Analysis of EZproxy server logs to visualise research activity in Curtin’s online library

© 2019, Emerald Publishing Limited. Purpose: The purpose of this paper is to develop data visualisation proof of concept prototypes that will enable the Curtin University Library team to explore its users’ information-seeking behaviour and collection use online by analysing the library’s EZproxy logs. Design/methodology/approach: Curtin Library’s EZproxy log file data from 2013 to 2017 is used to develop the data visualisation prototypes using Unity3D software. Findings: Two visualisation prototypes from the EZproxy data set are developed. The first, “Global Visualisation of Curtin Research Activity”, uses a geographical map of the world as a platform to show where each research request comes from, the time each is made and the file size of the request. The second prototype, “Database Usage Visualisation”, shows the use of the library’s various subscription databases by staff and students daily, over a month in April 2017. Research limitations/implications: The paper has following limitations: working to a tight timeline of ten weeks; time taken to cleanse noise data; and requirements for storing and hosting the voluminous data sets. Practical implications: The prototypes provide visual evidence of the use of Curtin Library’s digital resources at any time and from anywhere by its users, demonstrating the demand for the library’s online service offerings. These prototype evidence-based data visualisations empower the library to communicate in a compelling and interesting way how its services and subscriptions support Curtin University’s missions. Originality/value: The paper provides innovative approaches to create immersive 3D data visualisation prototypes to make sense of complex EZproxy data sets

Construction of Genetic Linkage Maps From a Hybrid Family of Large Yellow Croaker (Larimichthys crocea)

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PENGARUH PENDEKATAN REALISTIC MATHEMATICS EDUCATION TERHADAP KEMAMPUAN BERPIKIR KRITIS DAN KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SEKOLAH DASAR

Kemampuan berpikir kritis dan kemampuan pemecahan masalah matematis merupakan kemampuan yang sangat penting yang harus dimiliki siswa Sekolah Dasar. Hal ini akan membantu dalam mengembangkan potensi dirinya, dengan menitikberatkan pada kemampuan dalam berpikir dan bertindak secara normatif, dan siap bernalar dari apa yang dilihat maupun didengar sehingga dapat menyelesaikan permasalahan yang dihadapinya dalam kehidupan sehari-hari, oleh karena itu peranan guru sebagai tenaga pendidik secara professional menjadi penentu dalam menjembatani siswa melalui pembelajaran yang berkualitas. Namun kenyataannya berkaitan dengan proses pembelajaran matematika di SD proses pembelajaran yang dilaksanakan belum memberikan kesempatan siswa dalam menggali potensi dirinya dalam berpikir kritis dan menyelesaikan permasalahan. Sehingga perlu dicari alternatif pembelajaran yang dapat meningkatkan kemampuan berpikir kritis dan kemampuan pemecahan masalah. Pendekatan Realistic Mathematics Education merupakan salah satu alternatif yang digunakan untuk meningkatkan kemampuan berpikir kritis dan kemampuan pemecahan masalah matematis. Penelitian ini bertujuan untuk mengetahui apakah pendekatan Realistic Mathematics Education dapat meningkatkan kemampuan berpikir kritis dan kemampuan pemecahan masalah matematis dalam pembelajaran matematika di Sekolah Dasar. Penelitian ini dilaksanakan menggunakan metode kuasi eksperimen dengan desain kelompok kontrol non-Ekuivalen. Sampel dalam penelitian adalah siswa kelas IV pada salah satu SD di Kabupaten Garut. Pengumpulan data dilakukan dengan tes berbentuk uraian dan lembar observasi selama proses pembelajaran. Untuk pengolahan data digunakan program SPSS versi 20. Berdasarkan hasil penelitian berupa skor N-gain dianalisis dengan menggunakan uji t-tes. Hasil penelitian yang dianalisis menunjukkan bahwa terdapat peningkatan kemampuan berpikir kritis dan kemampuan pemecahan masalah matematis yang belajar melalui pendekatan Realistic Mathematics Education (RME) dengan yang menggunakan pembelajaran biasa. Jadi dapat disimpulkan peningkatan kemampuan berpikir kritis dan kemampuan pemecahan masalah matematis dengan menggunakan Realistic Mathematics Education (RME) lebih baik dari siswa yang mendapatkan pembelajaran biasa ---------- Critical thinking skills and mathematical problem solving ability is a very important capability that should be owned by elementary school students. These abilities would help students to improve their potential, with concern on the ability to think and act as normative, and ready to have a reason of what is seen and heard so that they can solve their problems in daily life, therefore the role of the teacher as professional educators be decisive in bridging the students through quality learning. But in the reality, relates to the process of learning mathematics in elementary school, learning process which implemented yet provide an opportunity for students to explore their potential in critical thinking to solve the problems. so it is necessary to find an alternative learning that can improve critical thinking skills and problem solving skills. Realistic Mathematics Education approach is one alternative that is used to improve critical thinking skills and mathematical problem-solving abilities. This research aims to determine whether Realistic Mathematics Education approach can improve the ability of critical thinking and mathematical problem solving ability in mathematics in elementary school. This research was conducted using a quasi-experimental design with a control group of non-Equivalent. Samples were fourth grade students in one elementary school in Garut. Data collected by the description and the sheet-shaped test observations during the learning process. For data processing used SPSS version 20. Based on the results of research in the form of N-gain scores were analyzed using t-test, which analyzed research results show that there are increasing in the ability of critical thinking and problem solving skills are learned through mathematical approach Realistic Mathematics Education (RME) with the use of regular learning. So we can conclude the increase in critical thinking skills and mathematical problem-solving abilities by using Realistic Mathematics Education (RME) is better than the students who get regular learnin

