506 research outputs found
Development of a gluten free bread enriched with faba bean husk as a fibre supplement
Faba bean husks (FBH) are a high-fibre waste product of faba beans and are primarily used as animal feed with the potential of becoming a fibre supplement. In this study, different levels and particle sizes of FBH flour were used to enhance the fibre content of gluten free bread. Bread properties were evaluated by measuring specific volume, colour (crust and crumb), and crumb texture. The sensory characteristics of breads were assessed by a group of untrained panellists (n = 66) on appearance, aroma, flavour, texture, aftertaste, willingness to buy, and overall acceptability using a nine-point hedonic scale. Volume of bread was affected by the level and particle size of FBH added. Texture analysis showed the importance of level of FBH, and of its particle size in establishing hardness, gumminess, and chewiness (p < 0.05). The added FBH influenced the colour of the crust and crumb. Two formulations of FBH-enriched gluten free bread (particle sizes of 212–300 μm at 5% wheat flour weight substitution, and particle sizes of smaller than 212 μm at 15% wheat four weight substitution) increased the fibre content of the bread, while had no negative impact on sensory evaluation in comparison to control treatment (p < 0.05).</p
Patrones de prescripción de hipolipemiantes en pacientes de Colombia
Introduction. Lipid-lowering drugs, especially statins, have shown great relevance in preventing and treating cardiovascular diseases.Objective. To determine the prescription patterns of lipid-lowering drugs and the variables associated with their use in a Colombian population.Materials and methods. This is a cross-sectional descriptive study. From a drug dispensing database of approximately 4.5 million Colombian health system affiliates, patients of all ages and both sexes treated with lipid-lowering agents (statins, fibrates, ezetimibe) were identified between January and March, 2017. Demographic, pharmacological and co-medication variables were included.Results. In total, 103,624 patients were identified as being treated with lipid-lowering agents. The average age was 67.5 years, and 49.8% were 65 years or older. Women comprised 58.0% of the patients. Statins were the most used (n=96,910; 93.5%), and atorvastatin (n=80,812; 78.0%) and lovastatin (n=12,621; 12.2%) were the most frequent. The mean atorvastatin dose was 30.3 mg/day, and 49.9% of its users received presentations of 40 mg or more. A total of 9,258 (8.9%) patients received fibrates, and only 780 (0.8%) were taking ezetimibe. Of this population, 94.9% were treated with lipid-lowering monotherapy, and 97.3% (n=100,813) had co-medication for their comorbidities, with the most frequent being antihypertensive (89.1%), antiplatelet (57.8%), antidiabetic (31.5%) and antiulcerative agents (34.2%).Conclusions. Atorvastatin is currently the most frequently used lipid-lowering drug in this group of Colombian patients, especially in monotherapy and at doses close to the defined daily dose. Only half received high-intensity doses. New studies are required to verify the efficacy of these therapies.Introducción. Los fármacos hipolipemiantes, especialmente las estatinas, han demostrado gran relevancia para la prevención y el tratamiento de las enfermedades cardiovasculares.Objetivo. Determinar los patrones de prescripción de los fármacos hipolipemiantes y las variables asociadas con su uso en una población de Colombia.Materiales y métodos. Se trata de un estudio descriptivo y transversal. A partir de una base de datos de dispensación de medicamentos de 4,5 millones de afiliados al sistema de salud de Colombia, se identificaron los pacientes de cualquier edad y sexo en tratamiento con hipolipemiantes (estatinas, fibratos, ezetimibe), entre enero y marzo de 2017. Se incluyeron variables demográficas, farmacológicas y de comedicaciones. Resultados. Se identificaron 103.624 pacientes en tratamiento con hipolipemiantes. La edad promedio fue de 67,5 años y el 49,8 % tenía 65 o más años. El 58,0 % eran mujeres. Las estatinas fueron los más utilizados (n=96.910; 93,5 %), siendo la atorvastatina (n=80.812; 78,0 %) y la lovastatina (n=12.621; 12,2 %) las más frecuentes. La dosis promedio de atorvastatina fue de 30,3 mg/día y el 49,9 % de sus usuarios recibía presentaciones de 40 mg o más. Un total de 9.258 (8,9 %) pacientes recibían fibratos y solo 780 (0,8 %) tomaban ezetimibe. El 94,9 % de casos recibió tratamiento en monoterapia hipolipemiante y el 97,3 % (n=100.813) tenía comedicaciones para comorbilidades, siendo las más frecuentes antihipertensivos (89,1 %), antiagregantes plaquetarios (57,8 %), antidiabéticos (31,5 %) y antiulcerosos (34,2 %).Conclusiones. La atorvastatina es actualmente el medicamento hipolipemiante más utilizado en este grupo de pacientes de Colombia, especialmente en monoterapia y a dosis cercanas a las definidas, aunque solo la mitad recibían dosis recibían dosis de alta intensidad. Se requieren nuevos estudios que verifiquen la efectividad de estos tratamientos
