6 research outputs found
Tracer studies in the solution chemistry of heavy elements
- Author
- Publication venue
- Publication date
- 01/01/1965
- Field of study
Sorption of yttrium, lanthanum and cerium (III) ions on Zeo-Karb 225 (SRC 15) and De-acidite from perchlorate media has been studied at 25 C and a tracer concentration of the ions concerned. It has been found that the sorption of these ions on the resins in question follows nearly an identical pattern, and that the changes of the hydrogen-ion concentration in the pH range of 2.5-4 have only a very slight effect on the values of the distribution co-efficients. Taking yttrium-glycollate as a representative for the systems involving glycollate or other ligands and the triva-lent rare-earth ions and those from the actinium series using yttrium-91 as a tracer and a perchlorate medium of μ = 0.50M, the effect of the cross-linking of a resin on the β(_n) values of the system in question has been studied and found to be negligible for the 2%, 4-5%, and 8% DVB resins provided the necessary corrections due to swelling of the resins are duly taken into account. An investigation of the same system with Zem-Karb 225 (SRC 15) at different v/m ratios in the range of 15/0.20 and 15/0.60 has revealed that subject to the appropriate corrections due to swelling of the resin having been made, such changes of the v/m ratio have no significant effect on the values of the system concerned. It has been further observed that a treatment of a complexing solution with resins of different cross-linking practically entails no significant loss of the ligand species (glycollate) from the complexing solution. Having made the above investigations of the resin/solution behaviour in perchlorate media at 25 C, the method (cation-exchange) was adopted for a tracer study of the systems involving yttrium, lanthanum, cerium (III),europium (III), actinium and americium (III) ions and chloride, fluoride, sulphate, oxalate, -hydroxyisobutyrate and glycollate ligands. The stability constants have been computed by a graphic method based on a theory proposed by Fronaeus (^78,102). The results obtained are generalize in good agreement with those reported by other workers as a result of their investigation of the systems in question by ion-exchange, solvent-extraction, pH or potentiometric methods under comparable conditions, and have further shown the dependence of the chemistry of the concerned ions on the sizes of their respective crystal ionic-radii. The ratios of the β(_I) values for the lanthanum/ actinium and europium (III)/americium (III) systems involving sulphate, oxalate and α-hydroxyisobutyrate ligands have been worked out and found to be in general near unity; this is an evidence in support of similar interactions between the metal ions of both the lanthanum and actinium series and the noted ligands in aqueous systems
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
- Abadia M
- Abassy J
- Abate E
- Abbott Tom EF
- Abdelaal Samir A
- Abdeldayem H
- Abdelkabir M
- Abdelsamed A
- Abdulwahed E
- Abiyere H
- Abou Chaar MK
- Abukhalaf SA
- Abukhalaf Sadi
- Adamina Michel
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Adeyeye A
- Adisa Adewale
- Afzal MF
- Agarwal Arnav
- Aggarwal M
- Agnes A
- Agostini C
- Agrawal A
- Agrawal N
- Agresta F
- Aguiar Junior S
- Ahmed A
- Ahmed K
- Ahmed Nafees R
- Ahmed Z
- Ahn JH
- Aime A
- Akhtar N
- Akkulak Murat
- Akrivou D
- Al Abdallah M
- Al Riyami S
- Al Sayed M
- Al-Masri M
- Al-Najjar H
- Al-Slaibi I
- Alaa S
- Alakaloko Felix
- Alameer Ehab
- Alamri Alex
- Alawneh F
- Albertsmeier M
- Albertsmeier Markus
- Alderson Derek
- Aldokali N
- Alemanno G
- Alfieri S
- Algallai M
- Ali AA
- Alkadiki Ghadah Z
- Almaadany Faraj S
- Almeida AC
- Almeida-Reis R
- Almezghwi H
- Almond Max
- Alrahawy M
- Alser Osaid
- Alshaar Muhammad
- Alshareea E
- Alshareef K
- Alshryda Sattar
- Alsoufi A
- Altamirano Riquoir C
- Altomare DF
- Altomi I
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- Alvarez MR
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- Alzeerelhouseini IAH
- Amaral MJ
- Amira G
- Amorim E
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- Wullschleger M
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- Zourntou S
- Publication venue
- 'Royal College of Obstetricians & Gynaecologists (RCOG)'
- Publication date
- 01/06/2022
- Field of study
AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
Adaptation of the Wound Healing Questionnaire universal-reporter outcome measure for use in global surgery trials (TALON-1 study): mixed-methods study and Rasch analysis
- Author
- Abantanga Francis Atindaana
- Abayomi Olukayode
- Abayomi Olukayode
- Abdulai Darling Ramatu
- Abdulai Ramatu Darling
- Abdullahi Lawal
- Abdullahi Lawal Barau LB