Identification of quantitative genetic components of fitness variation in farmed, hybrid and native salmon in the wild

-Feral animals represent an important problem in many ecosystems due to interbreeding with wild conspecifics. Hybrid offspring from wild and domestic parents are often less adapted to local environment and ultimately, can reduce the fitness of the native population. This problem is an important concern in Norway, where each year, hundreds of thousands of farm Atlantic salmon escape from fish farms. Feral fish outnumber wild populations, leading to a possible loss of local adaptive genetic variation and erosion of genetic structure in wild populations. Studying the genetic factors underlying relative performance between wild and domesticated conspecific can help to better understand how domestication modifies the genetic background of populations, and how it may alter their ability to adapt to the natural environment. Here, based upon a large-scale release of wild, farm and wild x farm salmon crosses into a natural river system, a genome-wide quantitative trait locus (QTL) scan was performed on the offspring of 50 full-sib families, for traits related to fitness (length, weight, condition factor and survival). Six QTLs were detected as significant contributors to the phenotypic variation of the first three traits, explaining collectively between 9.8 and 14.8% of the phenotypic variation. The seventh QTL had a significant contribution to the variation in survival, and is regarded as a key factor to understand the fitness variability observed among salmon in the river. Interestingly, strong allelic correlation within one of the QTL regions in farmed salmon might reflect a recent selective sweep due to artificial selection

Reduced primary patency rate in diabetic patients after percutaneous intervention results from more frequent presentation with limb-threatening ischemia

ObjectiveAlthough patients with diabetes are at increased risk of amputation from peripheral vascular disease, excellent limb-salvage rates have been achieved with aggressive surgical revascularization. It is less clear whether patients with diabetes will fare as well as nondiabetics after undergoing percutaneous lower extremity revascularization, a modality which is becoming increasingly utilized for this disease process. This study aimed to assess differential outcomes in between diabetics and nondiabetics in lower extremity percutaneous interventions.MethodsWe retrospectively studied 291 patients with respect to patient variables, complications, and outcomes for percutaneous interventions performed for peripheral occlusive disease between 2002 and 2005. Tibial vessel run-off was assessed by angiography. Patency (assessed arterial duplex) was expressed by Kaplan-Meier method and log-rank analysis. Mean follow-up was 11.6 months (range 1 to 56 months).ResultsA total of 385 interventions for peripheral occlusive disease with claudication (52.2%), rest pain (16.4%), or tissue loss (31.4%) were analyzed, including 336 primary interventions and 49 reinterventions (mean patient age 73.9 years, 50.8% male). Comorbidities included diabetes mellitus (57.2%), chronic renal insufficiency (18.4%), hemodialysis (3.8%), hypertension (81.9%), hypercholesterolemia (57%), coronary artery disease (58%), tobacco use (63.2%). Diabetics were significantly more likely to be female (55.3% vs 40.8%), and suffer from CRI (23.5% vs 12.0%), a history of myocardial infarction (36.5% vs 18.0%), and <three-vessel tibial outflow (83.5% vs 71.8%), compared with nondiabetics, although all other comorbidities and lesion characteristics were equivalent between these groups. Overall primary patency (± SE) at 6, 12, and 18 months was 85 ± 2%, 63 ± 3% and 56 ± 4%, respectively. Patients with diabetes suffered reduced primary patency at 1 year compared with nondiabetics. For nondiabetics, primary patency was 88 ± 2%, 71 ± 4%, and 58 ± 4% at 6, 12, and 18 months, while for diabetics it was 82 ± 2%, 53 ± 4%, and 49 ± 4%, respectively (P = .05). Overall secondary patency at 6, 12, and 18 months was 88 ± 2%, 76 ± 3%, and 69 ± 3%, and did not vary by diabetes status. One-year limb salvage rate was 88.3% for patients with limb-threatening ischemia, which was also similar between diabetics and nondiabetics. While univariate analysis revealed that female gender, <three-vessel tibial outflow, and a history of tobacco use were all predictive of reduced primary patency (P < .05), none of these factors significantly impacted secondary patency or limb-salvage rate. Furthermore, only limb-threatening ischemia remained a significant predictor of outcome on multivariate analysis, suggesting that the poorer primary patency in diabetics is related primarily to their propensity to present with limb-threatening disease compared with nondiabetics.ConclusionPatients with diabetes demonstrate reduced primary patency rates after percutaneous treatment of lower extremity occlusive disease, most likely due to their advanced stage of disease at presentation. However, despite a higher reintervention rate, diabetics and others with risk factors predictive of reduced primary patency can attain equivalent short-term secondary patency and limb-salvage rates. Therefore, these patient characteristics should not be considered contraindications to endovascular therapy

