The "Federica" hand: a simple, very efficient prothesis

Hand prostheses partially restore hand appearance and functionalities. Not everyone can afford expensive prostheses and many low-cost prostheses have been proposed. In particular, 3D printers have provided great opportunities by simplifying the manufacturing process and reducing costs. Generally, active prostheses use multiple motors for fingers movement and are controlled by electromyographic (EMG) signals. The "Federica" hand is a single motor prosthesis, equipped with an adaptive grasp and controlled by a force-myographic signal. The "Federica" hand is 3D printed and has an anthropomorphic morphology with five fingers, each consisting of three phalanges. The movement generated by a single servomotor is transmitted to the fingers by inextensible tendons that form a closed chain; practically, no springs are used for passive hand opening. A differential mechanical system simultaneously distributes the motor force in predefined portions on each finger, regardless of their actual positions. Proportional control of hand closure is achieved by measuring the contraction of residual limb muscles by means of a force sensor, replacing the EMG. The electrical current of the servomotor is monitored to provide the user with a sensory feedback of the grip force, through a small vibration motor. A simple Arduino board was adopted as processing unit. The differential mechanism guarantees an efficient transfer of mechanical energy from the motor to the fingers and a secure grasp of any object, regardless of its shape and deformability. The force sensor, being extremely thin, can be easily embedded into the prosthesis socket and positioned on both muscles and tendons; it offers some advantages over the EMG as it does not require any electrical contact or signal processing to extract information about the muscle contraction intensity. The grip speed is high enough to allow the user to grab objects on the fly: from the muscle trigger until to the complete hand closure, "Federica" takes about half a second. The cost of the device is about 100 US$. Preliminary tests carried out on a patient with transcarpal amputation, showed high performances in controlling the prosthesis, after a very rapid training session. The "Federica" hand turned out to be a lightweight, low-cost and extremely efficient prosthesis. The project is intended to be open-source: all the information needed to produce the prosthesis (e.g. CAD files, circuit schematics, software) can be downloaded from a public repository. Thus, allowing everyone to use the "Federica" hand and customize or improve it

Towards electrodeless EMG linear envelope signal recording for myo-activated prostheses control

After amputation, the residual muscles of the limb may function in a normal way, enabling the electromyogram (EMG) signals recorded from them to be used to drive a replacement limb. These replacement limbs are called myoelectric prosthesis. The prostheses that use EMG have always been the first choice for both clinicians and engineers. Unfortunately, due to the many drawbacks of EMG (e.g. skin preparation, electromagnetic interferences, high sample rate, etc.); researchers have aspired to find suitable alternatives. One proposes the dry-contact, low-cost sensor based on a force-sensitive resistor (FSR) as a valid alternative which instead of detecting electrical events, detects mechanical events of muscle. FSR sensor is placed on the skin through a hard, circular base to sense the muscle contraction and to acquire the signal. Similarly, to reduce the output drift (resistance) caused by FSR edges (creep) and to maintain the FSR sensitivity over a wide input force range, signal conditioning (Voltage output proportional to force) is implemented. This FSR signal acquired using FSR sensor can be used directly to replace the EMG linear envelope (an important control signal in prosthetics applications). To find the best FSR position(s) to replace a single EMG lead, the simultaneous recording of EMG and FSR output is performed. Three FSRs are placed directly over the EMG electrodes, in the middle of the targeted muscle and then the individual (FSR1, FSR2 and FSR3) and combination of FSR (e.g. FSR1+FSR2, FSR2-FSR3) is evaluated. The experiment is performed on a small sample of five volunteer subjects. The result shows a high correlation (up to 0.94) between FSR output and EMG linear envelope. Consequently, the usage of the best FSR sensor position shows the ability of electrode less FSR-LE to proportionally control the prosthesis (3-D claw). Furthermore, FSR can be used to develop a universal programmable muscle signal sensor that can be suitable to control the myo-activated prosthesis

Design and Implementation of Active Elbow Orthosis

Práce prezentuje nový přístup k designu motorového rehabilitačního zařízení – aktivní loketní ortézy (ALO) – inspirovaný principy robotických exoskeletonů. Zařízení je v současnosti navrženo pro loketní kloub s možností modifikace pro další klouby. ALO snímá pohyb pacienta pomocí tenzometrického siloměru, čehož následně využívá pro řízení pohonů, které ovládají předloketní část rámu ortézy. Úroveň svalové aktivity pacienta je vztažena k měření v uvolněném stavu získaném při kalibrační proceduře, která předchází cvičebnímu procesu. Modul vysokoúrovňového řízení nabízí několik cvičebních programů s cílem simulovat práci fyzioterapeuta. Zařízení bylo úspěšně ověřeno testováním na několika pacientech. Výsledkem bylo rozšíření rozsahu pohybu v loketním kloubu.This paper presents a novel approach to the design of a motorized rehabilitation device – active elbow orthosis (AEO) – inspired by the principles of robotic exoskeletons. The device is currently designed for the elbow joint, but can be easily modified for other joints as well. AEO determines the motion activity of the patient using a strain gauge and utilizes this measurement to control the actuator that drives the forearm part of the orthosis. Patient activity level is related to a free arm measurement obtained via a calibration procedure prior to the exercise. A high-level control module offers several types of exercises mimicking the physiotherapist. The device was successfully verified by tests on a number of patients, resulting in extended range of elbow-joint motion.