- Abdulsalam Moruf
- Abdur-Rahman Lukman
- Abdur-Rahman Lukman Olajide
- Abdus-Salam Rukiyat
- Abdus-Salam Rukiyat A
- Abubakari Fatao
- Abunimye Esther
- Acevedo Diego Luna
- Acheampong Dorcas Otuo
- Acheampong Dorcas Otuo
- Acquah Ato Oppong
- Acquah Ato Oppong
- Acquah Daniel Kwesi
- Acquah Daniel Kwesi
- Acquah Regina
- Acquah Regina
- Acquaye Jane
- Acquaye Jane
- Adagrah Luke Aniakwo
- Adam-Zakariah Leslie Issa
- Adam-Zakariah Leslie Issa
- Adams Mary Augusta
- Adams Mary Augusta
- Addo Kwame Gyambibi
- Adebayo Francis
- Adebayo Francis O
- Adebayo Sikiru
- Adebayo Sikiru Adekola
- Adebunmi Adeoluwa
- Adedotun Adesiyakan
- Adeleke Akeem
- Adeleke Nurudeen
- Adeleke Nurudeen Abiola
- Adeleye Victoria
- Adeleye Victoria
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji O
- Ademuyiwa Adesoji O
- Ademuyiwa Adesoji O
- Adenikinju Wilson
- Adeniran Abimbola
- Adeniyi Olumide
- Adeniyi Oluwafunmilayo
- Adeniyi Oluwafunmilayo
- Adepiti Akinfolarin
- Aderounmu Adewale
- Aderounmu Adewale A
- Adesanya Opeoluwa
- Adesola Muideen
- Adesunkanmi Abdulhafiz
- Adewunmi Abdus-sami
- Adinku Michael
- Adinku Michael
- Adisa Adewale
- Adisa Adewale O
- Adisa Adewale O
- Adjei Faisal
- Adjei-Acquah Esther
- Adjei-Acquah Esther
- Ado Khadija
- Ado Khadija A
- Adobea Vivian
- Adobea Vivian
- Adu-Aryee Nii Armah
- Adu-Aryee Nii Armah
- Adu-Brobbey Raphael
- Adu-Brobbey Raphael
- Afolabi Rafiat
- Afolabi Rafiat Tinuola
- Agbedinu Kwabena
- Agbeko Anita Eseenam
- Agbeko Anita Eseenam
- Agboadoh Nelson
- Agboton Gerard
- Aggarwal Manisha
- Agodirin Sulaiman
- Aguirre Celina Cuellar
- Aguirre Laura Reyes
- Aguirre Laura Reyes
- Agyekum Vera
- Agyekum Vera
- Agyemang Eric
- Agyemang Eric
- Ahmed Hafsa Imtiyaz
- Ahossi Rene
- Aisuodionoe-Shadrach Oseremen
- Aisuodionoe-Shadrach Oseremen
- Ajai Olalekan
- Ajai Olalekan T
- Ajao Akinlabi
- Ajao Akinlabi E
- Ajekwu Samuel
- Ajenjfuja Olusegun
- Akaba Godwin
- Akaba Godwin O
- Akande Olukemi
- Akesseh Rebecca Adjeibah
- Akinajo Opeyemi
- Akinajo Opeyemi
- Akinboyewa David
- Akinboyewa David
- Akindojutimi Jerrie
- Akinkuolie Akinbolaji
- Akosa Enoch Appiah
- Akoto Erica
- Akpla Marcelin
- Alakaloko Felix
- Alakaloko Felix
- Alasi Iyabo
- Alasi Iyabo
- Alatise Olusegun
- Alexander Philip
- Alexander Philip V
- Alhassan Bin Baaba Alhaji
- Alhassan Shamudeen Mohammed
- Aliyu Salele Mohammed AS
- Aliyu Mohammed
- Allen Olubukola
- Ally Zain
- Ally Zain
- Alpheus Rahul
- Amankwa Emmanuel Gyimah
- Amao Olayide Michael
- Ameh Lazarus
- Ameh Lazarus
- Ameh Lazarus
- Ametefe Elikem
- Amoah George
- Amoah Michael
- Amoah Michael
- Amoako James
- Amoako James
- Amoako Joachim Kwaku
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- Amoako-Boateng Mabel Pokuah
- Amosu Lukmon
- Amponsah-Manu Forster
- Amponsah-Manu Forster
- Amusat Olanrewaju
- Anachy Jeremiah P
- angeles Bueno Wenceslao G
- Ankomah James
- Ankomah James
- Anyanwu Lofty-John
- Anyawu Lofty-John Chukwuemeka LJC
- Appiah Akosua Dwamena
- Appiah Akosua Dwamena
- Appiah Anthony Baffour
- Appiah Anthony Baffour
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- Appiah Juliana
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- Arellano Ana Bogurin
- Aremu Isiaka
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- Armah Ralph
- Arowolo Olukayode
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- Arthur Joshua
- Aruldas Neerav D
- Asabre Esther
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- Asare Christopher
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- Assouto Pamphile
- Atobatele Kazeem
- Atoyebi Oluwole
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- Attepor Godsway Solomon
- Avendano Alejandro Cuevas
- Awonuga David
- Ayandipo Omobolaji
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- Ayantona Deborah
- Ayim Alex
- Ayinde Ademola
- Ayingayure Emmanuel
- Ayingayure Emmanuel
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- Baltazar Gomez Isaac
- Banka Charles
- Barbosa Camacho Francisco J
- Barimah Charles Gyamfi
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- Boateng Ruby Acheampong
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- Brown Julia
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- Bueno Wenceslao Angeles
- Bunogerane Gisele Juru
- Camacho Francisco Barbosa
- Cerdan Claudia Caballero
- Cervantes Ortiz Reyes J
- Cervantes Reyes Ortiz
- Chakrabortee Sohini
- Chakrabortee Sohini
- Chakrabortee Sohini
- Chiejina Godwin
- Chiejina Godwin O
- Chobli Hugues Herve
- Choudhrie Ashish
- Chowdri Nisar A
- Christian Kyeremeh
- Cook Jonathan
- Coompson Christian Larbi
- Coompson Christian Larbi
- Cortes Flores Ana O
- Cortes Torres Edgar J
- Cousens Simon
- Crawford Richard
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- Cuevas Avendano Alejandro
- Dadzie Samuel
- Dadzie Samuel