Footprints of directional selection in wild atlantic salmon populations: Evidence for parasite-driven evolution?

Mechanisms of host-parasite co-adaptation have long been of interest in evolutionary biology; however, determining the genetic basis of parasite resistance has been challenging. Current advances in genome technologies provide new opportunities for obtaining a genome-scale view of the action of parasite-driven natural selection in wild populations and thus facilitate the search for specific genomic regions underlying inter-population differences in pathogen response. European populations of Atlantic salmon (Salmo salar L.) exhibit natural variance in susceptibility levels to the ectoparasite Gyrodactylus salaris Malmberg 1957, ranging from resistance to extreme susceptibility, and are therefore a good model for studying the evolution of virulence and resistance. However, distinguishing the molecular signatures of genetic drift and environment-associated selection in small populations such as land-locked Atlantic salmon populations presents a challenge, specifically in the search for pathogen-driven selection. We used a novel genome-scan analysis approach that enabled us to i) identify signals of selection in salmon populations affected by varying levels of genetic drift and ii) separate potentially selected loci into the categories of pathogen (G. salaris)-driven selection and selection acting upon other environmental characteristics. A total of 4631 single nucleotide polymorphisms (SNPs) were screened in Atlantic salmon from 12 different northern European populations. We identified three genomic regions potentially affected by parasite-driven selection, as well as three regions presumably affected by salinity-driven directional selection. Functional annotation of candidate SNPs is consistent with the role of the detected genomic regions in immune defence and, implicitly, in osmoregulation. These results provide new insights into the genetic basis of pathogen susceptibility in Atlantic salmon and will enable future searches for the specific genes involved

Complex genetic diversity patterns of cryptic, sympatric brown trout (Salmo trutta) populations in tiny mountain lakes

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A linkage map of transcribed single nucleotide polymorphisms in rohu (Labeo rohita) and QTL associated with resistance to Aeromonas hydrophila

Background Production of carp dominates world aquaculture. More than 1.1 million tonnes of rohu carp, Labeo rohita (Hamilton), were produced in 2010. Aeromonas hydrophila is a bacterial pathogen causing aeromoniasis in rohu, and is a major problem for carp production worldwide. There is a need to better understand the genetic mechanisms affecting resistance to this disease, and to develop tools that can be used with selective breeding to improve resistance. Here we use a 6 K SNP array to genotype 21 full-sibling families of L. rohita that were experimentally challenged intra-peritoneally with a virulent strain of A. hydrophila to scan the genome for quantitative trait loci associated with disease resistance. Results In all, 3193 SNPs were found to be informative and were used to create a linkage map and to scan for QTL affecting resistance to A. hydrophila. The linkage map consisted of 25 linkage groups, corresponding to the number of haploid chromosomes in L. rohita. Male and female linkage maps were similar in terms of order, coverage (1384 and 1393 cM, respectively) and average interval distances (1.32 and 1.35 cM, respectively). Forty-one percent of the SNPs were annotated with gene identity using BLAST (cut off E-score of 0.001). Twenty-one SNPs mapping to ten linkage groups showed significant associations with the traits hours of survival and dead or alive (P <0.05 after Bonferroni correction). Of the SNPs showing significant or suggestive associations with the traits, several were homologous to genes of known immune function or were in close linkage to such genes. Genes of interest included heat shock proteins (70, 60, 105 and “small heat shock proteins”), mucin (5b precursor and 2), lectin (receptor and CD22), tributyltin-binding protein, major histocompatibility loci (I and II), complement protein component c7-1, perforin 1, ubiquitin (ligase, factor e4b isoform 2 and conjugation enzyme e2 c), proteasome subunit, T-cell antigen receptor and lymphocyte specific protein tyrosine kinase. Conclusions A panel of markers has been identified that will be validated for use with both genomic and marker-assisted selection to improve resistance of L. rohita to A. hydrophila

Genetic differences between wild and hatchery-bred brown trout (Salmo trutta L.) in single nucleotide polymorphisms linked to selective traits

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2017 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd.publishedVersio

The emergence of supergenes from inversions in Atlantic salmon

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