Intelligent signal processing for digital healthcare monitoring

Ein gesunder Gang ist ein komplexer Prozess und erfordert ein Gleichgewicht zwischen verschiedenen neurophysiologischen Systemen im Körper und gilt als wesentlicher Indikator für den physischen und kognitiven Gesundheitszustand einer Person. Folglich würden Anwendungen im Bereich der Bioinformatik und des Gesundheitswesens erheblich von den Informationen profitieren, die sich aus einer längeren oder ständigen Überwachung des Gangs, der Gewohnheiten und des Verhaltens von Personen unter ihren natürlichen Lebensbedingungen und bei ihren täglichen Aktivitäten mit Hilfe intelligenter Geräte ergeben. Vergleicht man Trägheitsmess- und stationäre Sensorsysteme, so bieten erstere hervorragende Möglichkeiten für Ganganalyseanwendungen und bieten mehrere Vorteile wie geringe Größe, niedriger Preis, Mobilität und sind leicht in tragbare Systeme zu integrieren. Die zweiten gelten als der Goldstandard, sind aber teuer und für Messungen im Freien ungeeignet. Diese Arbeit konzentriert sich auf die Verbesserung der Zeit und Qualität der Gangrehabilitation nach einer Operation unter Verwendung von Inertialmessgeräten, indem sie eine neuartige Metrik zur objektiven Bewertung des Fortschritts der Gangrehabilitation in realen Umgebungen liefert und die Anzahl der verwendeten Sensoren für praktische, reale Szenarien reduziert. Daher wurden die experimentellen Messungen für eine solche Analyse in einer stark kontrollierten Umgebung durchgeführt, um die Datenqualität zu gewährleisten. In dieser Arbeit wird eine neue Gangmetrik vorgestellt, die den Rehabilitationsfortschritt anhand kinematischer Gangdaten von Aktivitäten in Innen- und Außenbereichen quantifiziert und verfolgt. In dieser Arbeit wird untersucht, wie Signalverarbeitung und maschinelles Lernen formuliert und genutzt werden können, um robuste Methoden zur Bewältigung von Herausforderungen im realen Leben zu entwickeln. Es wird gezeigt, dass der vorgeschlagene Ansatz personalisiert werden kann, um den Fortschritt der Gangrehabilitation zu verfolgen. Ein weiteres Thema dieser Arbeit ist die erfolgreiche Anwendung von Methoden des maschinellen Lernens auf die Ganganalyse aufgrund der großen Datenmenge, die von den tragbaren Sensorsystemen erzeugt wird. In dieser Arbeit wird das neuartige Konzept des ``digitalen Zwillings'' vorgestellt, das die Anzahl der verwendeten Wearable-Sensoren in einem System oder im Falle eines Sensorausfalls reduziert. Die Evaluierung der vorgeschlagenen Metrik mit gesunden Teilnehmern und Patienten unter Verwendung statistischer Signalverarbeitungs- und maschineller Lernmethoden hat gezeigt, dass die Einbeziehung der extrahierten Signalmerkmale in realen Szenarien robust ist, insbesondere für das Szenario mit Rehabilitations-Gehübungen in Innenräumen. Die Methodik wurde auch in einer klinischen Studie evaluiert und lieferte eine gute Leistung bei der Überwachung des Rehabilitationsfortschritts verschiedener Patienten. In dieser Arbeit wird ein Prototyp einer mobilen Anwendung zur objektiven Bewertung des Rehabilitationsfortschritts in realen Umgebungen vorgestellt

On the structure of natural human movement

Understanding of human motor control is central to neuroscience with strong implications in the fields of medicine, robotics and evolution. It is thus surprising that the vast majority of motor control studies have focussed on human movement in the laboratory while neglecting behaviour in natural environments. We developed an experimental paradigm to quantify human behaviour in high resolution over extended periods of time in ecologically relevant environments. This allows us to discover novel insights and contradictory evidence to well-established findings obtained in controlled laboratory conditions. Using our data, we map the statistics of natural human movement and their variability between people. The variability and complexity of the data recorded in these settings required us to develop new tools to extract meaningful information in an objective, data-driven fashion. Moving from descriptive statistics to structure, we identify stable structures of movement coordination, particularly within the arm-hand area. Combining our data with numerous published findings, we argue that current hypotheses that the brain simplifies motor control problems by dimensionality reduction are too reductionist. We propose an alternative hypothesis derived from sparse coding theory, a concept which has been successfully applied to the sensory system. To investigate this idea, we develop an algorithm for unsupervised identification of sparse structures in natural movement data. Our method outperforms state-of-the-art algorithms for accuracy and data-efficiency. Applying this method to hand data reveals a dictionary of \emph{sparse eigenmotions} (SEMs) which are well preserved across multiple subjects. These are highly efficient and invariant representation of natural movement, and suggest a potential higher-order grammatical structure or ``movement language''. Our findings make a number of testable predictions about neural coding of movement in the cortex. This has direct consequences for advancing research on dextrous prosthetics and robotics, and has profound implications for our understanding of how the brain controls our body.Open Acces