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- Dally Charles
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- Daniel Swati
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- Dankwah Fred
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- Davor Anthony
- Davor Anthony
- de Dieu Haragirimana Jean
- de Dieu Haragirimana Jean
- de la Fuente Alejandra Nayen Sainz
- de la Fuente Alejandra Nayen Sainz
- de la Medina Antonio Ramos
- de la Medina Antonio Ramos
- de la Medina Antonio Ramos
- de la Medina Antonio Ramos
- de la Medina Antonio Ramos
- de la Medina Antonio Ramos
- de la Medina Antonio Ramos
- de Rojas Erick Gonzalez Garcia
- Debrah Samuel A
- Debrah Samuel A
- del Campo Laura Urdapilleta Gomez
- Dhamija Parth
- Dhar Tapasya
- Dhiman Jyoti
- Dhiman Jyoti
- Doe Stanley
- Dokponou Mireille
- Dominguez Sansores Luis A
- Dominguez Solano David R
- Doris Emily
- Dossou Francis Moise
- Dossou Francis Moise
- Dossou Francis Moise
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- Duran Irani
- Duru Nnamdi Jonathan
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- Dusabe Moses
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- Dutta Rohini
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- Ede Chikwendu Jeffrey
- Ede Jude
- Ede Jude K
- Edet Ekpo
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- Edwin Yenli
- Egbuchulem Kelvin
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- Egwuonwu Ochomma Amobi
- Eke Grace
- Ekenze Sebastian
- Ekenze Sebastian O
- Ekwesianya Andrew
- Ekwuazi Hyginus
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- Ekwunife Okechukwu
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- Elebute Olumide
- Elebute Olumide
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- Elemile Peter
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- Emmanuel Owusu Abem
- Enemuo Vincent
- Enemuo Vincent C
- Enoch Akosa Appiah
- Enti Donald
- Enti Donald
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- Ezenwankwo Francis
- Ezinne Uba
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- Ezomike Uchechukwu O
- Faboya Omolara
- Faboya Omolara M
- Fasiku Olushola
- Fatuga Adedeji
- Fenu Benjamin
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- Flores Oscar Olvera
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- Fosu Godfred
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- Fourtounas Maria
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- Gakpetor Delali Akosua
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- Galley Fareeda
- Gallo Mariana Barreto
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- Gaou Antoine
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- Gawu Victoria Sena
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- Ghosh Dhruva
- Ghosh Dhruva
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- Ghosh Dhruva
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- Glasbey James
- Glasbey James
- Glasbey James
- Godwin Serbeh
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- Gonzalez Ojeda Alejandro
- Gonzalez Gonzalo Hernandez
- Goudou Roland
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- Goyal Sunita
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- Gyamfi Brian
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- Gyamfi Frank Enoch
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- Valadez Michel Hernandez
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- Vazquez Diana S Gonzalez
- Vazquez Diana Samantha Gonzalez
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- Zechariah Pradeep
- Zechariah Pradeep
- Zirikana Job
- Zirikana Job
- Zounon Mack-Arthur
- Zume Marshall
- Zume Marshall
- Publication venue
- Oxford University Press (OUP)
- Publication date
- 01/01/2023
- Field of study
BackgroundThe Bluebelle Wound Healing Questionnaire (WHQ) is a universal-reporter outcome measure developed in the UK for remote detection of surgical-site infection after abdominal surgery. This study aimed to explore cross-cultural equivalence, acceptability, and content validity of the WHQ for use across low- and middle-income countries, and to make recommendations for its adaptation.MethodsThis was a mixed-methods study within a trial (SWAT) embedded in an international randomized trial, conducted according to best practice guidelines, and co-produced with community and patient partners (TALON-1). Structured interviews and focus groups were used to gather data regarding cross-cultural, cross-contextual equivalence of the individual items and scale, and conduct a translatability assessment. Translation was completed into five languages in accordance with Mapi recommendations. Next, data from a prospective cohort (SWAT) were interpreted using Rasch analysis to explore scaling and measurement