertaken by the University of Hertfordshire of the ‘Making The News project’ as it functioned within the East of England Broadband Network region (E2BN). Making the News represents a set of simple tools that allow teachers and students to rapidly produce ‘news’ stories and publish them on line. It was developed by the Centre for New Media at the Open University in conjunction with E2BNFinal Published versio

The role of visual management in collaborative integrated planning and control for engineer-to-order building systems

Visual Management is a key approach in the implementation of Lean Production. It emphasizes the importance of developing easy-to-understand visual devices for sharing knowledge within an organization. Such visual devices can play an important role in mitigating the complexity of engineer-to-order production systems. A major difficulty in managing engineer-to-order prefabricated building systems is the need to integrate planning and control of different processes, such as design, fabrication and assembly on site, in a multiple project environment. This paper reports preliminary findings on the implementation of visual devices for collaborative and integrated planning and control in a Steel Fabricator, which designs, fabricates and assembles steel structures. The aim of this paper is to understand how visual management tools can contribute to improve the effectiveness of planning and control in this environment. A set of visual devices have been used in the planning and control system in this company, including a panel that makes available information about 200 simultaneous contracts in an easy-to-understand way. The implementation of those tools has enhanced the participation of different people in the planning process from operational levels or from the different production units

Harnessing poly(ionic liquid)s for sensing applications

The interest in poly(ionic liquid)s for sensing applications is derived from their strong interactions to a variety of analytes. By combining the desirable mechanical properties of polymers with the physical and chemical properties of ILs, new materials can be created. The tunable nature of both ionic liquids and polymers allows for incredible diversity, which is exemplified in their broad applicability. In this article we examine the new field of poly(ionic liquid) sensors by providing a detailed look at the current state-of-the-art sensing devices for solvents, gases, biomolecules, pH, and anions

Harnessing Technology: new modes of technology-enhanced learning: action research, March 2009

5 action research studie

Enterprise modelling : building a product lifecycle (PLM) model as a component of the integrated vision of the enterprise

Enterprise modelling has proved to be an efficient tool to study organisations structure and facilitate decision making. The enterprise is a complex system that is required to use its processes to generate value in a given environment (concurrent, market, suppliers and humanity). We focus on three management disciplines: Product Lifecycle Management (PLM), Supply Chain Management (SCM) and Customer Relationship Management (CRM). These business processes are so intertwined that the enterprise has to concentrate on the three to attain its economic objectives. To enhance the development of PLM, SCM and CRM models, the enterprise needs to capitalise the knowledge necessary to adapt and apply modelling techniques. Knowledge Management (KM) is a key factor to give a unified enterprise vision. Firstly, we propose an integrated enterprise model depicting the interactions between PLM, SCM, CRM and KM models. But a state of the art showed that PLM models are scarce. Most of the PLM models found depends strongly on the particular case studied and can not be used with other enterprises. After defining the most important components of the PLM vision, we propose to organise these components into a formalised way. The study of SCM and CRM models proved to be helpful to structure these components. Finally the validation methodology that is to be established in our coming research works is not only to be used with the PLM model presented in this paper but with SCM and CRM models also.Product Lifecycle Management (PLM), Enterprise modelling, Enterprise systems

Tourism development potential in an insular territory : the case of Ribeira Grande in the Azores

The Autonomous Region of the Azores is one of the most sustainable destinations in the world. Being an archipelago comprised of nine small islands, quality and sustainability are critical features in the tourism sector, inducing the need for thorough and technical strategic development processes. Ribeira Grande is an important municipality in the Azores, which envisioned tourism as a strategic sector to develop when the partial liberalization of the air passenger transport sector occurred in 2015. However, this destination had little tourism maturity and competitiveness and required some structural planning work. The development of a strategic plan for tourism for the municipality of Ribeira Grande, including the selection of tourism products, is explained in detail in this article, which highlights the main challenges and results of the process.N/