Magnetic resonance imaging of the brain and vocal tract:Applications to the study of speech production and language learning

The human vocal system is highly plastic, allowing for the flexible expression of language, mood and intentions. However, this plasticity is not stable throughout the life span, and it is well documented that adult learners encounter greater difficulty than children in acquiring the sounds of foreign languages. Researchers have used magnetic resonance imaging (MRI) to interrogate the neural substrates of vocal imitation and learning, and the correlates of individual differences in phonetic “talent”. In parallel, a growing body of work using MR technology to directly image the vocal tract in real time during speech has offered primarily descriptive accounts of phonetic variation within and across languages. In this paper, we review the contribution of neural MRI to our understanding of vocal learning, and give an overview of vocal tract imaging and its potential to inform the field. We propose methods by which our understanding of speech production and learning could be advanced through the combined measurement of articulation and brain activity using MRI – specifically, we describe a novel paradigm, developed in our laboratory, that uses both MRI techniques to for the first time map directly between neural, articulatory and acoustic data in the investigation of vocalisation. This non-invasive, multimodal imaging method could be used to track central and peripheral correlates of spoken language learning, and speech recovery in clinical settings, as well as provide insights into potential sites for targeted neural interventions

Evidence for Speech Sound Disorder (SSD) Assessment

Comprehensive studies on aspects related to the assessment of different biomedical parameters (acoustic and laryngeal signs and oral airflow amplitude), as well as parameters for speech disorders, articulation rate, speech inconsistency, and speech stimulability, are essential for better professional practice and to understand misarticulations in children with speech sound disorders (SSDs). Different equipments that enable noninvasive collection and analysis of data have become more common in speech-language pathology practice. Studies recently conducted by our research group have emphasized the evaluation of auditory-perceptual processing by means of assessments of central auditory processing, electrophysiology of hearing—considering that pure-tone, speech audiometry, and tympanometry are routinely used with children during the diagnostic phase and motor speech production performed by acoustic analysis of speech, electroglottography, aerodynamic measures, and ultrasound tongue imaging. This chapter presents the recent advances observed in studies with Brazilian-Portuguese speakers aiming to improve the assessment of speech sound disorders and to understand better the relationship between the different processing mechanisms involved in speech

Towards a Multimodal Silent Speech Interface for European Portuguese

Automatic Speech Recognition (ASR) in the presence of environmental noise is still a hard problem to tackle in speech science (Ng et al., 2000). Another problem well described in the literature is the one concerned with elderly speech production. Studies (Helfrich, 1979) have shown evidence of a slower speech rate, more breaks, more speech errors and a humbled volume of speech, when comparing elderly with teenagers or adults speech, on an acoustic level. This fact makes elderly speech hard to recognize, using currently available stochastic based ASR technology. To tackle these two problems in the context of ASR for HumanComputer Interaction, a novel Silent Speech Interface (SSI) in European Portuguese (EP) is envisioned.info:eu-repo/semantics/acceptedVersio

Ultrasound Visual Biofeedback and Accent Modification: Effects on Consonant and Vowel Accuracy for Mandarin English Language Learners

The number of individuals in the United States who speak languages other than English continues to increase. With the increase of language diversity comes a potential rise in communication challenges for those who speak with non-mainstream American English accents as English language learners. A portion of these individuals may elect to seek accent modification services, perhaps due to decreased intelligibility or communication breakdowns. Thus, speech-language pathologists must research and provide effective techniques to enhance intelligibility of all American English speakers for optimal communication. Few approaches employ a variety of treatment methods to improve speech sound accuracy, naturalness and intelligibility to target accent modification. One of these methods is ultrasound biofeedback therapy. Ultrasound therapy relies on visual feedback for remediation of speech sound production errors for those with various etiologies and diagnoses. A single-subject ABAB withdrawal design was employed with two native Mandarin speakers to examine the effect of incorporating ultrasound visual biofeedback in the treatment of consonant and vowel targets as measured by perceptual, acoustic and visual analyses

Models and analysis of vocal emissions for biomedical applications: 5th International Workshop: December 13-15, 2007, Firenze, Italy

The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies. The Workshop has the sponsorship of: Ente Cassa Risparmio di Firenze, COST Action 2103, Biomedical Signal Processing and Control Journal (Elsevier Eds.), IEEE Biomedical Engineering Soc. Special Issues of International Journals have been, and will be, published, collecting selected papers from the conference

3-D Oropharyngeal Airway Analysis of Different Antero-Posterior and Vertical Craniofacial Skeletal Patterns in Children and Adolescents

Sleep apnea disorder has recently emerged as a significant public health issue. While the prevalence of obesity is on the rise among children, it is one of the main risk factors associated with apnea. Upper airway dimensions and morphology seem to be major components of obstructive sleep apnea (OSA) and can be affected by different craniofacial patterns. The purpose of this retrospective, cross-sectional pilot study is to correlate gender, Body Mass Index, risk for OSA, neck circumference, and 3-D oropharyngeal airway dimensions in children and adolescents with different antero-posterior (AP) and vertical craniofacial skeletal patterns. A total of 86 pre-orthodontic treatment records in the age group of 8-16 years were analyzed. 3-D volumetric skeletal tracing and oropharyngeal airway measurements were completed for each scan. Each subject was classified into AP Classes I, II, and III groups; vertical Normodivergent, Hypodivergent, and Hyperdivergent groups; and combined AP-vertical subgroups. Oropharyngeal airway measurements included the total oropharyngeal airway volume, minimum cross-section area, depth, width, and perimeter. Mean, standard deviation, and Pearson\u27s correlation coefficient were performed to evaluate the relationships among variables. There were one or more correlations, but not all, between gender, Body Mass Index, risk for OSA, neck circumference, and 3-D oropharyngeal airway dimensions in children and adolescents among the AP groups, vertical groups, and nine craniofacial subgroups (P \u3c 0.05 and P \u3c 0.01). This investigation aimed to determine whether patients with certain skeletal deficiencies are predisposed to upper airway obstruction. Early identification and management of airway problems in children and adolescents may prevent or minimize the sequelae and adverse dental implications of obstructive sleep apnea. Our small, young groups of sample were mainly in the healthy weight category with normal size neck circumference. Therefore, this limited our overall findings. Currently, sleep disorders are not well researched and understood. Long-term goal of our study is to further investigate this study in larger sample size taken into considerations predisposing factors (i.e. abnormal neural regulation and intrinsic muscle weakness) and pathologic conditions (allergies, polyps, and tumors). The physiology of the airway, influenced by these confounding factors, has an essential role in determining whether patients with certain skeletal deficiencies are predisposed to upper airway obstruction. Sleep apnea is a complex phenomenon that warrants further research regarding the physiology and anatomy of the airway and craniofacial structures

