43 research outputs found

    Predicting Customer Preference of Mobile Service using Neural Network

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    In countries where several Mobile Communication Service providers operate, it is imperative on the service providers to recognize the aspects of their services that will attract new customers in order to help them stay on top of the competition. This is known to be expensive in terms of money and time. To address this problem, we present a Feed-forward Back-propagation Neural Network (FBNN) that is aimed at learning potential customersā€™ ā€œwould-beā€ pattern of choosing a Mobile Service based on selected criteria. The Neural Network is tested on sample data and predictions made to the same effect as already mentioned. The results show that the Neural Network is adequate for predicting customer preference of a mobile service. This research concentrates on predicting new customer preferences as opposed to the popular notion of models predicting (existing) customer churn. Keywords: Feed-forward Back-propagation, Mobile Service Provider, Neural Network, Prediction

    Mining Studentsā€™ Messages to Discover Problems Associated with Academic Learning

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    WhatsApp has become the preferred choice of students for sending messages in developing countries. Due to its privacy and the ability to create groups, students are able to express their ā€œfeelingsā€ to peers without fear. To obtain immediate feedback on problems hindering effective learning, supervised learning algorithms were applied to mine the sentiments in WhatsApp group messages of University students. An ensemble classifier made up of NaĆÆve Bayes, Support Vector Machines, and Decision Trees outperformed the individual classifiers in predicting the mood of students with an accuracy of 0.76, 0.92 recall, 0.72 precision and 0.80 F-score. These results show that we can predict the mood and emotions of students towards academic learning from their private messages. The method is therefore proposed as one of the effective ways by which educational authorities can cost effectively monitor issues hindering studentsā€™ academic learning and by extension their academic progress. Keywords: WhatsApp; Sentiments; Ensemble; Classification; NaĆÆve Bayes; Support Vector Machines.

    Clinicopathologic characteristics of early-onset breast cancer: a comparative analysis of cases from across Ghana

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    BACKGROUND: Breast cancer is the commonest cancer diagnosed globally and the second leading cause of cancer-related mortality among women younger than 40 years. This study comparatively reviewed the demographic, pathologic and molecular features of Early-Onset Breast Cancer (EOBC) reported in Ghana in relation to Late Onset Breast Cancer (LOBC). METHODS: A descriptive, cross-sectional design was used, with purposive sampling of retrospective histopathology data from 2019 to 2021. Reports of core or incision biopsy, Wide Local Excision or Mastectomy with or without axillary lymph node dissection specimen and matched immunohistochemistry reports were merged into a single file and analysed with SPSS v. 20.0. Descriptive statistics of frequencies and percentages were used to describe categorical variables. Cross-tabulation and chi-square test was done at a 95% confidence interval with significance established at pā€‰\u3cā€‰0.05. RESULTS: A total of 2418 cases were included in the study with 20.2% (488 cases) being EOBCs and 79.8% (1930 cases) being LOBCs. The median age at diagnosis was 34.66 (IQR: 5.55) in the EOBC group (\u3cā€‰40 years) and 54.29 (IQR: 16.86) in the LOBC group (ā‰„ā€‰40 years). Invasive carcinoma-No Special Type was the commonest tumour type with grade III tumours being the commonest in both categories of patients. Perineural invasion was the only statistically significant pathologic parameter with age. EOBC was associated with higher DCIS component (24.8% vs 21.6%), lower hormone-receptor-positive status (52.30% vs 55.70%), higher proliferation index (Ki-67ā€‰\u3eā€‰20: 82.40% vs 80.30%) and a higher number of involved lymph nodes (13.80% vs 9.00%). Triple-Negative Breast cancer (26.40% vs 24.30%) was the most predominant molecular subtype of EOBC. CONCLUSION: EOBCs in our setting are generally more aggressive with poorer prognostic histopathological and molecular features when compared with LOBCs. A larger study is recommended to identify the association between relevant pathological features and early onset breast cancer in Ghana. Again, further molecular and genetic studies to understand the molecular genetic drivers of the general poorer pathological features of EOBCs and its relation to patient outcome in our setting is needed

    Burden of disease scenarios for 204 countries and territories, 2022ā€“2050: a forecasting analysis for the Global Burden of Disease Study 2021

