Evaluation of patients with fibrotic interstitial lung disease: Preliminary results from the Turk-UIP study

OBJECTIVE: Differential diagnosis of idiopathic pulmonary fibrosis (IPF) is important among fibrotic interstitial lung diseases (ILD). This study aimed to evaluate the rate of IPF in patients with fibrotic ILD and to determine the clinical-laboratory features of patients with and without IPF that would provide the differential diagnosis of IPF. MATERIAL AND METHODS: The study included the patients with the usual interstitial pneumonia (UIP) pattern or possible UIP pattern on thorax high-resolution computed tomography, and/or UIP pattern, probable UIP or possible UIP pattern at lung biopsy according to the 2011 ATS/ERSARS/ALAT guidelines. Demographics and clinical and radiological data of the patients were recorded. All data recorded by researchers was evaluated by radiology and the clinical decision board. RESULTS: A total of 336 patients (253 men, 83 women, age 65.8 +/- 9.0 years) were evaluated. Of the patients with sufficient data for diag-nosis (n=300), the diagnosis was IPF in 121 (40.3%), unclassified idiopathic interstitial pneumonia in 50 (16.7%), combined pulmonary fibrosis and emphysema (CPFE) in 40 (13.3%), and lung involvement of connective tissue disease (CTD) in 16 (5.3%). When 29 patients with definite IPF features were added to the patients with CPFE, the total number of IPF patients reached 150 (50%). Rate of male sex (p<0.001), smoking history (p<0.001), and the presence of clubbing (p=0.001) were significantly high in patients with IPE None of the women <50 years and none of the men <50 years of age without a smoking history were diagnosed with IPE Presence of at least 1 of the symptoms suggestive of CTD, erythrocyte sedimentation rate (ESR), and antinuclear antibody (FANA) positivity rates were significantly higher in the non-IPF group (p<0.001, p=0.029, p=0.009, respectively). CONCLUSION: The rate of IPF among patients with fibrotic ILD was 50%. In the differential diagnosis of IPF, sex, smoking habits, and the presence of clubbing are important. The presence of symptoms related to CTD, ESR elevation, and EANA positivity reduce the likelihood of IPF

