ComplexWorld Position Paper

The Complex ATM Position Paper is the common research vehicle that defines the high-level, strategic scientific vision for the ComplexWorld Network. The purpose of this document is to provide an orderly and consistent scientific framework for the WP-E complexity theme. The specific objectives of the position paper are to: - analyse the state of the art within the different research areas relevant to the network, identifying the major accomplishments and providing a comprehensive set of references, including the main publications and research projects; - include a complete list of , a list of application topics, and an analysis of which techniques are best suited to each one of those applications; - identify and perform an in-depth analysis of the most promising research avenues and the major research challenges lying at the junction of ATM and complex systems domains, with particular attention to their impact and potential benefits for the ATM community; - identify areas of common interest and synergies with other SESAR activities, with special attention to the research topics covered by other WP-E networks. An additional goal for future versions of this position paper is to develop an indicative roadmap on how these research challenges should be accomplished, providing a guide on how to leverage on different aspects of the complexity research in Air Transport

Applying complexity science to air traffic management

Complexity science is the multidisciplinary study of complex systems. Its marked network orientation lends itself well to transport contexts. Key features of complexity science are introduced and defined, with a specific focus on the application to air traffic management. An overview of complex network theory is presented, with examples of its corresponding metrics and multiple scales. Complexity science is starting to make important contributions to performance assessment and system design: selected, applied air traffic management case studies are explored. The important contexts of uncertainty, resilience and emergent behaviour are discussed, with future research priorities summarised

Apparatus and method for congestion control in high speed networks

An adjustable bit rate (ABR) feedback control scheme is provided where the effects of multiloop delays and high priority traffic transmission are built into the control model. The data traffic is filtered by a low pass filter. Then, the low frequency bandwidth of the filtered traffic is measured and compared to a predetermined threshold. If the measured value exceeds the threshold, the ABR traffic flow is reduced. If the measured value is less than the threshold, the ABR traffic flow is increased. In addition, a General Prediction Control (GPC) method may be applied to the control model for optimal performance. An object of the invention is to minimize the unused link capacity subject to no congestion, where the ABR traffic is adapted to the low frequency variation of high priority traffic flow for high efficiency.Board of Regents, University of Texas Syste

The 1999 Center for Simulation of Dynamic Response in Materials Annual Technical Report

Introduction: This annual report describes research accomplishments for FY 99 of the Center for Simulation of Dynamic Response of Materials. The Center is constructing a virtual shock physics facility in which the full three dimensional response of a variety of target materials can be computed for a wide range of compressive, ten- sional, and shear loadings, including those produced by detonation of energetic materials. The goals are to facilitate computation of a variety of experiments in which strong shock and detonation waves are made to impinge on targets consisting of various combinations of materials, compute the subsequent dy- namic response of the target materials, and validate these computations against experimental data

Reverse engineering of drug induced DNA damage response signalling pathway reveals dual outcomes of ATM kinase inhibition

The DNA Damage Response (DDR) pathway represents a signalling mechanism that is activated in eukaryotic cells following DNA damage and comprises of proteins involved in DNA damage detection, DNA repair, cell cycle arrest and apoptosis. This pathway consists of an intricate network of signalling interactions driving the cellular ability to recognise DNA damage and recruit specialised proteins to take decisions between DNA repair or apoptosis. ATM and ATR are central components of the DDR pathway. The activities of these kinases are vital in DNA damage induced phosphorylational induction of DDR substrates. Here, firstly we have experimentally determined DDR signalling network surrounding the ATM/ATR pathway induced following double stranded DNA damage by monitoring and quantifying time dependent inductions of their phosphorylated forms and their key substrates. We next involved an automated inference of unsupervised predictive models of time series data to generate in silico (molecular) interaction maps. We characterized the complex signalling network through system analysis and gradual utilisation of small time series measurements of key substrates through a novel network inference algorithm. Furthermore, we demonstrate an application of an assumption-free reverse engineering of the intricate signalling network of the activated ATM/ATR pathway. We next studied the consequences of such drug induced inductions as well as of time dependent ATM kinase inhibition on cell survival through further biological experiments. Intermediate and temporal modelling outcomes revealed the distinct signaling profile associated with ATM kinase activity and inhibition and explained the underlying signalling mechanism for dual ATM functionality in cytotoxic and cytoprotective pathways