Composición y estructura de la ictiofauna del río Hondo, México-Belice, con base en el uso del arpón
ResumenSe determinó la composición y estructura de la ictiofauna del río Hondo y la variación espacial de éstas en función de los parámetros ambientales. Se realizaron 3 muestreos durante marzo, abril y mayo de 2012, en 6 sitios a lo largo del río. Los datos usados para determinar la estructura se obtuvieron con ayuda de un arpón de 58.5cm, utilizado durante 2h de buceo libre en cada punto de muestreo. Para complementar la lista de especies se utilizaron redes agalleras, palangres, nasas y anzuelos. Además, se realizó una revisión bibliográfica y se consultó material de la colección de peces de ECOSUR en Chetumal. La lista sistemática se conformó por 40 especies en 33 géneros, 18 familias y 11 órdenes. La familia mejor representada fue Cichlidae, incluida la especie exótica Oreochromis niloticus. Los parámetros ambientales que mejor describieron la variación de la distribución y abundancia en los peces en el río Hondo fueron: la anchura del río, distancia a la boca, transparencia, profundidad, concentración de oxígeno disuelto y conductividad. La relación entre las especies y las variables ambientales fue alta en ambos ejes (0.89 y 0.79). Ambientalmente, el río se puede zonificar en 3 partes, aunque su ictiofauna puede dividirse en 2 conjuntos principales.AbstractComposition and structure of the Hondo River ichthyofauna and its spatial variation were determined as a function of environmental parameters. Six sites along the river were sampled in March, April and May 2012. Data for estimating structure of fish assemblages was obtained by means of a 58.5cm harpoon during 2 hours of free diving at each sampling site. The species list for the study area was completed with the aid of gillnets, longlines, double-cone traps, and hook-and-line. In addition, a bibliographical research performed as well as the ichthyological collection of ECOSUR at Chetumal was checked. The systematic list includes 40 species in 33 genera, 18 families and 11 orders. The richest family was Cichlidae, including the exotic Oreochromis niloticus. The environmental parameters that best described distribution and abundance of fish in the Hondo River were river width, distance to mouth, transparency, depth, dissolved oxygen concentration, and conductivity. Correlation between species and environmental parameters was high in both axis (0.89 and 0.79). The river was classified into 3 environmental zones, although its fish fauna could be divided in 2 main assemblages
New record of the culpeo Lycalopex culpaeus (Mammalia: Canidae) in southwestern Colombia with remarks on its distribution in the country
Presentamos un nuevo registro del lobo de páramo (Lycalopex culpaeus) proveniente del suroccidente de Colombia y discutimos los registros y localidades previos de la especie para el país. La especie es conocida de tres localidades confirmadas, dos de las cuales poseen ejemplares de referencia, mientras que la tercera es presentada aquí, a partir de un registro fotográfico obtenido en el año 2011. Todas las localidades confirmadas se localizan en el Nudo de Los Pastos, departamento de Nariño, suroccidente de Colombia. Otras localidades y registros de la especie en la literatura requieren de evidencias adicionales que soporten la presencia de la especie en dichas zonas, mientras que los registros de la cordillera Central en el departamento del Valle del Cauca, Tolima y la cordillera Occidental en el departamento del Cauca son considerados aquí como erróneos.We present a new record of the culpeo (Lycalopex culpaeus) from southwestern Colombia, and discuss the previous records and localities of the species in the country. The species is known from three confirmed localities; two of them are represented by voucher specimens and the third is presented here based on a photography obtained on 2011. All confirmed localities are located in the Nudo de Los Pastos, Department of Nariño, southwestern Colombia. Other localities and records of the species in literature are in need of more evidence that corroborate the presence of the species in these areas, while the records from the Central Cordillera in the Departments of Valle del Cauca, Tolima, and from the Western Cordillera in the Department of Cauca are considered erroneous
