113 research outputs found

    Gradual Synchronization

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    A synchronization solution is developed in order to allow finer grained segmentation of clock domains on a chip. This solution incorporates computation into the synchronization overhead time and is called Gradual Synchronization. With Gradual Synchronization as a synchronization method the design space of a chip could easily mix both asynchronous and synchronous blocks of logic, paving the way for wider use of asynchronous logic design

    Biological rhythms, chronodisruption and chrono-enhancement: The role of physical activity as synchronizer in correcting steroids circadian rhythm in metabolic dysfunctions and cancer

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    This is an Accepted Manuscript of an article published by Taylor & Francis in Chronobiology International on 28 June 2018, available online: http://www.tandfonline.com/10.1080/07420528.2018.1475395.Rhythms can be observed at all levels of the biologic integration in humans. The observation that a biological or physiological variable shows a circadian rhythm can be explained by several multifactorial systems including external (exogenous), internal (endogenous) and psychobiological (lifestyle) mechanisms. Our body clock can be synchronized with the environment by external factors, called “synchronizers”, i.e. the light–dark cycle, but it is also negatively influenced by some pathological conditions or factors, called “chronodisruptors,” i.e. aging or low physical activity (PA). The desynchronization of a 24-h rhythm in a chronic manner has been recently defined “chronodisruption” or “circadian disruption.” A very large number of hormonal variables, such as adrenal and gonadal stress steroids, are governed by circadian rhythmicity. Such hormones, in normal conditions, show a peak in the first part of the day, while their typical diurnal fluctuations are totally out of sync in subjects affected by cancer or metabolic diseases, such as obesity, diabetes and metabolic syndrome. In general, a flatter slope with altered peaks in cortisol and testosterone circadian rhythms has been observed in pathological individuals. PA, specifically chronic exercise, seems to play a key role as synchronizer for the whole circadian system in such pathologies even if specific data on steroids circadian pattern are still sparse and contradictory. Recently, it has been proposed that low-intensity chronic PA could be an effective intervention to decrease morning cortisol levels in pathological subjects. The standardization of all confounding factors is needed to reach more clear evidence-based results

    Design of robust asynchronous reconfigurable controllers for parallel synchronization using embedded graphs

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    PhD Thesis: This is a revised version received 24/5/16. The definitive version is the print copy in the Research Reserve Collection of the University LibrarySynchronization is a key System-on-Chip (SoC) design issue in modern technologies. As the number of operating points under consideration increases, specifications which are capable of altering key parameters such as the time available for synchronization and Mean Time Between Failures (MTBF) in response to input from the user/system become desirable. This thesis explores how a combination of parallelism and scheduling, referred to as wagging, can be utilized to construct schedulers for synchronizer designs which are capable of pooling the gain-bandwidth products of their composite devices, in order to satisfy this requirement. In this work, we explore the ways in which the areas of graph theory and reconfigurable hardware design can be applied to generate both combinational and sequential scheduler designs, which satisfy the behavior requirement above. Further to this point, this work illustrates that such a scheduler is primarily comprised of an interrupt subsystem, and a reconfigurable token ring. This thesis explores how both of these components can be controlled in absence of a clock signal, as well as the design challenges inherent to each part. The final noteworthy issue in this study is with regard to the flow control of data in a parallel synchronizer that incorporates a First-In First-Out (FIFO) buffer to decouple the reading and writing operations from each other. Such a structure incurs penalties if the data rates on both sides are not well matched. This work presents a method by which combinations of serial and parallel reading operations are used to minimize this mismatch

    Transdisciplinary unifying implications of circadian findings in the 1950s

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    A few puzzles relating to a small fraction of my endeavors in the 1950s are summarized herein, with answers to a few questions of the Editor-in-Chief, to suggest that the rules of variability in time complement the rules of genetics as a biological variability in space. I advocate to replace truisms such as a relative constancy or homeostasis, that have served bioscience very well for very long. They were never intended, however, to lower a curtain of ignorance over everyday physiology. In raising these curtains, we unveil a range of dynamics, resolvable in the data collection and as-one-goes analysis by computers built into smaller and smaller devices, for a continued self-surveillance of the normal and for an individualized detection of the abnormal. The current medical art based on spotchecks interpreted by reference to a time-unqualified normal range can become a science of time series with tests relating to the individual in inferential statistical terms. This is already doable for the case of blood pressure, but eventually should become possible for many other variables interpreted today only based on the quicksand of clinical trials on groups. These ignore individual differences and hence the individual's needs. Chronomics (mapping time structures) with the major aim of quantifying normalcy by dynamic reference values for detecting earliest risk elevation, also yields the dividend of allowing molecular biology to focus on the normal as well as on the grossly abnormal

