350 research outputs found

    Guía del médico práctico o Resumen general de patología interna y de terapéutica aplicadas

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    Encuadernados juntos t.I-t.II, t.III-t.IV, t.V-VI y t.VII-VIII13 v.;19 cm.Contiene: t.I - t.II - t.III - t.IV - t. V - t. VI - t.VII - t.VIIIEjemplar donado por A. Linares Maza (Biblioteca de Medicina)CCPB00023532

    Current use of peat, plastic and fertiliser inputs in organic horticultural and arable crops across Europe

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    The use of contentious inputs linked to plant protection, and the use of peat, plastic and fertilisers used in growing have been mapped in selected organically produced crops in 10 countries across Europe. This report refers the output of this mapping. It shows that organic production has not come very far to phase out peat or plastic. The consumption of these materials seems to be quite comparable to non-organic production systems.The main utilisation of peat is for production of young plants (transplants). Most organic growers purchase plants e.g. for citrus, olives and grafted tomatoes and the growing media has usually a high content of peat. Vegetable transplants are also commonly produced by special growers. Peat is also used for casing layers for organic mushrooms, and as a potting media for aromatic plants. For plastic, the use is extensive for mulching and to protect crops against frost, less often for insect protection. The use of plastic materials to attach young plants to sticks etc., and to protect grafting wounds in young trees, was also observed. While not big in volume, this use may contribute to micro-plastic waste. Plastic is also very common for solarisation and for tunnels and greenhouses, especially in southern countries. In northern countries,greenhouses are usually made of other materials than plastic. Further research within the Organic PLUS project will reveal farmers and growers who have worked with promising alternatives and develop these further. For applied fertilisers, which in our context need to be approved for use in certified organic production, the application of commercial products seems to be higher in some countries, e.g. Greece, whereas other countries seem to use much less. This may be explained by economic conditions of the growers, cultural differences, by the extent of organic production and development of a market for such products, by the availability of national fertiliser Companies and by other factors. Information about raw materials used to produce these fertilisers is commonly not readily available but may sometimes be found under information about the company’s history. These website sections also reveal that fusions of fertiliser Companies occur rapidly. Many fertiliser products seem to be derived from residuals from sugar or starch production. Horn grid, meat and bone meal, blood meal and feather meals are well known organic fertilisers but were not so much observed in this study. Instead, we observed that animal hides are an important raw material for organic N fertilisers. Seaweed products are quite common, whereas fish-based products were only mentioned from UK. Non-organic manure (from conventional farms) is used in all countries, commonly as pelletised dry poultry manure

    Organic farming and climate change: major conclusions of the Clermont-Ferrand seminar (2008)

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    This seminar confirmed that less greenhouse gas (GHG) is emitted per unit area under organic agriculture than under conventional agriculture, and that our eating patterns have a strong impact on factors involved in climate change. Moreover, it shed new light on and contributed original information to a variety of fields. The two major advantages of organic farming in terms of the mitigation of GHG emissions are its ability to store carbon in the ground and the non-use of synthetic nitrogen fertilisers. Means for improving practices and research priorities were identified

    Peat, plastic and fertiliser in organic growing across Europe - current use and future options

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    The use of cntentious inputs in organic growing was mapped across Europe in the H2020 Project "Organic-PLUS" (GA 774340) during 2018. This paper presents results on peat, plastic and animal-derived fertilisers in horticultural growing. Broadly, the use of peat and plastic is similar to non-organic production. Many organic growers use transplants, and the growing media usually contain peat. For plastic, the use is widespread for mulching and frost protection. Plastic is also used as tree guards and attaching clips. As a fertilisation input, dried poultry manure is used in all countries. Many more commerical fertilisers are in use. They are often made from animal hide or vinasse. The application of such products varies widely between countries. The project aims to develop alternatives to these contentious inputs, which will be presented

    Definition of the Gene Content of the Human Genome: The Need for Deep Experimental Verification

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    Based on the analysis of the drafts of the human genome sequence, it is being speculated that our species may possess an unexpectedly low number of genes. The quality of the drafts, the impossibility of accurate gene prediction and the lack of sufficient transcript sequence data, however, render such speculations very premature. The complexity of human gene structure requires additional and extensive experimental verification of transcripts that may result in major revisions of these early estimates of the number of human genes

    ?2-Microglobulin Amyloid Fibril-Induced Membrane Disruption Is Enhanced by Endosomal Lipids and Acidic pH

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    Although the molecular mechanisms underlying the pathology of amyloidoses are not well understood, the interaction between amyloid proteins and cell membranes is thought to play a role in several amyloid diseases. Amyloid fibrils of ?2-microglobulin (?2m), associated with dialysis-related amyloidosis (DRA), have been shown to cause disruption of anionic lipid bilayers in vitro. However, the effect of lipid composition and the chemical environment in which ?2m-lipid interactions occur have not been investigated previously. Here we examine membrane damage resulting from the interaction of ?2m monomers and fibrils with lipid bilayers. Using dye release, tryptophan fluorescence quenching and fluorescence confocal microscopy assays we investigate the effect of anionic lipid composition and pH on the susceptibility of liposomes to fibril-induced membrane damage. We show that ?2m fibril-induced membrane disruption is modulated by anionic lipid composition and is enhanced by acidic pH. Most strikingly, the greatest degree of membrane disruption is observed for liposomes containing bis(monoacylglycero)phosphate (BMP) at acidic pH, conditions likely to reflect those encountered in the endocytic pathway. The results suggest that the interaction between ?2m fibrils and membranes of endosomal origin may play a role in the molecular mechanism of ?2m amyloid-associated osteoarticular tissue destruction in DRA
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