101 research outputs found
Entwicklungsszenarien einer alpinen Aue bei einem natĂŒrlichen Geschiebedefizit : die Triftaue im Oberhasli
In der zweiten HĂ€lfte des 20. Jahrhunderts hat sich im Zuge des GletscherrĂŒckzugs eine alpine Aue im Triftgebiet gebildet. Zu Beginn prĂ€gten dynamische Geschiebeumlagerungsprozesse die Flusslandschaft am Triftwasser und fĂŒhrten zu einer typischen Sukzession einer alpinen Aue. Mit dem weiteren RĂŒckzug des Triftgletschers hat sich Anfang dieses Jahrhunderts der natĂŒrliche Triftsee gebildet, der einen Geschiebeeintrag in die darunterliegende Triftaue praktisch vollstĂ€ndig unterbindet. Damit wird die Geschiebedynamik im Triftwasser auf ein absolutes Minimum reduziert. Daher ist es dem GewĂ€sser so gut wie nicht mehr möglich, seinen Verlauf im Zuge von Hochwasserereignissen zu verĂ€ndern und neue morphologische Strukturen zu bilden. Aufgrund der topografischen VerhĂ€ltnisse (breiter Kessel) können die natĂŒrlicherweise auftretenden Hochwasserereignisse nicht mehr genug Kraft entwickeln, um grossflĂ€chige VegetationsbestĂ€nde zu entwurzeln. Damit verbunden ist eine rasche Ausbreitung an GrĂŒnerlenbestĂ€nden, die mittelfristig die heutige Triftaue fast vollstĂ€ndig besiedeln werden. Im Rahmen des Triftprojekts (Vergrösserung des Triftsees mit neuem Kraftwerk auf Höhe der bestehenden Triftfassung) wurden u.a. detaillierte Studien zum Ist-Zustand sowie zur Entwicklung der Triftaue mit und ohne Projekt durchgefĂŒhrt. Basierend auf diesen Untersuchungen wurden fĂŒr die Realisierung des Projekts neben dem Restwasserregime zusĂ€tzlich auch Hochwasserdotierungen festgelegt
Mutations in the Catalytic Loop HRD Motif Alter the Activity and Function of Drosophila Src64
The catalytic loop HRD motif is found in most protein kinases and these amino acids are predicted to perform functions in catalysis, transition to, and stabilization of the active conformation of the kinase domain. We have identified mutations in a Drosophila src gene, src64, that alter the three HRD amino acids. We have analyzed the mutants for both biochemical activity and biological function during development. Mutation of the aspartate to asparagine eliminates biological function in cytoskeletal processes and severely reduces fertility, supporting the amino acid's critical role in enzymatic activity. The arginine to cysteine mutation has little to no effect on kinase activity or cytoskeletal reorganization, suggesting that the HRD arginine may not be critical for coordinating phosphotyrosine in the active conformation. The histidine to leucine mutant retains some kinase activity and biological function, suggesting that this amino acid may have a biochemical function in the active kinase that is independent of its side chain hydrogen bonding interactions in the active site. We also describe the phenotypic effects of other mutations in the SH2 and tyrosine kinase domains of src64, and we compare them to the phenotypic effects of the src64 null allele
Conserved Genes Act as Modifiers of Invertebrate SMN Loss of Function Defects
Spinal Muscular Atrophy (SMA) is caused by diminished function of the Survival of Motor Neuron (SMN) protein, but the molecular pathways critical for SMA pathology remain elusive. We have used genetic approaches in invertebrate models to identify conserved SMN loss of function modifier genes. Drosophila melanogaster and Caenorhabditis elegans each have a single gene encoding a protein orthologous to human SMN; diminished function of these invertebrate genes causes lethality and neuromuscular defects. To find genes that modulate SMN function defects across species, two approaches were used. First, a genome-wide RNAi screen for C. elegans SMN modifier genes was undertaken, yielding four genes. Second, we tested the conservation of modifier gene function across species; genes identified in one invertebrate model were tested for function in the other invertebrate model. Drosophila orthologs of two genes, which were identified originally in C. elegans, modified Drosophila SMN loss of function defects. C. elegans orthologs of twelve genes, which were originally identified in a previous Drosophila screen, modified C. elegans SMN loss of function defects. Bioinformatic analysis of the conserved, cross-species, modifier genes suggests that conserved cellular pathways, specifically endocytosis and mRNA regulation, act as critical genetic modifiers of SMN loss of function defects across species
Seasonal-Scale to Decadal-Scale Climatic Variability in Southwest Florida During the Middle Pliocene: Inferences from a Coralline Stable-Isotope Record
We have generated a 49âyearâlong, highâresolution, stable isotope record from a fossil coral, Solenastrea bournoni, to evaluate regional sea surface conditions during the middle Pliocene (3.0 ± 0.5 Ma) in southwest Florida. Continuous routing of the coral slab at an interval of 0.76 mm produced âŒ5 to 6 samples per year. The annual cycle is well defined in ÎŽ18O and ÎŽ13C records confirming the average yearly growth rate estimated from density banding of 4 to 5 mm/yr. Highâdensity bands are synchronous with the highest ÎŽ18O and ÎŽ13C values for 79% and 45% of the annual cycles recorded, respectively. The annual range in ÎŽ18O is 0.70 to 2.27â° and in ÎŽ13C it is 0.31 to 2.21â°. Partitioning of the coral ÎŽ18O signal into sea surface temperature (SST) changes and ÎŽ18Owater changes is difficult to estimate in the ancient. However, isotopic massâbalance calculations, using modern climate data, suggest a partitioning