An Inverse Geometry Problem for the Localization of Skin Tumours by Thermal Analysis

In this paper, the Dual Reciprocity Method (DRM) is coupled to a Genetic Algorithm (GA) in an inverse procedure through which the size and location of a skin tumour may be obtained from temperature measurements at the skin surface. The GA is an evolutionary process which does not require the calculation of sensitivities, search directions or the definition of initial guesses. The DRM in this case requires no internal nodes. It is also shown that the DRM approximation function used is not an important factor for the problem considered here. Results are presented for tumours of different sizes and positions in relation to the skin surface

A coupled dual reciprocity BEM/Genetic algorithm for identification of blood perfusion parameters

The paper presents an inverse analysis procedure based on a coupled numerical formulation through which the coefficients describing non-linear thermal properties of blood perfusion may be identified. The numerical technique involves a combination of the Dual Reciprocity Boundary Element Method and a Genetic Algorithm for the solution of the Pennes bioheat equation. Both linear and quadratic temperature-dependent variations are considered for the blood perfusion

Solution of hyperbolic bioheat transfer problems by numerical green's functions: the ExGA-linear θ method

This paper presents a time-domain formulation called Explicit Green's approach (ExGA) linear θ method for the solution of the bioheat equation. Starting from the hyperbolic bioheat equation, which includes the parabolic one as a special case, the linear method is incorporated into the standard ExGA time marching scheme. The numerical Green's function is firstly computed in the Laplace transform domain and then back-transformed to the time domain through the Stehfest inversion algorithm. The proposed formulation has the properties of stabilizing the results and suppressing numerical oscillations that appear in the presence of discontinuous solutions as assessed through the analysis of some bioheat transfer problems.

Some operational aspects of a rotating advanced-technology space station for the year 2025

The study of an Advanced Technology Space Station which would utilize the capabilities of subsystems projected for the time frame of the years 2000 to 2025 is discussed. The study includes tradeoffs of nuclear versus solar dynamic power systems that produce power outputs of 2.5 megawatts and analyses of the dynamics of the spacecraft of which portions are rotated for artificial gravity. The design considerations for the support of a manned Mars mission from low Earth orbit are addressed. The studies extend to on-board manufacturing, internal gas composition effects, and locomotion and material transfer under artificial gravity forces. The report concludes with an assessment of technology requirements for the Advanced Technology Space Station

Numerical solution of the two-dimensional Helmholtz equation with variable coefficients by the radial integration boundary integral and integro-differential equation methods

This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2012 Taylor & Francis.This paper presents new formulations of the boundary–domain integral equation (BDIE) and the boundary–domain integro-differential equation (BDIDE) methods for the numerical solution of the two-dimensional Helmholtz equation with variable coefficients. When the material parameters are variable (with constant or variable wave number), a parametrix is adopted to reduce the Helmholtz equation to a BDIE or BDIDE. However, when material parameters are constant (with variable wave number), the standard fundamental solution for the Laplace equation is used in the formulation. The radial integration method is then employed to convert the domain integrals arising in both BDIE and BDIDE methods into equivalent boundary integrals. The resulting formulations lead to pure boundary integral and integro-differential equations with no domain integrals. Numerical examples are presented for several simple problems, for which exact solutions are available, to demonstrate the efficiency of the proposed methods

Numerical solution of the two-dimensional Helmholtz equation with variable coefficients by the radial integration boundary integral and integro-differential equation methods

This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2012 Taylor & Francis.This paper presents new formulations of the boundary–domain integral equation (BDIE) and the boundary–domain integro-differential equation (BDIDE) methods for the numerical solution of the two-dimensional Helmholtz equation with variable coefficients. When the material parameters are variable (with constant or variable wave number), a parametrix is adopted to reduce the Helmholtz equation to a BDIE or BDIDE. However, when material parameters are constant (with variable wave number), the standard fundamental solution for the Laplace equation is used in the formulation. The radial integration method is then employed to convert the domain integrals arising in both BDIE and BDIDE methods into equivalent boundary integrals. The resulting formulations lead to pure boundary integral and integro-differential equations with no domain integrals. Numerical examples are presented for several simple problems, for which exact solutions are available, to demonstrate the efficiency of the proposed methods

Photometric Variability and Astrometric Stability of the Radio Continuum Nucleus in the Seyfert Galaxy NGC 5548