    Study of efficient transmission and reception of image-type data using millimeter waves

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    Evaluation of signal processing and modulation techniques for transmission and reception of image type data via millimeter wave relay satellite

    Doctor of Philosophy

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    dissertationPortable electronic devices will be limited to available energy of existing battery chemistries for the foreseeable future. However, system-on-chips (SoCs) used in these devices are under a demand to offer more functionality and increased battery life. A difficult problem in SoC design is providing energy-efficient communication between its components while maintaining the required performance. This dissertation introduces a novel energy-efficient network-on-chip (NoC) communication architecture. A NoC is used within complex SoCs due it its superior performance, energy usage, modularity, and scalability over traditional bus and point-to-point methods of connecting SoC components. This is the first academic research that combines asynchronous NoC circuits, a focus on energy-efficient design, and a software framework to customize a NoC for a particular SoC. Its key contribution is demonstrating that a simple, asynchronous NoC concept is a good match for low-power devices, and is a fruitful area for additional investigation. The proposed NoC is energy-efficient in several ways: simple switch and arbitration logic, low port radix, latch-based router buffering, a topology with the minimum number of 3-port routers, and the asynchronous advantages of zero dynamic power consumption while idle and the lack of a clock tree. The tool framework developed for this work uses novel methods to optimize the topology and router oorplan based on simulated annealing and force-directed movement. It studies link pipelining techniques that yield improved throughput in an energy-efficient manner. A simulator is automatically generated for each customized NoC, and its traffic generators use a self-similar message distribution, as opposed to Poisson, to better match application behavior. Compared to a conventional synchronous NoC, this design is superior by achieving comparable message latency with half the energy

    Digital desing for neuroporphic bio-inspired vision processing.

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    Artificial Intelligence (AI) is an exciting technology that flourished in this century. One of the goals for this technology is to give learning ability to computers. Currently, machine intelligence surpasses human intelligence in specific domains. Besides some conventional machine learning algorithms, Artificial Neural Networks (ANNs) is arguably the most exciting technology that is used to bring this intelligence to the computer world. Due to ANN’s advanced performance, increasing number of applications that need kind of intelligence are using ANN. Neuromorphic engineers are trying to introduce bio-inspired hardware for efficient implementation of neural networks. This hardware should be able to simulate a vast number of neurons in real-time with complex synaptic connectivity while consuming little power. The work that has been done in this thesis is hardware oriented, so it is necessary for the reader to have a good understanding of the hardware that is used for developments in this thesis. In this chapter, we provide a brief overview of the hardware platforms that are used in this thesis. Afterward, we explain briefly the contributions of this thesis to the bio-inspired processing research line

    DeepDeMod: BPSK Demodulation Using Deep Learning Over Software-Defined Radio

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    In wireless communication, signal demodulation under non-ideal conditions is one of the important research topic. In this paper, a novel non-coherent binary phase shift keying demodulator based on deep neural network, namely DeepDeMod, is proposed. The proposed scheme makes use of neural network to decode the symbols from the received sampled signal. The proposed scheme is developed to demodulate signal under fading channel with additive white Gaussian noise along with hardware imperfections, such as phase and frequency offset. The time varying nature of hardware imperfections and channel poses a additional challenge in signal demodulation. In order to address this issue, additionally we propose transfer learning based DeepDeMod scheme. Pilot symbols along with data is transmitted in a packet which is used to learn the time varying parameters from the pilot reception followed by data demodulation. Results show that compared with the conventional demodulators and other machine learning based demodulators, our proposed DeepDeMod provides significantly better performance in term of bit error rate. We also implement the proposed DeepDeMod on software defined radio and present the experimental results
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