Instance-based Learning with Prototype Reduction for Real-Time Proportional Myocontrol: A Randomized User Study Demonstrating Accuracy-preserving Data Reduction for Prosthetic Embedded Systems

This work presents the design, implementation and validation of learning techniques based on the kNN scheme for gesture detection in prosthetic control. To cope with high computational demands in instance-based prediction, methods of dataset reduction are evaluated considering real-time determinism to allow for the reliable integration into battery-powered portable devices. The influence of parameterization and varying proportionality schemes is analyzed, utilizing an eight-channel-sEMG armband. Besides offline cross-validation accuracy, success rates in real-time pilot experiments (online target achievement tests) are determined. Based on the assessment of specific dataset reduction techniques' adequacy for embedded control applications regarding accuracy and timing behaviour, Decision Surface Mapping (DSM) proves itself promising when applying kNN on the reduced set. A randomized, double-blind user study was conducted to evaluate the respective methods (kNN and kNN with DSM-reduction) against Ridge Regression (RR) and RR with Random Fourier Features (RR-RFF). The kNN-based methods performed significantly better (p<0.0005) than the regression techniques. Between DSM-kNN and kNN, there was no statistically significant difference (significance level 0.05). This is remarkable in consideration of only one sample per class in the reduced set, thus yielding a reduction rate of over 99% while preserving success rate. The same behaviour could be confirmed in an extended user study. With k=1, which turned out to be an excellent choice, the runtime complexity of both kNN (in every prediction step) as well as DSM-kNN (in the training phase) becomes linear concerning the number of original samples, favouring dependable wearable prosthesis applications

Instance-based learning with prototype reduction for real-time proportional myocontrol: a randomized user study demonstrating accuracy-preserving data reduction for prosthetic embedded systems

This work presents the design, implementation and validation of learning techniques based on the kNN scheme for gesture detection in prosthetic control. To cope with high computational demands in instance-based prediction, methods of dataset reduction are evaluated considering real-time determinism to allow for the reliable integration into battery-powered portable devices. The influence of parameterization and varying proportionality schemes is analyzed, utilizing an eight-channel-sEMG armband. Besides offline cross-validation accuracy, success rates in real-time pilot experiments (online target achievement tests) are determined. Based on the assessment of specific dataset reduction techniques' adequacy for embedded control applications regarding accuracy and timing behaviour, Decision Surface Mapping (DSM) proves itself promising when applying kNN on the reduced set. A randomized, double-blind user study was conducted to evaluate the respective methods (kNN and kNN with DSM-reduction) against Ridge Regression (RR) and RR with Random Fourier Features (RR-RFF). The kNN-based methods performed significantly better (p < 0.0005) than the regression techniques. Between DSM-kNN and kNN, there was no statistically significant difference (significance level 0.05). This is remarkable in consideration of only one sample per class in the reduced set, thus yielding a reduction rate of over 99% while preserving success rate. The same behaviour could be confirmed in an extended user study. With k=1, which turned out to be an excellent choice, the runtime complexity of both kNN (in every prediction step) as well as DSM-kNN (in the training phase) becomes linear concerning the number of original samples, favouring dependable wearable prosthesis applications

An investigation into the mechanisms of acute effects of dynamic stretching on ankle joint mechanics and running economy

This thesis was submitted for the award of Doctor of Philosophy and was awarded by Brunel University LondonWarm-up routines commonly include stretching to increase flexibility (joint range of motion - ROM), optimise performance, and reduce the risk of injury. Literature suggests that static stretching as part of the warm-up routines decreases force and power production compared to an active warm-up or a warm-up including dynamic stretching, and therefore could be detrimental to performance. This has led to an increased interest in the use of dynamic stretching by many athletes while the benefits of such interventions and their potential mechanisms of action are not well understood. Studies presented in this thesis were conducted to examine the effects of acute dynamic stretching on aspects of performance (e.g. torque production capacity of the plantarflexors and running economy) and to identify possible neuromechanical mechanisms underpinning any potential changes. Furthermore, we attempted to examine whether altered pain tolerance/perception to stretch may be a contributing factor to the increased ROM using adaptations in the neural substrates involved by using functional magnetic resonance imaging (fMRI) technique. In the first study, both slow dynamic stretching and fast dynamic stretching increased ROM, and this was due to an increased tendon elongation. Importantly, dynamic stretching was not detrimental to the torque producing capacity of the ankle plantarflexors. Effects of dynamic stretching on the sensorimotor performance remained mainly unclear. Employment of shear wave elastography technique in the second study suggested an increase in muscle stiffness, a decrease in fascicle strain, and showed an increase in muscle thickness after dynamic stretching, supporting an increase in tendon compliance as a contributing factor to increased flexibility after dynamic stretching. In the third study, the improved running economy by dynamic stretching may be attributable to the decreased dynamic joint ankle and vertical stiffness. The fMRI study was not conclusive due to methodological issues. Present findings have practical implications for the use of dynamic stretching in sporting contexts