A study of Neospora caninum antibody seroprevalence ın dairy cows in Turkey

ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗNeospora caninum is a intracellular protozoan parasite and is one of the major causes of repeated abortions, foetal malformations, pre-term deliveries, stillbirth and possible loss of milk yield in livestock. The presence of specific antibodies against N. caninum in the blood serum of dairy cows is investigated in the present study. A total of 184 blood serum samples of dairy cows were examined in Bursa province in the Marmara Region. N. caninum antibodies were measured using an indirect enzyme-linked immunosorbent assay (ELISA) (The Svanovir Neospora-Ab ELISA). From the total sample, antibodies to N. caninum were detected in 62 of the 184 examined cows (33.3%) and neurological findings were seen in a calf

A multi-perspective analysis of social context and personal factors in office settings for the design of an effective mobile notification system

In this study, we investigate the effects of social context, personal and mobile phone usage on the inference of work engagement/challenge levels of knowledge workers and their responsiveness to well-being related notifications. Our results show that mobile application usage is associated to the responsiveness and work engagement/challenge levels of knowledge workers. We also developed multi-level (within- and between-subjects) models for the inference of attentional states and engagement/challenge levels with mobile application usage indicators as inputs, such as the number of applications used prior to notifications, the number of switches between applications, and application category usage. The results of our analysis show that the following features are effective for the inference of attentional states and engagement/challenge levels: the number of switches between mobile applications in the last 45 minutes and the duration of application usage in the last 5 minutes before users' response to ESM messages

Deep learning for detection and segmentation of artefact and disease instances in gastrointestinal endoscopy

The Endoscopy Computer Vision Challenge (EndoCV) is a crowd-sourcing initiative to address eminent problems in developing reliable computer aided detection and diagnosis endoscopy systems and suggest a pathway for clinical translation of technologies. Whilst endoscopy is a widely used diagnostic and treatment tool for hollow-organs, there are several core challenges often faced by endoscopists, mainly: 1) presence of multi-class artefacts that hinder their visual interpretation, and 2) difficulty in identifying subtle precancerous precursors and cancer abnormalities. Artefacts often affect the robustness of deep learning methods applied to the gastrointestinal tract organs as they can be confused with tissue of interest. EndoCV2020 challenges are designed to address research questions in these remits. In this paper, we present a summary of methods developed by the top 17 teams and provide an objective comparison of state-of-the-art methods and methods designed by the participants for two sub-challenges: i) artefact detection and segmentation (EAD2020), and ii) disease detection and segmentation (EDD2020). Multi-center, multi-organ, multi-class, and multi-modal clinical endoscopy datasets were compiled for both EAD2020 and EDD2020 sub-challenges. The out-of-sample generalization ability of detection algorithms was also evaluated. Whilst most teams focused on accuracy improvements, only a few methods hold credibility for clinical usability. The best performing teams provided solutions to tackle class imbalance, and variabilities in size, origin, modality and occurrences by exploring data augmentation, data fusion, and optimal class thresholding techniques

Structural changes to resorbable calcium phosphate bioceramic aged <i>in vitro</i>

This work investigates the effect of mammalian cell culture conditions on 3D printed calcium phosphate scaffolds. The purpose of the studies presented was to characterise the changes in scaffold properties in physiologically relevant conditions. Differences in crystal morphologies were observed between foetal bovine serum-supplemented media and their unsupplemented analogues, but not for supplemented media containing tenocytes. Scaffold porosity was found to increase for all conditions studied, except for tenocyte-seeded scaffolds. The presence of tenocytes on the scaffold surface inhibited any increase in scaffold porosity in the presence of extracellular matrix secreted by the tenocytes. For acellular conditions the presence or absence of sera proteins strongly affected the rate of dissolution and the distribution of pore diameters within the scaffold. Exposure to high sera protein concentrations led to the development of significant numbers of sub-micron pores, which was otherwise not observed. The implication of these results for cell culture research employing calcium phosphate scaffolds is discussed

Measurement of the νe−\nu_e-Nucleus Charged-Current Double-Differential Cross Section at <Eν>=\left< E_{\nu} \right> = 2.4 GeV using NOvA