Models and Analysis of Vocal Emissions for Biomedical Applications

The International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications (MAVEBA) came into being in 1999 from the particularly felt need of sharing know-how, objectives and results between areas that until then seemed quite distinct such as bioengineering, medicine and singing. MAVEBA deals with all aspects concerning the study of the human voice with applications ranging from the neonate to the adult and elderly. Over the years the initial issues have grown and spread also in other aspects of research such as occupational voice disorders, neurology, rehabilitation, image and video analysis. MAVEBA takes place every two years always in Firenze, Italy. This edition celebrates twenty years of uninterrupted and succesfully research in the field of voice analysis

PRELIMINARY FINDINGS OF A POTENZIATED PIEZOSURGERGICAL DEVICE AT THE RABBIT SKULL

The number of available ultrasonic osteotomes has remarkably increased. In vitro and in vivo studies have revealed differences between conventional osteotomes, such as rotating or sawing devices, and ultrasound-supported osteotomes (Piezosurgery®) regarding the micromorphology and roughness values of osteotomized bone surfaces. Objective: the present study compares the micro-morphologies and roughness values of osteotomized bone surfaces after the application of rotating and sawing devices, Piezosurgery Medical® and Piezosurgery Medical New Generation Powerful Handpiece. Methods: Fresh, standard-sized bony samples were taken from a rabbit skull using the following osteotomes: rotating and sawing devices, Piezosurgery Medical® and a Piezosurgery Medical New Generation Powerful Handpiece. The required duration of time for each osteotomy was recorded. Micromorphologies and roughness values to characterize the bone surfaces following the different osteotomy methods were described. The prepared surfaces were examined via light microscopy, environmental surface electron microscopy (ESEM), transmission electron microscopy (TEM), confocal laser scanning microscopy (CLSM) and atomic force microscopy. The selective cutting of mineralized tissues while preserving adjacent soft tissue (dura mater and nervous tissue) was studied. Bone necrosis of the osteotomy sites and the vitality of the osteocytes near the sectional plane were investigated, as well as the proportion of apoptosis or cell degeneration. Results and Conclusions: The potential positive effects on bone healing and reossification associated with different devices were evaluated and the comparative analysis among the different devices used was performed, in order to determine the best osteotomes to be employed during cranio-facial surgery

Models and Analysis of Vocal Emissions for Biomedical Applications

The International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications (MAVEBA) came into being in 1999 from the particularly felt need of sharing know-how, objectives and results between areas that until then seemed quite distinct such as bioengineering, medicine and singing. MAVEBA deals with all aspects concerning the study of the human voice with applications ranging from the newborn to the adult and elderly. Over the years the initial issues have grown and spread also in other fields of research such as occupational voice disorders, neurology, rehabilitation, image and video analysis. MAVEBA takes place every two years in Firenze, Italy. This edition celebrates twenty-two years of uninterrupted and successful research in the field of voice analysis

AN ARTICULATORY-ACOUSTIC INVESTIGATION OF TIMING AND COORDINATION IN THE FLUENT SPEECH OF PEOPLE WHO STAMMER

This thesis investigates Wingate’s Fault-Line hypothesis (1988) which suggests that disfluencies in people who stammer (PWS) result from a deficit in transition from consonant to vowel (CV) thereby implying that stammering as a motor-control disorder would affect transitions even when not perceptually salient. To test this proposal, we explored the perceptually fluent speech of PWS using instrumental analysis (ultrasound and acoustic) to determine the underlying pervasiveness of disfluencies in this group as compared to people who do not stammer (PNS). Following fluency screening of recorded utterances, we applied acoustic and articulatory analysis techniques to perceptually fluent utterances of 9 PWS and 9 typical speakers in order to identify indicators of disfluency in the transition from syllable onsets to the following vowel. Measures of acoustic duration, locus equation and formant slope offer insights into timing and degree of coarticulation. The articulatory ultrasound tongue imaging technique moreover provides kinematic information of the tongue. A novel technique was applied to dynamically analyse and quantify the tongue kinematics in transition. This allowed us to treat the perceptually fluent speech of PWS as an ongoing time-situated process. Both acoustic and articulatory findings indicate by-group differences in timing, whereby PWS are overall slower and more variable in the execution of CV transitions when compared to typical speakers (PNS). The findings from both instrumental approaches also indicate differences in coordination, suggesting that PWS coarticulate to a lesser extent than PNS. Overall, these findings suggest that PWS exhibit a global deficit in CV transition that can be observed in perceptually fluent as well as stammered speech. This is in keeping with the predictions of Wingate’s Fault-Line hypothesis. iv The fact that the conclusions from the acoustic and articulatory measures are coherent, shows that acoustic measures may be sufficient to act as a proxy for articulatory measures