properties of the WHQ. Finally, qualitative and quantitative data were triangulated using a modified, exploratory, instrumental design model.ResultsIn the qualitative phase, 10 structured interviews and six focus groups took place with a total of 47 investigators across six countries. Themes related to comprehension, response mapping, retrieval, and judgement were identified with rich cross-cultural insights. In the quantitative phase, an exploratory Rasch model was fitted to data from 537 patients (369 excluding extremes). Owing to the number of extreme (floor) values, the overall level of power was low. The single WHQ scale satisfied tests of unidimensionality, indicating validity of the ordinal total WHQ score. There was significant overall model misfit of five items (5, 9, 14, 15, 16) and local dependency in 11 item pairs. The person separation index was estimated as 0.48 suggesting weak discrimination between classes, whereas Cronbach's α was high at 0.86. Triangulation of qualitative data with the Rasch analysis supported recommendations for cross-cultural adaptation of the WHQ items 1 (redness), 3 (clear fluid), 7 (deep wound opening), 10 (pain), 11 (fever), 15 (antibiotics), 16 (debridement), 18 (drainage), and 19 (reoperation). Changes to three item response categories (1, not at all; 2, a little; 3, a lot) were adopted for symptom items 1 to 10, and two categories (0, no; 1, yes) for item 11 (fever).ConclusionThis study made recommendations for cross-cultural adaptation of the WHQ for use in global surgical research and practice, using co-produced mixed-methods data from three continents. Translations are now available for implementation into remote wound assessment pathways
SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study
- Author
- Aamir Junaid
- Abaalkhail Muath
- Ababneh Adnan
- Ababneh Hazim
- Ababneh Laila
- Ababneh Roba
- Abad-Motos Ane
- Abaker Mussab
- Abary Ryan
- Abass Adam
- Abate Emmanuele
- Abayomi Olukayode
- Abazeed Alaa
- Abbad Bader
- Abbadessa Francesco
- Abbadi Osaid
- Abbakar Malaz
- Abbas Ahmed
- Abbas Alzhraa
- Abbas Asad
- Abbas Aya
- Abbas Jihad
- Abbas Manzar
- Abbas Mohammad
- Abbas Omer
- Abbasov Aykhan
- Abbo Olivier
- Abbott Daniel
- Abbott Tom
- Abboud Omar
- Abd Waleed
- Abd-Elkariem Ahmed
- Abd-Elsalam Sherief
- Abdalah Ahmad
- Abdalhadi Alya
- Abdalla Ahmed
- Abdalla Eman
- Abdalla Samir
- Abdalla Shimaa
- Abdalla Siddig
- Abdallah Emne
- Abdallah Ghaida
- Abdallah Lubna
- Abdallah Munir
- Abdallah Murad Al
- Abdallah Rasha
- Abdalnour Hani
- Abdeen Bashar
- Abdeewi Saedah
- Abdeh Louai
- Abdel-Aleem Mahmoud
- Abdel-Elsalam Wafaa
- Abdel-Fattah Areej
- Abdel-Fattah Nour
- Abdel-Hafez Ibrahim
- Abdelaal Abdelrahman
- Abdelaty Ahmed Adel
- Abdelazeem Khaled
- Abdelaziz Areej
- Abdelaziz Mohammed
- Abdelbagi Mohamad
- Abdelbaset Abouelnour
- Abdeldayem Hesham
- Abdelfattah Mahmoud
- Abdelgadir Alwaleed
- Abdelgalel Khaled
- Abdelghafar Moslem
- Abdelhafez Mohammed
- Abdeljalil Abdelkarim
- Abdelkabir Mohammed
- Abdelkareem Mohamed
- Abdelkarem Mohamed
- Abdelkarim Mostafa
- Abdelkhalek Mohamed
- Abdellah Fatima
- Abdelmajeed Ahmed
- Abdelmalik Abubaker
- Abdelmawla Ahmed
- Abdelrahman Abdelrahman
- Abdelrahman Haneen
- Abdelraouf Ali
- Abdelsamed Ahmed
- Abdelwahab Omar
- Abderrazaq Hafni
- Abdissa Desalegn
- Abdo Adnan Sayid
- Abdou Hossam
- Abdou Mostafa
- Abdoun Meriem
- Abdow Mohammad
- Abdrabou Ahmed
- Abdualqader Mahmmoud
- Abdul-Jabar Hani
- Abdul-Mumin Alhassan
- Abdulaal Safaa
- Abdulateef Omar
- Abdulfattah Ammar Yasser
- Abdulkareem Amal
- Abdull Mohammed
- Abdullaev Abakar
- Abdullah Abdullah
- Abdullah Bahiyah
- Abdullah Duha Milad
- Abdullah Muhammad Tariq
- Abdullah Nabila
- Abdullah Saleha
- Abdullah Shahbaz
- Abdullaha Lamess
- Abdullahi Alhassan
- Abdullahi Habiba
- Abdullahi Lawal
- Abdullahi Mohammed Kabir
- Abdullahi Sani
- Abdullahi Yasir Younis
- Abdulmalek Abdulmalek
- Abdulmalik Abdulmuez
- Abdulmohsen Ahmed
- Abdulqawi Nabil
- Abdulrahem Abdullah
- Abdulrahman Mamuda
- Abdulrahman Mohamed
- Abdulrahman Taha
- Abdulsalam Albaraa
- Abdulsalam Fareed
- Abdulsalam Khalifa
- Abdulsalam Moruf
- Abdulwahab Taiceer
- Abdulwahed Eman
- Abdunabi Murad
- Abdur-Rahman Lukman
- Abdurab Ebrahim
- Abdurehman Oumer
- Abdurrazzaaq Abdussemee
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abe Anthonia
- Abe Nobutsugu
- Abe Tatsuro
- Abebe Engida
- Abebe Kirubel
- Abebe Metasebia
- Abebe Nebyou
- Abebrese John Tabiri
- Abed Arsan Abu
- Abed Francisco
- Abed Haneen
- Abed Laith Abu
- Abedalqader Lina
- Abedin Yasmin
- Abel Joel Reuben
- Abel Livingston
- Abel Mary Kathryn
- Abelevich Alexander
- Abella Andrei Cesar
- Abichou Wijden
- Abid Rubaba
- Abiodun Adekunle
- Abiola Olajide
- Abiola Paul
- Abiyere Henry
- Aboalsamh Ghaleb
- Aboazamazem Hajir
- Abodeeb Aya
