Retornos accionarios e informacion contable : un caso para el estudio de eventos. Analisis empirico: 4° trimestre periodo 1995-2004

85 p.El impacto que ha tenido la publicación de las Fichas Estadísticas Codificadas Uniformes (FECUs), es decir, la información contable sobre la riqueza de los accionistas chilenos, es un tema que escasamente ha sido discutido por la literatura especializada. La presente investigación, aplica la metodología de Estudio de Eventos para analizar como el mercado de capitales chileno ha incorporado la publicación de las FECUs. Utilizando tres modelos estadísticos, los resultados señalan que Ios precios incorporan en forma positiva y estadísticamente significativa la publicación de buenas noticias contables. En el caso de las malas noticias contables, los precios incorporan en forma negativa y estadísticamente significativa la publicación de estas malas noticias

Molecular Dynamics Simulation of Solvent-Polymer Interdiffusion. I. Fickian diffusion

The interdiffusion of a solvent into a polymer melt has been studied using large scale molecular dynamics and Monte Carlo simulation techniques. The solvent concentration profile and weight gain by the polymer have been measured as a function of time. The weight gain is found to scale as t^{1/2}, which is expected for Fickian type of diffusion. The concentration profiles are fit very well assuming Fick's second law with a constant diffusivity. The diffusivity found from fitting Fick's second law is found to be independent of time and equal to the self diffusion constant in the dilute solvent limit. We separately calculated the diffusivity as a function of concentration using the Darken equation and found that the diffusivity is essentially constant for the concentration range relevant for interdiffusion.Comment: 17 pages and 7 figure

Dynamic screening of a localized hole during photoemission from a metal cluster

Recent advances in attosecond spectroscopy techniques have fueled the interest in the theoretical description of electronic processes taking place in the subfemtosecond time scale. Here we study the coupled dynamic screening of a localized hole and a photoelectron emitted from a metal cluster using a semi-classical model. Electron density dynamics in the cluster is calculated with Time-Dependent Density Functional Theory and the motion of the photoemitted electron is described classically. We show that the dynamic screening of the hole by the cluster electrons affects the motion of the photoemitted electron. At the very beginning of its trajectory, the photoemitted electron interacts with the cluster electrons that pile up to screen the hole. Within our model, this gives rise to a significant reduction of the energy lost by the photoelectron. Thus, this is a velocity dependent effect that should be accounted for when calculating the average losses suffered by photoemitted electrons in metals.Comment: 15 pages, 5 figure

The in-plane electrodynamics of the superconductivity in Bi2Sr2CaCu2O8+d: energy scales and spectral weight distribution

The in-plane infrared and visible (3 meV-3 eV) reflectivity of Bi2Sr2CaCu2O8+d (Bi-2212) thin films is measured between 300 K and 10 K for different doping levels with unprecedented accuracy. The optical conductivity is derived through an accurate fitting procedure. We study the transfer of spectral weight from finite energy into the superfluid as the system becomes superconducting. In the over-doped regime, the superfluid develops at the expense of states lying below 60 meV, a conventional energy of the order of a few times the superconducting gap. In the underdoped regime, spectral weight is removed from up to 2 eV, far beyond any conventional scale. The intraband spectral weight change between the normal and superconducting state, if analyzed in terms of a change of kinetic energy is ~1 meV. Compared to the condensation energy, this figure addresses the issue of a kinetic energy driven mechanism.Comment: 13 pages with 9 figures include

Photometry using the Infrared Array Camera on the Spitzer Space Telescope

We present several corrections for point source photometry to be applied to data from the Infrared Array Camera (IRAC) on the Spitzer Space Telescope. These corrections are necessary because of characteristics of the IRAC arrays and optics and the way the instrument is calibrated in-flight. When these corrections are applied, it is possible to achieve a ~2% relative photometric accuracy for sources of adequate signal to noise in an IRAC image.Comment: 16 pages, 13 figures. Accepted for publication in the Publications of the Astronomical Society of the Pacifi

Hospital doctors' views and concerns about pharmacovigilance

Purpose: The aim of the study was to evaluate the opinions and concerns of hospital doctors about adverse drug reactions (ADRs) and pharmacovigilance. Methods: A qualitative study was undertaken using focus groups in sessions on pharmacovigilance activities conducted in thirteen clinical services of a tertiary university hospital. A total of 296 physicians participated in these sessions by giving their opinions or expressing their doubts about ADR and pharmacovigilance activities which were recorded by different observers and subsequently analysed. Results: Doctors remarked on: a) the importance, concern, frequency and specific types of ADRs that were observed in clinical practice; b) problems of clinical decision making related to the suspected ADRs; c) methods for improving detection and reporting ADRs; d) monitoring of specific ADRs or ADRs caused by specific drugs; e) and measures to prevent and minimize the risk of ADRs. Physicians expressed doubts related to: a) the basic concepts of ADRs; b) the methods of ADR identification and evaluation; c) the objectives and procedures of pharmacovigilance programmes; d) and the impact of pharmacovigilance activities. Conclusions: Hospital doctors believe that ADRs are a matter for concern in their daily clinical practice, and monitoring ADRs as well as measures for preventing the risk of ADRs are needed. Nevertheless, doctors have doubts about what an ADR is, the accuracy of diagnostic methods, the development of pharmacovigilance activities and their impact on clinical practice. Pharmacovigilance should be better explained through a continuous feedback and close relationship with hospital doctors