of the ÎŽ18O signal into 8 to 12% salinity and 92 to 88% temperature at the sea surface. If 100% of the ÎŽ18O variation is attributed to temperature, the observed mean annual range in ÎŽ18O (mean = 1.54 ± 0.37â°) corresponds to a seasonal SST range of âŒ7.0 ± 1.7°C (0.22â°/1°C), which is a mean of 3.5°C less than that of the present day. Isotope data are consistent with the hypothesis that ÎŽ13C values covary with the number of sunshine hours. Annually, peak ÎŽ18O values are often observed to precede peak ÎŽ13C values by one sample (i.e., about 2 months). We infer from the isotope pattern that periods of reduced SST were followed about 2 months later by periods of increased number of sunshine hours. This seasonal pattern is similar to that of southwest Florida today. Crossâspectral analysis of fossil coral ÎŽ18O and ÎŽ13C documents coherency peaks, above the 95% confidence interval, at annual and subdecadal frequencies (1.0, 1.6, 2.9 and 5 year). The spectral phase angle between ÎŽ18O and ÎŽ13C at the annual frequency is â60 ± 10°, at the 95% confidence interval. The temporal equivalent of this angle is approximately 2 months, which confirms visual observations of seasonality from the isotope pattern
La description dâimages fixes et en mouvement par deux groupes linguistiques, anglophone et francophone, au QuĂ©bec
Le prĂ©sent article rapporte les rĂ©sultats dâun projet de recherche entrepris dans le cadre dâune sĂ©rie dâĂ©tudes portant sur lâindexation dâimages fixes ou en mouvement. Lâobjectif Ă©tait de dĂ©terminer le niveau dâĂ©quivalence dans le choix dâexpressions verbales pour reprĂ©senter le contenu dâune image entre les termes dâindexation choisis par des francophones et ceux choisis par des anglophones. En comparant les rĂ©sultats obtenus, nous constaterons un rĂ©el degrĂ© de similitude dans la façon de dĂ©crire les images chez les deux groupes linguistiques. De plus, ces rĂ©sultats viennent appuyer lâhypothĂšse voulant que lâindexation dâimages en français pourrait ĂȘtre obtenue Ă partir dâune indexation existante en anglais, et vice versa.The following article reports the results of a research project undertaken as part of a series of studies on the indexation of fixed and moving images. The purpose was to determine the level of equivalence used by francophones and anglophones in the choice of verbal expressions used to summarize the contents of an image. The results show that there is a high degree of similarity in the way images are described by both linguistic groups. Furthermore, these results support the hypothesis that the indexation of images in French can be accomplised using the English terms and vice versa.Este artĂculo presenta los resultados de un proyecto de investigaciĂłn que forma parte de una serie de estudios relacionados con la indizaciĂłn de imĂĄgenes fijas o en movimiento. El objetivo fue determinar el nivel de equivalencia existente dentro de la selecciĂłn de expresiones verbales para representar el contenido de una imagen entre los tĂ©rminos de indizaciĂłn elegidos por los francoparlantes y por los angloparlantes. Al comparar los resultados obtenidos, constatamos que existe una real similitud en la manera de describir las imĂĄgenes en ambos grupos lingĂŒĂsticos. AdemĂĄs, estos resultados apoyan la hipĂłtesis que afirma que la indizaciĂłn de imĂĄgenes en francĂ©s podrĂa obtenerse a partir de una indizaciĂłn existente en inglĂ©s, y viceversa
Soil-plant-atmosphere transfer of organic and metal(oid) pollutants in an industrial and urban area
International audienc
: field monitoring and modelling
International audienceCurrent ÂčÂłâ·Cs levels in French forests are mainly due to global fallouts (GF) from nuclear weapon tests and deposition from Chernobyl accident. Since Fukushima accident, there has been an increasing interest in the behavior of this persistent radionuclide in the soil-tree system at short and mid-term after its deposit (95%) with a weak contribution of the organic layers (<1%).Stand-averaged ÂčÂłâ·Cs activity concentrations in tree organs vary by more than an order of magnitude in the 3 stands, from typically ~0.1 to ~4 Bq/kg dw. The pattern is similar to that observed at short-term after Chernobyl and Fukushima accidents: roots â„ leaves/needles = twigs â„ bark â„ branches = stemwood. In HET and CPS, ÂčÂłâ·Cs and Âč³³Cs concentrations were linearly related (râ„0.9; p<0.001), suggesting a reached equilibrium. Whatever the isotope, the variability observed between individual trees is not correlated to tree characteristics (tree age, DBH or height) and remains under investigation at this stage.Normalized ÂčÂłâ·Cs activity concentrations in stemwood (NC, mÂČ/kg) of beech trees strongly vary between sites, from ~0.7 10^-4 mÂČ/kg at HET site to ~5.1 10^-4 mÂČ/kg at PS site. Such a variability could not be explained by differences in the ÂčÂłâ·Cs soil exchangeable fraction. NC in stemwood of oaks and Scots pines are lower than those of companying beeches (1.1 10^-4 and 0.8 10^-4 mÂČ/kg, respectively). Our results are 1 order of magnitude lower than those observed on the mid-term after Chernobyl, likely indicating a long-term decrease of ÂčÂłâ·Cs bioavailability in soil.Investigations on potassium behavior, estimation of BGC fluxes for ÂčÂłâ·Cs, Âč³³Cs and K, as well as on the selectivity coefficients for transfer processes, are under progress
Soil-plant-atmosphere transfer of organic and metal(oid) pollutants in an industrial and urban area
International audienc
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