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    Background: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternative scenarios assessing disease burden trajectories if selected sets of risk factors were eliminated from current levels by 2050. Methods: Using forecasts of major drivers of health such as the Socio-demographic Index (SDI; a composite measure of lag-distributed income per capita, mean years of education, and total fertility under 25 years of age) and the full set of risk factor exposures captured by GBD, we provide cause-specific forecasts of mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) by age and sex from 2022 to 2050 for 204 countries and territories, 21 GBD regions, seven super-regions, and the world. All analyses were done at the cause-specific level so that only risk factors deemed causal by the GBD comparative risk assessment influenced future trajectories of mortality for each disease. Cause-specific mortality was modelled using mixed-effects models with SDI and time as the main covariates, and the combined impact of causal risk factors as an offset in the model. At the all-cause mortality level, we captured unexplained variation by modelling residuals with an autoregressive integrated moving average model with drift attenuation. These all-cause forecasts constrained the cause-specific forecasts at successively deeper levels of the GBD cause hierarchy using cascading mortality models, thus ensuring a robust estimate of cause-specific mortality. For non-fatal measures (eg, low back pain), incidence and prevalence were forecasted from mixed-effects models with SDI as the main covariate, and YLDs were computed from the resulting prevalence forecasts and average disability weights from GBD. Alternative future scenarios were constructed by replacing appropriate reference trajectories for risk factors with hypothetical trajectories of gradual elimination of risk factor exposure from current levels to 2050. The scenarios were constructed from various sets of risk factors: environmental risks (Safer Environment scenario), risks associated with communicable, maternal, neonatal, and nutritional diseases (CMNNs; Improved Childhood Nutrition and Vaccination scenario), risks associated with major non-communicable diseases (NCDs; Improved Behavioural and Metabolic Risks scenario), and the combined effects of these three scenarios. Using the Shared Socioeconomic Pathways climate scenarios SSP2-4.5 as reference and SSP1-1.9 as an optimistic alternative in the Safer Environment scenario, we accounted for climate change impact on health by using the most recent Intergovernmental Panel on Climate Change temperature forecasts and published trajectories of ambient air pollution for the same two scenarios. Life expectancy and healthy life expectancy were computed using standard methods. The forecasting framework includes computing the age-sex-specific future population for each location and separately for each scenario. 95% uncertainty intervals (UIs) for each individual future estimate were derived from the 2Ā·5th and 97Ā·5th percentiles of distributions generated from propagating 500 draws through the multistage computational pipeline. Findings: In the reference scenario forecast, global and super-regional life expectancy increased from 2022 to 2050, but improvement was at a slower pace than in the three decades preceding the COVID-19 pandemic (beginning in 2020). Gains in future life expectancy were forecasted to be greatest in super-regions with comparatively low life expectancies (such as sub-Saharan Africa) compared with super-regions with higher life expectancies (such as the high-income super-region), leading to a trend towards convergence in life expectancy across locations between now and 2050. At the super-region level, forecasted healthy life expectancy patterns were similar to those of life expectancies. Forecasts for the reference scenario found that health will improve in the coming decades, with all-cause age-standardised DALY rates decreasing in every GBD super-region. The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. We also forecasted that both DALY counts and age-standardised DALY rates will continue to shift from CMNNs to NCDs, with the most pronounced shifts occurring in sub-Saharan Africa (60Ā·1% [95% UI 56Ā·8ā€“63Ā·1] of DALYs were from CMNNs in 2022 compared with 35Ā·8% [31Ā·0ā€“45Ā·0] in 2050) and south Asia (31Ā·7% [29Ā·2ā€“34Ā·1] to 15Ā·5% [13Ā·7ā€“17Ā·5]). This shift is reflected in the leading global causes of DALYs, with the top four causes in 2050 being ischaemic heart disease, stroke, diabetes, and chronic obstructive pulmonary disease, compared with 2022, with ischaemic heart disease, neonatal disorders, stroke, and lower respiratory infections at the top. The global proportion of DALYs due to YLDs likewise increased from 33Ā·8% (27Ā·4ā€“40Ā·3) to 41Ā·1% (33Ā·9ā€“48Ā·1) from 2022 to 2050, demonstrating an important shift in overall disease burden towards morbidity and away from premature death. The largest shift of this kind was forecasted for sub-Saharan Africa, from 20Ā·1% (15Ā·6ā€“25Ā·3) of DALYs due to YLDs in 2022 to 35Ā·6% (26Ā·5ā€“43Ā·0) in 2050. In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15Ā·4% (13Ā·5ā€“17Ā·5) compared with the reference scenario, with decreases across super-regions ranging from 10Ā·4% (9Ā·7ā€“11Ā·3) in the high-income super-region to 23Ā·9% (20Ā·7ā€“27Ā·3) in north Africa and the Middle East. The Safer Environment scenario had its largest decrease in sub-Saharan Africa (5Ā·2% [3Ā·5ā€“6Ā·8]), the Improved Behavioural and Metabolic Risks scenario in north Africa and the Middle East (23Ā·2% [20Ā·2ā€“26Ā·5]), and the Improved Nutrition and Vaccination scenario in sub-Saharan Africa (2Ā·0% [ā€“0Ā·6 to 3Ā·6]). Interpretation: Globally, life expectancy and age-standardised disease burden were forecasted to improve between 2022 and 2050, with the majority of the burden continuing to shift from CMNNs to NCDs. That said, continued progress on reducing the CMNN disease burden will be dependent on maintaining investment in and policy emphasis on CMNN disease prevention and treatment. Mostly due to growth and ageing of populations, the number of deaths and DALYs due to all causes combined will generally increase. By constructing alternative future scenarios wherein certain risk exposures are eliminated by 2050, we have shown that opportunities exist to substantially improve health outcomes in the future through concerted efforts to prevent exposure to well established risk factors and to expand access to key health interventions

    Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950ā€“2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

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    Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020ā€“21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62Ā·8% [95% UI 60Ā·5ā€“65Ā·1] decline), and increased during the COVID-19 pandemic period (2020ā€“21; 5Ā·1% [0Ā·9ā€“9Ā·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4Ā·66 million (3Ā·98ā€“5Ā·50) global deaths in children younger than 5 years in 2021 compared with 5Ā·21 million (4Ā·50ā€“6Ā·01) in 2019. An estimated 131 million (126ā€“137) people died globally from all causes in 2020 and 2021 combined, of which 15Ā·9 million (14Ā·7ā€“17Ā·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22Ā·7 years (20Ā·8ā€“24Ā·8), from 49Ā·0 years (46Ā·7ā€“51Ā·3) to 71Ā·7 years (70Ā·9ā€“72Ā·5). Global life expectancy at birth declined by 1Ā·6 years (1Ā·0ā€“2Ā·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15Ā·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7Ā·89 billion (7Ā·67ā€“8Ā·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39Ā·5% [28Ā·4ā€“52Ā·7]) and south Asia (26Ā·3% [9Ā·0ā€“44Ā·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92Ā·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic

    The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019

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    Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe

    Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990ā€“2021: a systematic analysis for the Global Burden of Disease Study 2021

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    Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sustainable Development Goals. For three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has filled that need. A global network of collaborators contributed to the production of GBD 2021 by providing, reviewing, and analysing all available data. GBD estimates are updated routinely with additional data and refined analytical methods. GBD 2021 presents, for the first time, estimates of health loss due to the COVID-19 pandemic. Methods: The GBD 2021 disease and injury burden analysis estimated years lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries using 100 983 data sources. Data were extracted from vital registration systems, verbal autopsies, censuses, household surveys, disease-specific registries, health service contact data, and other sources. YLDs were calculated by multiplying cause-age-sex-location-year-specific prevalence of sequelae by their respective disability weights, for each disease and injury. YLLs were calculated by multiplying cause-age-sex-location-year-specific deaths by the standard life expectancy at the age that death occurred. DALYs were calculated by summing YLDs and YLLs. HALE estimates were produced using YLDs per capita and age-specific mortality rates by location, age, sex, year, and cause. 95% uncertainty intervals (UIs) were generated for all final estimates as the 2Ā·5th and 97Ā·5th percentiles values of 500 draws. Uncertainty was propagated at each step of the estimation process. Counts and age-standardised rates were calculated globally, for seven super-regions, 21 regions, 204 countries and territories (including 21 countries with subnational locations), and 811 subnational locations, from 1990 to 2021. Here we report data for 2010 to 2021 to highlight trends in disease burden over the past decade and through the first 2 years of the COVID-19 pandemic. Findings: Global DALYs increased from 2Ā·63 billion (95% UI 2Ā·44ā€“2Ā·85) in 2010 to 2Ā·88 billion (2Ā·64ā€“3Ā·15) in 2021 for all causes combined. Much of this increase in the number of DALYs was due to population growth and ageing, as indicated by a decrease in global age-standardised all-cause DALY rates of 14Ā·2% (95% UI 10Ā·7ā€“17Ā·3) between 2010 and 2019. Notably, however, this decrease in rates reversed during the first 2 years of the COVID-19 pandemic, with increases in global age-standardised all-cause DALY rates since 2019 of 4Ā·1% (1Ā·8ā€“6Ā·3) in 2020 and 7Ā·2% (4Ā·7ā€“10Ā·0) in 2021. In 2021, COVID-19 was the leading cause of DALYs globally (212Ā·0 million [198Ā·0ā€“234Ā·5] DALYs), followed by ischaemic heart disease (188Ā·3 million [176Ā·7ā€“198Ā·3]), neonatal disorders (186Ā·3 million [162Ā·3ā€“214Ā·9]), and stroke (160Ā·4 million [148Ā·0ā€“171Ā·7]). However, notable health gains were seen among other leading communicable, maternal, neonatal, and nutritional (CMNN) diseases. Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47Ā·8% (43Ā·3ā€“51Ā·7) and for diarrhoeal diseases decreased by 47Ā·0% (39Ā·9ā€“52Ā·9). Non-communicable diseases contributed 1Ā·73 billion (95% UI 1Ā·54ā€“1Ā·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6Ā·4% (95% UI 3Ā·5ā€“9Ā·5). Between 2010 and 2021, among the 25 leading Level 3 causes, age-standardised DALY rates increased most substantially for anxiety disorders (16Ā·7% [14Ā·0ā€“19Ā·8]), depressive disorders (16Ā·4% [11Ā·9ā€“21Ā·3]), and diabetes (14Ā·0% [10Ā·0ā€“17Ā·4]). Age-standardised DALY rates due to injuries decreased globally by 24Ā·0% (20Ā·7ā€“27Ā·2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61Ā·3 years (58Ā·6ā€“63Ā·6) in 2010 to 62Ā·2 years (59Ā·4ā€“64Ā·7) in 2021. However, despite this overall increase, HALE decreased by 2Ā·2% (1Ā·6ā€“2Ā·9) between 2019 and 2021. Interpretation: Putting the COVID-19 pandemic in the context of a mutually exclusive and collectively exhaustive list of causes of health loss is crucial to understanding its impact and ensuring that health funding and policy address needs at both local and global levels through cost-effective and evidence-based interventions. A global epidemiological transition remains underway. Our findings suggest that prioritising non-communicable disease prevention and treatment policies, as well as strengthening health systems, continues to be crucially important. The progress on reducing the burden of CMNN diseases must not stall; although global trends are improving, the burden of CMNN diseases remains unacceptably high. Evidence-based interventions will help save the lives of young children and mothers and improve the overall health and economic conditions of societies across the world. Governments and multilateral organisations should prioritise pandemic preparedness planning alongside efforts to reduce the burden of diseases and injuries that will strain resources in the coming decades. Funding: Bill & Melinda Gates Foundation

    TTDCapsNet: Tri Texton-Dense Capsule Network for complex and medical image recognition.

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    Convolutional Neural Networks (CNNs) are frequently used algorithms because of their propensity to learn relevant and hierarchical features through their feature extraction technique. However, the availability of enormous volumes of data in various variations is crucial for their performance. Capsule networks (CapsNets) perform well on a small amount of data but perform poorly on complex images. To address this, we proposed a new Capsule Network architecture called Tri Texton-Dense CapsNet (TTDCapsNet) for better complex and medical image classification. The TTDCapsNet is made up of three hierarchic blocks of Texton-Dense CapsNet (TDCapsNet) models. A single TDCapsNet is a CapsNet architecture composed of a texton detection layer to extract essential features, which are passed onto an eight-layered block of dense convolution that further extracts features, and then the output feature map is given as input to a Primary Capsule (PC), and then to a Class Capsule (CC) layer for classification. The resulting feature map from the first PC serves as input into the second-level TDCapsNet, and that from the second PC serves as input into the third-level TDCapsNet. The routing algorithm receives feature maps from each PC for the various CCs. Routing the concatenation of the three PCs creates an additional CC layer. All these four feature maps combined, help to achieve better classification. On fashion-MNIST, CIFAR-10, Breast Cancer, and Brain Tumor datasets, the proposed model is evaluated and achieved validation accuracies of 94.90%, 89.09%, 95.01%, and 97.71% respectively. Findings from this work indicate that TTDCapsNet outperforms the baseline and performs comparatively well with the state-of-the-art CapsNet models using different performance metrics. This work clarifies the viability of using Capsule Network on complex tasks in the real world. Thus, the proposed model can be used as an intelligent system, to help oncologists in diagnosing cancerous diseases and administering treatment required

    A Stratification and Sampling Model for Bellwether Moving Window

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    An effective method for finding the relevant number (window size) and the elapsed time (window age) of recently completed projects has proven elusive in software effort estimation. Although these two parameters significantly affect the prediction accuracy, there is no effective method to stratify and sample chronological projects to improve prediction performance of software effort estimation models. Exemplary projects (Bellwether) representing the training set have been empirically validated to improve the prediction accuracy in the domain of software defect prediction. However, the concept of Bellwether and its effect have not been empirically proven in software effort estimation as a method of selecting exemplary/relevant projects with defined window size and age. In view of this, we introduce a novel method for selecting relevant and recently completed projects referred to as Bellwether moving window for improving the software effort prediction accuracy. We first sort and cluster a pool of N projects and apply statistical stratification based on Markov chain modeling to select the Bellwether moving window. We evaluate the proposed approach using the baseline Automatically Transformed Linear Model on the ISBSG dataset. Results show that (1) Bellwether effect exist in software effort estimation dataset, (2) the Bellwether moving window with a window size of 82 to 84 projects and window age of 1.5 to 2 years resulted in an improved prediction accuracy than the traditional approach
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