256 research outputs found
Congestion and residential moving behaviour
In this paper we study how congestion and residential movingbehaviour are interrelated using a two-region job search model. Workerschoose optimally between interregional commuting and residential movingto live closer to the place of work. This choice affects the external costs ofcommuting due to congestion. The welfare maximizing road tax is derived.We demonstrate that road pricing may not only reduce congestion but alsoincrease total residential moving costs in the economy. One of the mainconsequences is that the road tax does not necessarily increase welfare
Wages and commuting:quasi-natural experiments' evidence from firms that relocate
We examine the causal effect of commuting distance on workers' wages in a quasi-natural experiments setting using information on all workers in Denmark. We account for endogeneity of distance by using changes in distance that are due to firms' relocations. For the range of commuting distances where income tax reductions associated with commuting do not apply, one kilometre increase in commuting distance induces a wage increase of about 0.42%, suggesting an hourly compensation of about half of the hourly net wage. Our findings are consistent with wage bargaining theory and suggest a bargaining power parameter of about 0.50. Due to the experimental setup we are able to exclude many competing explanations of the wage-distance relationship
Pure stands of temperate forest tree species modify soil respiration and N turnover
International audienceThe effects of five different tree species common in the temperate zone, i.e. beech (Fagus sylvatica L.), pedunculate oak (Quercus robur L.), Norway spruce (Picea abies [L.] Karst), Japanese larch (Larix leptolepis [Sichold and Zucc.] Gordon) and mountain pine (Pinus mugo Turra), on soil respiration, gross N mineralization and gross nitrification rates were investigated. Soils were sampled in spring and summer 2002 at a forest trial in Western Jutland, Denmark, where pure stands of the five tree species of the same age were growing on the same soil. Soil respiration, gross rates of N mineralization and nitrification were significantly higher in the organic layers than in the Ah horizons for all tree species and both sampling dates. In summer (July), the highest rates of soil respiration, gross N mineralization and gross nitrification were found in the organic layer under spruce, followed by beech > larch > oak > pine. In spring (April), these rates were also higher under spruce compared to the other tree species, but were significantly lower than in summer. For the Ah horizons no clear seasonal trend was observed for any of the processes examined. A linear relationship between soil respiration and gross N mineralization (r2=0.77), gross N mineralization and gross nitrification rates (r2=0.72), and between soil respiration and gross nitrification (r2=0.81) was found. The results obtained underline the importance of considering the effect of forest type on soil C and N transformations
Ammonium chloride ingestion attenuates exercise-induced mRNA levels in human muscle
Minimizing the decrease in intracellular pH during high-intensity exercise training promotes greater improvements in mitochondrial respiration. This raises the intriguing hypothesis that pH may affect the exercise-induced transcription of genes that regulate mitochondrial biogenesis. Eight males performed 10x2-min cycle intervals at 80% VO2speak intensity on two occasions separated by ~2 weeks. Participants ingested either ammonium chloride (ACID) or calcium carbonate (PLA) the day before and on the day of the exercise trial in a randomized, counterbalanced order, using a crossover design. Biopsies were taken from the vastus lateralis muscle before and after exercise. The mRNA level of peroxisome proliferator-activated receptor co-activator 1α (PGC-1α), citrate synthase, cytochome c and FOXO1 was elevated at rest following ACID (P<0.05). During the PLA condition, the mRNA content of mitochondrial- and glucose-regulating proteins was elevated immediately following exercise (P<0.05). In the early phase (0-2 h) of post-exercise recovery during ACID, PGC-1α, citrate synthase, cytochome C, FOXO1, GLUT4, and HKII mRNA levels were not different from resting levels (P>0.05); the difference in PGC-1α mRNA content 2 h post-exercise between ACID and PLA was not significant (P = 0.08). Thus, metabolic acidosis abolished the early post-exercise increase of PGC-1α mRNA and the mRNA of downstream mitochondrial and glucose-regulating proteins. These findings indicate that metabolic acidosis may affect mitochondrial biogenesis, with divergent responses in resting and post-exercise skeletal muscle
A Taxonomy of Causality-Based Biological Properties
We formally characterize a set of causality-based properties of metabolic
networks. This set of properties aims at making precise several notions on the
production of metabolites, which are familiar in the biologists' terminology.
From a theoretical point of view, biochemical reactions are abstractly
represented as causal implications and the produced metabolites as causal
consequences of the implication representing the corresponding reaction. The
fact that a reactant is produced is represented by means of the chain of
reactions that have made it exist. Such representation abstracts away from
quantities, stoichiometric and thermodynamic parameters and constitutes the
basis for the characterization of our properties. Moreover, we propose an
effective method for verifying our properties based on an abstract model of
system dynamics. This consists of a new abstract semantics for the system seen
as a concurrent network and expressed using the Chemical Ground Form calculus.
We illustrate an application of this framework to a portion of a real
metabolic pathway
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