45 research outputs found

    Fault Detection using Dynamic Parity Space Approach

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    This paper review the effectiveness of the parity space approach to identify faults or disturbance in a system. The most commonly used is the observer based procedures, and redundancy relationship method. This involves analytical mathematical analysis of geometry and bilinear algebra. Then, technological advances which require complex computation such as artificial intelligence and genetic algorithm had made tremendous improvement to fault Detection and Isolation (FDI) analysis. Dynamic Parity Space Approach was studied for a discrete state-space model. Important data will be extracted using this approach especially for residual generation which is the backbones of FDI analysis. Subsequently, at each time instant k, the generated residuals will form a matrix that will define the fault signature. It is remarkable that this approach is proven in this study to be effective in diagnosis and faults isolation

    Cause of Death and Predictors of All-Cause Mortality in Anticoagulated Patients With Nonvalvular Atrial Fibrillation : Data From ROCKET AF

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    M. Kaste on työryhmän ROCKET AF Steering Comm jäsen.Background-Atrial fibrillation is associated with higher mortality. Identification of causes of death and contemporary risk factors for all-cause mortality may guide interventions. Methods and Results-In the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation (ROCKET AF) study, patients with nonvalvular atrial fibrillation were randomized to rivaroxaban or dose-adjusted warfarin. Cox proportional hazards regression with backward elimination identified factors at randomization that were independently associated with all-cause mortality in the 14 171 participants in the intention-to-treat population. The median age was 73 years, and the mean CHADS(2) score was 3.5. Over 1.9 years of median follow-up, 1214 (8.6%) patients died. Kaplan-Meier mortality rates were 4.2% at 1 year and 8.9% at 2 years. The majority of classified deaths (1081) were cardiovascular (72%), whereas only 6% were nonhemorrhagic stroke or systemic embolism. No significant difference in all-cause mortality was observed between the rivaroxaban and warfarin arms (P=0.15). Heart failure (hazard ratio 1.51, 95% CI 1.33-1.70, P= 75 years (hazard ratio 1.69, 95% CI 1.51-1.90, P Conclusions-In a large population of patients anticoagulated for nonvalvular atrial fibrillation, approximate to 7 in 10 deaths were cardiovascular, whereasPeer reviewe

    Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015)

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    Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

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    Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

    Development of framework for armoured vehicle assembly line efficiency improvement by using simulation analysis: Part 1

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    Efficiencies and the productivity of the assembly line are crucial in the manufacturing sector. It is very unusual opportunity to visualise and analyse the production system, which used in defence manufacturing sector. This research study focuses on the performance of an existing production line for Malaysia's automotive defence manufacturing industry. The main issues that arise are first, the delivery is always behind the schedule and second, the human factor that contributes to the increase of rejected parts and slow down the production line. WITNESS simulation will be utilised to analyse the dynamic issues associated with the whole performance of the manufacturing system. A methodology for production layout improvement will bring into notice. DELMIA simulation can improve employee's working condition, which is to optimise the production line efficiency. The assembly line can be better in many ways, for example, the arrangement of working layout, the summit of the workplace and massive machines handling method by the worker. All of these are imperative to increase the efficiency of the employees. Continuous improvement of the proposed methodology includes progress in model design, training of operators, follow-up of implementing changes and investigations in the measurement of manufacturing line efficiencies
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