Charge Ordering Fluctuation and Optical Pseudogap in La1−x_{1-x}Cax_{x}MnO3_{3}

Optical spectroscopy was used to investigate the optical gap (2$\Delta$) due to charge ordering (CO) and related pseudogap developments with x and temperature (T) in La$_{1-x}$Ca$_{x}$MnO$_{3}$ (0.48 <= x <= 0.67). Surprisingly, we found 2$\Delta$/k_{B}T_{CO} is as large as 30 for x ~0.5, and decreases rapidly with increasing x. Simultaneously, the optical pseudogap, possibly starting from T^* far above T_{CO} becomes drastically enhanced near x=0.5, producing non-BCS T-dependence of 2$\Delta$ with the large magnitude far above T_{CO}, and systematic increase of T^* for x~0.5. These results unequivocally indicate systematically-enhanced CO correlation when x approaches 0.5 even though T_{CO} decreases.Comment: 5 pages, 4 figures embedded, submitted to Phys. Rev. Let

Optical conductivity in doped manganites with planar x2^2-y2^2 orbital order

We investigate a planar model for the ferromagnetic (FM) phase of manganites, which develops orbital order of $e_g$ electrons with x$^2$-y$^2$-symmetry at low temperature. The dynamic structure factor of orbital excitations and the optical conductivity $\sigma(\omega)$ are studied with help of a finite-temperature diagonalization method. Our calculations provide a theoretical prediction for $\sigma(\omega)$ for the 2D FM state and are of possible relevance for the recently found A-type phase of manganites at high doping which consists of FM layers coupled antiferromagnetically. In the x$^2$-y$^2$ ordered regime $\sigma(\omega)$ shows both a Drude peak and a gapped incoherent absorption due to a gap in the orbital excitations.Comment: 5 pages, 5 figures, to appear in Phys. Rev. Let

Metal-induced malformations in early Palaeozoic plankton are harbingers of mass extinction

Glacial episodes have been linked to Ordovician–Silurian extinction events, but cooling itself may not be solely responsible for these extinctions. Teratological (malformed) assemblages of fossil plankton that correlate precisely with the extinction events can help identify alternate drivers of extinction. Here we show that metal poisoning may have caused these aberrant morphologies during a late Silurian (Pridoli) event. Malformations coincide with a dramatic increase of metals (Fe, Mo, Pb, Mn and As) in the fossils and their host rocks. Metallic toxins are known to cause a teratological response in modern organisms, which is now routinely used as a proxy to assess oceanic metal contamination. Similarly, our study identifies metal-induced teratology as a deep-time, palaeobiological monitor of palaeo-ocean chemistry. The redox-sensitive character of enriched metals supports emerging ‘oceanic anoxic event’ models. Our data suggest that spreading anoxia and redox cycling of harmful metals was a contributing kill mechanism during these devastating Ordovician–Silurian palaeobiological events

Deletion of low molecular weight protein tyrosine phosphatase (Acp1) protects against stress-induced cardiomyopathy.

The low molecular weight protein tyrosine phosphatase (LMPTP), encoded by the ACP1 gene, is a ubiquitously expressed phosphatase whose in vivo function in the heart and in cardiac diseases remains unknown. To investigate the in vivo role of LMPTP in cardiac function, we generated mice with genetic inactivation of the Acp1 locus and studied their response to long-term pressure overload. Acp1(-/-) mice develop normally and ageing mice do not show pathology in major tissues under basal conditions. However, Acp1(-/-) mice are strikingly resistant to pressure overload hypertrophy and heart failure. Lmptp expression is high in the embryonic mouse heart, decreased in the postnatal stage, and increased in the adult mouse failing heart. We also show that LMPTP expression increases in end-stage heart failure in humans. Consistent with their protected phenotype, Acp1(-/-) mice subjected to pressure overload hypertrophy have attenuated fibrosis and decreased expression of fibrotic genes. Transcriptional profiling and analysis of molecular signalling show that the resistance of Acp1(-/-) mice to pathological cardiac stress correlates with marginal re-expression of fetal cardiac genes, increased insulin receptor beta phosphorylation, as well as PKA and ephrin receptor expression, and inactivation of the CaMKIIδ pathway. Our data show that ablation of Lmptp inhibits pathological cardiac remodelling and suggest that inhibition of LMPTP may be of therapeutic relevance for the treatment of human heart failure