- Aboelkhel Roger
- Abojeila Farah
- Abosamak Nour Eldin
- Abosnaina Yahya
- Abostate Ahmed
- Abou-Abbass Hussein
- Abou-Khalil Jad
- Abouassi Layth
- Abouassi Majd
- Aboubakr Samar
- Aboubeirah Mohammed
- Abouelazayem Mohamed
- Abouelnagah Galal
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- Aboutaleb Shereen
- Aboutrab Ayham
- Abouzid Amr
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- Abrate Alberto
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- Abu-Ishkerih Nizar
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- Abu-Zaid Ahmed
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- Abubakar Abdullah
- Abubakar Ahmed
- Abubakar Mohammed Kabir
- Abubakr Abubakr
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- Abubeih Hossam
- Abud Burçin
- Abudari Hadeel
- Abudher Abdulhafid
- Abuhamour Ehab
- Abuissa Khatab
- Abukhadra Mahmoud
- Abukhalaf Sadi A
- Abukhater Muhammad
- Abulafia Daniel
- Abuleil Amro
- Abulshuwashi Nayrouz Abdullah
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- Abusabeib Abdelrahman
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- Abusalem Marwa
- Abusannoga Malek
- Abushahma Ahmed Omar
- Abutaka Ahmad
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- Acatrinei Eduard
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- Ackermann Travis
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- Adam John
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- Afolabi Abdulrahman O
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- Lucas Miriam Abellan
- Maadany Faraj Al
- Mahdawi Leyla Al
- Mahdy Hossam Al
- Makari Reem Al
- Manji Adil Al-Karim
- Maqtari Siham Al
- Mariño Mauricio Agüero
- Martinez Yicel Alvarez
- Maryam A
- Matas Fernando Alcaide
- Mendoza Veronica Alonso
- Mensah Kwasi Agyen
- Mintah Dominic Annor
- Moagal Rehab Al
- Moawad Karim Abdelraouf
- Mohamed Mohamed Ali
- Mohsen Mustafa Abo
- Momani Tareg Al
- Muhfouz Dima Abu
- Muhtadi Fadhl Al
- Mulke Rahaf Al
- Murgueitio Natalia Cortes
- Mutani Mohammed Al
- Nafesa Aminah Al
- Nahian Syed Al
- Najjar Majed Al
- Najjar Tasneem Al
- Nami Awaji Al
- Nassar Saleh Al
- Nepogodiev Dmitri
- Neto Alfeu Accorsi
- Noval Patricia Corriols
- Nwijy Khaled Ai
- Obead Hamza Abu
- Oliver Renato Aguera
- Omair Shehanah Al
- Otaibi Faisal Al
- Picciochi Maria
- Pinto João Almeida
- Polo Miriam Abdulkarim
- Qadhi Hani Al
- Qudhaya Rashed Al
- Qureshi Talha Ahmed
- Rahim Norazila
- Rahman Noorneza Abdul
- Rahman Norhafiza
- Raisi Amani Al
- Rashed Asmaa Al
- Rego Juliana Almeida
- Riaz Shujat Ahmed
- Riobello Eva Andreu
- Riyami Nihal Al
- Riyami Salim Al
- Ros Conrado Andrés
- Roselló Irene Vives
- Rubio Eva Corral
- Rueda Ignacio Alcalá
- Saad Sarah Ahmed
- Sabti Hilal Al
- Saez Iago Alvarez
- Saied Ghiath Al
- Salam Omar Abdul
- Salama Ibrahim Abdelkader
- Sanany Ghadeer Al
- Santos Daniel Costa
- Sayed Mohamed Al
- Sebastian Isabel Alonso
- Shaalah Ahmed Abdullah
- Shaibi Maha Al
- Shaikh Shafqat Ali
- Shanab Ahmed Abo
- Sharie Ahmed Al
- Shukri Asmaa Al
- Simoes Joana
- Smadi Omar Al
- Soares Rui Costa
- Soucheiron Maria Coronas
- Subaie Saud Al
- Suyyagh Kais Al
- Tarieh Ammar Abu
- Torres Eva Alvarez
- Victoria Czarlo Dela
- Villamayor Verónica Alen
- Vinayagam Raman
- Vincenti Cara
- Vincenzi Matteo
- Vinz Franziska
- Violante Tommaso
- Violas Philippe
- Violette Mukanyange
- Viotti Fabio
- Virdi Amrita
- Virgilio Edoardo
- Virgincar Ashwini
- Virta Ville P
- Viscido German
- Vishnoi Jeewan Ram
- Vishwakarma Sunil Kumar
- Vishwani Vartika
- Vissapragada Ravi
- Viste Claire
- Viswanath Yks
- Vitowanu Julius
- Viveiros Octavio
- Viveros-Carreño David
- Vives Inmaculada
- Vives-Barquiel Marian
- Vivian-Taylor Josephine
- Vix Michel
- Vlad Ioan Catalin
- Vlad Schitcu
- Vladimir Novgorodskii
- Vleminckx Nils
- Vo Uyen Giao
- Vogel Jon
- Vogel Keianna
- Vogel Rachel
- Vogelsang Holger
- Vogler Thomas
- Vogt Kelly
- Vohra Ravinder
- Vokshi Ismail
- Volkova Olga
- Volpe Gustavo Jardim
- Volpin Enrico
- Volpin Francesco
- von Ehrlich-Treuenstätt Viktor H
- von Renesse Janusz
- von Rundstedt Friedrich-Carl
- Voonna Murali Krishna
- Voppuru Saiesh Reddy
- Vora Sameer
- Voros Peter
- Vosoughi Fardis
- Vossler Kristen
- Vounckx Manon
- Vourganti Srinivas
- Vovola Fernanda
- Vozian Marin
- Vrakopoulou Gavriella Zoi
- Vömel Jacob
- Wadei Hajr Al
- Yahya Zakaria Al
- Zahran Mohammed
- Zahrani Attiya Al
- Zahrani Turki Ai
- Zaid Muna
- Zein Zeina Al
- Álvarez Sofia
- Älgå Andreas
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2021
- Field of study
Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.
Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV estimates were stratified by age (18-49, 50-69, 70 or more years) and type of surgery. Best- and worst-case scenarios were used to describe uncertainty.
