564 research outputs found

    Suelos volcanicos endurecidos

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    In the sedimentary basin of Rieti (Central Italy) a Mollic Fragiudalf was studied in order to verify, through the analysis of differential dissolution kinetics of Si and Al, wether the presence of this two elements could be involved in determining the fragic characters of its deep horizons. The reuslts of the main physico-chemical analysis confirmed the fragic features of the deep horizons Bt3x and Ctgx which have been already observed in the field study. Differential dissolution of Si and Al was performed using 0,5 N NaOH at 25°C, and the values of silica and alumina obtained after each of ten consecutive extractions were cumulated to trace the cumulative curves of dissolution. Slope changes of the curves, which indicate changes in dissolution rate, allowed os to recognize three mineralogical phases with different degree of solubility. The total quantity of SiO2 and Al2O3 dissolved in all the extractions and relative to each of these three phases was estimated, by a graphic method, together with SiO2(Al2O3 molar ratio. This one was indicative of the mineralogical composition and behaviour of each horizon. This study showed an accumulation of free silica which could be present in the form of phytoliths or diatoms as well as a fine precipitate of opal-A and silica-gel in the whole soil, mainly in teh Ap and Ctgx horizons. Moreover neogenesis of clay was more evident in Bt3x horizon. The volcanic origin of the parent material, a trachytic ash fall, probably deposited in a lacustrine environment, could have favoured the availability of Si and the authigenic formation of halloysitic clay from the weathering of galss and feldspars. Our study therefore corroborates the findings of previous studies by Chadwick et al. (1987) and Karathanasis (1989) indicating the important role played by silica, probably as bonding agent, in contributing to produce characteristics of a fragipan. (Résumé d'auteur)

    Evaluation and proposed revisions of criteria for andosols in the world reference base for soil resources

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    The proposed criteria for andosol classification in the World Reference Base (WRB) of Soil Resources were evaluated using the Tohoku University World Andosol Database (TUWAD). The WRB proposal defines a diagnostic andic horizon comprised of vitr-andic, alu-andic, and sil-andic subtypes, and eight second level soil units. Several notable refinements to the WRB criteria were apparent from evaluation of soil properties from TUWAD and are proposed as revised criteria. Our analysis indicated that the most effective criteria for differentiating the andic horizon were glass content, phosphate retention, oxalate extractable Al and Fe, pyrophosphate-extractable Al, and bulk density. The vitr-andic horizon is distinguished by its low degree of weathering, evident from its low oxalate extractable Al and Fe, low P retention, and high glass content. The ratio of pyrophosphate to oxalate extractable Al is used to separate andic horizons dominated by Al-humus, complexes (alu-andic, Al(p)/Al(o) greater or equal than 0.5), from those dominated by allophanic materials (sil-andic, Al(p)/Al(o) < 0.5). When Al(p) data are not availabe, the Si(o) value of 0.6 could be used as an approximate criteria. We also propose revisions to the nine second level soil units based on the dominant pedogenic processes occurring in andosols : non-crystalline material formation and organic matter accumulation. These soil units are based on the degree of weathering (oxalate extractable Al, Fe, glass content), the dominant weathering agent (organic acids vs. carbonic acid), type (melanic or fulvic) and quantity of organic matter, and high 1.5 MPa water-holding capacity. The revised criteria determined by this study effectively differentiate andosols based on their dominant pedogenic processes, and the relationship or soil properties to productivity and utilization. (Résumé d'auteur

    Andosols of the Canary Islands (X). Vitrandepts. Mineralogical characteristics. Their interpretation and classification

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    12 páginas, 8 gráficas.Interpretation, classification and mineralogical characteristics of Vitrandepts are given by the authors. The soils of this group are typically andosoils, with a littie differenciated profil developed on very recent vitric pyroclastic materials. Primary minerals, and volcanic glasses are very abundant in the gross and fine fractions of this soil. Secondary minerals are mainly allophane. Techniques used for mineralogical identifications include X-Ray, Infrared and electron-Microscope.Peer reviewe