The inclusive electron neutrino charged-current cross section is measured in the NOvA near detector using $8.02\times10^{20}$ protons-on-target (POT) in the NuMI beam. The sample of GeV electron neutrino interactions is the largest analyzed to date and is limited by $\simeq$ 17\% systematic rather than the $\simeq$ 7.4\% statistical uncertainties. The double-differential cross section in final-state electron energy and angle is presented for the first time, together with the single-differential dependence on $Q^{2}$ (squared four-momentum transfer) and energy, in the range 1 GeV $\leq E_{\nu} <$6 GeV. Detailed comparisons are made to the predictions of the GENIE, GiBUU, NEUT, and NuWro neutrino event generators. The data do not strongly favor a model over the others consistently across all three cross sections measured, though some models have especially good or poor agreement in the single differential cross section vs. $Q^{2}$

Petrochemical and 40Ar/39Ar geochronogical evidence of postcollisional Tertiary calc-alkaline volcanism in the Ulubey (Ordu), eastern Pontide, NE Turkey

Post-collisional Tertiary volcanism in the Ulubey region at the western edge of the eastern Pontides paleo-arc started with sediments in a shallow marine environment in the Paleocene-Eocene time and then continued extensively with sub-aerial andesitic and rare basaltic volcanism during Eocene and Miocene time. The volcanic rocks studied are mainl yandesite/trachyandesite and rarely basalt/trachybasalt andpyroclastics, and show porphyric, hyalo-microlitic porphyricand rarely glomeroporphyric, intersertal, intergranular, fluidal and sieve textures. The volcanic rocks indicate a magma evolution fromtholeiitic-alkaline transitional to calc-alkaline, and have medium to high-K in character. Petrochemical data of the rocks suggest a dominant fractional crystallization and less crustal contamination processes in their evolution. Most samples have also low Mg#, Cr, and Ni, which indicates that they have undergone significant fractional crystallization from mantle-derived melts. Generally, major and trace element geochemical variations in the rocks can be explained by fractionation of common mineral phases. E-MORB normalized trace element patterns show that Ulubey volcanic rocks have geochemical patterns with enrichment in LILE and to a lesser extent in LREE, but depletion in HFSE. The volcanic rocks have moderate LREE/HREE ratios relative to E-Type MORB, depletion in Nb, Ta and Ti, and high Th/Yb ratios indicate that these patterns probably reflect magma derived from an enriched source formed by mixing of slab and asthenospheric melts previously modified by fluids and sediments from a subduction zone. The chondrite-normalized REE patterns of these volcanics resemble to each other and spoon-shaped with low to medium enrichment, indicating similar source area for the basaltic and andesitic rocks. The most primitive samples have YbN<10, which indicates the presence of garnet as a residual phase in the mantle source. The 40Ar-39Ar dating of the basaltic rocks 15.1±0.6 Ma and the andesitic rocks are between 44.6±0.1 and 49.4±0.1 Ma. The rocks evolved from a parental magma derived from an enriched source formed by subduction induced metasomatism of basaltic rocks formed clinopyroxene ± titanomagnetite controlled fractionation whereas andesitic rocks developed hornblende + plagioclase + clinopyroxene ± titanomagnetite controlled fractionation and, rare crustal contaminaion in shallow level magma chamber(s)

Clinical, ultrasonography and haematology of aglepristone-induced mid-gestation pregnancy terminations in rabbits

Aglepristone is a safe abortifacient in cats, dogs and rabbits. Although no serious side effects have been reported, there is no information available about the effects of the medicine on haematological parameters. For the first time clinical and ultrasonographic features and haematological profiles were evaluated in rabbits treated with aglepristone 15 and 16 days after mating. Ten healthy 10–14 month-old New Zealand White female rabbits were mated with fertile bucks and pregnancies were confirmed by ultrasound 15 days later. Of these, 5 does were treated with aglepristone (test group, n = 5) whilst the remaining five (control group, n = 5) were treated with a saline solution (0.9% NaCl). The treatment dose was 10 mg⁄kg body weight, administered subcutaneously once daily on two consecutive days (day 15 and 16 post mating). Ultrasonographic, clinical and haematological assessments were performed daily. Aglepristone treatment induced embryonic fluid resorptions without foetal death in mid-gestation terminations. Following ultrasonographic and haematological examinations, it was established that aglepristone is a safe abortifacient in rabbits