46 research outputs found

    Cell-based tissue engineering strategies used in the clinical repair of articular cartilage

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    One of the most important issues facing cartilage tissue engineering is the inability to move technologies into the clinic. Despite the multitude of review articles on the paradigm of biomaterials, signals, and cells, it is reported that 90% of new drugs that advance past animal studies fail clinical trials (1). The intent of this review is to provide readers with an understanding of the scientific details of tissue engineered cartilage products that have demonstrated a certain level of efficacy in humans, so that newer technologies may be developed upon this foundation. Compared to existing treatments, such as microfracture or autologous chondrocyte implantation, a tissue engineered product can potentially provide more consistent clinical results in forming hyaline repair tissue and in filling the entirety of the defect. The various tissue engineering strategies (e.g., cell expansion, scaffold material, media formulations, biomimetic stimuli, etc.) used in forming these products, as collected from published literature, company websites, and relevant patents, are critically discussed. The authors note that many details about these products remain proprietary, not all information is made public, and that advancements to the products are continuously made. Nevertheless, by fully understanding the design and production processes of these emerging technologies, one can gain tremendous insight into how to best use them and also how to design the next generation of tissue engineered cartilage products

    Faust. Till Eulenspiegel. Der ewige Jude. Wilhelm Tell

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    FAUST. TILL EULENSPIEGEL. DER EWIGE JUDE. WILHELM TELL Deutsche Sagen in ihrer Entstehung, Fortbildung und poetischen Gestaltung / von Jakob Nover (-) Faust. Till Eulenspiegel. Der ewige Jude. Wilhelm Tell (Bd. 1 = [1], Bd. 1) (1) Einband (1) Titelseite (5) Widmung (7) Vorwort (9) Illustration (Faust Radierung) (12) Faust (13) 1. Hat es einen Dr. Faust gegeben? (15) 2. Die Volksbücher von Faust und das Wesen der mittelalterlichen ... (52) 3. Die Faustlitteratur (Marlowe, Puppenspiele) (74) 4. Lessing, Chamisso, Lenau, Grabbe. (86) 5. Goethes Faust (107) 6. Fortsetzungen und Ergänzungen des Goethe'schen Faust. (117) 7. Schriften über Goethes Faust. (136) Nachtrag. (157) Illustration (Till Eulenspiegel) (160) Till Eulenspiegel (161) Illustration (224) Die Sage vom ewigen Juden (225) Illustration (314) Wilhelm Tell (315

    Deutsche Sagen in ihrer Entstehung, Fortbildung und poetischen Gestaltung / von Jakob Nover

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    DEUTSCHE SAGEN IN IHRER ENTSTEHUNG, FORTBILDUNG UND POETISCHEN GESTALTUNG / VON JAKOB NOVER Deutsche Sagen in ihrer Entstehung, Fortbildung und poetischen Gestaltung / von Jakob Nover Faust. Till Eulenspiegel. Der ewige Jude. Wilhelm Tell (Bd. 1 = [1], Bd. 1

    Das alte und neue Worms in Schrift und Bild

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    von J. Nover. Mit zwei Kunstbeilagen von Peter Becke

    Die Thiersage

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    von Jakob Nove

    Die Lohengrinsage und ihre poetische Gestaltung

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    von J. NoverIn Fraktu

    Die Tannhäusersage und ihre poetische Gestaltung

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    von Jakob NoverIn Fraktu

    Koblenz und die Rheinfahrt von Mainz bis Köln und Düsseldorf

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    von Jakob Nove
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