A Switch Architecture for Real-Time Multimedia Communications

In this paper we present a switch that can be used to transfer multimedia type of trafJic. The switch provides a guaranteed throughput and a bounded latency. We focus on the design of a prototype Switching Element using the new technology opportunities being offered today. The architecture meets the multimedia requirements but still has a low complexity and needs a minimum amount of hardware. A main item of this paper will be the background of the architectural design decisions made. These include the interconnection topology, buffer organization, routing and scheduling. The implementation of the switching fabric with FPGAs, allows us to experiment with switching mode, routing strategy and scheduling policy in a multimedia environment. The witching elements are interconnected in a Kautz topology. Kautz graphs have interesting properties such as: a small diametec the degree is independent of the network size, the network is fault-tolerant and has a simple routing algorithm

Application of learning algorithms to traffic management in integrated services networks.

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An Integrated Approach for Characterizing Aerosol Climate Impacts and Environmental Interactions

Aerosols exert myriad influences on the earth's environment and climate, and on human health. The complexity of aerosol-related processes requires that information gathered to improve our understanding of climate change must originate from multiple sources, and that effective strategies for data integration need to be established. While a vast array of observed and modeled data are becoming available, the aerosol research community currently lacks the necessary tools and infrastructure to reap maximum scientific benefit from these data. Spatial and temporal sampling differences among a diverse set of sensors, nonuniform data qualities, aerosol mesoscale variabilities, and difficulties in separating cloud effects are some of the challenges that need to be addressed. Maximizing the long-term benefit from these data also requires maintaining consistently well-understood accuracies as measurement approaches evolve and improve. Achieving a comprehensive understanding of how aerosol physical, chemical, and radiative processes impact the earth system can be achieved only through a multidisciplinary, inter-agency, and international initiative capable of dealing with these issues. A systematic approach, capitalizing on modern measurement and modeling techniques, geospatial statistics methodologies, and high-performance information technologies, can provide the necessary machinery to support this objective. We outline a framework for integrating and interpreting observations and models, and establishing an accurate, consistent, and cohesive long-term record, following a strategy whereby information and tools of progressively greater sophistication are incorporated as problems of increasing complexity are tackled. This concept is named the Progressive Aerosol Retrieval and Assimilation Global Observing Network (PARAGON). To encompass the breadth of the effort required, we present a set of recommendations dealing with data interoperability; measurement and model integration; multisensor synergy; data summarization and mining; model evaluation; calibration and validation; augmentation of surface and in situ measurements; advances in passive and active remote sensing; and design of satellite missions. Without an initiative of this nature, the scientific and policy communities will continue to struggle with understanding the quantitative impact of complex aerosol processes on regional and global climate change and air quality

A hybrid queueing model for fast broadband networking simulation

PhDThis research focuses on the investigation of a fast simulation method for broadband telecommunication networks, such as ATM networks and IP networks. As a result of this research, a hybrid simulation model is proposed, which combines the analytical modelling and event-driven simulation modelling to speeding up the overall simulation. The division between foreground and background traffic and the way of dealing with these different types of traffic to achieve improvement in simulation time is the major contribution reported in this thesis. Background traffic is present to ensure that proper buffering behaviour is included during the course of the simulation experiments, but only the foreground traffic of interest is simulated, unlike traditional simulation techniques. Foreground and background traffic are dealt with in a different way. To avoid the need for extra events on the event list, and the processing overhead, associated with the background traffic, the novel technique investigated in this research is to remove the background traffic completely, adjusting the service time of the queues for the background traffic to compensate (in most cases, the service time for the foreground traffic will increase). By removing the background traffic from the event-driven simulator the number of cell processing events dealt with is reduced drastically. Validation of this approach shows that, overall, the method works well, but the simulation using this method does have some differences compared with experimental results on a testbed. The reason for this is mainly because of the assumptions behind the analytical model that make the modelling tractable. Hence, the analytical model needs to be adjusted. This is done by having a neural network trained to learn the relationship between the input traffic parameters and the output difference between the proposed model and the testbed. Following this training, simulations can be run using the output of the neural network to adjust the analytical model for those particular traffic conditions. The approach is applied to cell scale and burst scale queueing to simulate an ATM switch, and it is also used to simulate an IP router. In all the applications, the method ensures a fast simulation as well as an accurate result