2,005 research outputs found

    Bio-resources for sharing: which communities and what specific needs

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    Biobanks are an important source to obtain samples and data for research purposes for a wide array of communities. In fact, sharing of bio-resources and data is an integral part of a biobank's role. For an effective partnership a list of requirements or needs have to be met, assuring quality of the resources shared as well as quality of the collaboration in general. Tracking and documenting bio-resource sharing and collaborations of a biobank can be seen as one indicator of the "impact" a biobank has to the field. As an example, the practice of the Estonian Genome Center of the University of Tartu is presented

    Planeerija muutuv roll. Loov pragmatism Eesti ruumilises planeerimises

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    Väitekirja elektrooniline versioon ei sisalda publikatsiooneDoktoritöö eesmärgiks on portreteerida Eesti ruumilise planeerimise teoreetilist kontseptsiooni, uurides muutusi planeerija rollis. Ma vaatlen planeerijate ülesandeid, otsustusõigust ja võimu, samuti professionaalseid oskusi. Eesti ruumilise planeerimise teoreetilise raamistikuna pakun välja loova pragmatismi, mis aitab mõista planeerijatele esitatavate ootuste laiemat konteksti. Analüüsin planeerija rolli ja pragmatismi ilminguid Kesk- ja Ida-Euroopale ning Eestile iseloomulike ruumiliste nähtuste, suvilaalade ja paneelelamurajoonide, näitel. Sotsialistliku ruumiplaneerimise ehedate näidetena peegeldub nende alade arenguloos meie sotsiaal-kultuuriline pärandit. Sealsete eripäraste elukeskkondade kujunemislugu aitab avada planeerija rolli erinevatel tasanditel.The aim of this research is to establish a theoretical concept for spatial planning in Estonia and examine the role of planners in the society. I concentrate on summer house settlements - “summurbia” - and large socialist housing estates which are two characteristic spatial phenomena specific to the Central and Eastern Europe and Estonia. As vivid examples of the legacy of socialist spatial planning, these areas reflect clearly the socio-cultural background of the Soviet Era and are thus uniquely suitable objects for studying planning theory and practice. The evolution of these distinct living environments exposes the role of a planner on multiple levels. I study the tasks assigned to planners and the powers seized by them, the opportunities they sought and skills they needed in their professional activities. I propose pragmatism as the theoretical framework underlying Estonian planning and explore the wider context of expectations for planners.https://www.ester.ee/record=b5250529~S

    Eesti geenivaramust personaalse meditsiinini –20 aastat!

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    Eesti Arst 2021; 100(5):280–286 &nbsp

    Personality Traits and Eating Habits in a Large Sample of Estonians

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    Locations of several novel 2'-O-methylated nucleotides in human 28S rRNA

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    BACKGROUND: Ribose 2'-O-methylation, the most common nucleotide modification in mammalian rRNA, is directed by the C/D box small nucleolar RNAs (snoRNAs). Thus far, more than fifty putative human rRNA methylation guide snoRNAs have been identified. For nine of these snoRNAs, the respective ribose methylations in human 28S rRNA have been only presumptive. RESULTS: In this study, the methylation state of human 28S rRNA in the positions predicted by the snoRNAs U21, U26, U31, U48, U50, U73, U74, U80 and U81 was assessed using reverse transcription-based methods and several novel 2'-O-methylations were localized. CONCLUSIONS: Seven novel ribose 2'-O-methylated residues (Am389, Am391, Gm1604, Gm1739, Gm2853, Cm3810, Gm4156, predicted by snoRNAs U26, U81, U80, U73, U50, U74 and U31, respectively) have been localized in human 28S rRNA. The total number of 2'-O-methylations in human rRNA is not yet known

    Legal Fiction

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    While numerous ancient human DNA datasets from across Europe have been published till date, modern-day Poland in particular, remains uninvestigated. Besides application in the reconstruction of continent-wide human history, data from this region would also contribute towards our understanding of the history of the Slavs, whose origin is hypothesized to be in East or Central Europe. Here, we present the first population-scale ancient human DNA study from the region of modern-day Poland by establishing mitochondrial DNA profiles for 23 samples dated to 200 BC - 500 AD (Roman Iron Age) and for 20 samples dated to 1000-1400 AD (Medieval Age). Our results show that mitochondrial DNA sequences from both periods belong to haplogroups that are characteristic of contemporary West Eurasia. Haplotype sharing analysis indicates that majority of the ancient haplotypes are widespread in some modern Europeans, including Poles. Notably, the Roman Iron Age samples share more rare haplotypes with Central and Northeast Europeans, whereas the Medieval Age samples share more rare haplotypes with East-Central and South-East Europeans, primarily Slavic populations. Our data demonstrates genetic continuity of certain matrilineages (H5a1 and N1a1a2) in the area of present-day Poland from at least the Roman Iron Age until present. As such, the maternal gene pool of present-day Poles, Czechs and Slovaks, categorized as Western Slavs, is likely to have descended from inhabitants of East-Central Europe during the Roman Iron Age

    Key pests and their parasitoids on spring and winter oilseed rape in Estonia

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    The pests and their hymenopterous parasitoids present in a spring and a winter oilseed rape crop in Estoniawere studied. Meligethes aeneus was themost abundant pest in both crops. Other crucifer-specialist pests included: Ceutorhynchus assimilis, C. pallidactylus, C. rapae, C. floralis, C. pleurostigma and Phyllotreta spp., but their abundance was low. Four species of parasitoids of M. aeneus larvae (Diospilus capito, Phradis morionellus, P. interstitialis and Tersilochus heterocerus) and threeof C. assimilis larvae (Mesopolobus morys, Stenomalina gracilis and Trichomalus perfectus) were also found

    Süsiniknanotorude funktsionaliseerimine ning radiomarkeerimine Ra-226 aatomitega

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    http://tartu.ester.ee/record=b2653907~S1*es

    MtDNA profile of West Africa Guineans: towards a better understanding of the Senegambia region

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    The matrilineal genetic composition of 372 samples from the Republic of Guiné-Bissau (West African coast) was studied using RFLPs and partial sequencing of the mtDNA control and coding region. The majority of the mtDNA lineages of Guineans (94%) belong to West African specific sub-clusters of L0-L3 haplogroups. A new L3 sub-cluster (L3h) that is found in both eastern and western Africa is present at moderately low frequencies in Guinean populations. A non-random distribution of haplogroups U5 in the Fula group, the U6 among the "Brame" linguistic family and M1 in the Balanta-Djola group, suggests a correlation between the genetic and linguistic affiliation of Guinean populations. The presence of M1 in Balanta populations supports the earlier suggestion of their Sudanese origin. Haplogroups U5 and U6, on the other hand, were found to be restricted to populations that are thought to represent the descendants of a southern expansion of Berbers. Particular haplotypes, found almost exclusively in East-African populations, were found in some ethnic groups with an oral tradition claiming Sudanese origin.info:eu-repo/semantics/publishedVersio
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