Results: NNVs were more favourable in surgical patients than the general population. The most favourable NNVs were in patients aged 70 years or more needing cancer surgery (351; best case 196, worst case 816) or non-cancer surgery (733; best case 407, worst case 1664). Both exceeded the NNV in the general population (1840; best case 1196, worst case 3066). NNVs for surgical patients remained favourable at a range of SARS-CoV-2 incidence rates in sensitivity analysis modelling. Globally, prioritizing preoperative vaccination of patients needing elective surgery ahead of the general population could prevent an additional 58 687 (best case 115 007, worst case 20 177) COVID-19-related deaths in 1 year.
Conclusion: As global roll out of SARS-CoV-2 vaccination proceeds, patients needing elective surgery should be prioritized ahead of the general population
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
- Author
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- Abadia M
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- Abad‐Motos A
- Abassy J
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- García Alonso M
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- García Septiem J
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- Gegúndez Simón A
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- Gennari S
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- George G
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- Geroukalis A
- Ghaly G
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- Ghosh Dhruva
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- Giacometti M
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- Glasbey James C
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- Glass N
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- Golda T
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- González Argente FX
- González de Miguel M
- González‐Nicolás Trébol MT
- Goodrum S
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- Green L
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- Griffiths Ewen A
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- Grossi U
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- Grove T
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- Gujjuri Rohan R
- Gultekin FA
- Gundara J
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- Gupta A
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- Gutelkin Murat
- Gutierrez Samaniego M
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- Guven O
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- Gómez Díaz CJ
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- Gönüllü E
- Güler SA
- Güreşin A
- Hacım NA
- Hagger R
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- Haji A
- Hakami I
- Halkias C
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- Hall J
- Hamdan KH
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- Hammed S
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- Hamza HM
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- Handa S
- Hanly A
- Hanna M
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- Harald M
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- Hardie CM
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- Harries R
- Harris Benjamin
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- Harris G
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- Hart C
- Hartveld L
- Hassan E
- Hawkin P
- Hawkins AT
- Hayati F
- Haynes AB
- Heer B
- Heinius G
- Helminen O
- Heneghan H
- Henriques P
- Henriques S
- Heras Aznar J
- Heritage Emily
- Herman A
- Hernandez Bartolome MA
- Hernandez Gutierrez J
- Hernandez P
- Hernandez R
- Hernández‐García M
- Herrera Mora DR
- Herrero Lopez M
- Herrod P
- Herzberg J
- Hill C
- Hirji S
- Hisham Intisar
- Hmedat A
- Ho D
- Ho MF
- Ho Michael
- Hoffmann PV
- Hogan A
- Hompes R
- Hon S
- Honarpisheh H
- Horn C
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- Hraishawi I
- Huhta H
- Humes D
- Humphreys L
- Hunt A
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- Hussain AH
- Hutchinson Peter
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- Huynh KT
- Hwang Shelley
- I Sharara M
- Iannone I
- Ibrahim AF
- Ibrahim B
- Ibrahim S
- Ibáñez‐Aguirre FJ
- Iflazoğlu N
- Ijichi TR
- Ikram H
- Illingworth B
- Impellizzeri H
- Inama M
- Incollingo P
- Inzunza M
- Ioannidis O
- Iordache N
- Iosifescu RV
- Ip M
- Ipponi P
- Isaac John
- Isik Arda
- Islam AA
- Ismail O
- Isolani SM
- Isoton JC
- Ivancevic N
- Iversen LH
- Izbicki J
- Izzo F
- Jackman J
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- Jain D
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- Jaloun H
- Jamal A
- James A
- Jang S
- Janik M
- Jayarajah U
- Jayasankar B
- Jayasilan J
- Jayasinghe JD
- Jeftic N
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- Jenkinson Michael D
- Jenkinson Michael D
- Jenny HE
- Jeri S
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- Jeyaraj P
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- Jezieniecki C
- Jha M
- Jia F
- Jimenez Higuera E
- Jimenez Miramón J
- Jimenez Ramirez LJ
- Jimenez Toscano M
- Jimenez V
- Jiménez A
- Jobran F
- Jocson R
- Johnstone J
- Jones Conor S
- Jonescheit J
- Jonker Pascal
- Jordan P
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- Jouffret L
- Jover JM
- Jovine E
- JW Wilkin Richard
- Jácome F
- Jäger T
- Kaafarani H
- Kaafarani Haytham MA
- Kacem MJ
- Kakotkin V
- Kalayarasan R
- Kalfountzos C
- Kam da Silva Andrade A
- Kamal M
- Kamal N
- Kamalov A
- Kamarajah Sivesh K
- Kamarajah Sivesh K
- Kamburoğlu MB
- Kamel F
- Kamera BS
- Kamoka E
- Kamphues C
- Kanemitsu Y
- Kannummal Veetil S
- Kanthasamy S
- Kapoor S
- Kappenberger A
- Kara H
- Kara Y
- Karahasanoglu T
- Karaitianos IG
- Karamarkovic A
- Karandikar S
- Karim A
- Karimuddin A
- Karlović D
- Kashif M
- Kasivisvanathan Veeru
- Kassir R
- Katory M
- Kattakayam A
- Katusic Z
- Kaul S
- Kauppila JH
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- Kaushal M
- Kavanagh D
- Kaya T
- Kayyal MY
- Kazachenko E
- Keatley James M
- Kebabçı E
- Kecmanović D
- Keeler BD
- Keller Debby
- Keller Debby
- Kembuan G
- Kenic M
