8 research outputs found
IMPLEMENTASI KETENTUAN UPAH MINIMUM PROVINSI SULAWESI UTARA DALAM UPAYA MENIGKATKAN KESEJAHTERAAN BURUH
Penelitian ini bertujuan untuk memahami dan mengkaji pengaturan hukum tentang sistem Pengupahan menurut UU No. 13 Tahun 2003 Tentang Ketenagakerjaan dan untuk mengetahui pelaksanaan sistem pengupahan di Propinsi Sulawesi Utara. Dengan menggunakan metode penelitian normatif, maka berdasarkan hasil penelitian penulis dapat ditarik kesimpulan yaitu : 1. Landasan hukum konsep perhitungan Komponen Upah Minimum Provinsi secara substansi telah diatur dalam Undang-undang No. 13 Tahun 2003 tentang Ketenagakerjaan yang pada intinya menyatakan bahwa setiap pekerja/buruh berhak memperoleh penghasilan yang memenuhi penghidupan yang layak bagi kemanusiaan, komponen upah meliputi upah minimum, upah kerja lembur dan lain-lain. Kemudian dalam Peraturan Menteri Tenaga Kerja dan Transmigrasi Nomor 7 Tahun 2013 tentang Upah Minimum. 2. Implementasi penetapan upah minimum Provinsi Sulawesi Utara berdasarkan Undang-undang No. 13 Tahun 2003 tentang Ketenagakerjaan diatur dalam pasal 88 ayat 3 huruf dan ayat 4 serta pasal 89. Bahwa Upah Minimum ditetapkan Gubernur berdasarkan kebutuhan hidup layak sebagaimana yang diatur dalam Keputusan Menteri Tenaga Kerja Nomor 13 Tahun 2012 tentang Komponen dan Pelaksanaan Tahapan Pencapaian Kebutuhan Hidup Layak, dengan memperhatikan produktifitas dan pertumbuhan ekonomi berdasarkan rekomendasi Dewan Pengupahan Provinsi yang didasarkan pada Peraturan Menteri Tenaga Kerja Dan Transmigrasi No. 7 Tahun 2013 tentang Upah Minimum.
Kata Kunci : Buruh, UMP, Sulu
Response regarding inflammation as a predictor of depression in heart failure
The main criticisms by Glover and colleagues of our “Short Report” (Wirtz et al., 2009) relate primarily to the fact that our study was exploratory, which is fully acknowledged in the paper. However, the point of publishing an exploratory paper is to allow other researchers to view provocative preliminary findings in order to gain insight into promising avenues of investigation. We reported that the circulating inflammatory biomarker sICAM-1 independently predicted depression severity (as assessed by the Beck Depression Inventory (BDI)) in a prospective design at both 12 and 18 months later in 30 heart failure (HF) patients. We controlled for cardiovascular risk factors, indicators of HF severity, and medication intake. This finding potentially suggests that vascular inflammation precedes depression in HF patients. Glover et al. have apparently misunderstood that our findings are limited to HF patients since they attempted negate our findings by using examples from other populations
Depressive symptoms are associated with soluble P-selectin reactivity to acute exercise in heart failure
BACKGROUND: To determine the effects of depressive symptom severity on the circulating soluble adhesion molecule response to an acute exercise challenge in patients with heart failure (HF) compared with control subjects. METHODS: Thirty-eight male HF patients and 19 male control subjects (mean age +/- SEM: 55.5 +/- 1.9) completed the Beck Depression Inventory (BDI) before undergoing a moderate 20-minute bicycle exercise at approximately 65% to 70% VO(2peak). Plasma levels of the soluble adhesion molecules P-selectin (sP-selectin) (sCD62P) and soluble intercellular adhesion molecule-1 (sICAM-1) were determined immediately before and after and 10 minutes after exercise. RESULTS: Higher BDI scores moderated greater increases in sP-selectin levels in response to exercise over time in HF patients as compared with control subjects [F(1.8/84.5) = 3.25, p = .05]. Post hoc testing revealed that in HF patients, but not in control subjects, higher BDI scores were significantly associated with greater increases in sP-selectin levels over time in response to exercise [BDI by exercise interaction: F(1.6/49.6) = 5.67, p = .010]. Also, in HF patients, but not in control subjects, higher BDI scores were associated with higher sP-selectin levels at pre-exercise and postexercise time points [main effect BDI: F(1/31) = 4.86, p = .035]. CONCLUSIONS: Our findings suggest that in male HF patients with increasing depressive symptom severity, levels of the adhesion molecule sP-selectin are higher before and after exercise and have greater increases in response to exercise. This could have implications for acute coronary syndromes associated with exercise and thereby may impact mortality
Microbiological testing of adults hospitalised with community-acquired pneumonia: an international study
This study aimed to describe real-life microbiological testing of adults hospitalised with community-acquired pneumonia (CAP) and to assess concordance with the 2007 Infectious Diseases Society of America (IDSA)/American Thoracic Society (ATS) and 2011 European Respiratory Society (ERS) CAP guidelines. This was a cohort study based on the Global Initiative for Methicillin-resistant Staphylococcus aureus Pneumonia (GLIMP) database, which contains point-prevalence data on adults hospitalised with CAP across 54 countries during 2015. In total, 3702 patients were included. Testing was performed in 3217 patients, and included blood culture (71.1%), sputum culture (61.8%), Legionella urinary antigen test (30.1%), pneumococcal urinary antigen test (30.0%), viral testing (14.9%), acute-phase serology (8.8%), bronchoalveolar lavage culture (8.4%) and pleural fluid culture (3.2%). A pathogen was detected in 1173 (36.5%) patients. Testing attitudes varied significantly according to geography and disease severity. Testing was concordant with IDSA/ATS and ERS guidelines in 16.7% and 23.9% of patients, respectively. IDSA/ATS concordance was higher in Europe than in North America (21.5% versus 9.8%; p<0.01), while ERS concordance was higher in North America than in Europe (33.5% versus 19.5%; p<0.01). Testing practices of adults hospitalised with CAP varied significantly by geography and disease severity. There was a wide discordance between real-life testing practices and IDSA/ATS/ERS guideline recommendations
Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
BACKGROUND:
The correct management of immunocompromised patients with pneumonia is debated. We evaluated the prevalence, risk factors, and characteristics of immunocompromised patients coming from the community with pneumonia.
