Interacción con la Música Flamenca: Análisis y Generación

One main concern in Europe is the preservation and promotion of cultural heritage. Music is a main component of such heritage and flamenco is a main part of Andalusian musical culture. Focusing on flamenco music, in this paper, we describe steps on the analysis and generation of flamenco music oriented towards the diffusion and promotion of this musical style. Specifically, the separation of meaningful musical audio elements from flamenco excerpts by means of the scheme that will be described provides a novel an interactive way of listening to flamenco music by enabling the user to select or emphasize audio elements at will. Also, the scheme for the interactive generation of flamenco music that will be presented allows the user to play and interact with flamenco music by means of a user friendly interface implemented for iOS devices.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech. Ese trabajo ha sido parcialmente financiado por Campus de Excelencia Internacional en Patrimonio, PATRIMONIUN-10, para programas de generación de investigación de referencia internacional en materia de Patrimonio Cultural y Natural, convocatoria realizada en el ámbito del proyecto PATRIMONIUN-10, Jaén, Marzo de 2014, y por el Ministerio de Economía y Competitividad del Gobierno de España, Proyecto TIN2013-47276-C6-2-R

Vibrio vulnificus mutation rate: an in vitro approach

Vibrio vulnificus is a multi-host pathogenic species currently subdivided into five phylogenetic lineages (L) plus one pathovar with the ability to infect fish due to a transmissible virulence plasmid. This plasmid (or a fragment of it) has been transmitted between lineages within the species, contributing to the evolution of V. vulnificus. This study aimed to provide an experimental approximation to the V. vulnificus mutation rate by determining spontaneous mutation rates from bacterial cultures of representants of the different lineages by whole-genome sequencing. To this purpose, synonymous SNP differences, i.e., spontaneous mutation not subjected to the evolutive forces, between initial and final culture after serial growth were evaluated and used for mutation rate calculation

Correlation between biological responses in vitro and in vivo to Ca-doped sol-gel coatings assessed using proteomic analysis

Poor correlation between the results of in vitro testing and the subsequent in vivo experiments hinders the design of biomaterials. Thus, new characterisation methods are needed. This study used proteomic and histological techniques to analyse the effects of Ca-doped biomaterials in vitro and in vivo and verify the correlation between the two systems. The sol-gel route was employed to synthesise coatings functionalised with 0.5 and 5 wt% of CaCl2. Morphology of the coatings was examined using SEM; the Ca2+ ion release from the materials was analysed by means of ICP-AES spectroscopy. The osteogenic and inflammatory responses were inspected in vitro in human osteoblasts (HOb) and TPH-1 monocytes. The in vivo experiments used a rabbit model. The nLC-MS/MS-based proteomic methods were utilised to analyse the proteins adhering to the material samples incubated with human serum or examine protein expression in the tissues close to the implants. Ca-doped biomaterials caused a remarkable increase in the adsorption of coagulation-related proteins, both in vitro (PLMN, THRB, FIBA and VTNC) and in vivo (FBLN1, G1U978). Enhanced affinity to these materials was also observed for proteins involved in inflammation (CO5, C4BPA, IGHM and KV302 in vitro; CARD6, DDOST and CD14 in vivo) and osteogenic functions (TETN, PEDF in vitro; FBN1, AHSG, MYOC in vivo). The results obtained using different techniques were well matched, with a good correlation between the in vitro and in vivo experiments. Thus, the proteomic analysis of biological responses to biomaterials in vitro is a useful tool for predicting their impact in vivo

Application of Multi-core and GPU Architectures on Signal Processing: Case Studies

In this article part of the techniques and developments we are carrying out within the INCO2 group are reported. Results follow the interdisciplinary approach with which we tackle signal processing applications. Chosen case studies show different stages of development: We present algorithms already completed which are being used in practical applications as well as new ideas that may represent a starting point, and which are expected to deliver good results in a short and medium term

Client Applications and Server-Side Docker for Management of RNASeq and/or VariantSeq Workflows and Pipelines of the GPRO Suite

