CONCEPTION ET OPTIMISATION DE PROGRAMMES A OBJETS PARALLELES, REPARTIS ET MULTI-THREADES

NICE-BU Sciences (060882101) / SudocSudocFranceF

Distributed Objects for Parallel Numerical Applications

The C++/

Optimizing metacomputing with communication-computation overlap

Abstract. In the framework of distributed object systems, this paper presents the concepts and an implementation of an overlapping mechanism between communication and computation. This mechanism allows to decrease the execution time of a remote method invocation with parameters of large size. Its implementation and related experiments in the C++/ / language running on top of Globus and Nexus are described

EUROPA Parallel C++ Version 2.1

This paper presents the definition of EUROPA: a framework within which parallel C++ environments can be developed and standardised. EUROPA (also called EC++) sets out a framework which will add portability to parallel C++ systems and will run across a variety of hardware architectures, while encompassing as wide a set of parallel computing models and paradigms as possible, both standard models and user extensible models. This is done entirely within standard C++, i.e. without syntactic extensions to C++

Relation of outcomes to ABC (Atrial Fibrillation Better Care) pathway adherent care in European patients with atrial fibrillation: an analysis from the ESC-EHRA EORP Atrial Fibrillation General Long-Term (AFGen LT) Registry

International audienceAbstract Aims There has been an increasing focus on integrated, multidisciplinary, and holistic care in the treatment of atrial fibrillation (AF). The ‘Atrial Fibrillation Better Care’ (ABC) pathway has been proposed to streamline integrated care in AF. We evaluated the impact on outcomes of an ABC adherent management in a contemporary real-life European-wide AF cohort. Methods and results Patients enrolled in the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry with baseline data to evaluate ABC criteria and available follow-up data were considered for this analysis. Among the original 11 096 AF patients enrolled, 6646 (59.9%) were included in this analysis, of which 1996 (30.0%) managed as ABC adherent. Patients adherent to ABC care had lower CHA2DS2-VASc and HAS-BLED scores (mean ± SD, 2.68 ± 1.57 vs. 3.07 ± 1.90 and 1.26 ± 0.93 vs. 1.58 ± 1.12, respectively; P < 0.001). At 1-year follow-up, patients managed adherent to ABC pathway compared to non-adherent ones had a lower rate of any thromboembolic event (TE)/acute coronary syndrome (ACS)/cardiovascular (CV) death (3.8% vs. 7.6%), CV death (1.9% vs. 4.8%), and all-cause death (3.0% vs. 6.4%) (all P < 0.0001). On Cox multivariable regression analysis, ABC adherent care showed an association with a lower risk of any TE/ACS/CV death [hazard ratio (HR): 0.59, 95% confidence interval (CI): 0.44–0.79], CV death (HR: 0.52, 95% CI: 0.35–0.78), and all-cause death (HR: 0.57, 95% CI: 0.43–0.78). Conclusion In a large contemporary cohort of European AF patients, a clinical management adherent to ABC pathway for integrated care is associated with a significant lower risk for cardiovascular events, CV death, and all-cause death