6,099 research outputs found

    Fermions in odd space-time dimensions: back to basics

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    It is a well known feature of odd space-time dimensions dd that there exist two inequivalent fundamental representations AA and BB of the Dirac gamma matrices. Moreover, the parity transformation swaps the fermion fields living in AA and BB. As a consequence, a parity invariant Lagrangian can only be constructed by incorporating both the representations. Based upon these ideas and contrary to long held belief, we show that in addition to a discrete exchange symmetry for the massless case, we can also define chiral symmetry provided the Lagrangian contains fields corresponding to both the inequivalent representations. We also study the transformation properties of the corresponding chiral currents under parity and charge conjugation operations. We work explicitly in 2+1 dimensions and later show how some of these ideas generalize to an arbitrary number of odd dimensions.Comment: 8 pages, no figure

    Education for Nursing and Primary Care Providers on Nonpharmacological Management of Chronic Pain

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    Chronic pain is one of the leading causes of disability worldwide, with a significant financial burden on those individuals affected, the communities, the healthcare systems, and the government. Chronic pain also interferes with individuals’ daily activities and alters the quality of life. The treatment for chronic pain includes a variety of medications, including prescription opioids and nonprescription such as NSAIDS, acetaminophen, and muscle relaxants. Pharmacological treatments can result in untoward effects. The CDC has recommended nonpharmacological alternative treatment modalities that promote self-management but are not emphasized or utilized in the primary care setting. The staff education program was framed within the analysis, design, development, implementation, and evaluation (ADDIE) instructional design model and was presented to 10 nursing staff and providers. Evidence generated by the project included the change in knowledge from pretest to posttest. Descriptive statistics generated the pretest scores ranging from 6 to 9, with a group mean score of 7.3. Posttest scores ranged from 10 to 12, with a mean score of 11.3. A positive change in knowledge was seen with the group mean from the pretest to the posttest of +4. The participants completed the educational program’s evaluation using the dichotomous scale with met=1 and not met=2. All objectives received a “1” for a mean of 1, indicating that the program met the learning objectives. A recommendation was made to include this education for new hires and ongoing in-service education. Positive social change can be achieved using nonpharmaceutical relief measures in conjunction with prescription medications, thus improving the well-being of patients, families, and the human condition

    Rectipilus stromatoides sp. nov. (Agaricales, Basidiomycota), a new cyphelloid fungus from the Brazilian Amazon

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    [EN] A new cyphelloid species, Rectipilus stromatoides is described from the Brazilian Amazon. It is characterized by the basidiomes disposed in a pinkish stromatic structure and microscopically by the presence of cystidiols and the size of the basidiospores. The species is compared with the similar species. A key to the accepted species of Rectipilus is provided

    Longitudinal association between binge eating and metabolic syndrome in adults: findings from the ELSA-Brasil cohort.

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    Objective: Individuals with bulimia nervosa and binge eating disorder have greater cardiovascular morbidity than the general population. Longitudinal research on the association between binge eating and metabolic syndrome is limited. We tested the longitudinal association between binge eating and metabolic syndrome and its components in a large population sample of Brazilian adults. Methods: We used data from Brazilian Longitudinal Study of Adult Health (ELSA-Brasil, N = 15,105). To test for the association between binge eating at baseline (2008–2010) and metabolic syndrome at follow-up (2012–2014), we used univariable and multivariable logistic regression models progressively adjusting for potential socio-demographic confounders, number of metabolic syndrome components, and body mass index (BMI) at baseline. Results: In total, 13,388 participants (54.8% female; 52.2% white) had complete data on all variables of interest. Binge eating was associated with increased odds of metabolic syndrome at follow-up (odds ratio (OR):1.66, 95% confidence intervals (CI): 1.44, 1.75). However, the size of this association was attenuated after including number of metabolic syndrome components at baseline (OR:1.19, 95% CI: 1.05, 1.35) and was no longer present after adjusting for baseline BMI (OR:1.09, 95% CI: 0.96, 1.25). Binge eating was also associated with higher odds of hypertension (OR:1.14, 95% CI: 0.99, 1.37) and hypertriglyceridemia (OR:1.21, 95% CI: 1.06, 1.37) at the follow-up assessment after adjustment for all confounders. Conclusions: Individuals who binge eat are at increased risk of metabolic syndrome via increased BMI, and of hypertriglyceridemia and hypertension independently of BMI. If these are causal associations, effective interventions for binge eating could also have beneficial effects on metabolic health outcomes

    Elderly People With Drug-Related Problems Identified in the Emergency Department : Impact of Therapeutic Complexity on Consultations to the Health System

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    Different scales have been validated to assess the medication regimen complexity. However, the effect of this complexity on the risk of health care center consultations in patients with drug-related problems is unknown. This study's objective is to evaluate the association between the Medication Regimen Complexity Index (MCRI) and the number of drugs prescribed and new consultations to the health care system in patients who visit an emergency service due to drug-related problems. This is a retrospective observational study. We included patients >65 years who attended in an emergency service for drug-related problems. To identify variables associated with health care center reconsultation, a multivariate analysis was performed, including demographic and comorbidity variables, number of drugs prescribed, and MCRI value. Two hundred and one patients were included. A significant association was found between the prescription of more than five drugs (odds ratio [OR] = 2.50, 95% confidence interval [CI] = [1.08, 5.79]), an MCRI > 20 (2.98 [1.46-6.09]), and an increase in the number of drugs prescribed (2.87 [1.57-5.21]) and its MCRI (2.06 [1.13-3.77]) at discharge and a new visit to the emergency department. An association was found between the prescription of more than five drugs, an MCRI > 20, an increase in the number of drugs, and in MCRI value at discharge and a new visit to any other health care center. The number of prescribed drugs and the medication complexity of patients who visit the emergency department for drug-related problems was associated with an increase in the number of revisits to the emergency department and to other health care centers

