14 research outputs found

    Estudio de la infraestructura de mediciĂłn avanzada(AMI), principales requerimientos y beneficios

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    This work investigated the AMI technology - Advanced Metering Infrastructure, its main components, requirements and benefits. This document is a proposal that allow the execution of feasibility studies of AMI technology projects that will be implemented in electricity distribution companies. Nowadays there is a growing emphasis on improving the energy markets efficiency, optimizing the supply’s security and the correct use of energy saving benefits. One of the electricity company’s problems is the lack of standards, as response, the CIM-Common Information Model" has been designed. The CIM offers a new perspective "object oriented" for distributed resources. Through this representation as "objects", the way that a resource is described is generic. What is characteristic for each resource is the value of the attributes that has. This model is described in the IEC 61970 and IEC 61968, which is explained in this project, mainly the Standard Interface for monitoring and meter reading (MR) IEC 61968-9. Furthermore, this paper argues that the tendency to implement standards such as IEC 61970/61968 involves the use of UML-Unified Modeling Language. In addition, the analysis performed provides an overview of new measurement technologies through the examination of international trends and various components of AMI systems. Then the impact of costs - benefits of the smart metering and distribution system will be study in order to determinate the economic risk. After, we will study the conditions in Europe, North America and Australia, and determinate how countries and regions have variances in their approaches and how these differences have had an impact on their policy. In fact, in our country there are many electricity power distribution companies that suffer losses in the electrical power delivered area, because of unaffected control component’s, the resulted: the total energy input which is purchased to the generators is different to the total energy charged to the customers. An analysis cost- benefit for a pilot project is been done in two electricity power distribution inside the country.AMI es un importante avance tecnolĂłgico para incorporar a los consumidores medidores electrĂłnicos capaces de obtener mediciones de energĂ­a de una forma mĂĄs precisa, eficiente y, obtener informaciĂłn del consumo de energĂ­a elĂ©ctrica en tiempo real y ser transmitido atreves de un sistema de comunicaciĂłn a las Empresas Distribuidoras al mismo tiempo, proporcionarĂĄ a las Empresas de DistribuciĂłn la capacidad de detectar problemas en sus sistemas y gestionar la demanda, con el fin de operar mĂĄs eficientemente

    Canagliflozin and renal outcomes in type 2 diabetes and nephropathy

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    BACKGROUND Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium–glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS In this double-blind, randomized trial, we assigned patients with type 2 diabetes and albuminuric chronic kidney disease to receive canagliflozin, an oral SGLT2 inhibitor, at a dose of 100 mg daily or placebo. All the patients had an estimated glomerular filtration rate (GFR) of 30 to <90 ml per minute per 1.73 m2 of body-surface area and albuminuria (ratio of albumin [mg] to creatinine [g], >300 to 5000) and were treated with renin–angiotensin system blockade. The primary outcome was a composite of end-stage kidney disease (dialysis, transplantation, or a sustained estimated GFR of <15 ml per minute per 1.73 m2), a doubling of the serum creatinine level, or death from renal or cardiovascular causes. Prespecified secondary outcomes were tested hierarchically. RESULTS The trial was stopped early after a planned interim analysis on the recommendation of the data and safety monitoring committee. At that time, 4401 patients had undergone randomization, with a median follow-up of 2.62 years. The relative risk of the primary outcome was 30% lower in the canagliflozin group than in the placebo group, with event rates of 43.2 and 61.2 per 1000 patient-years, respectively (hazard ratio, 0.70; 95% confidence interval [CI], 0.59 to 0.82; P=0.00001). The relative risk of the renal-specific composite of end-stage kidney disease, a doubling of the creatinine level, or death from renal causes was lower by 34% (hazard ratio, 0.66; 95% CI, 0.53 to 0.81; P<0.001), and the relative risk of end-stage kidney disease was lower by 32% (hazard ratio, 0.68; 95% CI, 0.54 to 0.86; P=0.002). The canagliflozin group also had a lower risk of cardiovascular death, myocardial infarction, or stroke (hazard ratio, 0.80; 95% CI, 0.67 to 0.95; P=0.01) and hospitalization for heart failure (hazard ratio, 0.61; 95% CI, 0.47 to 0.80; P<0.001). There were no significant differences in rates of amputation or fracture. CONCLUSIONS In patients with type 2 diabetes and kidney disease, the risk of kidney failure and cardiovascular events was lower in the canagliflozin group than in the placebo group at a median follow-up of 2.62 years

    GestiĂłn del conocimiento. Perspectiva multidisciplinaria. Volumen 17

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    El libro “GestiĂłn del Conocimiento. Perspectiva Multidisciplinaria”, Volumen 17 de la ColecciĂłn UniĂłn Global, es resultado de investigaciones. Los capĂ­tulos del libro, son resultados de investigaciones desarrolladas por sus autores. El libro es una publicaciĂłn internacional, seriada, continua, arbitrada, de acceso abierto a todas las ĂĄreas del conocimiento, orientada a contribuir con procesos de gestiĂłn del conocimiento cientĂ­fico, tecnolĂłgico y humanĂ­stico. Con esta colecciĂłn, se aspira contribuir con el cultivo, la comprensiĂłn, la recopilaciĂłn y la apropiaciĂłn social del conocimiento en cuanto a patrimonio intangible de la humanidad, con el propĂłsito de hacer aportes con la transformaciĂłn de las relaciones socioculturales que sustentan la construcciĂłn social de los saberes y su reconocimiento como bien pĂșblico

    Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

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    Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

    Fundamentos para el cĂĄlculo - MA384 201801

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    Descripción: El curso de Fundamentos para el Cålculo es un curso teórico - pråctico, dictado en modalidad Blended, dirigido a los estudiantes de Administración del primer ciclo y que trabaja en las primeras unidades los temas de ecuaciones, inecuaciones y gråficas en el plano, para poder acometer el estudio de las funciones en la unidad 3, y usarlas para resolver problemas de aplicación con contexto real. Las clases se imparten en 3 sesiones semanales, las dos primeras son presenciales y la tercera es online. Propósito: El curso estå diseñado para desarrollar en los estudiantes la competencia de Razonamiento Cuantitativo, a nivel 1, por medio del estudio de situaciones problemåticas a las que, de ahora en adelante nos referiremos como casos, cuyo dominio les ayudarå a desenvolverse con éxito en situaciones que involucran el pensamiento matemåtico para la toma de decisiones

    Revista Temas Agrarios Volumen 26; Suplemento 1 de 2021

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    1st International and 2nd National Symposium of Agronomic Sciences: The rebirth of the scientific discussion space for the Colombian Agro.1 Simposio Intenacional y 2 Nacional de Ciencias AgronĂłmicas: El renacer del espacio de discusiĂłn cientĂ­fica para el Agro colombiano

    Evolution over Time of Ventilatory Management and Outcome of Patients with Neurologic Disease∗

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    OBJECTIVES: To describe the changes in ventilator management over time in patients with neurologic disease at ICU admission and to estimate factors associated with 28-day hospital mortality. DESIGN: Secondary analysis of three prospective, observational, multicenter studies. SETTING: Cohort studies conducted in 2004, 2010, and 2016. PATIENTS: Adult patients who received mechanical ventilation for more than 12 hours. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Among the 20,929 patients enrolled, we included 4,152 (20%) mechanically ventilated patients due to different neurologic diseases. Hemorrhagic stroke and brain trauma were the most common pathologies associated with the need for mechanical ventilation. Although volume-cycled ventilation remained the preferred ventilation mode, there was a significant (p < 0.001) increment in the use of pressure support ventilation. The proportion of patients receiving a protective lung ventilation strategy was increased over time: 47% in 2004, 63% in 2010, and 65% in 2016 (p < 0.001), as well as the duration of protective ventilation strategies: 406 days per 1,000 mechanical ventilation days in 2004, 523 days per 1,000 mechanical ventilation days in 2010, and 585 days per 1,000 mechanical ventilation days in 2016 (p < 0.001). There were no differences in the length of stay in the ICU, mortality in the ICU, and mortality in hospital from 2004 to 2016. Independent risk factors for 28-day mortality were age greater than 75 years, Simplified Acute Physiology Score II greater than 50, the occurrence of organ dysfunction within first 48 hours after brain injury, and specific neurologic diseases such as hemorrhagic stroke, ischemic stroke, and brain trauma. CONCLUSIONS: More lung-protective ventilatory strategies have been implemented over years in neurologic patients with no effect on pulmonary complications or on survival. We found several prognostic factors on mortality such as advanced age, the severity of the disease, organ dysfunctions, and the etiology of neurologic disease
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