The GPRO suite is an in-progress bioinformatic project for -omics data analysis. As part of the continued growth of this project, we introduce a client- and server-side solution for comparative transcriptomics and analysis of variants. The client-side consists of two Java applications called 'RNASeq' and 'VariantSeq' to manage pipelines and workflows based on the most common command line interface tools for RNA-seq and Variant-seq analysis, respectively. As such, 'RNASeq' and 'VariantSeq' are coupled with a Linux server infrastructure (named GPRO Server-Side) that hosts all dependencies of each application (scripts, databases, and command line interface software). Implementation of the Server-Side requires a Linux operating system, PHP, SQL, Python, bash scripting, and third-party software. The GPRO Server-Side can be installed, via a Docker container, in the user's PC under any operating system or on remote servers, as a cloud solution. 'RNASeq' and 'VariantSeq' are both available as desktop (RCP compilation) and web (RAP compilation) applications. Each application has two execution modes: a step-by-step mode enables each step of the workflow to be executed independently, and a pipeline mode allows all steps to be run sequentially. 'RNASeq' and 'VariantSeq' also feature an experimental, online support system called GENIE that consists of a virtual (chatbot) assistant and a pipeline jobs panel coupled with an expert system. The chatbot can troubleshoot issues with the usage of each tool, the pipeline jobs panel provides information about the status of each computational job executed in the GPRO Server-Side, while the expert system provides the user with a potential recommendation to identify or fix failed analyses. Our solution is a ready-to-use topic specific platform that combines the user-friendliness, robustness, and security of desktop software, with the efficiency of cloud/web applications to manage pipelines and workflows based on command line interface software

Client applications and Server Side docker for management of RNASeq and/or VariantSeq workflows and pipelines of the GPRO Suite

The GPRO suite is an in-progress bioinformatic project for -omic data analyses. As part of the continued growth of this project, we introduce a client side & server side solution for comparative transcriptomics and analysis of variants. The client side consists of two Java applications called "RNASeq" and "VariantSeq" to manage workflows for RNA-seq and Variant-seq analysis, respectively, based on the most common command line interface tools for each topic. Both applications are coupled with a Linux server infrastructure (named GPRO Server Side) that hosts all dependencies of each application (scripts, databases, and command line interface tools). Implementation of the server side requires a Linux operating system, PHP, SQL, Python, bash scripting, and third-party software. The GPRO Server Side can be deployed via a Docker container that can be installed in the user's PC using any operating system or on remote servers as a cloud solution. The two applications are available as desktop and cloud applications and provide two execution modes: a Step-by-Step mode enables each step of a workflow to be executed independently and a Pipeline mode allows all steps to be run sequentially. The two applications also feature an experimental support system called GENIE that consists of a virtual chatbot/assistant and a pipeline jobs panel coupled with an expert system. The chatbot can troubleshoot issues with the usage of each tool, the pipeline job panel provides information about the status of each task executed in the GPRO Server Side, and the expert provides the user with a potential recommendation to identify or fix failed analyses. The two applications and the GPRO Server Side combine the user-friendliness and security of client software with the efficiency of front-end & back-end solutions to manage command line interface software for RNA-seq and variant-seq analysis via interface environments

Correlation between clinical parameters characterising peri-implant and periodontal health : a practice-based research in Spain in a series of patients with implants installed 4-5 years ago

Objectives: To explore peri-implant health (and relation with periodontal status) 4-5 years after implant insertion. Study D esign: A practice-based dental research network multicentre study was performed in 11 Spanish centres. The first patient/month with implant insertion in 2004 was considered. Per patient four teeth (one per quadrant) showing the highest bone loss in the 2004 panoramic X-ray were selected for periodontal status assessment. Bone losses in implants were calculated as the differences between 2004 and 2009 bone levels in radiographs. Results: A total of 117 patients were included. Of the 408 teeth considered, 73 (17.9%) were lost in 2009 (losing risk: >50% for bone losses ?7mm). A total of 295 implants were reviewed. Eight of 117 (6.8%) patients had lost implants (13 of 295 implants installed; 4.4%). Implant loss rate (quadrant status) was 1.4% (edentulous), 3.6% (preserved teeth), and 11.1% (lost teeth) (p=0.037). The percentage of implant loss significantly (p<0.001) increased when the medial/distal bone loss was ?3 mm. The highest (p?0.001) pocket depths were found in teeth with ?5mm and implants with ?3mm bone losses, with similar mean values (?4mm), associated with higher rates of plaque index and bleeding by probing. Conclusions: The significant bi-directional relation between plaque and bone loss, and between each of these two parameters/signs and pocket depths or bleeding (both in teeth and implants, and between them) together with the higher percentage of implants lost when the bone loss of the associated teeth was ?3 mm suggest that the patient?s periodontal status is a critical issue in predicting implant health/lesion