The NRAO VLA and VLBA were used from 1988 November to 1998 June to monitor the radio continuum counterpart to the optical broad line region (BLR) in the Seyfert galaxy NGC 5548. Photometric and astrometric observations were obtained at 21 epochs. The radio nucleus appeared resolved, so comparisons were limited to observations spanning 10-60 days and 3-4 yr, and acquired at matched resolutions of 1210 mas = 640 pc (9 VLA observations), 500 mas = 260 pc (9 VLA observations), or 2.3 mas = 1.2 pc (3 VLBA observations). The nucleus is photometrically variable at 8.4 GHz by $33\pm5$% and $52\pm5$% between VLA observations separated by 41 days and 4.1 yr, respectively. The 41-day changes are milder ($19\pm5$%) at 4.9 GHz and exhibit an inverted spectrum ($\alpha \sim +0.3\pm0.1$, $S\propto \nu ^{+\alpha}$) from 4.9 to 8.4 GHz. The nucleus is astrometrically stable at 8.4 GHz, to an accuracy of 28 mas = 15 pc between VLA observations separated by 4.1 yr and to an accuracy of 1.8 mas = 0.95 pc between VLBA observations separated by 3.1 yr. Such photometric variability and astrometric stability is consistent with a black hole being the ultimate energy source for the BLR, but is problematic for star cluster models that treat the BLR as a compact supernova remnant and, for NGC 5548, require a new supernova event every 1.7 yr within an effective radius $r_e =$ 42 mas = 22 pc. A deep image at 8.4 GHz with resolution 660 mas = 350 pc was obtained by adding data from quiescent VLA observations. This image shows faint bipolar lobes straddling the radio nucleus and spanning 12 arcsec = 6.4 kpc. These synchrotron-emitting lobes could be driven by twin jets or a bipolar wind from the Seyfert 1 nucleus.Comment: with 9 figures, to appear in the Astrophysical Journal, 2000 March 10, volume 53

CO2 Targets, Trajectories and Trends for International Shipping

The Shipping in Changing Climates (SCC) project connects the latest climate change science with knowledge, understanding and models of the shipping sector in a whole systems approach. It seeks to explore the potential to cut CO2 through the use of technical and operational changes in shipping and to understand how the sector might transition to a more resilient and low-carbon future; it also seeks to explore different climate change scenarios and related food and fuel security issues to gain an understanding of the direct and indirect impacts of climate change on the shipping sector. These scenarios can be used to build evidence and understanding around the range of potential future directions that the shipping industry may take. The RCUK Energy funded project brings together researchers from UCL (Energy Institute, Mechanical Engineering and Laws), Manchester, Southampton, Newcastle and Strathclyde, in close collaboration with a core industry stakeholder group of Shell, Lloyd’s Register, Rolls Royce, BMT and Maritime Strategies International, but drawing on the expertise and connections of over 35 companies and organisations worldwide. This paper is non-peer- reviewed and represents the collective opinions of the authors and should not be assumed to represent the views of all the researchers across the project or the project’s industry partners and their organisations

CCN activation experiments with adipic acid: effect of particle phase and adipic acid coatings on soluble and insoluble particles

Slightly soluble atmospherically relevant organic compounds may influence particle CCN activity and therefore cloud formation. Adipic acid is a frequently employed surrogate for such slightly soluble organic materials. The 11 published experimental studies on the CCN activity of adipic acid particles are not consistent with each other nor do they, in most cases, agree with the Köhler theory. The CCN activity of adipic acid aerosol particles was studied over a significantly wider range of conditions than in any previous single study. The work spans the conditions of the previous studies and also provides alternate methods for producing "wet" (deliquesced solution droplets) and dry adipic acid particles without the need to produce them by atomization of aqueous solutions. The experiments suggest that the scatter in the previously published CCN measurements is most likely due to the difficulty of producing uncontaminated adipic acid particles by atomization of solutions and possibly also due to uncertainties in the calibration of the instruments. The CCN activation of the small (<i>d</i><sub><i>m</i></sub><150 nm) initially dry particles is subject to a deliquescence barrier, while for the larger particles the activation follows the Köhler curve. Wet adipic acid particles follow the Köhler curve over the full range of particle diameters studied. In addition, the effect of adipic acid coatings on the CCN activity of both soluble and insoluble particles has also been studied. When a water-soluble core is coated by adipic acid, the CCN-hindering effect of particle phase is eliminated. An adipic acid coating on hydrophobic soot yields a CCN active particle. If the soot particle is relatively small (<i>d</i><sub>core</sub>≤102 nm), the CCN activity of the coated particles approaches the deliquescence line of adipic acid, suggesting that the total size of the particle determines CCN activation and the soot core acts as a scaffold