Analysis and Detection of Pathological Voice using Glottal Source Features

Automatic detection of voice pathology enables objective assessment and earlier intervention for the diagnosis. This study provides a systematic analysis of glottal source features and investigates their effectiveness in voice pathology detection. Glottal source features are extracted using glottal flows estimated with the quasi-closed phase (QCP) glottal inverse filtering method, using approximate glottal source signals computed with the zero frequency filtering (ZFF) method, and using acoustic voice signals directly. In addition, we propose to derive mel-frequency cepstral coefficients (MFCCs) from the glottal source waveforms computed by QCP and ZFF to effectively capture the variations in glottal source spectra of pathological voice. Experiments were carried out using two databases, the Hospital Universitario Principe de Asturias (HUPA) database and the Saarbrucken Voice Disorders (SVD) database. Analysis of features revealed that the glottal source contains information that discriminates normal and pathological voice. Pathology detection experiments were carried out using support vector machine (SVM). From the detection experiments it was observed that the performance achieved with the studied glottal source features is comparable or better than that of conventional MFCCs and perceptual linear prediction (PLP) features. The best detection performance was achieved when the glottal source features were combined with the conventional MFCCs and PLP features, which indicates the complementary nature of the features

Improved Algorithm for Pathological and Normal Voices Identification

There are a lot of papers on automatic classification between normal and pathological voices, but they have the lack in the degree of severity estimation of the identified voice disorders. Building a model of pathological and normal voices identification, that can also evaluate the degree of severity of the identified voice disorders among students. In the present work, we present an automatic classifier using acoustical measurements on registered sustained vowels /a/ and pattern recognition tools based on neural networks. The training set was done by classifying students’ recorded voices based on threshold from the literature. We retrieve the pitch, jitter, shimmer and harmonic-to-noise ratio values of the speech utterance /a/, which constitute the input vector of the neural network. The degree of severity is estimated to evaluate how the parameters are far from the standard values based on the percent of normal and pathological values. In this work, the base data used for testing the proposed algorithm of the neural network is formed by healthy and pathological voices from German database of voice disorders. The performance of the proposed algorithm is evaluated in a term of the accuracy (97.9%), sensitivity (1.6%), and specificity (95.1%). The classification rate is 90% for normal class and 95% for pathological class

Multiple voice disorders in the same individual: Investigating handcrafted features, multi-label classification algorithms, and base-learners

Non-invasive acoustic analyses of voice disorders have been at the forefront of current biomedical research. Usual strategies, essentially based on machine learning (ML) algorithms, commonly classify a subject as being either healthy or pathologically-affected. Nevertheless, the latter state is not always a result of a sole laryngeal issue, i.e., multiple disorders might exist, demanding multi-label classification procedures for effective diagnoses. Consequently, the objective of this paper is to investigate the application of five multi-label classification methods based on problem transformation to play the role of base-learners, i.e., Label Powerset, Binary Relevance, Nested Stacking, Classifier Chains, and Dependent Binary Relevance with Random Forest (RF) and Support Vector Machine (SVM), in addition to a Deep Neural Network (DNN) from an algorithm adaptation method, to detect multiple voice disorders, i.e., Dysphonia, Laryngitis, Reinke's Edema, Vox Senilis, and Central Laryngeal Motion Disorder. Receiving as input three handcrafted features, i.e., signal energy (SE), zero-crossing rates (ZCRs), and signal entropy (SH), which allow for interpretable descriptors in terms of speech analysis, production, and perception, we observed that the DNN-based approach powered with SE-based feature vectors presented the best values of F1-score among the tested methods, i.e., 0.943, as the averaged value from all the balancing scenarios, under Saarbrücken Voice Database (SVD) and considering 20% of balancing rate with Synthetic Minority Over-sampling Technique (SMOTE). Finally, our findings of most false negatives for laryngitis may explain the reason why its detection is a serious issue in speech technology. The results we report provide an original contribution, allowing for the consistent detection of multiple speech pathologies and advancing the state-of-the-art in the field of handcrafted acoustic-based non-invasive diagnosis of voice disorders

Improved Emotion Recognition Using Gaussian Mixture Model and Extreme Learning Machine in Speech and Glottal Signals

Recently, researchers have paid escalating attention to studying the emotional state of an individual from his/her speech signals as the speech signal is the fastest and the most natural method of communication between individuals. In this work, new feature enhancement using Gaussian mixture model (GMM) was proposed to enhance the discriminatory power of the features extracted from speech and glottal signals. Three different emotional speech databases were utilized to gauge the proposed methods. Extreme learning machine (ELM) and k-nearest neighbor (kNN) classifier were employed to classify the different types of emotions. Several experiments were conducted and results show that the proposed methods significantly improved the speech emotion recognition performance compared to research works published in the literature

An Investigation of Multidimensional Voice Program Parameters in Three Different Databases for Voice Pathology Detection and Classification

Background and Objective Automatic voice-pathology detection and classification systems may help clinicians to detect the existence of any voice pathologies and the type of pathology from which patients suffer in the early stages. The main aim of this paper is to investigate Multidimensional Voice Program (MDVP) parameters to automatically detect and classify the voice pathologies in multiple databases, and then to find out which parameters performed well in these two processes. Materials and Methods Samples of the sustained vowel /a/ of normal and pathological voices were extracted from three different databases, which have three voice pathologies in common. The selected databases in this study represent three distinct languages: (1) the Arabic voice pathology database; (2) the Massachusetts Eye and Ear Infirmary database (English database); and (3) the Saarbruecken Voice Database (German database). A computerized speech lab program was used to extract MDVP parameters as features, and an acoustical analysis was performed. The Fisher discrimination ratio was applied to rank the parameters. A t test was performed to highlight any significant differences in the means of the normal and pathological samples. Results The experimental results demonstrate a clear difference in the performance of the MDVP parameters using these databases. The highly ranked parameters also differed from one database to another. The best accuracies were obtained by using the three highest ranked MDVP parameters arranged according to the Fisher discrimination ratio: these accuracies were 99.68%, 88.21%, and 72.53% for the Saarbruecken Voice Database, the Massachusetts Eye and Ear Infirmary database, and the Arabic voice pathology database, respectively

Investigation of Voice Pathology Detection and Classification on Different Frequency Regions Using Correlation Functions.

Automatic voice pathology detection and classification systems effectively contribute to the assessment of voice disorders, which helps clinicians to detect the existence of any voice pathologies and the type of pathology from which patients suffer in the early stages. This work concentrates on developing an accurate and robust feature extraction for detecting and classifying voice pathologies by investigating different frequency bands using correlation functions. In this paper, we extracted maximum peak values and their corresponding lag values from each frame of a voiced signal by using correlation functions as features to detect and classify pathological samples. These features are investigated in different frequency bands to see the contribution of each band on the detection and classification processes.Various samples of sustained vowel /a/ of normal and pathological voices were extracted from three different databases: English, German, and Arabic. A support vector machine was used as a classifier. We also performed a t test to investigate the significant differences in mean of normal and pathological samples.The best achieved accuracies in both detection and classification were varied depending on the band, the correlation function, and the database. The most contributive bands in both detection and classification were between 1000 and 8000 Hz. In detection, the highest acquired accuracies when using cross-correlation were 99.809%, 90.979%, and 91.168% in the Massachusetts Eye and Ear Infirmary, Saarbruecken Voice Database, and Arabic Voice Pathology Database databases, respectively. However, in classification, the highest acquired accuracies when using cross-correlation were 99.255%, 98.941%, and 95.188% in the three databases, respectively