    Medical record: systematic centralization versus secure on demand aggregation

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    <p>Abstract</p> <p>Background</p> <p>As patients often see the data of their medical histories scattered among various medical records hosted in several health-care establishments, the purpose of our multidisciplinary study was to define a pragmatic and secure on-demand based system able to gather this information, with no risk of breaching confidentiality, and to relay it to a medical professional who asked for the information via a specific search engine.</p> <p>Methods</p> <p>Scattered data are often heterogeneous, which makes the task of gathering information very hard. Two methods can be compared: trying to solve the problem by standardizing and centralizing all the information about every patient in a single Medical Record system or trying to use the data "as is" and find a way to obtain the most complete and the most accurate information. Given the failure of the first approach, due to the lack of standardization or privacy and security problems, for example, we propose an alternative that relies on the current state of affairs: an on-demand system, using a specific search engine that is able to retrieve information from the different medical records of a single patient.</p> <p>Results</p> <p>We describe the function of Medical Record Search Engines (MRSE), which are able to retrieve all the available information regarding a patient who has been hospitalized in different hospitals and to provide this information to health professionals upon request. MRSEs use pseudonymized patient identities and thus never have access to the patient's identity. However, though the system would be easy to implement as it by-passes many of the difficulties associated with a centralized architecture, the health professional would have to validate the information, i.e. read all of the information and create his own synthesis and possibly reject extra data, which could be a drawback. We thus propose various feasible improvements, based on the implementation of several tools in our on-demand based system.</p> <p>Conclusions</p> <p>A system that gathers all of the currently available information regarding a patient on the request of health-care professionals could be of great interest. This low-cost pragmatic alternative to centralized medical records could be developed quickly and easily. It could also be designed to include extra features and should thus be considered by health authorities.</p

    Brain metastases at the time of presentation of non-small cell lung cancer: a multi-centric AERIO analysis of prognostic factors

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    A multi-centre retrospective study involving 4 French university institutions has been conducted in order to identify routine pre-therapeutic prognostic factors of survival in patients with previously untreated non-small cell lung cancer and brain metastases at the time of presentation. A total of 231 patients were recorded regarding their clinical, radiological and biological characteristics at presentation. The accrual period was January 1991 to December 1998. Prognosis was analysed using both univariate and multivariate (Cox model) statistics. The median survival of the whole population was 28 weeks. Univariate analysis (log-rank), showed that patients affected by one of the following characteristics proved to have a shorter survival in comparison with the opposite status of each variable: male gender, age over 63 years, poor performance status, neurological symptoms, serum neuron-specific enolase (NSE) level higher than 12.5 ng ml−1, high serum alkaline phosphatase level, high serum LDH level and serum sodium level below 132 mmol l−1. In the Cox's model, the following variables were independent determinants of a poor outcome: male gender: hazard ratio (95% confidence interval): 2.29 (1.26–4.16), poor performance status: 1.73 (1.15–2.62), age: 1.02 (1.003–1.043), a high serum NSE level: 1.72 (1.11–2.68), neurological symptoms: 1.63 (1.05–2.54), and a low serum sodium level: 2.99 (1.17–7.62). Apart from 4 prognostic factors shared in common with other stage IV NSCLC patients, whatever the metastatic site (namely sex, age, gender, performance status and serum sodium level) this study discloses 2 determinants specifically resulting from brain metastasis: i.e. the presence of neurological symptoms and a high serum NSE level. The latter factor could be in relationship with the extent of normal brain tissue damage caused by the tumour as has been demonstrated after strokes. Additionally, the observation of a high NSE level as a prognostic determinant in NSCLC might reflect tumour heterogeneity and understimated neuroendocrine differentiation. © 2001 Cancer Research Campaignhttp://www.bjcancer.co