- Kennelly R
- Kent A
- Kerawala AA
- Khajuria A
- Khan A
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- Khan F
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- Khaw Rachel A
- Khokhar MI
- Kiconco H
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- Kilinc Tuncer G
- Killeen S
- Kim NJ
- Kirmizi Y
- Kjaer DW
- Klaristenfeld D
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- Kleeff J
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- Knezevic D
- Knight Andrew
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- Knowles C
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- Kocatas A
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- Konney Thomas
- Konstadoulakis M
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- Koukoulis G
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- Kowalewski P
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- Krdzic I
- Kredan A
- Kretzmer L
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- Kristensen HØ
- Krivokapic Z
- Kroon HM
- Kruijff Schelto
- Kršul D
- Kubiliute E
- Kubyshkin V
- Kucuk GO
- Kudchadkar S
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- Kulle CB
- Kumar A
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- Kutkevičius J
- Kuttanchettiyar KG
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- Kwiatkowski A
- Kyriacou H
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- Königsrainer A
- Küçük IF
- La Regina D
- La Torre F
- Labib PL
- Lacy AM
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- Laface L
- Laforest A
- Laharwal A
- Lakkis Z
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- Landaluce‐olavarria A
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- Larkin J
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- Ledesma FS
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- Leventoglu Sezai
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- Lewis‐Lloyd C
- Li Elizabeth
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- Li M
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- Liao CCL
- Lieske B
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- Lima Buarque I
- Lima da Cruz L
- Lima da Silva C
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- Linari C
- Lippa Laura
- Lira dos Santos Leite A
- Litta F
- Litvin A
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- Litvina Y
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- Lizzi V
- Locatelli A
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- Loehrer A
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- Loncar Z
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- Longstaff L
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- Lora‐Cumplido P
- Lorena Maria Aguilera
- Lorenzon L
- Losada M
- Lott N
- Loubani M
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- Lowery A
- Lozano Lominchar P
- Lucchini SM
- Luglio G
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- Lunevicius R
- Lunghi EG
- Lynch N
- Lyons A
- Lázaro A
- López Antoñanzas L
- Löffler Markus W
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- Löfgren N
- M. elghazaly S
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- Machado D
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- Magee C
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- Magowan D
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- Mahmood M
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- Majumdar KS
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- Marte G
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- Martins A
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- Martín Anoro LF
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- Martínez‐Hurtado E
- Martínez‐Pinedo C
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- Martín‐Arévalo J
- Marx W
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- Marçal A
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- Masciandaro A
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- Massey LH
- Massie E
- Massobrio A
- Mastoridis S
- Math S
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- Matos Costa P
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- McKevitt K
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- Mehigan BJ
- Mehraj A
- Meima‐van Praag EM
- Mekhael M
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- Melenhorst J
- Melhem S
- Memon AS
- Memos N
- Mendes F
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- Mendoza‐Moreno F
- Meneghini S
- Mercado MÁ
- Merdrignac A
- Merh R
- Meriç S
- Messner F
- Metallidis Symeon
- Metwalli M
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- Michalopoulos N
- Michalski C
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- Migliore M
- Mignot G
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- Mihanovic J
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- Miladinov M
- Milanović M
- Milic LJ
- Mills Emily C
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- Milne K
- Minaya Bravo AM
- Minaya‐Bravo Ana
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- Mingoli A
- Minicozzi A
- Minto G
- Mir I
- Mirabella A
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- Mirica RM
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- Mishra N
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- Mitchell D
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- Mitrofan C
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- Miu V
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- Modolo Maria Marta
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- Moftah M
- Moggia E
- Mohamed Sidek AS
- Mohammad Z
- Mohammed MM
- MohammedJibreel M
- Mohan H
- Mohan Helen M
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- Mohd Azman ZA
- Mohd Yunus MF
- Mohsine R
- Mongelli F
- Montauban P
- Montelatici M
- Monteleone M
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- Montori G
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- Moore Rachel
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- Morelli L
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- Morris A
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- Mosley F