    The Spanish HIV BioBank: a model of cooperative HIV research

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    <p>Abstract</p> <p>Background</p> <p>The collection of samples from HIV-infected patients is the beginning of the chain of translational research. To carry out quality research that could eventually end in a personalized treatment for HIV, it is essential to guarantee the availability, quality and traceability of samples, under a strict system of quality management.</p> <p>Methods</p> <p>The Spanish HIV BioBank was created with the objectives of processing, storing and providing distinct samples from HIV/AIDS patients, categorized according to strictly defined characteristics, free of charge to research projects. Strict compliance to ethical norms is always guaranteed.</p> <p>Results</p> <p>At the moment, the HIV BioBank possesses nearly 50,000 vials containing different prospective longitudinal study sample types. More than 1,700 of these samples are now used in 19 national and international research projects.</p> <p>Conclusion</p> <p>The HIV BioBank represents a novel approach to HIV research that might be of general interest not only for basic and clinical research teams working on HIV, but also for those groups trying to establish large networks focused on research on specific clinical problems. It also represents a model to stimulate cooperative research among large numbers of research groups working as a network on specific clinical problems. The main objective of this article is to show the structure and function of the HIV BioBank that allow it to very efficiently release samples to different research project not only in Spain but also in other countries.</p

    Psychological Capital of Spanish Workers: Confirmatory Factor Analysis of PCQ-12

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    Background: The concept of positive psychological capital draws from the study of positive organizational behavior and refers to a psychological state characterized by self-efficacy, hope, resilience, and optimism that can be developed and related to job performance. Methods: This paper analyzed the reliability and factorial structure of the Psychological Capital Questionnaire-12 (PCQ-12) in a sample composed by Spanish workers (N = 339), from different professional sectors, through a confirmatory factor analysis (CFA). Results: The analysis assessed a model with four-correlated factors competing with a second-order model proposed by the authors of this instrument. The results of the adjustment and reliability values of the dimensions are discussed in light of various studies which differ from our model or support it along with its limitations and contributes. Conclusion: Our results indicate the need to contemplate this instrument's sensitivity towards cultural differences, both geographical and organizational

    A thyroid hormone regulated asymmetric responsive centre is correlated with eye migration during flatfish metamorphosis

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    Flatfish metamorphosis is a unique post-embryonic developmental event in which thyroid hormones (THs) drive the development of symmetric pelagic larva into asymmetric benthic juveniles. One of the eyes migrates to join the other eye on the opposite side of the head. Developmental mechanisms at the basis of the acquisition of flatfish anatomical asymmetry remain an open question. Here we demonstrate that an TH responsive asymmetric centre, determined by deiodinase 2 expression, ventrally juxtaposed to the migrating eye in sole (Solea senegalensis) correlates with asymmetric cranial ossification that in turn drives eye migration. Besides skin pigmentation that is asymmetric between dorsal and ventral sides, only the most anterior head region delimited by the eyes becomes asymmetric whereas the remainder of the head and organs therein stay symmetric. Sub-ocular ossification is common to all flatfish analysed to date, so we propose that this newly discovered mechanism is universal and is associated with eye migration in all flatfish.Fundacao para a Ciencia e Tecnologia (FCT) [SFRH/BPD/66808/2009, IF/01274/2014]; FCT [SFRH/BPD/79105/2011, SFRH/BPD/89889/2012, PTDC/MAR/115005/2009, PEst-C/MAR/LA0015/2011, UID/Multi/04326/2013, Pest-OE/EQB/LA0023/2013, UID/BIM/04773/2013]; European Regional Development Fund through COMPETE; INIA; EU [RTA2013-00023-C02-01

    Assessment of Chemical Inhibitor Addition to Improve the Gas Production from Biowaste

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    The coexistence of sulphate-reducing bacteria and methanogenic archaea in the reactors during the anaerobic digestion from sulphate-containing waste could favor the accumulation of sulfide on the biogas, and therefore reduce its quality. In this study, the effect of sulphate-reducing bacteria inhibitor (MoO−2 4 ) addition in a two phase system from sulphate-containing municipal solid waste to improve the quality of the biogas has been investigated. The results showed that although SRB and sulphide production decreased, the use of inhibitor was not effective to improve the anaerobic digestion in a two phase system from sulphate-containing waste, since a significant decrease on biogas and organic matter removal were observed. Before MoO−2 4 addition the average values of volatile solid were around 12 g/kg, after 5 days of inhibitor use, those values did exceed to 28 g/kg. Molybdate caused acidification in the reactor and it was according to decrease in the pH values. In relation to microbial consortia, the effect of inhibitor was a decrease in Bacteria (44%; 60% in sulphate-reducing bacteria) and Archaea (38%) population
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