2,528 research outputs found

    A Comparative Analysis of Airline Pilots’ Approaches to Learning

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    This paper reports a study investigating approaches to learning (deep, surface, achieving) by airline pilots. Three hundred and forty-six respondents from five international airlines and an institute completed the Pilot Learning Process Questionnaire (PLPQ). The results showed a general tendency for surface scores to be substantially lower than deep and achieving scores, with greatest variability among the carriers on the achieving scale. The European carrier was implicated in all post hoc analyses conducted and one Pacific Rim carrier\u27s profile showed significant differences from other airlines. The results are discussed in terms of cultural, training/rewards, and tenure factors. Implications for pilot training and selection are noted

    Which anthropometric and lower body power variables are predictive of professional and amateur playing status in male rugby union players?

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    The purpose of this study was to compare anthropometric and lower body power measurements between current professional and amateur male rugby union players. The present study also sought to determine which anthropometric and physical performance variables were predictive of playing standard. Thirty professional and 30 amateur RU players performed Wattbike 6 s maximal effort (WB6S) and countermovement (CMJ) and squat jump (SJ) assessments, anthropometric measures were also taken. Dependant variables recorded and analysed including: body mass, stature, Σ8 site skinfolds, WB6S absolute and relative peak power, CMJ and SJ average concentric force, jump height, peak velocity, time to peak force, rate of force development (RFD) and absolute and relative peak force and power. Professional players were heavier, taller and leaner than their amateur counterparts (p < 0.05). Professional players performed significantly better in all physical performance measures except CMJ and SJ time to peak force, CMJ RFD and SJ relative peak force. Variables which were predictive of playing standard were: Σ8 skinfolds, CMJ peak velocity and WB6S absolute and relative peak power (p < 0.05). These findings indicate that the current body of male professional RU players is anthropometrically and physically superior to their amateur counterparts, although not all variables assessed here were predictive of playing standard. Data presented here indicate that Σ8 skinfolds, WB6S absolute and relative power and CMJ peak velocity are predictive of playing standard, whereas other anthropometric and strength and power variables are not

    Perceptions of Trust: Communicating Climate Change to Cattle Producers

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    The Cattle and Climate Conversations Workshop for Cooperative Extension and Natural Resources Conservation Service, the last activity funded through a multi-regional United States Department of Agriculture’s National Institute of Food and Agriculture (USDA NIFA) grant, took place in October 2016 in Denver, Colorado, for Extension and Natural Resources Conservation Service (NRCS) representatives in the Southwest and Mountain West who work extensively with cattle producers. The purpose of this study was to identify how Extension agents and NRCS personnel in this workshop viewed the issue of “trust,” as it relates to communicating the topic of climate change to cattle producers. Three focus groups, comprised of 29 attendees of the workshop, were conducted simultaneously at the end of the conference. Specific themes about trust included the politically charged nature of climate change, climate change data manipulation, negativity of media surrounding climate change, weathercasters getting predictions wrong, agriculture getting a “black eye” with the public, and participants’ relationships with cattle producers. Findings indicate varying levels of distrust, related to sources of information and influence on the topic of climate change, greatly impact how and whether Extension Service and NRCS employees actually talk “climate change” to cattle producers. Based on the study’s findings, it is recommended that for Extension and NRCS employees to talk about controversial issues, like climate change, it is important to create relationships with clients. In addition, communication and education professionals working with cattle producers should avoid politicizing the topic of climate change if they want climate-related programs to be accepted

    The Roth Project - Music and Memory: A Community Agency Initiated Individualized Music Intervention for People with Dementia

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    Introduction “The Roth Project - Music and Memory” is a music based intervention program, implemented by the Alzheimer’s Association of Central and Western Kansas, which provides a nonpharmacologicalmeans for addressing neuropsychiatric symptoms in individuals with dementia. Methods Participants were individuals with dementia who were enrolled in The Roth Project - Music and Memory. Post-intervention surveys were distributed to caregivers of participants which assessed caregiver satisfaction with the program as well as caregiver perception of the impact of individualized music on mood and behavioralsymptoms. Results Of returned surveys (n = 79), 99% of caregivers indicated they were satisfied or very satisfied with the program and 94% of caregivers perceived participants to like or very much like listening to the music. While a substantial number of participants required assistance with iPod use (95%), the majority of participants were observed to listen to the music with stable or increased frequency over time. Personalized music was observed to improve mood in 78% of cases, with the most frequent benefits being improved overall happiness, decreased anxiety, increased positive emotional expression, and decreased depression. Conclusions The Roth Project - Music and Memory was well received by caregivers and was perceived to benefit mood of individuals with dementia. These results provided ongoing support for individualized music-based interventions and demonstrated that such interventions, when implemented by community agencies, can be well received by those who use them

    What is the role of culture, diversity, and community engagement in transdisciplinary translational science?

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    Concepts of culture and diversity are necessary considerations in the scientific application of theory generation and developmental processes of preventive interventions; yet, culture and/or diversity are often overlooked until later stages (e.g., adaptation [T3] and dissemination [T4]) of the translational science process. Here, we present a conceptual framework focused on the seamless incorporation of culture and diversity throughout the various stages of the translational science process (T1-T5). Informed by a community-engaged research approach, this framework guides integration of cultural and diversity considerations at each phase with emphasis on the importance and value of "citizen scientists" being research partners to promote ecological validity. The integrated partnership covers the first phase of intervention development through final phases that ultimately facilitate more global, universal translation of changes in attitudes, norms, and systems. Our comprehensive model for incorporating culture and diversity into translational research provides a basis for further discussion and translational science development

    Comparative Immunogenicity of HIV-1 Clade C Envelope Proteins for Prime/Boost Studies

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    BACKGROUND: Previous clinical efficacy trials failed to support the continued development of recombinant gp120 (rgp120) as a candidate HIV vaccine. However, the recent RV144 HIV vaccine trial in Thailand showed that a prime/boost immunization strategy involving priming with canarypox vCP1521 followed by boosting with rgp120 could provide significant, although modest, protection from HIV infection. Based on these results, there is renewed interest in the development of rgp120 based antigens for follow up vaccine trials, where this immunization approach can be applied to other cohorts at high risk for HIV infection. Of particular interest are cohorts in Africa, India, and China that are infected with clade C viruses. METHODOLOGY/PRINCIPAL FINDINGS: A panel of 10 clade C rgp120 envelope proteins was expressed in 293 cells, purified by immunoaffinity chromatography, and used to immunize guinea pigs. The resulting sera were collected and analyzed in checkerboard experiments for rgp120 binding, V3 peptide binding, and CD4 blocking activity. Virus neutralization studies were carried out with two different assays and two different panels of clade C viruses. A high degree of cross reactivity against clade C and clade B viruses and viral proteins was observed. Most, but not all of the immunogens tested elicited antibodies that neutralized tier 1 clade B viruses, and some sera neutralized multiple clade C viruses. Immunization with rgp120 from the CN97001 strain of HIV appeared to elicit higher cross neutralizing antibody titers than the other antigens tested. CONCLUSIONS/SIGNIFICANCE: While all of the clade C antigens tested were immunogenic, some were more effective than others in eliciting virus neutralizing antibodies. Neutralization titers did not correlate with rgp120 binding, V3 peptide binding, or CD4 blocking activity. CN97001 rgp120 elicited the highest level of neutralizing antibodies, and should be considered for further HIV vaccine development studies

    Confirmation of a New Metal-poor Globular Cluster in the Galactic Bulge

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    © 2018. The American Astronomical Society. All rights reserved.We use deep near-IR photometry of the VISTA Variables in the V'a L'ctea (VVV) Survey and deep DECam Plane Survey (DECaPS) optical photometry to confirm the physical reality of the candidate globular cluster (GC) Minni 22, which is located in the Galactic bulge. This object, which was detected as a high density region in our maps of bulge red giants, is now confirmed as a real GC based on the optical and near-IR color'magnitude diagrams. We also recover three known fundamental mode (ab type) RR Lyrae stars within 2 arcmin of the cluster center. The presence of RR Lyrae stars also seems to confirm Minni 22 as a bonafide old and metal-poor GC. We estimate a cluster reddening E(J - Ks) = 0.6 mag and determine its heliocentric distance D = 7.4 ± 0.3 kpc. The optical and near-IR color'magnitude diagrams reveal well-defined red giant branches in all cases, including a red giant branch bump at Ks = 13.30 ± 0.05 mag. The comparison with theoretical isochrones yields a mean metallicity of [Fe/H] = -1.3 ± 0.3 dex, and age of t ∼ 11.2 Gyr. This is a good example of a new low-luminosity (MV = -6.2 mag) GC found in the central bulge of the Milky Way. After discussing the different ways to confirm the existence of bulge GC candidates, we find that one of the best methods is to use the CMDs from the combination of the DECaPS + VVV photometries.Peer reviewe

    Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes

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    Type 2 diabetes is associated with insulin resistance, impaired pancreatic β-cell insulin secretion, and nonalcoholic fatty liver disease. Tissue-specific SWELL1 ablation impairs insulin signaling in adipose, skeletal muscle, and endothelium, and impairs β-cell insulin secretion and glycemic control. Here, we show that

    Resource utilization and outcome at a university versus a community teaching hospital in tPA treated stroke patients: a retrospective cohort study

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    <p>Abstract</p> <p>Background</p> <p>Comparing patterns of resource utilization between hospitals is often complicated by biases in community and patient populations. Stroke patients treated with tissue plasminogen activator (tPA) provide a particularly homogenous population for comparison because of strict eligibility criteria for treatment. We tested whether resource utilization would be similar in this homogenous population between two hospitals located in a single Midwestern US community by comparing use of diagnostic testing and associated outcomes following treatment with t-PA.</p> <p>Methods</p> <p>Medical records from 206 consecutive intravenous t-PA-treated stroke patients from two teaching hospitals (one university, one community-based) were reviewed. Patient demographics, clinical characteristics and outcome were analyzed, as were the frequency of use of CT, MRI, MRA, echocardiography, angiography, and EEG.</p> <p>Results</p> <p>Seventy-nine and 127 stroke patients received t-PA at the university and community hospitals, respectively. The two patient populations were demographically similar. There were no differences in stroke severity. All outcomes were similar at both hospitals. Utilization of CT scans, and non-invasive carotid and cardiac imaging studies were similar at both hospitals; however, brain MR, TEE, and catheter angiography were used more frequently at the university hospital. EEG was obtained more often at the community hospital.</p> <p>Conclusions</p> <p>Utilization of advanced brain imaging and invasive diagnostic testing was greater at the university hospital, but was not associated with improved clinical outcomes. This could not be explained on the basis of stroke severity or patient characteristics. This variation of practice suggests substantial opportunities exist to reduce costs and improve efficiency of diagnostic resource use as well as reduce patient exposure to risk from diagnostic procedures.</p
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