Cihangir Mosque

Tez (Yüksek Lisans) -- İstanbul Teknik Üniversitesi, Fen Bilimleri Enstitüsü, 2015Thesis (M.Sc.) -- İstanbul Technical University, Institute of Science and Technology, 2015Araştırma konusu olan Cihangir Camisi, Kanuni Sultan Süleyman tarafından, Haseki Hürrem Sultan’dan olan küçük şehzadesi Cihangir için 1559 – 1560 yıllarında Mimar Sinan’a yaptırılmıştır. Cami birçok kez yangın geçirdikten sonra 1889 – 1893 yıllarında Sultan II. Abdülhamit zamanında ise son kez, büyük ihtimal ile mimar Sarkis Balyan’a yaptırılarak günümüze ulaşmıştır. Caminin gerek ilk yapım dönemi olan 16. yüzyılda ve gerekse son yapım dönemleri olan 19. yüzyıldaki yapılarında değişmez plan şeması olarak dörtgen mekân üzerine kubbe ve yanlarda minare tasarımı kullanılmıştır. Geçirdiği bu dönemlerde, devrinin üslubuna göre biçimlenmiş olan cami son yapımıyla da Osmanlı İmparatorluğu’nun batılılaşma dönemindeki örneklerinden birini oluşturmuştur. Cami son olarak yapıldığı dönemde de, klasik Osmanlı mimari karakterini kaybetmemiş ve plan şemasındaki klasik tasarımın hâkimiyeti korunmuştur. Caminin ilk yapılışından bu yana geçirdiği yangınlar, doğal afet ve zamanın da doğal sonucu oluşan yıpranma ve kayıpları olmuştur. Son olarak 19. yüzyılda ikinci kez yeniden yapım süreçleri üzerinde yapılan araştırmalar ve çalışmalardan gözlemlenen sonuç, orijinali Mimar Sinan tarafından yapılan dörtgen planlı, tek kubbeli, önce tek daha sonra çift minareli olarak yaptırılan caminin ana karakteri ve plan tasarımında değişiklik olmadığıdır. Fakat camiye bağlı diğer bölümlerin (Tekke, hazire, hücre odacıklar, imarethane, sıbyan mektebi, avlu, sarnıç) mimari özellikleri ve yerleşim düzenleri hakkında kesin bilgiler olmadığından aynı kanıya varmak mümkün olamamaktadır. Caminin sade, gösterişten uzak süslemeleri ve tasarım sadeliğine karşın, 19. yy. daki batılılaşma etkileri cephe süslemelerinde dönemin bir karakteristiği olarak barok, rokoko, neoklasik, ampir süslemeler ile kendini göstermiştir. İç mekânda aydınlatma unsuru olarak avize, kandil kullanılmış seccadelerle ve duvarları dönemin tanınmış hattatlarının isimlerini içeren, Kur’an’dan ayetlerin yazılı olduğu levhalar ve sade kalem işleriyle süslenmiştir. Osmanlı İmparatorluğu’nun batılılaşma hareketinin getirdiği değişikliklerden, mimarlık alanındaki yapıtların da etkilendiği görülmektedir. Camimiz de bu değişiklikler süslemelerde ve özellikle yelpaze görünümünde açılan pencere düzenlemeleriyle açıkça görülmektedir. Bu bağlamda Cihangir Camisi, Sultan II. Abdülhamit zamanında son olarak yeniden yapılmasına rağmen klasik Osmanlı cami planından sapma göstermemiş ancak Dönem!in üslubunu yansıtan tasarım ve süsleme özellikleri ile birlikte Batı Mimarlığı izlerini de barındıran bir yapı haline gelmiştir.In this study we have examined and review the Mosque of Cihangir, during the years of 1559– 2015 which has been built under the reign of Süleyman the Magnificent for his son Cihangir; Who was also the son of Hürrem Sultan. Mosque was constructed in beetween 1559 and 1560 by Master Architect Mimar Sinan. The Mosque endured many fires but it has reached it’s latest outlook under the reign of Sultan Abdülhamit II, who has (strongly probable ) had the architect by Sarkis Balyan restore it between during the years1889 and 1893. We see that, during the building of the mosque, both in the 16. century and secondly in the 19. century, the unchanged plan of quatriladeral floor – base covered by one dome and minarets. Mosque remains one of the examples of classical Ottoman architecture. The original complex included other parts which not exists today.The design is the culmination of two centuries. With traditional Islamic Architecture and is one of the first mosque of the Classical period and secondly Westernization period.İnside decorations include verses from the Qur’an, many of them made by regarded as the greatest calligrapher of his time. The floors are covered with carpets, which are donated by the faithfull people and they are regularly replaced as they wear out. The many spacious windows confer a spacious impression glass windows with their intricate designs with Baroque elements and admit natural light. The many lamps inside the mosque were once covered with gold and gems. The great tablets on the walls are inscribed with the names of the caliphs and verses from the Quran. Considering all the periods that the mosque has seen, it should have been shaped according to those periods. However it can be seen that it has remained as the one of the last examples of the Westernisation period of the Ottoman Empire. Even during the last restoration it can be seen that it hasn’t lost it’s classical characterictics of Ottoman Architecture. it can be clearly seen that in it’s plan sheme; the rule of the classical theme.Ever since the Mosque’s first consruction; İt has endured many fires and a earthquake. Mosque’s final restoration was in the 19. century, it can be seen that it has kept it’s original scheme of plan from the Grand Architect Sinan ‘s period. We can cleary see Westernization influences and applications in the Mosque as being a masterpiece. However, it can’t be clearly understood the architectural specialities of the other portions of the Mosque. If the Mosque’s basic decorations and architecture are taken in to consideration, İt can be seen that during the 19 centuries in Westernization period the Baraque and rococo style decorations seen as the period characteristic of decorative style.If it can be judged , the aim of the Westernisation motives of the Ottoman period was not to change the cultural and artistic infrastructure but it was to fit in and to avoid the downfall of the Empire. Our subject the mosque of Cihangir encompasses all the characteristics of the time periods it has existed in .However it hasn’t shown any change from the classical Ottoman mosque plan sheme. But it can also be said that it has brought about certain architectural characrteristics according to Westernisation period.As a result it can be said that the mosques classical architecture can be redefined within the revaluation of the classical period. During Byzantine times, the area of the present neighborhood was probably not settled, although there were Byzantine buildings near present day Tophane and Fındıklı along the Bosphorus below Cihangir.During the reign of Süleiman the magnificent , the area was a forested hunting ground, it was one of the favorite places of Süleiman’s son Cihangir and after Cihangir’s death, Suleiman had mimar Sinan build a probably a wooden mosque there overlooking the Bosphorus. The neighborhood’s name comes from this mosque.Cihangir is one of the neigborhoods of the Beyoğlu district in İstanbul, the neighborhood has many narrow streets and it is located between Beyoğlu and Kabataş. The name means ’Conquerer’’ in Turkish and in turn, comes from the Persian compound word Johan+gir, meaning ‘’conqueror’’ of the world. The Cihangir mosque from which the neighborhood got it’s name, is like a prototype of the Dolmabahçe Mosque. Cihangir Mosque built by Mimar Sinan under the orders of Kanuni Sultan Süleyman, ( Suleiman the Magnificent) the original mosque, had quite a dramatic story, Suleiman, armed with the motive that his son Şehzade Mustafa ckoked to death. As a result, Hürrem’s son Şehzade Cihangir dies of grief and the mosque is constructed in his memory. İn late 19.th century, Levantines used to live in Cihangir, just like in Pera, In the 1920s and 1930s, Cihangir only consisted of two districts, In the 1940s and 50s the people that were working at entertainment spots in Beyoğlu began to live in Cihangir. This led to the construction of new buildings and the district became a settlement for well endowed people . After the second half of the 90s with the support of the public bodies and the efforts of the non-govermental organization the district gained it’s recent identity.The lexical meaning of the word ‘’Cihangir’’ is The person that captured the major part of the world ‘’ however, it is weird that such an ambitious word is the name for this mild district. To find out the fact we need to go back to the past to Suleyman the Magnificent had a son from Hürrem Sultan, named Cihangir. For the memory of his son, who died young. Suleiman had a mosque constructed in this place that looked like a large rock protruding from the sea The mosque that was constructed by mimar Sinan between the years 1559-1560 and was name Şehzade Cihangir Mosque this is how the district began to be called Cihangir. One of the places where you can see an amazing landscape of İstanbul.Cihangir Mosque’s garden has the best view of Bosphorus and İstanbul during the reign of Suleiman the Magnificent. The Cihangir district took it’s name from this mosque that sits high up on hill and overlooks the Bosphorus and is one of Mimar Sinan’s designs. İt was built in the 16th. century to commemorate Süleiman the magnificent son, Cihangir who in 1553 died of grief after his half brother Mustafa had been murdered by order of their father.Today building was reconstructed by Abdülhamit II in 1874 after the original building burnt down and althought it resembles the work of the famous architects the ‘’ Balyan Family’’they were not responsible fort his one. The mihrab inside has clouds painted on it that gives an impression of a stage set in a theatre. The picturesque Cihangir Mosque stands at the beginning points Cihangir Avenue. who died in Aleppo at the age of 22. When the mosque was totally damaged during the big fire in the 19.century. It was rebuilt by conntractor (foreman) Yani Kalfa and Todori Kalfa ( at he minaret ) and architect is unknown but strongly probably ( Sarkis Balyan ) with the order of Abdülhamit II. The Cihangir Mosque has one dome, two minarets and vaulted beautiful windows and interiorly decorated with distinctive examples of the line art . Baroque styled Cihangir Mosque looks similar to Dolmabahçe and Ortaköy Mosque.Yüksek LisansM.Sc

Cyclical Behavior of Stock Exchange Index By Sectors: A Case From Turkey

In this study, the relation between the cyclical behaviors of stock market indices of industry, service, finance and technology sectors at Istanbul Stock Exchange and gross domestic product of Turkey between the 1998 January and 2011 September, is analyzed. The results suggest that stock exchange indices move in the same direction with economic activity and stock market leads the economy by about one quarter. However, when the sectoral differences are considered, movements in technology sector index are transmitted to economy in two months whereas it is three months for the industrial and service sector. The slowest sector is the financial sector for which pass-through speed is four months. (C) 2012 Published by Elsevier Ltd. Selection and/or peer review under responsibility of Prof. Dr. Huseyin ArasliWo

DES MAITRISES.

Transcript of DES MAITRISES by Joseph d'Ortigue, appearing in LE MÉNESTREL, 5 juillet 1857, pp. 1–3

An Investigation of cyber wellness awareness: Turkey secondary school students, teachers, and parents

Mıhçı Türker, Pınar ( Aksaray, Yazar )Cyber wellness includes the knowledge, skills, and values geared toward the protection of Internet users as well as proper and responsible technology use. Using the survey method, this study investigated the cyber wellness awareness of secondary school students and teachers as well as parents’ perceptions of their children’s cyber wellness. Six thousand eight hundred thirty-nine (6,839) students, 749 teachers, and 4,916 parents participated. Cyber wellness survey forms for students, teachers, and parents were distributed to seven school districts. Results indicated that students had high levels of awareness with regard to Internet addiction, cyberbullying, online privacy, and cybersecurity and medium levels of awareness regarding netiquette, inappropriate online content, and copyright. Additionally, students’ awareness levels differed significantly in terms of gender, class level, Internet use span, and desire for education on safe and responsible Internet use. Teachers had medium levels of awareness with respect to all of the concepts. Furthermore, it was determined that parents considered that their children had medium levels of awareness regarding Internet addiction, netiquette, online privacy, inappropriate online content, copyright, and cybersecurity along with a high level of awareness regarding cyberbullying

A Case of Hypopharyngeal Cancer Associated With Fanconi Anemia: A Helical Tomotherapy Experience

Fanconi anemia (FA) is a disease that could be accompanied by multiple abnormalities, such as growth retardation, bone marrow abnormalities, and cancer susceptibility. Among the FA patients, head and neck squamous cell cancer (HNSCC) is the most observed solid cancer. The life expectancy of patients with FA has increased with recent medical advances. Furthermore, HNSCC is diagnosed in 3% of FA patients, and half of these patients die because of their HNSCC. The median age of HNSCC patients with FA is 31, and according to the literature HNSCC incidence of FA, patients is more than 700-fold of the normal population. Here, we reported the treatment details and challenges we faced during hypopharyngeal cancer treatment in a FA patient

The views of elementary mathematics education preservice teachers on proving

This study has been prepared with the purpose to get the views of senior class Elementary Education Mathematics preservice teachers on proving. Data have been obtained via surveys and interviews carried out with 104 preservice teachers. According to the findings, although preservice teachers have positive views about using proving in mathematics teaching, it is seen that their experiences related to proving is limited to courses and they think proving is a work done only for the exams. Furthermore, they have expressed in the interviews that proving is difficult for them, and because of this reason they prefer memorizing instead of learning