    The PanCam Instrument for the ExoMars Rover

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    The scientific objectives of the ExoMars rover are designed to answer several key questions in the search for life on Mars. In particular, the unique subsurface drill will address some of these, such as the possible existence and stability of subsurface organics. PanCam will establish the surface geological and morphological context for the mission, working in collaboration with other context instruments. Here, we describe the PanCam scientific objectives in geology, atmospheric science, and 3-D vision. We discuss the design of PanCam, which includes a stereo pair of Wide Angle Cameras (WACs), each of which has an 11-position filter wheel and a High Resolution Camera (HRC) for high-resolution investigations of rock texture at a distance. The cameras and electronics are housed in an optical bench that provides the mechanical interface to the rover mast and a planetary protection barrier. The electronic interface is via the PanCam Interface Unit (PIU), and power conditioning is via a DC-DC converter. PanCam also includes a calibration target mounted on the rover deck for radiometric calibration, fiducial markers for geometric calibration, and a rover inspection mirror.publishersversionPeer reviewe

    Some methods for blindfolded record linkage

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    BACKGROUND: The linkage of records which refer to the same entity in separate data collections is a common requirement in public health and biomedical research. Traditionally, record linkage techniques have required that all the identifying data in which links are sought be revealed to at least one party, often a third party. This necessarily invades personal privacy and requires complete trust in the intentions of that party and their ability to maintain security and confidentiality. Dusserre, Quantin, Bouzelat and colleagues have demonstrated that it is possible to use secure one-way hash transformations to carry out follow-up epidemiological studies without any party having to reveal identifying information about any of the subjects – a technique which we refer to as "blindfolded record linkage". A limitation of their method is that only exact comparisons of values are possible, although phonetic encoding of names and other strings can be used to allow for some types of typographical variation and data errors. METHODS: A method is described which permits the calculation of a general similarity measure, the n-gram score, without having to reveal the data being compared, albeit at some cost in computation and data communication. This method can be combined with public key cryptography and automatic estimation of linkage model parameters to create an overall system for blindfolded record linkage. RESULTS: The system described offers good protection against misdeeds or security failures by any one party, but remains vulnerable to collusion between or simultaneous compromise of two or more parties involved in the linkage operation. In order to reduce the likelihood of this, the use of last-minute allocation of tasks to substitutable servers is proposed. Proof-of-concept computer programmes written in the Python programming language are provided to illustrate the similarity comparison protocol. CONCLUSION: Although the protocols described in this paper are not unconditionally secure, they do suggest the feasibility, with the aid of modern cryptographic techniques and high speed communication networks, of a general purpose probabilistic record linkage system which permits record linkage studies to be carried out with negligible risk of invasion of personal privacy

    Episiotomy practices in France: epidemiology and risk factors in non-operative vaginal deliveries

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    Episiotomy use has decreased due to the lack of evidence on its protective effects from maternal obstetric anal sphincter injuries. Indications for episiotomy vary considerably and there are a great variety of factors associated with its use. The aim of this article is to describe the episiotomy rate in France between 2013 and 2017 and the factors associated with its use in non-operative vaginal deliveries. In this retrospective population-based cohort study, we included vaginal deliveries performed in French hospitals (N= 584) and for which parity was coded. The variable of interest was the rate of episiotomy, particularly for non-operative vaginal deliveries. Trends in the episiotomy rates were studied using the Cochran-Armitage test. Hierarchical logistic regression was used to identify variables associated with episiotomy according to maternal age and parity. Between 2013 and 2017, French episiotomy rates fell from 21.6 to 14.3% for all vaginal deliveries (p< 0.01), and from 15.5 to 9.3% (p< 0.01) for all non-operative vaginal deliveries. Among non-operative vaginal deliveries, epidural analgesia, non-reassuring fetal heart rate, meconium in the amniotic fluid, shoulder dystocia, and newborn weight (≥4,000 g) were risk factors for episiotomy, both for nulliparous and multiparous women. On the contrary, prematurity reduced the risk of its use. For nulliparous women, breech presentation was also a risk factor for episiotomy, and for multiparous women, scarred uterus and multiple pregnancies were risk factors. In France, despite a reduction in episiotomy use over the last few years, the factors associated with episiotomy have not changed and are similar to the literature. This suggests that the decrease in episiotomies in France is an overall tendency which is probably related to improved care strategies that have been relayed by hospital teams and perinatal networks
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