Principal component analysis in ECG signal processing

This paper reviews the current status of principal component analysis in the area of ECG signal processing. The fundamentals of PCA are briefly described and the relationship between PCA and Karhunen-Loeve transform is explained. Aspects on PCA related to data with temporal and spatial correlations are considered as adaptive estimation of principal components is. Several ECG applications are reviewed where PCA techniques have been successfully employed, including data compression, ST-T segment analysis for the detection of myocardial ischemia and abnormalities in ventricular repolarization, extraction of atrial fibrillatory waves for detailed characterization of atrial fibrillation, and analysis of body surface potential maps

Estudio de las preferencias de consumidores y distribuidores especializados respecto del producto ecologico

RESUMEN: La creciente preocupación por la seguridad alimentaria y la mayor sensibilidad al deterioro medioambiental pueden favorecer la expansión de los productos ecológicos. No obstante, el consumo de este tipo de productos no ha crecido al mismo ritmo que la producción. El diferencial de precios respecto de los productos convencionales, los deficientes canales de distribución, y su desconocimiento parecen estar en la raíz del problema. El objetivo de este trabajo se centra en estudiar en profundidad estas limitaciones. Con este fin, se han realizado dos entrevistas, en Pamplona, a los miembros de la cadena agroalimentaria básicos para el posible desarrollo de dicho mercado: consumidores y distribuidores. El primer colectivo se ha segmentado en función de sus actuaciones frente a la alimentación y de sus estilos de vida y el segundo sobre la base de sus actuaciones en la dirección del negocio, con el objeto de delimitar los grupos más interesados en este tipo de productos. A partir de allí, el análisis conjunto ha sido aplicado para identificar la estructura de preferencias en cada segmento y las cuotas de mercado alcanzables por distintos productos bajo escenarios competitivos alternativos. SUMMARY: Increasing concern about food security and environmental conservation might enhance demand for ecological food products. However, consumption has not kept pace with production. Higher prices than conventional food products, distribution deficiencies and lack of knowledge might explain it. The goal of this paper is to analyse those limitations in depth. To attain this objective, two surveys were addressed to consumers and distributors, in Pamplona. These are the two main actors in the agro-food chain involved in the future development of the organic market. Consumers have been segmented according to lifestyles and distributors according to their performance on business administration, in order to define the most interested groups in organic food. Then, conjoint analysis has been applied to identify the preferences structure of each segment. Finally market shares for organic food have been simulated under different scenarios.Organic food products, market segmentation, consumers, distributors, conjoint analysis, Consumer/Household Economics, Q13, R32,

Leopoldo Zea e o movimento latino-americano de História das idéias Leopoldo Zea and the Latin-American movement of History of Ideas

O artigo analisa as etapas de fundação e consolidação de um dos mais importantes movimentos intelectuais da América Latina no século XX - o movimento latino-americano de História das Ideias -, a partir, sobretudo, das ações e escritos de seu principal líder e fundador, o filósofo mexicano Leopoldo Zea Aguilar (1912-2004). Na etapa de fundação, que corresponde à década de 1940, o foco principal é na obra inicial de Zea, bem como em seus primeiros esforços no sentido da articulação e organização institucional do movimento em escala continental. Já na etapa seguinte, que corresponde à década de 1950, é abordado o processo de consolidação orgânica e epistemológica do movimento.<br>This article analyzes the stages of foundation and consolidation of one of the most important intellectual movements of Latin America in the twentieth century - the Latin-American movement of History of Ideas -, starting from actions and writings of its main leader and founder, the Mexican philosopher Leopoldo Zea Aguilar (1912-2004). In the 1940s, during the foundation period, the main focus is on the primary work of Zea, as well as on his first efforts to articulate and organize this movement in continental scale. Moreover, in the following stage held in the 1950s, the process of organic and epistemology consolidation of the movement is invoked