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- Moug S
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- Mourad M
- Mshelbwala P
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- Mudawi I
- Muduly D
- Muguerza JM
- Muiesan P
- Mukherjee S
- Muller B
- Mulligan CS
- Mungo S
- Muratore A
- Murawa D
- Murgese A
- Murphy C
- Musetti S
- Mustafa A
- Mutter D
- Muzamil J
- Muñoz Camarena JM
- Muñoz‐Atienza V
- Muñoz‐Bellvis L
- Naar L
- Nacif L
- Nafees Ahmed R
- Nageh MA
- Nahm C
- Najarian M
- Nally D
- Namazov İ
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- Nel D
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- Nepogodiev Dmitri
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- Neri J
- Nespoli LC
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- Ng HJ
- Ng Joe
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- Ng‐Kamstra Joshua S
- Nicolás‐López T
- Nikaj H
- Nikolaou S
- Nikolic S
- Niquen Milagros
- Nisar P
- Nitschke C
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- Nogués A
- Noiret B
- Nolan GJ
- Norcini C
- Nordberg M
- Notte F
- Nouh T
- Novello S
- Novikova A
- Nowak K
- Ntirenganya Faustin
- Nugent E
- Nunes Coelho M
- Nunes R
- Nunez‐Garcia B
- Nunoo‐Mensah JW
- Nuñez Del Barrio H
- Nwabuoku SE
- Núñez J
- Obeidat K
- Ocaña J
- Ochagavía S
- Oguttu B
- Okafor B
- Okunlola A
- Olaogun J
- Olasehinde O
- Oldfield F
- Oliva Mompean F
- Oliveira A
- Olivier J
- Olivieri M
- Olivos Maricarmen
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- Olson KA
- Olute A
- Omar W
- Omeroglu S
- Ong SL
- Onos L
- Oosterlinck W
- Oosterling S
- Opocher E
- Ortega Vázquez I
- Ortiz de Solórzano Aurusa FJ
- Ortiz López D
- Osagie O
- Oseira A
- Osman N
- Osorio Ramos A
- Otero A
- Otoniel LR
- Oussama Kacimi
- Outani Oumaima
- Ovejero Merino E
- Owen H
- Owens P
- Oyende O
- Ozben V
- Ozcelık MF
- Ozgediz D
- Ozmen BB
- O’Brien H
- O’Brien S
- O’Donnell S
- O’Malley S
- O’Riordan J
- O’Shea M
- P Delrio
- Pacheco Sánchez D
- Padilla‐Valverde D
- Padmore G
- Pagano G
- Pajan H
- Palagi S
- Palma P
- Palmeri M
- Panahi P
- Pandey D
- Paniagua García Señorans M
- Papaconstantinou I
- Papadopoulos V
- Papagni V
- Papatheodorou P
- Paquette N
- Parasyris S
- Pareek P
- Pareja Rene
- Parello A
- Parente A
- Parini S
- Parise P
- Park J
- Parkin E
- Parkins K
- Parlanti D
- Parmar C
- Parra Baños PA
- Parray FQ
- Parreira R
- Parreño‐Sacdalan Marie Dione
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- Parseliunas A
- Parwaiz I
- Pasini F
- Paspaliari D
- Pata Francesco
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- Pata Francesco
- Patel Akshay
- Patel K
- Patel M
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- Patrone R
- Patrício B
- Pattyn P
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- Pavlov M
- Pedrazzani C
- Pedro J
- Pedro V
- Peirce C
- Pejnovic L
- Pejovic I
- Pellegrino L
- Pellino G
- Pellino Gianluca
- Peluso C
- Penumadu P
- Pera R
- Peralta Ferreira M
- Pereca J
- Pereira Rodrigues A
- Pereira A
- Pereira C
- Pereira I
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- Perez Gonzalez M
- Perez D
- Pergolini I
- Perivoliotis K
- Peros G
- Perotto LO
- Perra T
- Perrone G
- Persad A
- Persiani R
- Pertile D
- Peteja M
- Petrillo A
- Peyroteo M
- Pezzuto AP
- Peña Ros E
- Peña Soria MJ
- Pham H
- Phan D
- Phang PT
- Phillips E
- Picardo AL
- Picciariello A
- Picciochi Maria
- Pickett L
- Picón Rodríguez R
- Pieniowski E
- Piessen G
- Pina S
- Pinilla Morales RE
- Pinkney Thomas D
- Pinotti E
- Pinto J
- Pipara A
- Piper Rory J
- Pipitone Federico NS
- Pirozzolo G
- Pirzada A
- Pisani Ceretti A
- Pisanu A
- Pius Ogolekwu I
- Pla‐Marti V
- Pockney P
- Pockney Peter
- Pockney Peter
- Pockney Peter
- Podda M
- Poeze M
- Poggioli G
- Police A
- Polydorou A
- Pol‐Fachin L
- Ponchietti L
- Popoola AA
- Porcu A
- Portinari M
- Posadas‐Trujillo OE
- Posma‐Bouman L
- Potter R
- Pourcher G
- Powell S
- Pozotou I
- Praetorius C
- Pramesh CS
- Prando D
- Presl J
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- Prieto Calvo M
- Prieto Nieto MI
- Pronk AJM
- Prosperi P
- Provozina A
- Pruvot FR
- Pujari R
- Pujol Cano N
- Pérez Sánchez MA
- Pérez‐Saborido B
- Qadan M
- Qasem A
- Qatora MS
- Quante M
- Quintana Martinic M
- Quiroga‐Valcárcel A
- Qureshi Ahmad
- Qureshi AU
- Raby‐Smith W
- Radenkovic Dejan
- Raggio E
- Rai L
- Rajan S
- Rajaretnam N
- Rakvin I
- Ramachandran A
- Ramalho de Almeida F
- Ramamoorthy R
- Ramasamy S
- Ramcharan S
- Ramesh P
- Ramirez Faraco M
- Ramirez Romero P
- Ramos Bonilla A
- Ramos D
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- Ramos‐Martín P
- Ramwell A
- Rao S
- Rapaport S
- Rashid A
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- Rasoaherinomenjanahary F
- Rattizzato S
- Ratto C
- Raval M
- Ravindrakumar S
- Ravindran S
- Rayamajhi S
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- Razafindrahita JB
- Recordare A
- Reddy P
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- Rega D
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- Regina de Sampaio L
- Reilly J
- Reim D
- Reinhard T
- Revez T
- Rey Ferro M
- Rey Valcarcel C
- Reynolds IS
- Ribeiro A
- Ribeiro CG
- Ribeiro R
- Ribolla M
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- Riddell A
- Ridgway PF
- Righini E
- Riley C
- Rimonda R
- Ringressi MN
- Ripollés‐Melchor J
- Riquoir Altamirano C
- Risaliti M
- Riva C
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- Rivera‐Alonso D
- Rizk M
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- Robertson Faith
- Robinson A
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- Rodrigo VSD
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- Rodriguez Artigas JM
- Rodriguez JL
- Rodríguez Gómez L
- Rodwell H
- Rogers LJ
- Rogers M
- Rojo López JA
- Roldón Golet M
- Romano M
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- Publication date
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- Field of study
AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease
The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2022
- Field of study
The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery