The Surface of Acceptability in Virtual Faces

This paper explores the surface properties of skin and eyes and their importance in the acceptance and success of a digital human face, specifically in relation to the uncanny valley. The uncanny valley hypothesis states that as a human representation approaches photo-realism, subtle differences from reality become unsettling. Recent studies suggest that the uncanny valley could exist over a far greater range, affecting abstract human representations as well. These competing findings are explored by analyzing how changes to the surface of a digital character affect its level of acceptance. A female facial model is used as a base to compare a spectrum of different simulated real-world materials. The variations range from materials that are nearly identical to human skin, to those that are completely divergent from it, thus unnatural. After studying this catalogue of materials, it is concluded that given the right conditions, the uncanny valley can occur when facial representations are very near realism, as well as when human-likeness is quite distant from reality

Facial Age Analysis using an Absorptive Rough Laminar Light Scattering Model

Facial aging research concerns the way aging affects a person’s appearance and how we can use knowledge of this process. It has been an interesting topic for fields such as human perception, pattern recognition, computer vision, graphics, and skin optics. Most studies acknowledge that facial appearance changes with age. As a person grows older, certain characteristics of their skin will change, notably the light scattering. If a model is used to predict a person’s skin light scattering, its parameter(s) may be used to predict the age of its owner. The aim of this thesis is to observe whether a light scattering model parameter is suitable to be used as an age estimator/classifier. This is done by investigating and analyzing the relationship between the parameter of an analytical-based light scattering model and skins of various ages. In the end, this thesis has shown that the parameter(s) for an analytical-based light scattering model can be used as an alternative method for estimating/classifying a person’s age

Possible ways to improve the comfort, fit and visual performance of swimming goggles

The primary aim of this thesis was to provide a comprehensive evaluation of the human face so that it can be used to improve the design of swimming goggles with regards to comfort and fit. The secondary aim was concerned with vision and was to identify whether a curved lens could be plausible for use in a performance racing goggle. [Continues.

Quantification of the Environmental Solar Ultraviolet Radiation Field at the Human Eye and the Investigation of Peripherally Focused Rays.

The increase of terrestrial solar ultraviolet radiation (UVR) due to the reduction of the ozone layer has promoted a variety of research into establishing the impact of this elevated potential dose of UVR on biological tissues. Anterior ocular tissues such as the cornea have been found to be susceptible to damage by terrestrial solar UVR and diseases such as pterygium are commonly thought to be a direct result of absorbed UVR at the nasal limbus. There is a need for more accurate quantification and localisation of incident UVR at the anterior ocular surface. A novel solar blind photodiode sensor array system has been designed, constructed and tested for this purpose. The distribution of terrestrial solar UVR across the palpebral fissure for two test subjects has been quantified for a range of head orientations under different environmental conditions. The results herein outline the protection provided by different facial anatomies and the methodology has been proven through the repeatability of measurements over a range of cardinal point orientations. Added to the ambient terrestrial irradiance across the palpebral fissure, the phenomenon of Peripheral Light Focusing (PLF) has been investigated. Through the incorporation of modeling software and an anatomically based artificial eye, a novel fibre optic method has been developed to measure the corneal transmission in vivo

A Van Gogh inspired 3D Shader Methodology

This study develops an approach to developing surface shading for computer-generated 3D head models that adapts aesthetics from the post-impressionist portrait painting style of Vincent Van Gogh. This research is an attempt to reconcile a 2D expressionist style of painting and 3D digital computer generated imagery. The focus of this research is on developing a surface shading methodology for creating 3D impasto painterly renderings informed by Van Gogh’s self-portrait paintings. Visual analysis of several of Van Gogh’s self-portraits reveal the characteristics of his overall rendering style that are essential in designing methods for shading and texturing 3D head models. A method for shading is proposed using existing surfacing and rendering tools to create 3D digital heads rendered in Van Gogh’s style. The designed shading methodology describes procedures that generate brushstroke patterns. User controls for brushstroke profile, size, color and direction are provided to allow variations in the brushstroke patterns. These patterns are used to define thick oil paint surface properties for 3D digital models. A discussion of the range of results achieved using the designed shading methodology reveal the variations in the rendering style that can be achieved, which reflects a wide range of expressive 3D portrait rendering styles. Therefore, this study is useful in understanding Van Gogh’s expressive portrait painting style and in applying the essence of his work to synthesized 3D portraits

Phenomenological modeling of image irradiance for non-Lambertian surfaces under natural illumination.

Various vision tasks are usually confronted by appearance variations due to changes of illumination. For instance, in a recognition system, it has been shown that the variability in human face appearance is owed to changes to lighting conditions rather than person\u27s identity. Theoretically, due to the arbitrariness of the lighting function, the space of all possible images of a fixed-pose object under all possible illumination conditions is infinite dimensional. Nonetheless, it has been proven that the set of images of a convex Lambertian surface under distant illumination lies near a low dimensional linear subspace. This result was also extended to include non-Lambertian objects with non-convex geometry. As such, vision applications, concerned with the recovery of illumination, reflectance or surface geometry from images, would benefit from a low-dimensional generative model which captures appearance variations w.r.t. illumination conditions and surface reflectance properties. This enables the formulation of such inverse problems as parameter estimation. Typically, subspace construction boils to performing a dimensionality reduction scheme, e.g. Principal Component Analysis (PCA), on a large set of (real/synthesized) images of object(s) of interest with fixed pose but different illumination conditions. However, this approach has two major problems. First, the acquired/rendered image ensemble should be statistically significant vis-a-vis capturing the full behavior of the sources of variations that is of interest, in particular illumination and reflectance. Second, the curse of dimensionality hinders numerical methods such as Singular Value Decomposition (SVD) which becomes intractable especially with large number of large-sized realizations in the image ensemble. One way to bypass the need of large image ensemble is to construct appearance subspaces using phenomenological models which capture appearance variations through mathematical abstraction of the reflection process. In particular, the harmonic expansion of the image irradiance equation can be used to derive an analytic subspace to represent images under fixed pose but different illumination conditions where the image irradiance equation has been formulated in a convolution framework. Due to their low-frequency nature, irradiance signals can be represented using low-order basis functions, where Spherical Harmonics (SH) has been extensively adopted. Typically, an ideal solution to the image irradiance (appearance) modeling problem should be able to incorporate complex illumination, cast shadows as well as realistic surface reflectance properties, while moving away from the simplifying assumptions of Lambertian reflectance and single-source distant illumination. By handling arbitrary complex illumination and non-Lambertian reflectance, the appearance model proposed in this dissertation moves the state of the art closer to the ideal solution. This work primarily addresses the geometrical compliance of the hemispherical basis for representing surface reflectance while presenting a compact, yet accurate representation for arbitrary materials. To maintain the plausibility of the resulting appearance, the proposed basis is constructed in a manner that satisfies the Helmholtz reciprocity property while avoiding high computational complexity. It is believed that having the illumination and surface reflectance represented in the spherical and hemispherical domains respectively, while complying with the physical properties of the surface reflectance would provide better approximation accuracy of image irradiance when compared to the representation in the spherical domain. Discounting subsurface scattering and surface emittance, this work proposes a surface reflectance basis, based on hemispherical harmonics (HSH), defined on the Cartesian product of the incoming and outgoing local hemispheres (i.e. w.r.t. surface points). This basis obeys physical properties of surface reflectance involving reciprocity and energy conservation. The basis functions are validated using analytical reflectance models as well as scattered reflectance measurements which might violate the Helmholtz reciprocity property (this can be filtered out through the process of projecting them on the subspace spanned by the proposed basis, where the reciprocity property is preserved in the least-squares sense). The image formation process of isotropic surfaces under arbitrary distant illumination is also formulated in the frequency space where the orthogonality relation between illumination and reflectance bases is encoded in what is termed as irradiance harmonics. Such harmonics decouple the effect of illumination and reflectance from the underlying pose and geometry. Further, a bilinear approach to analytically construct irradiance subspace is proposed in order to tackle the inherent problem of small-sample-size and curse of dimensionality. The process of finding the analytic subspace is posed as establishing a relation between its principal components and that of the irradiance harmonics basis functions. It is also shown how to incorporate prior information about natural illumination and real-world surface reflectance characteristics in order to capture the full behavior of complex illumination and non-Lambertian reflectance. The use of the presented theoretical framework to develop practical algorithms for shape recovery is further presented where the hitherto assumed Lambertian assumption is relaxed. With a single image of unknown general illumination, the underlying geometrical structure can be recovered while accounting explicitly for object reflectance characteristics (e.g. human skin types for facial images and teeth reflectance for human jaw reconstruction) as well as complex illumination conditions. Experiments on synthetic and real images illustrate the robustness of the proposed appearance model vis-a-vis illumination variation. Keywords: computer vision, computer graphics, shading, illumination modeling, reflectance representation, image irradiance, frequency space representations, {hemi)spherical harmonics, analytic bilinear PCA, model-based bilinear PCA, 3D shape reconstruction, statistical shape from shading

Experimental imaging of asthma progression and therapeutic response in mouse lung models

Asthma ist eine Erkrankung die das komplette Immunsystems involviert, ein System so komplex, dass es sich nur unzureichend in-vitro studieren lässt. Daher haben sich Mausmodelle als ein unverzichtbares Werkzeug in der präklinischen Asthmaforschung etabliert. Da es sich weiterhin bei Asthma um eine Erkrankung handelt, die durch eine schnelle Änderung der Symptome gekennzeichnet ist, wäre longitudinale vorzugsweise nicht-invasive Bildgebung, insbesondere bei der Entwicklung und Bewertung neuer Therapiekonzepte von großem Interesse. Nachteilig hingegen ist, dass die Darstellung der Mauslunge in der Praxis auf Grund der Größe des Organs und, im Falle einer in vivo Bildgebung, durch die Bewegung des Brustkorbes sich als äußerst schwierig herausstellt. Die Vielzahl der Luft-Gewebe-Grenzflächen erzeugt starke Streuung in der optischen Bildgebung, der große Hohlraum der Lunge verursacht Suszeptibilitätsartefakte bei der MRT und die Rippen erschweren eine Ultraschallbildgebung. Aus diesen Gründen besteht ein großer Bedarf an neuen Bildgebungsverfahren, um die durch Asthma verursachten anatomischen, funktionalen und molekularen Veränderungen darstellen zu können. Um die Schwierigkeiten in der Lungenbildgebung bei Mäusen zu umgehen, habe ich mich auf drei wesentliche Bildgebungsstrategien fokussiert: A) anatomische Bildgebung durch “inline free propagation phase contrast computed tomography”, B) direkte Messung der Lungenfunktion durch “low dose planar cinematic x-ray imaging” und C) funktionale Bildgebung mit Hilfe der „near infrared fluorescence imaging“ in Kombination mit Antikörpern, die mit einem Fluoreszenzfarbstoff markiert wurden, oder “smart probes”, die in Gegenwart von Entzündungen aktiviert werden. Durch die Anwendung von “phase contrast computed tomography” für die anatomische Bildgebung war ich in der Lage morphologische Veränderung des Lungengewebes zu quantifizieren, indem ich lokal das Verhältnis zwischen Weichgewebe und Luft, das Zusammenziehen der Luftwege sowie das Anschwellen der Bronchialwände im asthmatischen Lungengewebe ausgewertet habe. Diese Parameter erlaubten es zwischen Mäusen von Asthmamodellen unterschiedlicher Schweregrade, therapierten und gesunden Mäusen zu unterscheiden. Zusätzlich ermöglichte diese Technik die Darstellung intra-tracheal applizierter Bariumsulfat markierter Makrophagen im Lungengewebe. Dies stellt meines Wissens die erste Kombination einer funktionalisierten Kontrastierung und hochauflösender Lungenbildgebung mittels CT unter in vivo ähnlichen Bedingungen dar. Um diese Ergebnisse mit dem Grad der asthmabedingten Kurzatmigkeit zu korrelieren, habe ich eine einfache und verlässige Methode entwickelt die es, basierend auf 2D Röntgen-videos niedriger Röntgendosis (~6,5mGy) erlaubt, in narkotisierten Mäusen die Lungenfunktion zu bewerten. Mit Hilfe dieser neuen Methode gelang es mir charakteristische Unterschiede in der Lungenfunktion von asthmatischen, therapierten und gesunden Mäusen in vivo über die Zeit nachzuweisen, und diese Resultate mit den Ergebnissen von CT und Histologie zu korrelieren. Das Verfahren wird derzeit von mir für die Anwendung an frei beweglichen und nicht narkotisierten Mäusen weiterentwickelt. Dies sollte zu einer deutlichen Stressreduktion für die Maus bei der Untersuchung führen und somit, vor allem in Asthma, im Gegensatz zu etablierten Verfahren wie Plethysmographie, die Erhebung validerer Messdaten erlauben. Mit Hilfe von „near infrared fluorescence imaging“ konnten wir in vivo und longitudinal erfolgreich verschiedene durch Asthma ausgelöste molekulare Veränderungen in der Mauslunge verfolgen. Erstens erlaubte die Verwendung einer neuen Polyglyzerol Probe mit dendritischer Struktur (MN2012) die spezifisch an Selektine bindet, die Darstellung der durch Asthma verursachten Entzündung der Lunge. Im Zuge dessen konnten wir nachweisen, dass sich MN2012  zur Darstellung von Enzymkinetiken bei Entzündungsreaktionen durch eine schnellere Kinetik und höher Spezifität als kommerziell erhältliche Proben auszeichnet. Zweitens haben wir gezeigt, dass in Kombination mit einem Fluoreszenz markiertem Antikörper gegen SiglecF, einem Antigen das hauptsächlich auf Eosinophilen exprimiert ist, Eosinophilie in asthmatischen Mäusen verfolgt und der Effekt einer Dexamethason Behandlung  ebenso dargestellt werden kann. Drittens konnten wir den Verbleib inhalierter fluoreszierender Nanopartikel in der Lunge der Maus in vivo untersuchen und dabei nachweisen, dass diese hauptsächlich von endogenen Makrophagen im Lungengewebe aufgenommen werden. Alle diese Techniken wurden gegeneinander und mittels histologischer Analyse und Fluoreszenzmikroskopie korreliert und validiert.  Zusammenfassend bilden die in meiner Dissertation entwickelten Lungenbildgebungsstrategien für Asthmamausmodelle eine Bildgebungsplattform, um sowohl spezifische Effekte in asthmatischen Mäusen unterschiedlichen Schweregrades als auch die Auswirkungen neuer Therapien abzubilden und im Detail zu untersuchen

Head tracking two-image 3D television displays

The research covered in this thesis encompasses the design of novel 3D displays, a consideration of 3D television requirements and a survey of autostereoscopic methods is also presented. The principle of operation of simple 3D display prototypes is described, and design of the components of optical systems is considered. A description of an appropriate non-contact infrared head tracking method suitable for use with 3D television displays is also included. The thesis describes how the operating principle of the displays is based upon a twoimage system comprising a pair of images presented to the appropriate viewers' eyes. This is achieved by means of novel steering optics positioned behind a direct view liquid crystal display (LCD) that is controlled by a head position tracker. Within the work, two separate prototypes are described, both of which provide 3D to a single viewer who has limited movement. The thesis goes on to describe how these prototypes can be developed into a multiple-viewer display that is suitable for television use. A consideration of 3D television requirements is documented showing that glassesfree viewing (autostereoscopic), freedom of viewer movement and practical designs are important factors for 3D television displays. The displays are novel in design in several important aspects that comply with the requirements for 3D television. Firstly they do not require viewers to wear special glasses, secondly the displays allow viewers to move freely when viewing and finally the design of the displays is practical with a housing size similar to modem television sets and a cost that is not excessive. Surveys of other autostereoscopic methods included within the work suggest that no contemporary 3D display offers all of these important factors

Ultrasound Imaging

This book provides an overview of ultrafast ultrasound imaging, 3D high-quality ultrasonic imaging, correction of phase aberrations in medical ultrasound images, etc. Several interesting medical and clinical applications areas are also discussed in the book, like the use of three dimensional ultrasound imaging in evaluation of Asherman's syndrome, the role of 3D ultrasound in assessment of endometrial receptivity and follicular vascularity to predict the quality oocyte, ultrasound imaging in vascular diseases and the fetal palate, clinical application of ultrasound molecular imaging, Doppler abdominal ultrasound in small animals and so on