Rice Galaxy: An open resource for plant science
Background: Rice molecular genetics, breeding, genetic diversity, and allied research (such as rice-pathogen interaction) have adopted sequencing technologies and high-density genotyping platforms for genome variation analysis and gene discovery. Germplasm collections representing rice diversity, improved varieties, and elite breeding materials are accessible through rice gene banks for use in research and breeding, with many having genome sequences and high-density genotype data available. Combining phenotypic and genotypic information on these accessions enables genome-wide association analysis, which is driving quantitative trait loci discovery and molecular marker development. Comparative sequence analyses across quantitative trait loci regions facilitate the discovery of novel alleles. Analyses involving DNA sequences and large genotyping matrices for thousands of samples, however, pose a challenge to non−computer savvy rice researchers. Findings: The Rice Galaxy resource has shared datasets that include high-density genotypes from the 3,000 Rice Genomes project and sequences with corresponding annotations from 9 published rice genomes. The Rice Galaxy web server and deployment installer includes tools for designing single-nucleotide polymorphism assays, analyzing genome-wide association studies, population diversity, rice−bacterial pathogen diagnostics, and a suite of published genomic prediction methods. A prototype Rice Galaxy compliant to Open Access, Open Data, and Findable, Accessible, Interoperable, and Reproducible principles is also presented. Conclusions: Rice Galaxy is a freely available resource that empowers the plant research community to perform state-of-the-art analyses and utilize publicly available big datasets for both fundamental and applied science
Size and frequency of natural forest disturbances and Amazon carbon balance
Forest inventory studies in the Amazon indicate a large terrestrial carbon sink. However, field plots may fail to represent forest mortality processes at landscape-scales of tropical forests. Here we characterize the frequency distribution of disturbance events in natural forests from 0.01 ha to 2,651 ha size throughout Amazonia using a novel combination of forest inventory, airborne lidar and satellite remote sensing data. We find that small-scale mortality events are responsible for aboveground biomass losses of B1.28 Pg C y 1 over the entire Amazon region. We also find that intermediate-scale disturbances account for losses of B0.01 Pg C y 1 , and that the largest-scale disturbances as a result of blow-downs only account for losses of B0.003 Pg C y 1 . Simulation of growth and mortality indicates that even when all carbon losses from intermediate and large-scale disturbances are considered, these are outweighed by the net biomass accumulation by tree growth, supporting the inference of an Amazon carbon sink
Comunicar ciencia en México. Discursos y espacios sociales
La generación y divulgación de la ciencia y la tecnología es una tarea que implica contribuir al desarrollo de una cultura que vaya más allá del registro y difusión de los hechos y nombres científicos, al suponer la comprensión crítica de la labor propia como proceso socialmente contextualizado, enraizado en factores históricos, políticos, económicos y éticos. Los trabajos aquí presentados proponen asumir que la comunicación pública del conocimiento expresa también las controversias socio–científicas y la relación social de ciencia y tecnología en las condiciones imperantes de transición vertiginosa en la producción cultural, científica y tecnológica.ITESO, A.C.Consejo de Ciencia y Tecnología del Estado de Jalisc
Determinación del pH y recuento de mesófilos en carne de boquichico (Prochilodus nigricans) proveniente de los mercados de la ciudad de Pucallpa, Ucayali