METHODS:
We conducted a secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia and hospitalized in 222 hospitals in 54 countries worldwide. Risk factors for immunocompromise included AIDS, aplastic anemia, asplenia, hematological cancer, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroid use, and solid tumor.
RESULTS:
At least 1 risk factor for immunocompromise was recorded in 18% of the 3702 patients enrolled. The prevalences of risk factors significantly differed across continents and countries, with chronic steroid use (45%), hematological cancer (25%), and chemotherapy (22%) the most common. Among immunocompromised patients, community-acquired pneumonia (CAP) pathogens were the most frequently identified, and prevalences did not differ from those in immunocompetent patients. Risk factors for immunocompromise were independently associated with neither Pseudomonas aeruginosa nor non-community-acquired bacteria. Specific risk factors were independently associated with fungal infections (odds ratio for AIDS and hematological cancer, 15.10 and 4.65, respectively; both P = .001), mycobacterial infections (AIDS; P = .006), and viral infections other than influenza (hematological cancer, 5.49; P < .001).
CONCLUSIONS:
Our findings could be considered by clinicians in prescribing empiric antibiotic therapy for CAP in immunocompromised patients. Patients with AIDS and hematological cancer admitted with CAP may have higher prevalences of fungi, mycobacteria, and noninfluenza viruses
International prevalence and risk factors evaluation for drug-resistant Streptococcus pneumoniae pneumonia
Objective: Streptococcus pneumoniae is the most frequent bacterial pathogen isolated in subjects with Community-acquired pneumonia (CAP) worldwide. Limited data are available regarding the current global burden and risk factors associated with drug-resistant Streptococcus pneumoniae (DRSP) in CAP subjects. We assessed the multinational prevalence and risk factors for DRSP-CAP in a multinational point-prevalence study.
Design: The prevalence of DRSP-CAP was assessed by identification of DRSP in blood or respiratory samples among adults hospitalized with CAP in 54 countries. Prevalence and risk factors were compared among subjects that had microbiological testing and antibiotic susceptibility data. Multivariate logistic regressions were used to identify risk factors independently associated with DRSP-CAP.
Results: 3,193 subjects were included in the study. The global prevalence of DRSP-CAP was 1.3% and continental prevalence rates were 7.0% in Africa, 1.2% in Asia, and 1.0% in South America, Europe, and North America, respectively. Macrolide resistance was most frequently identified in subjects with DRSP-CAP (0.6%) followed by penicillin resistance (0.5%). Subjects in Africa were more likely to have DRSP-CAP (OR: 7.6; 95% CI: 3.34-15.35, p < 0.001) when compared to centres representing other continents.
Conclusions: This multinational point-prevalence study found a low global prevalence of DRSP-CAP that may impact guideline development and antimicrobial policies. Published by Elsevier Ltd on behalf of The British Infection Association
Aspiration risk factors, microbiology, and empiric antibiotics for patients hospitalized with community-acquired pneumonia
Background: Aspiration community-acquired pneumonia (ACAP) and community-acquired pneumonia (CAP) in patients with aspiration risk factors (AspRFs) are infections associated with anaerobes, but limited evidence suggests their pathogenic role. Research question: What are the aspiration risk factors, microbiology patterns, and empiric anti-anaerobic use in patients hospitalized with CAP? Study design and methods: This is a secondary analysis of GLIMP, an international, multicenter, point-prevalence study of adults hospitalized with CAP. Patients were stratified into three groups: (1) ACAP, (2) CAP/AspRF+ (CAP with AspRF), and (3) CAP/AspRF- (CAP without AspRF). Data on demographics, comorbidities, microbiological results, and anti-anaerobic antibiotics were analyzed in all groups. Patients were further stratified in severe and nonsevere CAP groups. Results: We enrolled 2,606 patients with CAP, of which 193 (7.4%) had ACAP. Risk factors independently associated with ACAP were male, bedridden, underweight, a nursing home resident, and having a history of stroke, dementia, mental illness, and enteral tube feeding. Among non-ACAP patients, 1,709 (70.8%) had CAP/AspRF+ and 704 (29.2%) had CAP/AspRF-. Microbiology patterns including anaerobes were similar between CAP/AspRF-, CAP/AspRF+ and ACAP (0.0% vs 1.03% vs 1.64%). Patients with severe ACAP had higher rates of total gram-negative bacteria (64.3% vs 44.3% vs 33.3%, P = .021) and lower rates of total gram-positive bacteria (7.1% vs 38.1% vs 50.0%, P 50% in all groups) independent of AspRFs or ACAP received specific or broad-spectrum anti-anaerobic coverage antibiotics. Interpretation: Hospitalized patients with ACAP or CAP/AspRF+ had similar anaerobic flora compared with patients without aspiration risk factors. Gram-negative bacteria were more prevalent in patients with severe ACAP. Despite having similar microbiological flora between groups, a large proportion of CAP patients received anti-anaerobic antibiotic coverage