Europium(III) Macrocyclic Chelates Appended with Tyrosine-based Chromophores and Di-(2-picolyl)amine-based Receptors: Turn-On Luminescent Chemosensors Selective to Zinc(II) Ions

[Abstract] Zinc ions play an important role in many biological processes in the human body. To selectively detect Zn²⁺, two EuDO3A‐based complexes (DO3A=1,4,7,10‐tetraazacyclododecane‐1,4,7‐tricarboxylic acid) appended with tyrosine as a chromophore and di‐(2‐picolyl)amine (DPA) as the Zn²⁺ recognition moiety were developed as suitable luminescent sensors. Their luminescence intensity is affected by the photoinduced electron transfer mechanism. Upon addition of Zn²⁺, both probes display an up to sevenfold enhancement in Eu³⁺ emission. Competition experiments demonstrated their specificity toward Zn²⁺ over other metal ions, while also revealing the nonspecificity of the derivatives lacking the DPA‐moiety, thus confirming the essential role of the DPA for the recognition of Zn²⁺. The induced emission changes of Eu³⁺ allow for precise quantitative analysis of Zn²⁺, establishing these lanthanide‐based complexes as viable chemosensors for biological applications.German Research Foundation; AN 716/7-

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Luces sobre sombras: Las precursoras cinematográficas afroamericanas

Como directoras, guionistas, productoras y distribuidoras, las mujeres afroamericanas contribuyeron de manera decisiva en los orígenes de la industria cinematográfica estadounidense. La escala de valores del heteropatriarcado occidental que aún domina el negocio destinó durante casi un siglo a estas pioneras y sus trabajos a un severo oscurantismo del cual comenzaron a emerger a finales del siglo XX a través de las investigaciones realizadas por varias historiadoras, cineastas y críticas afroamericanas. En esta comunicación pondré en valor las aportaciones de estas precursoras al desarrollo del cine estadounidense como contribuciones fundamentales a la representación de la diversidad de raza, género y claseAs directors, scriptwriters, producers and distributors, African American women played a decisive role in the origin of the motion pictures industry in the United States. For almost a century, the white patriarchal values that still dominate the business have sent these pioneers and their works to a severe obscurantism. The research initiated by African American women historians, filmmakers and critics by the end of the 20th century brought to the forefront these pioneers and their works. This paper offers a brief introduction to these cinematic foremothers as fundamental figures in the cinema of the United States offering varied representations of race, gender and class

Colaboración con Centroamérica atiende grupos en vulnerabilidad

La propuesta se fundamenta en que el prefigurar acciones específicas de prevención hacia grupos altamente vulnerable por discapacitaciones físicas, considerando las características de las regiones en interacción con otros de alta marginación socio-econónomica, ha sido prácticamente soslayado

La Biblioteca Digital Ovidiana y el patrimonio bibliográfico español

This article discusses objectives and the development of the Ovidian Digital Library in relation to the study and dissemination of Spanish bibliographic heritage, showing the new research involved the illustrated editions, the study of the specimens and treatment data and digital materials as a new proposal in relation to the bibliographic information guarded in Spanish libraries collected and accessible via Catálogo Colectivo del Patrimonio Bibliográfico Español.En este artículo se expondrán los objetivos y el desarrollo de las novedades de la Biblioteca Digital Ovidiana en relación con el estudio y la difusión del patrimonio bibliográfico español, mostrando las novedades que entraña la investigación sobre las ediciones ilustradas, el estudio de los ejemplares y el tratamiento de los datos y los materiales digitales como una propuesta nueva en la relación con la información bibliográfica del fondo antiguo custodiado en las bibliotecas españolas recogido y accesible a través del Catálogo Colectivo del Patrimonio Bibliográfico Español

Purification and biological characterization of halocin H1 from Haloferax mediterranei M2a

The production of halocins, bacteriocin-like proteins of ecological significance, is a frequent characteristic of species from the family Halobacteriaceae. Halocin H1, produced by Haloferax mediterranei strain M2a, is a single 31-kDa polypeptide. Its purification was achieved by combining two chromatographic systems: Sepharose 4B linked to bacitracin followed by hydroxylapatite Bio-gel HTP. Halocin H1 required concentrations of NaCl higher than 1.5 M to maintain its activity. Haoarchaeal strains showed a differential degree of sensitivity to the action of this halocin

High diversity and morphological convergence among melanised fungi from rock formations in the Central Mountain System of Spain

Melanised fungi were isolated from rock surfaces in the Central Mountain System of Spain. Two hundred sixty six isolates were recovered from four geologically and topographically distinct sites. Microsatellite-primed PCR techniques were used to group isolates into genotypes assumed to represent species. One hundred and sixty three genotypes were characterised from the four sites. Only five genotypes were common to two or more sites. Morphological and molecular data were used to characterise and identify representative strains, but morphology rarely provided a definitive identification due to the scarce differentiation of the fungal structures or the apparent novelty of the isolates. Vegetative states of fungi prevailed in culture and in many cases could not be reliably distinguished without sequence data. Morphological characters that were widespread among the isolates included scarce micronematous conidial states, endoconidia, mycelia with dark olive-green or black hyphae, and mycelia with torulose, isodiametric or moniliform hyphae whose cells develop one or more transverse and/or oblique septa. In many of the strains, mature hyphae disarticulated, suggesting asexual reproduction by a thallic micronematous conidiogenesis or by simple fragmentation. Sequencing of the internal transcribed spacers (ITS1, ITS2) and 5.8S rDNA gene were employed to investigate the phylogenetic affinities of the isolates. According to ITS sequence alignments, the majority of the isolates could be grouped among four main orders of Pezizomycotina: Pleosporales, Dothideales, Capnodiales, and Chaetothyriales. Ubiquitous known soil and epiphytic fungi species were generally absent from the rock surfaces. In part, the mycota of the rock surfaces shared similar elements with melanised fungi from plant surfaces and fungi described from rock formations in Europe and Antarctica. The possibility that some of the fungi were lichen mycobionts or lichen parasites could not be ruled out

Naturaleza y femineidad. Los epítetos de las Ninfas en la épica griega arcaica

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