The aim of this study was to determine the pH and the count of mesophiles in black prochilodus (“boquichico”) meat (Prochidolus nigricans), from the markets of the city of Pucallpa, Ucayali. In total, 115 samples of boquichico specimens were collected from the 23 stalls distributed in the 5 markets of the city (5 samples per stall, considering the stall as a lot), through a non-probabilistic convenience sampling. The processing was carried out by measuring the pH of the meat and the analysis for the count of mesophiles with the SPC method (aerobic plate count). The averages of the pH values in boquichico meat by market were below the neutral value (pH=7.0), but were higher in the samples from markets 3 and 5; likewise, the mesophilic counts in meat exceeded the Maximum Allowable Limits in 4 of the 23 stalls (two from market N° 1, one from market N° 2 and one from market N° 3). It is concluded that the boquichico meat commercialized in the markets of the city of Pucallpa is not suitable for consumption in three stalls in two Callería markets and in one stall in a market in Manantay.El objetivo del estudio fue determinar el pH y el recuento de mesófilos en carne de boquichico (Prochidolus nigricans), proveniente de los mercados de la ciudad de Pucallpa, Ucayali. Se recolectaron 115 muestras de ejemplares de boquichico de los 23 puestos de venta distribuidos en los 5 mercados de la ciudad (5 muestras por puesto, considerando al puesto de venta como un lote), mediante un muestreo no probabilístico por conveniencia. El procesamiento se realizó mediante la medición del pH de la carne y el análisis para el recuento de mesófilos con el método SPC (conteo de placas aeróbicas). Los promedios de los valores de pH en la carne de boquichico por mercado estuvieron por debajo del valor neutro (pH = 7.0), pero fueron mayores en las muestras procedentes de los mercados 3 y 5; asimismo, los recuentos de mesófilos en la carne sobrepasaron a los Límites Máximos Permisibles en 4 de los 23 puestos de venta (dos del mercado N.° 1, uno del mercado N.° 2 y uno del mercado N.° 3). Se concluye que la carne de boquichico comercializada en los mercados de la ciudad de Pucallpa no es apta para su consumo en tres puestos en dos mercados de Callería y en un puesto de un mercado en Manantay
Measurement of the α ratio and (n, γ) cross section of 235U from 0.2 to 200 eV at n_TOF
We measured the neutron capture-to-fission cross-section ratio (α ratio) and the capture cross section of 235U
between 0.2 and 200 eV at the n_TOF facility at CERN. The simultaneous measurement of neutron-induced
capture and fission rates was performed by means of the n_TOF BaF2 Total Absorption Calorimeter (TAC), used
for detection of γ rays, in combination with a set of micromegas detectors used as fission tagging detectors.
The energy dependence of the capture cross section was obtained with help of the 6
Li(n,t) standard reaction
determining the n_TOF neutron fluence; the well-known integral of the 235U(n, f ) cross section between 7.8
and 11 eV was then used for its absolute normalization. The α ratio, obtained with slightly higher statistical
fluctuations, was determined directly, without need for any reference cross section. To perform the analysis
of this measurement we developed a new methodology to correct the experimentally observed effect that the
probabilities of detecting a fission reaction in the TAC and the micromegas detectors are not independent. The
results of this work have been used in a new evaluation of 235U performed within the scope of the Collaborative
International Evaluated Library Organisation (CIELO) Project, and are consistent with the ENDF/B-VIII.0 and
JEFF-3.3 capture cross sections below 4 eV and above 100 eV. However, the measured capture cross section is
on average 10% larger between 4 and 100 eV.Ministerio de Economía, Industria y Competitividad de España. FPA2014-53290-C2-1, FPA2016-76765- P y FPA2017-82647-P7º Programa Marco CHANDA de la Comisión Europea. FP7-60520
Updating the distribution of Dicrodon guttulatum Duméril & Bibron, 1839 (Reptilia, Teiidae) with a disjunct population in the eastern slope of the Peruvian Andes
We report a disjunct population of Dicrodon guttulatum Duméril & Bibron, 1839 on the eastern slope of the Cordillera Occidental in the inter-Andean Seasonally Dry Forests of the Marañón River, in the Departments of Cajamarca and Piura in northwestern Peru. We include an updated range distribution map using records from museum specimens, the Global Biodiversity Information Facility, and available photographic records on iNaturalist. In addition, we identify widespread cultivation of rice crops as the main threat to D. guttulatum in the inter-Andean Seasonally Dry Forests of the Marañón
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