Peaceful giant ground beetles: The genus Tefflus Latreille (Coleoptera: Carabidae) in the Republic of South Africa

Two species of the genus Tefflus Latreille (Coleoptera: Carabidae), commonly known as “peaceful giant ground beetles,” are recorded from the Republic of South Africa: T. carinatus carinatus Klug and T. meyerlei delagorguei Guérin-Méneville. Distribution records from the Republic of South Africa are summarized and mapped for both species. Tefflus c. carinatus has been collected in KwaZulu-Natal and Mpumalanga Provinces, while T. m. delagorguei has been recorded from Free State, Gauteng, KwaZulu-Natal, Limpopo, and Mpumalanga Provinces. Adults of both species are illustrated. Seasonal and temporal activity patterns and defensive and foraging behaviors are characterized for T. m. delagorguei based on recent field studies in the Kruger National Park, Republic of South Africa

Peaceful giant ground beetles: The genus Tefflus Latreille (Coleoptera: Carabidae) in the Republic of South Africa

Mawdsley, Jonathan R., Sithole, Hendrik, Mawdsley, Alice S. (2011): Peaceful giant ground beetles: The genus Tefflus Latreille (Coleoptera: Carabidae) in the Republic of South Africa. Insecta Mundi 2011 (181): 1-7, DOI: http://doi.org/10.5281/zenodo.516104

Cypholoba localities

List of collecting localities for Cypholoba species in the Republic of South Africa, based on museum specimen data from the following collections: Field Museum of Natural History, Chicago, Illinois (FMNH); Kruger National Park Museum (Scientific Services), Skukuza, South Africa (KNPC); South African National Collection of Insects, Pretoria, South Africa (SANC); National Museum of Natural History, Smithsonian Institution, Washington, D.C. (NMNH); Transvaal Museum, Pretoria, South Africa (TMSA)

The Egyptian Predynastic and State Formation

When the archaeology of Predynastic Egypt was last appraised in this journal, Savage (2001a, p. 101) expressed optimism that “a consensus appears to be developing that stresses the gradual development of complex society in Egypt.” The picture today is less clear, with new data and alternative theoretical frameworks challenging received wisdom over the pace, direction, and nature of complex social change. Rather than an inexorable march to the beat of the neo-evolutionary drum, primary state formation in Egypt can be seen as a more syncopated phenomenon, characterized by periods of political experimentation and shifting social boundaries. Notably, field projects in Sudan and the Egyptian Delta together with new dating techniques have set older narratives of development into broader frames of reference. In contrast to syntheses that have sought to measure abstract thresholds of complexity, this review of the period between c. 4500 BC and c. 3000 BC transcends analytical categories by adopting a practice-based examination of multiple dimensions of social inequality and by considering how the early state may have become a lived reality in Egypt around the end of the fourth millennium BC

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

We performed a meta-analysis of five genome-wide association studies to identify common variants influencing colorectal cancer (CRC) risk comprising 8,682 cases and 9,649 controls. Replication analysis was performed in case-control sets totaling 21,096 cases and 19,555 controls. We identified three new CRC risk loci at 6p21 (rs1321311, near CDKN1A; P = 1.14 × 10 -10), 11q13.4 (rs3824999, intronic to POLD3; P = 3.65 × 10 -10) and Xp22.2 (rs5934683, near SHROOM2; P = 7.30 × 10 -10) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC.</p

The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis

© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine

Prospective observational cohort study on grading the severity of postoperative complications in global surgery research

Background The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs). Methods This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs. Results A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59). Conclusion Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally

Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries

This was an investigator initiated study funded by Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London